N-glycosylation of SnRK2s affects NADPH maintenance in peroxisomes during prolonged ABA signalling.

Arabidopsis / metabolism Peroxisomes / metabolism Arabidopsis Proteins / metabolism Protein Serine-Threonine Kinases / metabolism Glycosylation Signal Transduction Abscisic Acid / metabolism NADP / metabolism Gene Expression Regulation, Plant Hydrogen Peroxide / metabolism Endoplasmic Reticulum / metabolism Plant Roots / metabolism Cell Nucleus / metabolism Golgi Apparatus / metabolism Pentose Phosphate Pathway Plant Growth Regulators / metabolism

Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
05 Aug 2024
Historique:
received: 19 05 2023
accepted: 19 07 2024
medline: 6 8 2024
pubmed: 6 8 2024
entrez: 5 8 2024
Statut: epublish

Résumé

Unfavourable conditions, such as prolonged drought and high salinity, pose a threat to the survival and agricultural yield of plants. The phytohormone ABA plays a key role in the regulation of plant stress adaptation and is often maintained at high levels for extended periods. While much is known about ABA signal perception and activation in the early signalling stage, the molecular mechanism underlying desensitization of ABA signalling remains largely unknown. Here we demonstrate that in the endoplasmic reticulum (ER)-Golgi network, the key regulators of ABA signalling, SnRK2.2/2.3, undergo N-glycosylation, which promotes their redistribution from the nucleus to the peroxisomes in Arabidopsis roots and influences the transcriptional response in the nucleus during prolonged ABA signalling. On the peroxisomal membrane, SnRK2s can interact with glucose-6-phosphate (G6P)/phosphate translocator 1 (GPT1) to maintain NADPH homeostasis through increased activity of the peroxisomal oxidative pentose phosphate pathway (OPPP). The resulting maintenance of NADPH is essential for the modulation of hydrogen peroxide (H

Identifiants

DOI: 10.1038/s41467-024-50720-3 PMID: 39103337
pubmed: 39103337
doi: 10.1038/s41467-024-50720-3
pii: 10.1038/s41467-024-50720-3
doi:

Substances chimiques

Arabidopsis Proteins 0
Protein Serine-Threonine Kinases EC 2.7.11.1
Abscisic Acid 72S9A8J5GW
SnRK2 protein, Arabidopsis 0
NADP 53-59-8
Hydrogen Peroxide BBX060AN9V
Plant Growth Regulators 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

6630

Subventions

Organisme : National Natural Science Foundation of China (National Science Foundation of China)
ID : 31970292
Organisme : Natural Science Foundation of Shandong Province (Shandong Provincial Natural Science Foundation)
ID : ZR2021MC012

Informations de copyright

© 2024. The Author(s).

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Auteurs

Junyao Lu (J)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China.
ORCID: 0009-0000-5695-1647

Ning Li (N)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China.
ORCID: 0009-0002-8810-4156

Gaojian Li (G)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China.
ORCID: 0009-0003-3625-5849

Ziang Tian (Z)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China.
ORCID: 0009-0002-0890-4648

Lianping Shi (L)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China.
ORCID: 0009-0008-0722-2593

Yan Wang (Y)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China.
ORCID: 0009-0008-1871-7321

Yingao Cai (Y)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China.

Kaiyuan Zhang (K)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China.

Wanting Sun (W)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China.
ORCID: 0009-0006-2459-1986

Danyang Wang (D)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China.
ORCID: 0009-0002-4263-2068

Jinxin Lin (J)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China.
ORCID: 0009-0003-0543-6743

Jinguang Huang (J)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China.

Changai Wu (C)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China.
ORCID: 0000-0003-4053-8262

Kang Yan (K)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China.
ORCID: 0000-0001-6124-4242

Shizhong Zhang (S)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China.

Chengchao Zheng (C)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China. cczheng@sdau.edu.cn.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China. cczheng@sdau.edu.cn.

Guodong Yang (G)

College of Life Sciences, Shandong Agricultural University, Taian, Shandong, PR China. gdyang@sdau.edu.cn.
National Key Laboratory of Wheat Improvement, Shandong Agricultural University, Taian, Shandong, PR China. gdyang@sdau.edu.cn.
ORCID: 0000-0002-0652-2016

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Brassicaceae › Arabidopsis › N-glycosylation of SnRK2s affects NADPH...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Vésicules cytoplasmiques › Granulations cytoplasmiques › Microcorps › Péroxysomes › N-glycosylation of SnRK2s affects NADPH...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines végétales › Protéines d'Arabidopsis › N-glycosylation of SnRK2s affects NADPH...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein-Serine-Threonine Kinases › N-glycosylation of SnRK2s affects NADPH...
questionsmedicales.fr › Métabolisme › Métabolisme glucidique › Glycosylation › N-glycosylation of SnRK2s affects NADPH...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › N-glycosylation of SnRK2s affects NADPH...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Sesquiterpènes › Sesquiterpènes monocycliques › Acide abscissique › N-glycosylation of SnRK2s affects NADPH...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléotides adényliques › NADP › N-glycosylation of SnRK2s affects NADPH...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Régulation de l'expression des gènes végétaux › N-glycosylation of SnRK2s affects NADPH...
questionsmedicales.fr › Composés chimiques organiques › Radicaux libres › Peroxydes › Peroxyde d'hydrogène › N-glycosylation of SnRK2s affects NADPH...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Réticulum endoplasmique › N-glycosylation of SnRK2s affects NADPH...
questionsmedicales.fr › Structures de plante › Racines de plante › N-glycosylation of SnRK2s affects NADPH...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Noyau de la cellule › N-glycosylation of SnRK2s affects NADPH...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Appareil de Golgi › N-glycosylation of SnRK2s affects NADPH...
questionsmedicales.fr › Métabolisme › Voies et réseaux métaboliques › Voie des pentoses phosphates › N-glycosylation of SnRK2s affects NADPH...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Substances de croissance › Facteur de croissance végétal › N-glycosylation of SnRK2s affects NADPH...