Andras Kapus

Affiliations

Biochemistry Department, University of Toronto, Toronto, ON M5S 1A8, Canada; St. Michael Hospital Research Institute, Toronto, ON M5B 1W8, Canada.

Publications (22)

The Ion Transporter NKCC1 Links Cell Volume to Cell Mass Regulation by Suppressing mTORC1.

Cell reports

Avec: Wael L Demian , Avinash Persaud , Chong Jiang , Étienne Coyaud , Shixuan Liu , Andras Kapus , Ran Kafri , Brian Raught , Daniela Rotin

Augmented Parkin-dependent mitophagy underlies the hepatoprotective effect of remote ischemic conditioning used prior to hemorrhagic shock.

Mitochondrion

Avec: Avinash Naraiah Mukkala , Raluca Petrut , Rachel Goldfarb , Erika Leigh Beroncal , Chung Ho Leung , Zahra Khan , Menachem Ailenberg , Mirjana Jerkic , Ana C Andreazza , Shawn G Rhind , Marc G Jeschke , Andras Kapus , Ori D Rotstein

Nuclear Import and Export of YAP and TAZ.

Cancers

Avec: Michael Kofler , András Kapus

Myocardin-Related Transcription Factor Mediates Epithelial Fibrogenesis in Polycystic Kidney Disease.

Cells

Avec: Zsuzsanna Lichner , Mei Ding , Tarang Khare , Qinghong Dan , Raquel Benitez , Mercédesz Praszner , Xuewen Song , Rola Saleeb , Boris Hinz , York Pei , Katalin Szászi , András Kapus

Claudin-2 suppresses GEF-H1, RHOA, and MRTF, thereby impacting proliferation and profibrotic phenotype of tubular cells.

The Journal of biological chemistry

Avec: Qinghong Dan , Yixuan Shi , Razieh Rabani , Shruthi Venugopal , Jenny Xiao , Shaista Anwer , Mei Ding , Pam Speight , Wanling Pan , R Todd Alexander , András Kapus , Katalin Szászi

Nuclear Factor (Erythroid-Derived 2)-Like 2 Regulates the Hepatoprotective Effects of Remote Ischemic Conditioning in Hemorrhagic Shock.

Antioxidants & redox signaling

Avec: Chung Ho Leung , Christopher A Caldarone , Rui Guan , Xiao-Yan Wen , Menachem Ailenberg , Andras Kapus , Katalin Szaszi , Ori D Rotstein

Kindlin-2 Mediates Mechanical Activation of Cardiac Myofibroblasts.

Cells

Avec: Elena Godbout , Dong Ok Son , Stephanie Hume , Stellar Boo , Vincent Sarrazy , Sophie Clément , Andras Kapus , Bernhard Wehrle-Haller , Leena Bruckner-Tuderman , Cristina Has , Boris Hinz

Improved SARS-CoV-2 PCR detection and genotyping with double-bubble primers.

BioTechniques

Avec: Menachem Ailenberg , Andras Kapus , Ori D Rotstein

Nucleocytoplasmic Shuttling of the Mechanosensitive Transcription Factors MRTF and YAP /TAZ.

Methods in molecular biology (Clifton, N.J.)

Avec: Michael Kofler , András Kapus

Hemorrhagic Shock/Resuscitation Reduces the M2 Phenotype of Alveolar Macrophages: A Potential Mechanism Contributing to Increased LPS-Induced Lung Injury.

Shock (Augusta, Ga.)

Avec: Dana Safavian , Chung Ho Leung , Andras Kapus , Menachem Ailenberg , Katalin Szaszi , Ravi Shani , Caterina Di Ciano-Oliveira , Magar Ghazarian , Ori Rotstein

Advancing Discovery Research in Nephrology in Canada: A Conference Report From the 2021 Molecules and Mechanisms Mediating Kidney Health and Disease (M3K) Scientific Meeting and Investigator Summit.

Canadian journal of kidney health and disease

Avec: Dylan Burger , Amira Abdelrasoul , R Todd Alexander , Barbara Ballermann , Darren Bridgewater , John S D Chan , Joanna Cunanan , Andrey V Cybulsky , Casimiro Gerarduzzi , Lakshman Gunaratnam , Sunny Hartwig , Andras Kapus , Christopher R J Kennedy , Caroline Lamarche , Robert L Myette , Ifeanyi Kennedy Nmecha , Leanne Stalker , Katalin Szaszi , Elena Torban , Shao Ling Zhang , Tomoko Takano

Profibrotic epithelial phenotype: a central role for MRTF and TAZ.

Scientific reports

Avec: Janne Folke Bialik , Mei Ding , Pam Speight , Qinghong Dan , Maria Zena Miranda , Caterina Di Ciano-Oliveira , Michael M Kofler , Ori D Rotstein , Stine F Pedersen , Katalin Szászi , András Kapus

Sunitinib induces early histomolecular changes in a subset of renal cancer cells that contribute to resistance.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: Zsuzsanna Lichner , Rola Saleeb , Henriett Butz , Qiang Ding , Roy Nofech-Mozes , Sara Riad , Mina Farag , Amir K Varkouhi , Claudia C Dos Santos , András Kapus , George M Yousef

Myocardin-related transcription factor and serum response factor regulate cilium turnover by both transcriptional and local mechanisms.

iScience

Avec: Pam Speight , Matthew Rozycki , Shruthi Venugopal , Katalin Szászi , Michael Kofler , András Kapus

ACTIVATION OF THE MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN (MAVS) FOLLOWING LIVER ISCHEMIA/REPERFUSION AND ITS EFFECT ON INFLAMMATION AND INJURY.

Shock (Augusta, Ga.)

Avec: Menachem Ailenberg , Andras Kapus , Chung Ho Leung , Katalin Szaszi , Philip Williams , Caterina diCiano-Oliveira , John C Marshall , Ori D Rotstein

Avoidance of apoptotic death via a hyperploid salvage survival pathway after platinum treatment in high grade serous carcinoma cell line models.

Oncotarget

Avec: Tony Yeung , Oliver Fung , Mikhail Bashkurov , Arian Khandani , Omar Subedar , Alexandra Wudwud , Patricia Shaw , Blaise Clarke , John Bartlett , Robert Rottapel , Andras Kapus

DDR1 associates with TRPV4 in cell-matrix adhesions to enable calcium-regulated myosin activity and collagen compaction.

Journal of cellular physiology

Avec: Andrew Y Wang , Nuno M Coelho , Pamma D Arora , Yongqiang Wang , Denise Eymael , Chenfan Ji , Qin Wang , Wilson Lee , Jessica Xu , Andras Kapus , Karina M M Carneiro , Christopher A McCulloch

MRTF: Basic Biology and Role in Kidney Disease.

International journal of molecular sciences

Avec: Maria Zena Miranda , Zsuzsanna Lichner , Katalin Szászi , András Kapus

Endothelial ACKR1 is induced by neutrophil contact and down-regulated by secretion in extracellular vesicles.

Frontiers in immunology

Avec: Xinying Guo , Negar Khosraviani , Sneha Raju , Joshya Singh , Nikki Zamani Farahani , Madlene Abramian , Victor J Torres , Kathryn L Howe , Jason E Fish , Andras Kapus , Warren L Lee

Therapeutic Effects of Mesenchymal Stromal Cells Require Mitochondrial Transfer and Quality Control.

International journal of molecular sciences

Avec: Avinash Naraiah Mukkala , Mirjana Jerkic , Zahra Khan , Katalin Szaszi , Andras Kapus , Ori Rotstein

Regulation of the RhoA exchange factor GEF-H1 by pro-fibrotic stimuli through a positive feedback loop involving RhoA, MRTF and Sp1.

American journal of physiology. Cell physiology

Avec: Shruthi Venugopal , Qinghong Dan , Veroni S Sri Theivakadadcham , Brian Rai-Ling Wu , Michael Kofler , Matthew D Layne , Kim A Connelly , Mark F Rzepka , Mark K Friedberg , Andras Kapus , Katalin Szaszi

Inhibition of MRTF-A Ameliorates Pathological Remodeling of the Pressure-loaded Right Ventricle.

American journal of respiratory cell and molecular biology

Avec: Mark F Rzepka , Sonja Raschzok , Xavier A Lee , Kana Yazaki , John Dauz , Mei Sun , Theo Meister , Linda Nghiem , Golam Kabir , Jean-Francois Desjardins , Wolfgang M Kuebler , Andras Kapus , Kim A Connelly , Mark K Friedberg

Réseau de co-auteurs

András Kapus 8 collaborations

Katalin Szaszi 6 collaborations

Menachem Ailenberg 5 collaborations

Ori D Rotstein 5 collaborations

Katalin Szászi 5 collaborations

Chung Ho Leung 4 collaborations

Michael Kofler 4 collaborations

Qinghong Dan 4 collaborations

Zsuzsanna Lichner 3 collaborations

Mei Ding 3 collaborations

Shruthi Venugopal 3 collaborations

Pam Speight 3 collaborations

Avinash Naraiah Mukkala 2 collaborations

Zahra Khan 2 collaborations

Mirjana Jerkic 2 collaborations

Rola Saleeb 2 collaborations

Boris Hinz 2 collaborations

R Todd Alexander 2 collaborations

Caterina Di Ciano-Oliveira 2 collaborations

Ori Rotstein 2 collaborations

Maria Zena Miranda 2 collaborations

Kim A Connelly 2 collaborations

Mark F Rzepka 2 collaborations

Mark K Friedberg 2 collaborations

Wael L Demian 1 collaboration

Avinash Persaud 1 collaboration

Chong Jiang 1 collaboration

Étienne Coyaud 1 collaboration

Shixuan Liu 1 collaboration

Ran Kafri 1 collaboration

Brian Raught 1 collaboration

Daniela Rotin 1 collaboration

Raluca Petrut 1 collaboration

Rachel Goldfarb 1 collaboration

Erika Leigh Beroncal 1 collaboration

Ana C Andreazza 1 collaboration

Shawn G Rhind 1 collaboration

Marc G Jeschke 1 collaboration

Tarang Khare 1 collaboration

Raquel Benitez 1 collaboration

Mercédesz Praszner 1 collaboration

Xuewen Song 1 collaboration

York Pei 1 collaboration

Yixuan Shi 1 collaboration

Razieh Rabani 1 collaboration

Jenny Xiao 1 collaboration

Shaista Anwer 1 collaboration

Wanling Pan 1 collaboration

Christopher A Caldarone 1 collaboration

Rui Guan 1 collaboration

Xiao-Yan Wen 1 collaboration

Elena Godbout 1 collaboration

Dong Ok Son 1 collaboration

Stephanie Hume 1 collaboration

Stellar Boo 1 collaboration

Vincent Sarrazy 1 collaboration

Sophie Clément 1 collaboration

Bernhard Wehrle-Haller 1 collaboration

Leena Bruckner-Tuderman 1 collaboration

Cristina Has 1 collaboration

Dana Safavian 1 collaboration

Ravi Shani 1 collaboration

Magar Ghazarian 1 collaboration

Dylan Burger 1 collaboration

Amira Abdelrasoul 1 collaboration

Barbara Ballermann 1 collaboration

Darren Bridgewater 1 collaboration

John S D Chan 1 collaboration

Joanna Cunanan 1 collaboration

Andrey V Cybulsky 1 collaboration

Casimiro Gerarduzzi 1 collaboration

Lakshman Gunaratnam 1 collaboration

Sunny Hartwig 1 collaboration

Christopher R J Kennedy 1 collaboration

Caroline Lamarche 1 collaboration

Robert L Myette 1 collaboration

Ifeanyi Kennedy Nmecha 1 collaboration

Leanne Stalker 1 collaboration

Elena Torban 1 collaboration

Shao Ling Zhang 1 collaboration

Tomoko Takano 1 collaboration

Janne Folke Bialik 1 collaboration

Michael M Kofler 1 collaboration

Stine F Pedersen 1 collaboration

Henriett Butz 1 collaboration

Qiang Ding 1 collaboration

Roy Nofech-Mozes 1 collaboration

Sara Riad 1 collaboration

Mina Farag 1 collaboration

Amir K Varkouhi 1 collaboration

Claudia C Dos Santos 1 collaboration

George M Yousef 1 collaboration

Matthew Rozycki 1 collaboration

Philip Williams 1 collaboration

Caterina diCiano-Oliveira 1 collaboration

John C Marshall 1 collaboration

Tony Yeung 1 collaboration

Oliver Fung 1 collaboration

Mikhail Bashkurov 1 collaboration

Arian Khandani 1 collaboration

Omar Subedar 1 collaboration

Alexandra Wudwud 1 collaboration

Patricia Shaw 1 collaboration

Blaise Clarke 1 collaboration

John Bartlett 1 collaboration

Robert Rottapel 1 collaboration

Andrew Y Wang 1 collaboration

Nuno M Coelho 1 collaboration

Pamma D Arora 1 collaboration

Yongqiang Wang 1 collaboration

Denise Eymael 1 collaboration

Chenfan Ji 1 collaboration

Qin Wang 1 collaboration

Wilson Lee 1 collaboration

Jessica Xu 1 collaboration

Karina M M Carneiro 1 collaboration

Christopher A McCulloch 1 collaboration

Xinying Guo 1 collaboration

Negar Khosraviani 1 collaboration

Sneha Raju 1 collaboration

Joshya Singh 1 collaboration

Nikki Zamani Farahani 1 collaboration

Madlene Abramian 1 collaboration

Victor J Torres 1 collaboration

Kathryn L Howe 1 collaboration

Jason E Fish 1 collaboration

Warren L Lee 1 collaboration

Veroni S Sri Theivakadadcham 1 collaboration

Brian Rai-Ling Wu 1 collaboration

Matthew D Layne 1 collaboration

Sonja Raschzok 1 collaboration

Xavier A Lee 1 collaboration

Kana Yazaki 1 collaboration

John Dauz 1 collaboration

Mei Sun 1 collaboration

Theo Meister 1 collaboration

Linda Nghiem 1 collaboration

Golam Kabir 1 collaboration

Jean-Francois Desjardins 1 collaboration

Wolfgang M Kuebler 1 collaboration