Alexander L Perryman

Affiliations

Repare Therapeutics, 7171 Frederick-Banting, Building 2, Montréal, Québec H4S 1Z9, Canada.

Publications (9)

Identification of

Journal of medicinal chemistry

Avec: Monica Bubenik , Pavel Mader , Philippe Mochirian , Fréderic Vallée , Jillian Clark , Jean-François Truchon , Alexander L Perryman , Victor Pau , Igor Kurinov , Karl E Zahn , Marie-Eve Leclaire , Robert Papp , Marie-Claude Mathieu , Martine Hamel , Nicole M Duffy , Claude Godbout , Matias Casas-Selves , Jean-Pierre Falgueyret , Prasamit S Baruah , Olivier Nicolas , Rino Stocco , Hugo Poirier , Giovanni Martino , Alexanne Bonneau Fortin , Anne Roulston , Amandine Chefson , Stéphane Dorich , Miguel St-Onge , Purvish Patel , Charles Pellerin , Stéphane Ciblat , Thomas Pinter , Francis Barabé , Majida El Bakkouri , Paranjay Parikh , Christian Gervais , Agnel Sfeir , Yael Mamane , Stephen J Morris , W Cameron Black , Frank Sicheri , Michel Gallant

Machine Learning Platform to Discover Novel Growth Inhibitors of Neisseria gonorrhoeae.

Pharmaceutical research

Avec: Janaina Cruz Pereira , Samer S Daher , Kimberley M Zorn , Matthew Sherwood , Riccardo Russo , Alexander L Perryman , Xin Wang , Madeleine J Freundlich , Sean Ekins , Joel S Freundlich

Intrabacterial Metabolism Obscures the Successful Prediction of an InhA Inhibitor of

ACS infectious diseases

Avec: Xin Wang , Alexander L Perryman , Shao-Gang Li , Steve D Paget , Thomas P Stratton , Alex Lemenze , Arthur J Olson , Sean Ekins , Pradeep Kumar , Joel S Freundlich

Bayesian Modeling and Intrabacterial Drug Metabolism Applied to Drug-Resistant

ACS infectious diseases

Avec: Jimmy S Patel , Javiera Norambuena , Hassan Al-Tameemi , Yong-Mo Ahn , Alexander L Perryman , Xin Wang , Samer S Daher , James Occi , Riccardo Russo , Steven Park , Matthew Zimmerman , Hsin-Pin Ho , David S Perlin , Véronique Dartois , Sean Ekins , Pradeep Kumar , Nancy Connell , Jeffrey M Boyd , Joel S Freundlich

Discovery of New Zika Protease and Polymerase Inhibitors through the Open Science Collaboration Project OpenZika.

Journal of chemical information and modeling

Avec: Melina Mottin , Bruna Katiele de Paula Sousa , Nathalya Cristina de Moraes Roso Mesquita , Ketllyn Irene Zagato de Oliveira , Gabriela Dias Noske , Geraldo Rodrigues Sartori , Aline de Oliveira Albuquerque , Fabio Urbina , Ana C Puhl , José Teófilo Moreira-Filho , Guilherme E Souza , Rafael V C Guido , Eugene Muratov , Bruno Junior Neves , João Hermínio Martins da Silva , Alex E Clark , Jair L Siqueira-Neto , Alexander L Perryman , Glaucius Oliva , Sean Ekins , Carolina Horta Andrade

Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306.

Journal of medicinal chemistry

Avec: Janek Szychowski , Robert Papp , Evelyne Dietrich , Bingcan Liu , Frédéric Vallée , Marie-Eve Leclaire , Jimmy Fourtounis , Giovanni Martino , Alexander L Perryman , Victor Pau , Shou Yun Yin , Pavel Mader , Anne Roulston , Jean-Francois Truchon , C Gary Marshall , Mohamed Diallo , Nicole M Duffy , Rino Stocco , Claude Godbout , Alexanne Bonneau-Fortin , Rosie Kryczka , Vivek Bhaskaran , Daniel Mao , Stephen Orlicky , Patrick Beaulieu , Pascal Turcotte , Igor Kurinov , Frank Sicheri , Yael Mamane , Michel Gallant , W Cameron Black

A diarylamine derived from anthranilic acid inhibits ZIKV replication.

Scientific reports

Avec: Suely Silva , Jacqueline Farinha Shimizu , Débora Moraes de Oliveira , Leticia Ribeiro de Assis , Cintia Bittar , Melina Mottin , Bruna Katiele de Paula Sousa , Nathalya Cristina de Moraes Roso Mesquita , Luis Octávio Regasini , Paula Rahal , Glaucius Oliva , Alexander Luke Perryman , Sean Ekins , Carolina Horta Andrade , Luiz Ricardo Goulart , Robinson Sabino-Silva , Andres Merits , Mark Harris , Ana Carolina Gomes Jardim

Pruned Machine Learning Models to Predict Aqueous Solubility.

ACS omega

Avec: Alexander L Perryman , Daigo Inoyama , Jimmy S Patel , Sean Ekins , Joel S Freundlich

Identification and Biosynthesis of an N-Glucuronide Metabolite of Camonsertib.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Robert Papp , Laird Trimble , Adrian J Fretland , Ravi Manohar , Richard Phipps , Lisbet Kvaerno , Alexander L Perryman , Gregory Reynolds , W Cameron Black

Réseau de co-auteurs

Sean Ekins 6 collaborations

Joel S Freundlich 4 collaborations

Robert Papp 3 collaborations

W Cameron Black 3 collaborations

Xin Wang 3 collaborations

Pavel Mader 2 collaborations

Victor Pau 2 collaborations

Igor Kurinov 2 collaborations

Marie-Eve Leclaire 2 collaborations

Nicole M Duffy 2 collaborations

Claude Godbout 2 collaborations

Rino Stocco 2 collaborations

Giovanni Martino 2 collaborations

Anne Roulston 2 collaborations

Yael Mamane 2 collaborations

Frank Sicheri 2 collaborations

Michel Gallant 2 collaborations

Samer S Daher 2 collaborations

Riccardo Russo 2 collaborations

Pradeep Kumar 2 collaborations

Jimmy S Patel 2 collaborations

Melina Mottin 2 collaborations

Bruna Katiele de Paula Sousa 2 collaborations

Nathalya Cristina de Moraes Roso Mesquita 2 collaborations

Glaucius Oliva 2 collaborations

Carolina Horta Andrade 2 collaborations

Monica Bubenik 1 collaboration

Philippe Mochirian 1 collaboration

Fréderic Vallée 1 collaboration

Jillian Clark 1 collaboration

Jean-François Truchon 1 collaboration

Karl E Zahn 1 collaboration

Marie-Claude Mathieu 1 collaboration

Martine Hamel 1 collaboration

Matias Casas-Selves 1 collaboration

Jean-Pierre Falgueyret 1 collaboration

Prasamit S Baruah 1 collaboration

Olivier Nicolas 1 collaboration

Hugo Poirier 1 collaboration

Alexanne Bonneau Fortin 1 collaboration

Amandine Chefson 1 collaboration

Stéphane Dorich 1 collaboration

Miguel St-Onge 1 collaboration

Purvish Patel 1 collaboration

Charles Pellerin 1 collaboration

Stéphane Ciblat 1 collaboration

Thomas Pinter 1 collaboration

Francis Barabé 1 collaboration

Majida El Bakkouri 1 collaboration

Paranjay Parikh 1 collaboration

Christian Gervais 1 collaboration

Agnel Sfeir 1 collaboration

Stephen J Morris 1 collaboration

Janaina Cruz Pereira 1 collaboration

Kimberley M Zorn 1 collaboration

Matthew Sherwood 1 collaboration

Madeleine J Freundlich 1 collaboration

Shao-Gang Li 1 collaboration

Steve D Paget 1 collaboration

Thomas P Stratton 1 collaboration

Alex Lemenze 1 collaboration

Arthur J Olson 1 collaboration

Javiera Norambuena 1 collaboration

Hassan Al-Tameemi 1 collaboration

Yong-Mo Ahn 1 collaboration

James Occi 1 collaboration

Steven Park 1 collaboration

Matthew Zimmerman 1 collaboration

Hsin-Pin Ho 1 collaboration

David S Perlin 1 collaboration

Véronique Dartois 1 collaboration

Nancy Connell 1 collaboration

Jeffrey M Boyd 1 collaboration

Ketllyn Irene Zagato de Oliveira 1 collaboration

Gabriela Dias Noske 1 collaboration

Geraldo Rodrigues Sartori 1 collaboration

Aline de Oliveira Albuquerque 1 collaboration

Fabio Urbina 1 collaboration

Ana C Puhl 1 collaboration

José Teófilo Moreira-Filho 1 collaboration

Guilherme E Souza 1 collaboration

Rafael V C Guido 1 collaboration

Eugene Muratov 1 collaboration

Bruno Junior Neves 1 collaboration

João Hermínio Martins da Silva 1 collaboration

Alex E Clark 1 collaboration

Jair L Siqueira-Neto 1 collaboration

Janek Szychowski 1 collaboration

Evelyne Dietrich 1 collaboration

Bingcan Liu 1 collaboration

Frédéric Vallée 1 collaboration

Jimmy Fourtounis 1 collaboration

Shou Yun Yin 1 collaboration

Jean-Francois Truchon 1 collaboration

C Gary Marshall 1 collaboration

Mohamed Diallo 1 collaboration

Alexanne Bonneau-Fortin 1 collaboration

Rosie Kryczka 1 collaboration

Vivek Bhaskaran 1 collaboration

Daniel Mao 1 collaboration

Stephen Orlicky 1 collaboration

Patrick Beaulieu 1 collaboration

Pascal Turcotte 1 collaboration

Suely Silva 1 collaboration

Jacqueline Farinha Shimizu 1 collaboration

Débora Moraes de Oliveira 1 collaboration

Leticia Ribeiro de Assis 1 collaboration

Cintia Bittar 1 collaboration

Luis Octávio Regasini 1 collaboration

Paula Rahal 1 collaboration

Alexander Luke Perryman 1 collaboration

Luiz Ricardo Goulart 1 collaboration

Robinson Sabino-Silva 1 collaboration

Andres Merits 1 collaboration

Mark Harris 1 collaboration

Ana Carolina Gomes Jardim 1 collaboration

Daigo Inoyama 1 collaboration

Laird Trimble 1 collaboration

Adrian J Fretland 1 collaboration

Ravi Manohar 1 collaboration

Richard Phipps 1 collaboration

Lisbet Kvaerno 1 collaboration

Gregory Reynolds 1 collaboration