Carbon efficient production of chemicals with yeasts.
bioeconomy
carbon balance
industrial biotechnology
metabolic engineering
Journal
Yeast (Chichester, England)
ISSN: 1097-0061
Titre abrégé: Yeast
Pays: England
ID NLM: 8607637
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
revised:
16
10
2023
received:
04
07
2023
accepted:
29
10
2023
medline:
17
12
2023
pubmed:
24
11
2023
entrez:
24
11
2023
Statut:
ppublish
Résumé
Microbial metabolism offers a wide variety of opportunities to produce chemicals from renewable resources. Employing such processes of industrial biotechnology provides valuable means to fight climate change by replacing fossil feedstocks by renewable substrate to reduce or even revert carbon emission. Several yeast species are well suited chassis organisms for this purpose, illustrated by the fact that the still largest microbial production of a chemical, namely bioethanol is based on yeast. Although production of ethanol and some other chemicals is highly efficient, this is not the case for many desired bulk chemicals. One reason for low efficiency is carbon loss, which decreases the product yield and increases the share of total production costs that is taken by substrate costs. Here we discuss the causes for carbon loss in metabolic processes, approaches to avoid carbon loss, as well as opportunities to incorporate carbon from CO
Substances chimiques
Carbon
7440-44-0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
583-593Subventions
Organisme : Austrian Research Promotion Agency
Organisme : European Union's Horizon 2020
ID : 101000441
Organisme : Austrian Science Fund
ID : M2891
Informations de copyright
© 2023 The Authors. Yeast published by John Wiley & Sons Ltd.
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