Humans Plant Extracts / pharmacology Neuroprotective Agents / pharmacology Benzo(a)pyrene / toxicity Cell Line, Tumor Thymelaeaceae / chemistry Gene Expression Profiling RNA-Seq Plant Leaves / chemistry Neurons / drug effects Transcriptome / drug effects Cell Differentiation / drug effects Neurogenesis / drug effects Molecular Docking Simulation Cell Survival / drug effects
RNA sequencing agarwood molecular docking neurite outgrowth neurotoxicity polycyclic aromatic hydrocarbons signaling pathways

Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
16 Aug 2024
Historique:
received: 27 07 2024
revised: 12 08 2024
accepted: 13 08 2024
medline: 1 9 2024
pubmed: 31 8 2024
entrez: 29 8 2024
Statut: epublish

Résumé

Benzo[a]pyrene (B[a]P) is known to inhibit neurodifferentiation and induce neurodegeneration. Agarwood or

Identifiants

DOI: 10.3390/nu16162727 PMID: 39203863
pubmed: 39203863
pii: nu16162727
doi: 10.3390/nu16162727
pii:
doi:

Substances chimiques

Plant Extracts 0
Neuroprotective Agents 0
Benzo(a)pyrene 3417WMA06D

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Thailand Science research and Innovation Fund Chulalongkorn University
ID : HEA665300111

Auteurs

Nattaporn Pattarachotanant (N)

Center of Excellence on Natural Products for Neuroprotection and Anti-Ageing (Neur-Age Natura), Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
ORCID: 0000-0002-2710-4980

Suporn Sukjamnong (S)

Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Chulalongkorn Autism Research and Innovation Center of Excellence (Chula ACE), Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.

Panthakarn Rangsinth (P)

Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
ORCID: 0000-0001-7255-9012

Kamonwan Chaikhong (K)

Center of Excellence on Natural Products for Neuroprotection and Anti-Ageing (Neur-Age Natura), Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.

Chanin Sillapachaiyaporn (C)

Center of Excellence on Natural Products for Neuroprotection and Anti-Ageing (Neur-Age Natura), Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
ORCID: 0000-0003-1868-4079

George Pak-Heng Leung (GP)

Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
ORCID: 0000-0003-3529-9367

Valerie W Hu (VW)

Department of Biochemistry and Molecular Medicine, The George Washington University School of Medicine and Health Sciences, The George Washington University, Washington, DC 20037, USA.
ORCID: 0000-0002-3357-0777

Tewarit Sarachana (T)

Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Chulalongkorn Autism Research and Innovation Center of Excellence (Chula ACE), Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
ORCID: 0000-0003-4518-9399

Siriporn Chuchawankul (S)

Department of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
ORCID: 0000-0002-7627-0408

Tewin Tencomnao (T)

Center of Excellence on Natural Products for Neuroprotection and Anti-Ageing (Neur-Age Natura), Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
ORCID: 0000-0003-4177-2165

Anchalee Prasansuklab (A)

Center of Excellence on Natural Products for Neuroprotection and Anti-Ageing (Neur-Age Natura), Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
College of Public Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
ORCID: 0000-0001-8884-3077

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains ›
questionsmedicales.fr › Préparations pharmaceutiques › Extraits de plantes ›
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Neuroprotecteurs ›
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Pyrènes › Benzopyrènes › Benzo[a]pyrène ›
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale ›
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Thymelaeaceae ›
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de profil d'expression de gènes ›
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de séquence › Analyse de séquence d'ARN › RNA-Seq ›
questionsmedicales.fr › Structures de plante › Parties aériennes de plante › Feuilles de plante ›
questionsmedicales.fr › Cellules › Neurones ›
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Transcriptome ›
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Différenciation cellulaire ›
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Neurogenèse ›
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire ›
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Survie cellulaire ›