Andrea Spallarossa

Affiliations

Department of Pharmacy, University of Genova, Viale Benedetto XV, 3, 16132 Genova, Italy.

Publications (29)

Regioselective Synthesis, Structural Characterization, and Antiproliferative Activity of Novel Tetra-Substituted Phenylaminopyrazole Derivatives.

Molecules (Basel, Switzerland)

Avec: Matteo Lusardi , Aldo Profumo , Chiara Rotolo , Erika Iervasi , Camillo Rosano , Andrea Spallarossa , Marco Ponassi

Insights into the Pharmacological Activity of the Imidazo-Pyrazole Scaffold.

ChemMedChem

Avec: Andrea Spallarossa , Federica Rapetti , Maria Grazia Signorello , Camillo Rosano , Erika Iervasi , Marco Ponassi , Chiara Brullo

Microbiological Screening of 5-Functionalized Pyrazoles for the Future Development of Optimized Pyrazole-Based Delivery Systems.

Pharmaceutics

Avec: Chiara Brullo , Debora Caviglia , Andrea Spallarossa , Silvana Alfei , Scott G Franzblau , Bruno Tasso , Anna Maria Schito

New Pyrazolyl Thioureas Active against the

Pharmaceuticals (Basel, Switzerland)

Avec: Anna Maria Schito , Debora Caviglia , Susanna Penco , Andrea Spallarossa , Elena Cichero , Bruno Tasso , Chiara Brullo

Investigations of Antioxidant and Anti-Cancer Activities of 5-Aminopyrazole Derivatives.

Molecules (Basel, Switzerland)

Avec: Federica Rapetti , Andrea Spallarossa , Eleonora Russo , Debora Caviglia , Carla Villa , Bruno Tasso , Maria Grazia Signorello , Camillo Rosano , Erika Iervasi , Marco Ponassi , Chiara Brullo

Synthesis, functional proteomics and biological evaluation of new 5-pyrazolyl ureas as potential anti-angiogenic compounds.

European journal of medicinal chemistry

Avec: Elva Morretta , Adama Sidibè , Andrea Spallarossa , Antonello Petrella , Elda Meta , Olga Bruno , Maria Chiara Monti , Chiara Brullo

Novel insights on the molecular mechanism of action of the anti-angiogenic pyrazolyl-urea GeGe-3 by functional proteomics.

Bioorganic chemistry

Avec: Elva Morretta , Raffaella Belvedere , Antonello Petrella , Andrea Spallarossa , Federica Rapetti , Olga Bruno , Chiara Brullo , Maria Chiara Monti

The Development of BTK Inhibitors: A Five-Year Update.

Molecules (Basel, Switzerland)

Avec: Bruno Tasso , Andrea Spallarossa , Eleonora Russo , Chiara Brullo

Antimalarial Activity of Tri- and Tetra-Substituted Anilino Pyrazoles.

Molecules (Basel, Switzerland)

Avec: Matteo Lusardi , Nicoletta Basilico , Chiara Rotolo , Silvia Parapini , Andrea Spallarossa

Amino-Pyrazoles in Medicinal Chemistry: A Review.

International journal of molecular sciences

Avec: Matteo Lusardi , Andrea Spallarossa , Chiara Brullo

Novel 5-aminopyrazoles endowed with anti-angiogenetic properties: Design, synthesis and biological evaluation.

European journal of medicinal chemistry

Avec: Matteo Lusardi , Bernhard Wehrle-Haller , Adama Sidibe , Marco Ponassi , Erika Iervasi , Camillo Rosano , Chiara Brullo , Andrea Spallarossa

Structure-Activity Relationship Studies on Highly Functionalized Pyrazole Hydrazones and Amides as Antiproliferative and Antioxidant Agents.

International journal of molecular sciences

Avec: Matteo Lusardi , Maria Grazia Signorello , Eleonora Russo , Debora Caviglia , Marco Ponassi , Erika Iervasi , Camillo Rosano , Chiara Brullo , Andrea Spallarossa

Btk Inhibitors: A Medicinal Chemistry and Drug Delivery Perspective.

International journal of molecular sciences

Avec: Chiara Brullo , Carla Villa , Bruno Tasso , Eleonora Russo , Andrea Spallarossa

Successful Dendrimer and Liposome-Based Strategies to Solubilize an Antiproliferative Pyrazole Otherwise Not Clinically Applicable.

Nanomaterials (Basel, Switzerland)

Avec: Silvana Alfei , Andrea Spallarossa , Matteo Lusardi , Guendalina Zuccari

One-Pot Synthesis and Antiproliferative Activity of Highly Functionalized Pyrazole Derivatives.

ChemMedChem

Avec: Matteo Lusardi , Chiara Rotolo , Marco Ponassi , Erika Iervasi , Camillo Rosano , Andrea Spallarossa

The Development of FAK Inhibitors: A Five-Year Update.

International journal of molecular sciences

Avec: Andrea Spallarossa , Bruno Tasso , Eleonora Russo , Carla Villa , Chiara Brullo

Nanotechnology for Pediatric Retinoblastoma Therapy.

Pharmaceuticals (Basel, Switzerland)

Avec: Eleonora Russo , Andrea Spallarossa , Bruno Tasso , Carla Villa , Chiara Brullo

Indole Antitumor Agents in Nanotechnology Formulations: An Overview.

Pharmaceutics

Avec: Eleonora Russo , Carola Grondona , Chiara Brullo , Andrea Spallarossa , Carla Villa , Bruno Tasso

Novel tetrasubstituted 5-Arylamino pyrazoles able to interfere with angiogenesis and Ca

European journal of medicinal chemistry

Avec: Matteo Lusardi , Raffaella Belvedere , Antonello Petrella , Erika Iervasi , Marco Ponassi , Chiara Brullo , Andrea Spallarossa

Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel-Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7.

Journal of medicinal chemistry

Avec: Vittoria Zoppi , Scott J Hughes , Chiara Maniaci , Andrea Testa , Teresa Gmaschitz , Corinna Wieshofer , Manfred Koegl , Kristin M Riching , Danette L Daniels , Andrea Spallarossa , Alessio Ciulli

Molecules (Basel, Switzerland)

Avec: Andrea Spallarossa , Matteo Lusardi , Chiara Caneva , Aldo Profumo , Camillo Rosano , Marco Ponassi

Nanotechnology of Tyrosine Kinase Inhibitors in Cancer Therapy: A Perspective.

International journal of molecular sciences

Avec: Eleonora Russo , Andrea Spallarossa , Bruno Tasso , Carla Villa , Chiara Brullo

Valorization and Potential Antimicrobial Use of Olive Mill Wastewater (OMW) from Italian Olive Oil Production.

Antioxidants (Basel, Switzerland)

Avec: Eleonora Russo , Andrea Spallarossa , Antonio Comite , Marcello Pagliero , Patrizia Guida , Vittorio Belotti , Debora Caviglia , Anna Maria Schito

Potent and Broad-Spectrum Bactericidal Activity of a Nanotechnologically Manipulated Novel Pyrazole.

Biomedicines

Avec: Silvana Alfei , Debora Caviglia , Alessia Zorzoli , Danilo Marimpietri , Andrea Spallarossa , Matteo Lusardi , Guendalina Zuccari , Anna Maria Schito

Cyclic diacyl thioureas enhance activity of corrector Lumacaftor on F508del-CFTR.

ChemMedChem

Avec: Andrea Spallarossa , Nicoletta Pedemonte , Emanuela Pesce , Enrico Millo , Elena Cichero , Camillo Rosano , Matteo Lusardi , Erika Iervasi , Marco Ponassi

Mono- and di-acylated imidazolidine-2-thione derivatives: synthesis, cytotoxicity evaluation and computational studies.

Molecular diversity

Avec: Anna Scarsi , Marco Ponassi , Chiara Brullo , Camillo Rosano , Andrea Spallarossa

Targeting USP-7 by a Novel Fluorinated 5-Pyrazolyl-Urea Derivative.

International journal of molecular sciences

Avec: Elva Morretta , Chiara Brullo , Raffaella Belvedere , Antonello Petrella , Andrea Spallarossa , Maria Chiara Monti

A Proteomics Approach Identifies RREB1 as a Crucial Molecular Target of Imidazo-Pyrazole Treatment in SKMEL-28 Melanoma Cells.

International journal of molecular sciences

Avec: Erika Iervasi , Gabriela Coronel Vargas , Tiziana Bachetti , Kateryna Tkachenko , Andrea Spallarossa , Chiara Brullo , Camillo Rosano , Sonia Carta , Paola Barboro , Aldo Profumo , Marco Ponassi

PDE4D: A Multipurpose Pharmacological Target.

International journal of molecular sciences

Avec: Matteo Lusardi , Federica Rapetti , Andrea Spallarossa , Chiara Brullo

Réseau de co-auteurs

Chiara Brullo 20 collaborations

Matteo Lusardi 12 collaborations

Marco Ponassi 11 collaborations

Camillo Rosano 10 collaborations

Erika Iervasi 9 collaborations

Bruno Tasso 9 collaborations

Eleonora Russo 9 collaborations

Debora Caviglia 6 collaborations

Carla Villa 6 collaborations

Federica Rapetti 4 collaborations

Anna Maria Schito 4 collaborations

Antonello Petrella 4 collaborations

Aldo Profumo 3 collaborations

Chiara Rotolo 3 collaborations

Maria Grazia Signorello 3 collaborations

Silvana Alfei 3 collaborations

Elva Morretta 3 collaborations

Maria Chiara Monti 3 collaborations

Raffaella Belvedere 3 collaborations

Elena Cichero 2 collaborations

Olga Bruno 2 collaborations

Guendalina Zuccari 2 collaborations

Scott G Franzblau 1 collaboration

Susanna Penco 1 collaboration

Adama Sidibè 1 collaboration

Elda Meta 1 collaboration

Nicoletta Basilico 1 collaboration

Silvia Parapini 1 collaboration

Bernhard Wehrle-Haller 1 collaboration

Adama Sidibe 1 collaboration

Carola Grondona 1 collaboration

Vittoria Zoppi 1 collaboration

Scott J Hughes 1 collaboration

Chiara Maniaci 1 collaboration

Andrea Testa 1 collaboration

Teresa Gmaschitz 1 collaboration

Corinna Wieshofer 1 collaboration

Manfred Koegl 1 collaboration

Kristin M Riching 1 collaboration

Danette L Daniels 1 collaboration

Alessio Ciulli 1 collaboration

Chiara Caneva 1 collaboration

Antonio Comite 1 collaboration

Marcello Pagliero 1 collaboration

Patrizia Guida 1 collaboration

Vittorio Belotti 1 collaboration

Alessia Zorzoli 1 collaboration

Danilo Marimpietri 1 collaboration

Nicoletta Pedemonte 1 collaboration

Emanuela Pesce 1 collaboration

Enrico Millo 1 collaboration

Anna Scarsi 1 collaboration

Gabriela Coronel Vargas 1 collaboration

Tiziana Bachetti 1 collaboration

Kateryna Tkachenko 1 collaboration

Sonia Carta 1 collaboration

Paola Barboro 1 collaboration