Adam S Duerfeldt

Affiliations

Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota 55414, United States.

ORCID: https://orcid.org/0000-0002-3130-9890

Publications (12)

Design and Assessment of First-Generation Heterobifunctional PPARα/STING Modulators.

ACS medicinal chemistry letters

Avec: Bo Hu , Yi Cui , Julia J Lee , Jian-Xing Ma , Adam S Duerfeldt

Clostridium difficile ClpP Homologues are Capable of Uncoupled Activity and Exhibit Different Levels of Susceptibility to Acyldepsipeptide Modulation.

ACS infectious diseases

Avec: Nathan P Lavey , Tyler Shadid , Jimmy D Ballard , Adam S Duerfeldt

Property space mapping of Pseudomonas aeruginosa permeability to small molecules.

Scientific reports

Avec: Inga V Leus , Jon W Weeks , Vincent Bonifay , Yue Shen , Liang Yang , Connor J Cooper , Dinesh Nath , Adam S Duerfeldt , Jeremy C Smith , Jerry M Parks , Valentin V Rybenkov , Helen I Zgurskaya

First-generation structure-activity relationship studies of 2,3,4,9-tetrahydro-1H-carbazol-1-amines as CpxA phosphatase inhibitors.

Bioorganic & medicinal chemistry letters

Avec: Yangxiong Li , Jessi J Gardner , Katherine R Fortney , Inga V Leus , Vincent Bonifay , Helen I Zgurskaya , Alexandre A Pletnev , Sheng Zhang , Zhong-Yin Zhang , Gordon W Gribble , Stanley M Spinola , Adam S Duerfeldt

Evolution of a 4-Benzyloxy-benzylamino Chemotype to Provide Efficacious, Potent, and Isoform Selective PPARα Agonists as Leads for Retinal Disorders.

Journal of medicinal chemistry

Avec: Xiaozheng Dou , Dinesh Nath , Henry Shin , Elmar Nurmemmedov , Philip C Bourne , Jian-Xing Ma , Adam S Duerfeldt

CpxA Phosphatase Inhibitor Activates CpxRA and Is a Potential Treatment for Uropathogenic Escherichia coli in a Murine Model of Infection.

Microbiology spectrum

Avec: Kate R Fortney , Sara N Smith , Julia J van Rensburg , Julie A Brothwell , Jessi J Gardner , Barry P Katz , Nagib Ahsan , Adam S Duerfeldt , Harry L T Mobley , Stanley M Spinola

Small-Molecule Modulation of PPARs for the Treatment of Prevalent Vascular Retinal Diseases.

International journal of molecular sciences

Avec: Xiaozheng Dou , Adam S Duerfeldt

The cGAS-STING pathway in diabetic retinopathy and age-related macular degeneration.

Future medicinal chemistry

Avec: Bo Hu , Jian-Xing Ma , Adam S Duerfeldt

Design, Synthesis, and Structure-Activity Relationships of Biaryl Anilines as Subtype-Selective PPAR-alpha Agonists.

ACS medicinal chemistry letters

Avec: Julia J Lee , Ziwei Hu , Yuhong Anna Wang , Dinesh Nath , Wentao Liang , Yi Cui , Jian-Xing Ma , Adam S Duerfeldt

Identification of ClpP Dual Isoform Disruption as an Antisporulation Strategy for Clostridioides difficile.

Journal of bacteriology

Avec: Catherine E Bishop , Tyler M Shadid , Nathan P Lavey , Megan L Kempher , Jimmy D Ballard , Adam S Duerfeldt

Structure-Uptake Relationship Studies of Oxazolidinones in Gram-Negative ESKAPE Pathogens.

Journal of medicinal chemistry

Avec: Ziwei Hu , Inga V Leus , Brinda Chandar , Bradley S Sherborne , Quentin P Avila , Valentin V Rybenkov , Helen I Zgurskaya , Adam S Duerfeldt

Guiding the Way: Traditional Medicinal Chemistry Inspiration for Rational Gram-Negative Drug Design.

Journal of medicinal chemistry

Avec: Alexis M Stoorza , Adam S Duerfeldt

Réseau de co-auteurs

Jian-Xing Ma 4 collaborations

Inga V Leus 3 collaborations

Dinesh Nath 3 collaborations

Helen I Zgurskaya 3 collaborations

Bo Hu 2 collaborations

Yi Cui 2 collaborations

Julia J Lee 2 collaborations

Nathan P Lavey 2 collaborations

Jimmy D Ballard 2 collaborations

Vincent Bonifay 2 collaborations

Valentin V Rybenkov 2 collaborations

Jessi J Gardner 2 collaborations

Stanley M Spinola 2 collaborations

Xiaozheng Dou 2 collaborations

Ziwei Hu 2 collaborations

Tyler Shadid 1 collaboration

Jon W Weeks 1 collaboration

Yue Shen 1 collaboration

Liang Yang 1 collaboration

Connor J Cooper 1 collaboration

Jeremy C Smith 1 collaboration

Jerry M Parks 1 collaboration

Yangxiong Li 1 collaboration

Katherine R Fortney 1 collaboration

Alexandre A Pletnev 1 collaboration

Sheng Zhang 1 collaboration

Zhong-Yin Zhang 1 collaboration

Gordon W Gribble 1 collaboration

Henry Shin 1 collaboration

Elmar Nurmemmedov 1 collaboration

Philip C Bourne 1 collaboration

Kate R Fortney 1 collaboration

Sara N Smith 1 collaboration

Julia J van Rensburg 1 collaboration

Julie A Brothwell 1 collaboration

Barry P Katz 1 collaboration

Nagib Ahsan 1 collaboration

Harry L T Mobley 1 collaboration

Yuhong Anna Wang 1 collaboration

Wentao Liang 1 collaboration

Catherine E Bishop 1 collaboration

Tyler M Shadid 1 collaboration

Megan L Kempher 1 collaboration

Brinda Chandar 1 collaboration

Bradley S Sherborne 1 collaboration

Quentin P Avila 1 collaboration

Alexis M Stoorza 1 collaboration