Adam Naj

Affiliations

Center for Clinical Epidemiology and Biostatistic, and the Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Publications (10)

A statistical framework for cross-tissue transcriptome-wide association analysis.

Nature genetics

Avec: Yiming Hu , Mo Li , Qiongshi Lu , Haoyi Weng , Jiawei Wang , Seyedeh M Zekavat , Zhaolong Yu , Boyang Li , Jianlei Gu , Sydney Muchnik , Yu Shi , Brian W Kunkle , Shubhabrata Mukherjee , Pradeep Natarajan , Adam Naj , Amanda Kuzma , Yi Zhao , Paul K Crane , Auteur inconnu , Hui Lu , Hongyu Zhao

Biobank-wide association scan identifies risk factors for late-onset Alzheimer's disease and endophenotypes.

eLife

Avec: Donghui Yan , Bowen Hu , Burcu F Darst , Shubhabrata Mukherjee , Brian W Kunkle , Yuetiva Deming , Logan Dumitrescu , Yunling Wang , Adam Naj , Amanda Kuzma , Yi Zhao , Hyunseung Kang , Sterling C Johnson , Cruchaga Carlos , Timothy J Hohman , Paul K Crane , Corinne D Engelman , Auteur inconnu , Qiongshi Lu

An X Chromosome Transcriptome Wide Association Study Implicates ARMCX6 in Alzheimer's Disease.

bioRxiv : the preprint server for biology

Avec: Xueyi Zhang , Lissette Gomez , Jennifer Below , Adam Naj , Eden Martin , Brian Kunkle , William S Bush

Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes.

Nature communications

Avec: Kurt Farrell , Jack Humphrey , Timothy Chang , Yi Zhao , Yuk Yee Leung , Pavel P Kuksa , Vishakha Patil , Wan-Ping Lee , Amanda B Kuzma , Otto Valladares , Laura B Cantwell , Hui Wang , Ashvin Ravi , Claudia De Sanctis , Natalia Han , Thomas D Christie , Robina Afzal , Shrishtee Kandoi , Kristen Whitney , Margaret M Krassner , Hadley Ressler , SoongHo Kim , Diana Dangoor , Megan A Iida , Alicia Casella , Ruth H Walker , Melissa J Nirenberg , Alan E Renton , Bergan Babrowicz , Giovanni Coppola , Towfique Raj , Günter U Höglinger , Ulrich Müller , Lawrence I Golbe , Huw R Morris , John Hardy , Tamas Revesz , Tom T Warner , Zane Jaunmuktane , Kin Y Mok , Rosa Rademakers , Dennis W Dickson , Owen A Ross , Li-San Wang , Alison Goate , Gerard Schellenberg , Daniel H Geschwind , Auteur inconnu , John F Crary , Adam Naj

Identification of novel genes for age-at-onset of Alzheimer's disease by combining quantitative and survival trait analyses.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Avec: Yi-Ju Li , Karen Nuytemans , Jong Ok La , Rong Jiang , Susan H Slifer , Shuming Sun , Adam Naj , Xiaoyi Raymond Gao , Eden R Martin

Association of Common and Rare Variants with Alzheimer's Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer's Disease Sequencing Project.

medRxiv : the preprint server for health sciences

Avec: Wan-Ping Lee , Seung Hoan Choi , Margaret G Shea , Po-Liang Cheng , Beth A Dombroski , Achilleas N Pitsillides , Nancy L Heard-Costa , Hui Wang , Katia Bulekova , Amanda B Kuzma , Yuk Yee Leung , John J Farrell , Honghuang Lin , Adam Naj , Elizabeth E Blue , Frederick Nusetor , Dongyu Wang , Eric Boerwinkle , William S Bush , Xiaoling Zhang , Philip L De Jager , Josée Dupuis , Lindsay A Farrer , Myriam Fornage , Eden Martin , Margaret Pericak-Vance , Sudha Seshadri , Ellen M Wijsman , Li-San Wang , Gerard D Schellenberg , Anita L Destefano , Jonathan L Haines , Gina M Peloso

Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Avec: Farid Rajabli , Giuseppe Tosto , Kara L Hamilton-Nelson , Brian W Kunkle , Badri N Vardarajan , Adam Naj , Patrice G Whitehead , Olivia K Gardner , William S Bush , Sanjeev Sariya , Richard P Mayeux , Lindsay A Farrer , Michael L Cuccaro , Jeffrey M Vance , Anthony J Griswold , Gerard D Schellenberg , Jonathan L Haines , Goldie S Byrd , Christiane Reitz , Gary W Beecham , Margaret A Pericak-Vance , Eden R Martin , Auteur inconnu

Novel early-onset Alzheimer-associated genes influence risk through dysregulation of glutamate, immune activation, and intracell signaling pathways.

Research square

Avec: Carlos Cruchaga , Joseph Bradley , Daniel Western , Ciyang Wang , Eder Lucio Da Fonseca , Achal Neupane , Jiji Kurup , NIcholas Ray , Melissa Jean-Francois , Priyanka Gorijala , Kristy Bergmann , John Budde , Eden Martin , Margaret Pericak-Vance , Michael Cuccaro , Brian Kunkle , John Morris , David Holtzman , Richard Perrin , Adam Naj , Jonathan Haines , Gerard Schellenberg , Victoria Fernandez , Christiane Reitz , Gary Beecham , Alzheimer's Disease Genetics Consortium , Charles F And Joanne Knight Alzheimer's Disease Research Ce Adrc

NIAGADS: A Comprehensive National Data Repository for Alzheimer's Disease and Related Dementia Genetics and Genomics Research.

medRxiv : the preprint server for health sciences

Avec: Amanda Kuzma , Otto Valladares , Emily Greenfest-Allen , Heather Nicaretta , Maureen Kirsch , Youli Ren , Zivadin Katanic , Heather White , Andrew Wilk , Lauren Bass , Jascha Brettschneider , Luke Carter , Jeffrey Cifello , Wei-Hsuan Chuang , Kaylyn Clark , Prabhakaran Gangadharan , Jacob Haut , Pei-Chuan Ho , Wenhwai Horng , Taha Iqbal , Yumi Jin , Peter Keskinen , Alexis Lerro Rose , Michelle K Moon , Joseph Manuel , Liming Qu , Flawless Robbins , Naveensri Saravanan , Jin Sha , Sam Tate , Yi Zhao , Auteur inconnu , Laura Cantwell , Jake Gardner , Shin-Yi Chou , Jung-Ying Tzeng , William Bush , Adam Naj , Pavel Kuksa , Wan-Ping Lee , Yuk Yee Leung , Gerard Schellenberg , Li-San Wang

Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Avec: Wan-Ping Lee , Seung Hoan Choi , Margaret G Shea , Po-Liang Cheng , Beth A Dombroski , Achilleas N Pitsillides , Nancy L Heard-Costa , Hui Wang , Katia Bulekova , Amanda B Kuzma , Yuk Yee Leung , John J Farrell , Honghuang Lin , Brian W Kunkle , Adam Naj , Elizabeth E Blue , Frederick Nusetor , Dongyu Wang , Eric Boerwinkle , William S Bush , Xiaoling Zhang , Philip L De Jager , Josée Dupuis , Lindsay A Farrer , Myriam Fornage , Eden Martin , Margaret Pericak-Vance , Sudha Seshadri , Ellen M Wijsman , Li-San Wang , Auteur inconnu , Gerard D Schellenberg , Anita L Destefano , Jonathan L Haines , Gina M Peloso

Réseau de co-auteurs

None None 6 collaborations

Brian W Kunkle 4 collaborations

Yi Zhao 4 collaborations

Eden Martin 4 collaborations

William S Bush 4 collaborations

Yuk Yee Leung 4 collaborations

Wan-Ping Lee 4 collaborations

Li-San Wang 4 collaborations

Amanda Kuzma 3 collaborations

Amanda B Kuzma 3 collaborations

Hui Wang 3 collaborations

Gerard Schellenberg 3 collaborations

Lindsay A Farrer 3 collaborations

Margaret Pericak-Vance 3 collaborations

Gerard D Schellenberg 3 collaborations

Jonathan L Haines 3 collaborations

Qiongshi Lu 2 collaborations

Shubhabrata Mukherjee 2 collaborations

Paul K Crane 2 collaborations

Brian Kunkle 2 collaborations

Otto Valladares 2 collaborations

Eden R Martin 2 collaborations

Seung Hoan Choi 2 collaborations

Margaret G Shea 2 collaborations

Po-Liang Cheng 2 collaborations

Beth A Dombroski 2 collaborations

Achilleas N Pitsillides 2 collaborations

Nancy L Heard-Costa 2 collaborations

Katia Bulekova 2 collaborations

John J Farrell 2 collaborations

Honghuang Lin 2 collaborations

Elizabeth E Blue 2 collaborations

Frederick Nusetor 2 collaborations

Dongyu Wang 2 collaborations

Eric Boerwinkle 2 collaborations

Xiaoling Zhang 2 collaborations

Philip L De Jager 2 collaborations

Josée Dupuis 2 collaborations

Myriam Fornage 2 collaborations

Sudha Seshadri 2 collaborations

Ellen M Wijsman 2 collaborations

Anita L Destefano 2 collaborations

Gina M Peloso 2 collaborations

Christiane Reitz 2 collaborations

Yiming Hu 1 collaboration

Mo Li 1 collaboration

Haoyi Weng 1 collaboration

Jiawei Wang 1 collaboration

Seyedeh M Zekavat 1 collaboration

Zhaolong Yu 1 collaboration

Boyang Li 1 collaboration

Jianlei Gu 1 collaboration

Sydney Muchnik 1 collaboration

Yu Shi 1 collaboration

Pradeep Natarajan 1 collaboration

Hui Lu 1 collaboration

Hongyu Zhao 1 collaboration

Donghui Yan 1 collaboration

Bowen Hu 1 collaboration

Burcu F Darst 1 collaboration

Yuetiva Deming 1 collaboration

Logan Dumitrescu 1 collaboration

Yunling Wang 1 collaboration

Hyunseung Kang 1 collaboration

Sterling C Johnson 1 collaboration

Cruchaga Carlos 1 collaboration

Timothy J Hohman 1 collaboration

Corinne D Engelman 1 collaboration

Xueyi Zhang 1 collaboration

Lissette Gomez 1 collaboration

Jennifer Below 1 collaboration

Kurt Farrell 1 collaboration

Jack Humphrey 1 collaboration

Timothy Chang 1 collaboration

Pavel P Kuksa 1 collaboration

Vishakha Patil 1 collaboration

Laura B Cantwell 1 collaboration

Ashvin Ravi 1 collaboration

Claudia De Sanctis 1 collaboration

Natalia Han 1 collaboration

Thomas D Christie 1 collaboration

Robina Afzal 1 collaboration

Shrishtee Kandoi 1 collaboration

Kristen Whitney 1 collaboration

Margaret M Krassner 1 collaboration

Hadley Ressler 1 collaboration

SoongHo Kim 1 collaboration

Diana Dangoor 1 collaboration

Megan A Iida 1 collaboration

Alicia Casella 1 collaboration

Ruth H Walker 1 collaboration

Melissa J Nirenberg 1 collaboration

Alan E Renton 1 collaboration

Bergan Babrowicz 1 collaboration

Giovanni Coppola 1 collaboration

Towfique Raj 1 collaboration

Günter U Höglinger 1 collaboration

Ulrich Müller 1 collaboration

Lawrence I Golbe 1 collaboration

Huw R Morris 1 collaboration

John Hardy 1 collaboration

Tamas Revesz 1 collaboration

Tom T Warner 1 collaboration

Zane Jaunmuktane 1 collaboration

Kin Y Mok 1 collaboration

Rosa Rademakers 1 collaboration

Dennis W Dickson 1 collaboration

Owen A Ross 1 collaboration

Alison Goate 1 collaboration

Daniel H Geschwind 1 collaboration

John F Crary 1 collaboration

Yi-Ju Li 1 collaboration

Karen Nuytemans 1 collaboration

Jong Ok La 1 collaboration

Rong Jiang 1 collaboration

Susan H Slifer 1 collaboration

Shuming Sun 1 collaboration

Xiaoyi Raymond Gao 1 collaboration

Farid Rajabli 1 collaboration

Giuseppe Tosto 1 collaboration

Kara L Hamilton-Nelson 1 collaboration

Badri N Vardarajan 1 collaboration

Patrice G Whitehead 1 collaboration

Olivia K Gardner 1 collaboration

Sanjeev Sariya 1 collaboration

Richard P Mayeux 1 collaboration

Michael L Cuccaro 1 collaboration

Jeffrey M Vance 1 collaboration

Anthony J Griswold 1 collaboration

Goldie S Byrd 1 collaboration

Gary W Beecham 1 collaboration

Margaret A Pericak-Vance 1 collaboration

Carlos Cruchaga 1 collaboration

Joseph Bradley 1 collaboration

Daniel Western 1 collaboration

Ciyang Wang 1 collaboration

Eder Lucio Da Fonseca 1 collaboration

Achal Neupane 1 collaboration

Jiji Kurup 1 collaboration

NIcholas Ray 1 collaboration

Melissa Jean-Francois 1 collaboration

Priyanka Gorijala 1 collaboration

Kristy Bergmann 1 collaboration

John Budde 1 collaboration

Michael Cuccaro 1 collaboration

John Morris 1 collaboration

David Holtzman 1 collaboration

Richard Perrin 1 collaboration

Jonathan Haines 1 collaboration

Victoria Fernandez 1 collaboration

Gary Beecham 1 collaboration

Alzheimer's Disease Genetics Consortium 1 collaboration

Charles F And Joanne Knight Alzheimer's Disease Research Ce Adrc 1 collaboration

Emily Greenfest-Allen 1 collaboration

Heather Nicaretta 1 collaboration

Maureen Kirsch 1 collaboration

Youli Ren 1 collaboration

Zivadin Katanic 1 collaboration

Heather White 1 collaboration

Andrew Wilk 1 collaboration

Lauren Bass 1 collaboration

Jascha Brettschneider 1 collaboration

Luke Carter 1 collaboration

Jeffrey Cifello 1 collaboration

Wei-Hsuan Chuang 1 collaboration

Kaylyn Clark 1 collaboration

Prabhakaran Gangadharan 1 collaboration

Jacob Haut 1 collaboration

Pei-Chuan Ho 1 collaboration

Wenhwai Horng 1 collaboration

Taha Iqbal 1 collaboration

Yumi Jin 1 collaboration

Peter Keskinen 1 collaboration

Alexis Lerro Rose 1 collaboration

Michelle K Moon 1 collaboration

Joseph Manuel 1 collaboration

Liming Qu 1 collaboration

Flawless Robbins 1 collaboration

Naveensri Saravanan 1 collaboration

Jin Sha 1 collaboration

Sam Tate 1 collaboration

Laura Cantwell 1 collaboration

Jake Gardner 1 collaboration

Shin-Yi Chou 1 collaboration

Jung-Ying Tzeng 1 collaboration

William Bush 1 collaboration

Pavel Kuksa 1 collaboration