Exploitation of erythrosine B as a fluorometric marker for lurasidone determination through electrostatic attraction; application to content uniformity test.
content uniformity testing
erythrosine B
fluorescence quenching
greenness evaluation
lurasidone
Journal
Luminescence : the journal of biological and chemical luminescence
ISSN: 1522-7243
Titre abrégé: Luminescence
Pays: England
ID NLM: 100889025
Informations de publication
Date de publication:
Jul 2024
Jul 2024
Historique:
revised:
05
07
2024
received:
06
04
2024
accepted:
15
07
2024
medline:
26
7
2024
pubmed:
26
7
2024
entrez:
26
7
2024
Statut:
ppublish
Résumé
A recently developed antipsychotic drug, lurasidone, was determined using a simple, sensitive, and eco-friendly spectrofluorimetric approach. The suggested approach was based on the quantifiable quenching impact of lurasidone on the inherent fluorescence of erythrosine B in an acidic environment employing a Teorell-Stenhagen buffer (pH 4). Following excitation at 530 nm, the quenching of erythrosine B fluorescence was monitored at 552 nm. The system variables were systematically optimized to enhance the formation of the lurasidone-erythrosine B ion pair for analytical purposes. A linear calibration graph was built in the range of 20-600 ng mL
Substances chimiques
Lurasidone Hydrochloride
O0P4I5851I
Erythrosine
PN2ZH5LOQY
Tablets
0
Antipsychotic Agents
0
Fluorescent Dyes
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e4845Informations de copyright
© 2024 John Wiley & Sons Ltd.
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