Tramadol-paracetamol for postoperative pain after spine surgery - A randomized, double-blind, placebo-controlled study.
Humans
Pain, Postoperative
/ drug therapy
Tramadol
/ administration & dosage
Double-Blind Method
Acetaminophen
/ administration & dosage
Male
Female
Middle Aged
Analgesics, Opioid
/ administration & dosage
Patient Satisfaction
Oxycodone
/ administration & dosage
Analgesics, Non-Narcotic
/ administration & dosage
Adult
Spine
/ surgery
Treatment Outcome
Ibuprofen
/ administration & dosage
Pain Measurement
Aged
pain
postoperative
spine surgery
tramadol–paracetamol
Journal
Scandinavian journal of pain
ISSN: 1877-8879
Titre abrégé: Scand J Pain
Pays: Germany
ID NLM: 101520867
Informations de publication
Date de publication:
01 Jan 2024
01 Jan 2024
Historique:
received:
26
09
2023
accepted:
05
04
2024
medline:
6
5
2024
pubmed:
6
5
2024
entrez:
6
5
2024
Statut:
epublish
Résumé
Multimodal pain management is one component in enhanced recovery after surgery protocol. Here we evaluate the efficacy of tramadol-paracetamol in acute postoperative pain and pain outcome at 12 months after spine surgery in randomized, double-blind, placebo-controlled trial. We randomized 120 patients undergoing spine surgery to receive, for add-on pain management, two tramadol-paracetamol 37.5 mg/325 mg ( At 1 week after surgery, patients' satisfaction with pain medication was similarly high in the two groups, 75% [interquartile range, 30%] in the placebo group and 70% [40%] in the tramadol-paracetamol group ( Add-on pain treatment with tramadol-paracetamol did not enhance patients' satisfaction with early pain management after back surgery.
Identifiants
pubmed: 38708610
pii: sjpain-2023-0105
doi: 10.1515/sjpain-2023-0105
doi:
Substances chimiques
Tramadol
39J1LGJ30J
Acetaminophen
362O9ITL9D
Analgesics, Opioid
0
Oxycodone
CD35PMG570
Analgesics, Non-Narcotic
0
Ibuprofen
WK2XYI10QM
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024 the author(s), published by De Gruyter.
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