B Readhead

Affiliations

Department of Genetics and Genomic Sciences, Institute of Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Publications (32)

miR155 regulation of behavior, neuropathology, and cortical transcriptomics in Alzheimer's disease.

Acta neuropathologica

Avec: Ben Readhead , Jean-Vianney Haure-Mirande , Diego Mastroeni , Mickael Audrain , Tomas Fanutza , Soong H Kim , Robert D Blitzer , Sam Gandy , Joel T Dudley , Michelle E Ehrlich

Systematic Analysis of Environmental Chemicals That Dysregulate Critical Period Plasticity-Related Gene Expression Reveals Common Pathways That Mimic Immune Response to Pathogen.

Neural plasticity

Avec: Milo R Smith , Priscilla Yevoo , Masato Sadahiro , Ben Readhead , Brian Kidd , Joel T Dudley , Hirofumi Morishita

Viral activation and ecological restructuring characterize a microbiome axis of spaceflight-associated immune activation.

Research square

Avec: Braden T Tierney , JangKeun Kim , Eliah G Overbey , Krista A Ryon , Jonathan Foox , Maria Sierra , Chandrima Bhattacharya , Namita Damle , Deena Najjar , Jiwoon Park , Sebastian Garcia Medina , Nadia Houerbi , Cem Meydan , Jeremy Wain Hershberg , Jake Qiu , Ashley Kleinman , Gabe Al Ghalith , Matthew MacKay , Evan E Afshin , Raja Dhir , Joseph Borg , Christine Gatt , Nicholas Brereton , Ben Readhead , Semir Beyaz , Kasthuri J Venkateswaran , Kelly Blease , Juan Moreno , Andrew Boddicker , Junhua Zhao , Bryan Lajoie , Ryan T Scott , Andrew Altomare , Semyon Kruglyak , Shawn Levy , George Church , Christopher E Mason

Reduced

bioRxiv : the preprint server for biology

Avec: Camila de Ávila , Crystal Suazo , Jennifer Nolz , J Nicholas Cochran , Qi Wang , Ramon Velazquez , Eric Dammer , Benjamin Readhead , Diego Mastroeni

Alterations in innate immunity and epithelial cell differentiation are the molecular pillars of hidradenitis suppurativa.

Journal of the European Academy of Dermatology and Venereology : JEADV

Avec: C C Zouboulis , A Nogueira da Costa , E Makrantonaki , X X Hou , D Almansouri , J T Dudley , H Edwards , B Readhead , O Balthasar , G B E Jemec , N G Bonitsis , G Nikolakis , D Trebing , K C Zouboulis , A M Hossini

Longitudinal data in peripheral blood confirm that PM20D1 is a quantitative trait locus (QTL) for Alzheimer's disease and implicate its dynamic role in disease progression.

Clinical epigenetics

Avec: Qi Wang , Yinghua Chen , Benjamin Readhead , Kewei Chen , Yi Su , Eric M Reiman , Joel T Dudley

Beneficial effects of physical exercise and an orally active mGluR2/3 antagonist pro-drug on neurogenesis and behavior in an Alzheimer's amyloidosis model.

Frontiers in dementia

Avec: Georgina Perez Garcia , Mesude Bicak , Jacqueline Buros , Jean-Vianney Haure-Mirande , Gissel M Perez , Alena Otero-Pagan , Miguel A Gama Sosa , Rita De Gasperi , Mary Sano , Fred H Gage , Carrolee Barlow , Joel T Dudley , Benjamin S Glicksberg , Yanzhuang Wang , Benjamin Readhead , Michelle E Ehrlich , Gregory A Elder , Sam Gandy

Heparin treatment is associated with a delayed diagnosis of Alzheimer's dementia in electronic health records from two large United States health systems.

Molecular psychiatry

Avec: Benjamin Readhead , Eyal Klang , Undina Gisladottir , Maxence Vandromme , Li Li , Yakeel T Quiroz , Joseph F Arboleda-Velasquez , Joel T Dudley , Nicholas P Tatonetti , Benjamin S Glicksberg , Eric M Reiman

Transcriptomic Network Interactions in Human Skin Treated with Topical Glucocorticoid Clobetasol Propionate.

The Journal of investigative dermatology

Avec: Loukia N Lili , Anna Klopot , Benjamin Readhead , Gleb Baida , Joel T Dudley , Irina Budunova

Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits.

BMC medical genomics

Avec: Benjamin S Glicksberg , Letizia Amadori , Nicholas K Akers , Katyayani Sukhavasi , Oscar Franzén , Li Li , Gillian M Belbin , Kristin L Ayers , Khader Shameer , Marcus A Badgeley , Kipp W Johnson , Ben Readhead , Bruce J Darrow , Eimear E Kenny , Christer Betsholtz , Raili Ermel , Josefin Skogsberg , Arno Ruusalepp , Eric E Schadt , Joel T Dudley , Hongxia Ren , Jason C Kovacic , Chiara Giannarelli , Shuyu D Li , Johan L M Björkegren , Rong Chen

Systems Pharmacology Identifies an Arterial Wall Regulatory Gene Network Mediating Coronary Artery Disease Side Effects of Antiretroviral Therapy.

Circulation. Genomic and precision medicine

Avec: Itziar Frades , Ben Readhead , Letizia Amadori , Simon Koplev , Husain A Talukdar , Heidi M Crane , Paul K Crane , Jason C Kovacic , Joel T Dudley , Chiara Giannarelli , Johan L M Björkegren , Inga Peter

Critical period plasticity-related transcriptional aberrations in schizophrenia and bipolar disorder.

Schizophrenia research

Avec: Milo R Smith , Ben Readhead , Joel T Dudley , Hirofumi Morishita

Deep learning-based brain transcriptomic signatures associated with the neuropathological and clinical severity of Alzheimer's disease.

Brain communications

Avec: Qi Wang , Kewei Chen , Yi Su , Eric M Reiman , Joel T Dudley , Benjamin Readhead

REDD1 (regulated in development and DNA damage 1) modulates the glucocorticoid receptor function in keratinocytes.

Experimental dermatology

Avec: D A Chudakova , D Trubetskoy , G Baida , P Bhalla , B Readhead , I Budunova

BCI-838, an orally active mGluR2/3 receptor antagonist pro-drug, rescues learning behavior deficits in the PS19 MAPT

Neuroscience letters

Avec: Georgina Perez-Garcia , Mesude Bicak , Jean-Vianney Haure-Mirande , Gissel M Perez , Alena Otero-Pagan , Miguel A Gama Sosa , Rita De Gasperi , Mary Sano , Carrolee Barlow , Fred H Gage , Benjamin Readhead , Michelle E Ehrlich , Sam Gandy , Gregory A Elder

Reduced PIN1 expression in neocortical and limbic brain regions in female Alzheimer's patients correlates with cognitive and neuropathological phenotypes.

Neurobiology of aging

Avec: Camila de Ávila , Crystal Suazo , Jennifer Nolz , J Nicholas Cochran , Qi Wang , Ramon Velazquez , Eric Dammer , Benjamin Readhead , Diego Mastroeni

Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits.

Nature communications

Avec: Wen Zhang , Georgios Voloudakis , Veera M Rajagopal , Ben Readhead , Joel T Dudley , Eric E Schadt , Johan L M Björkegren , Yungil Kim , John F Fullard , Gabriel E Hoffman , Panos Roussos

PI3K inhibitors protect against glucocorticoid-induced skin atrophy.

EBioMedicine

Avec: Shivani Agarwal , Salida Mirzoeva , Ben Readhead , Joel T Dudley , Irina Budunova

Correction: Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden.

Molecular psychiatry

Avec: Jean-Vianney Haure-Mirande , Minghui Wang , Mickael Audrain , Tomas Fanutza , Soong Ho Kim , Szilvia Heja , Ben Readhead , Joel T Dudley , Robert D Blitzer , Eric E Schadt , Bin Zhang , Sam Gandy , Michelle E Ehrlich

Do infections have a role in the pathogenesis of Alzheimer disease?

Nature reviews. Neurology

Avec: Ruth F Itzhaki , Todd E Golde , Michael T Heneka , Ben Readhead

A Novel Approach to Safer Glucocorticoid Receptor-Targeted Anti-lymphoma Therapy via REDD1 (Regulated in Development and DNA Damage 1) Inhibition.

Molecular cancer therapeutics

Avec: Ekaterina A Lesovaya , Alena V Savinkova , Olga V Morozova , Evgeniya S Lylova , Ekaterina M Zhidkova , Evgeny P Kulikov , Kirill I Kirsanov , Anna Klopot , Gleb Baida , Marianna G Yakubovskaya , Leo I Gordon , Ben Readhead , Joel T Dudley , Irina Budunova

Sexual dimorphism in atrophic effects of topical glucocorticoids is driven by differential regulation of atrophogene REDD1 in male and female skin.

Oncotarget

Avec: Gleb Baida , Shivani Agarwal , Ben Readhead , Joel T Dudley , Irina Budunova

The viral hypothesis: how herpesviruses may contribute to Alzheimer's disease.

Molecular psychiatry

Avec: Michael Wainberg , Tain Luquez , David M Koelle , Ben Readhead , Christine Johnston , Martin Darvas , Cory C Funk

Repositioning of a novel GABA-B receptor agonist, AZD3355 (Lesogaberan), for the treatment of non-alcoholic steatohepatitis.

Scientific reports

Avec: Dipankar Bhattacharya , Christine Becker , Benjamin Readhead , Nicolas Goossens , Jacqueline Novik , Maria Isabel Fiel , Leslie P Cousens , Björn Magnusson , Anna Backmark , Ryan Hicks , Joel T Dudley , Scott L Friedman

Modeling of mitochondrial genetic polymorphisms reveals induction of heteroplasmy by pleiotropic disease locus 10398A>G.

Scientific reports

Avec: Molly Smullen , Meagan N Olson , Liam F Murray , Madhusoodhanan Suresh , Guang Yan , Pepper Dawes , Nathaniel J Barton , Jivanna N Mason , Yucheng Zhang , Aria A Fernandez-Fontaine , George M Church , Diego Mastroeni , Qi Wang , Elaine T Lim , Yingleong Chan , Benjamin Readhead

Quantitative assessment of multiple pathogen exposure and immune dynamics at scale.

Microbiology spectrum

Avec: Lusheng Song , Femina Rauf , Ching-Wen Hou , Ji Qiu , Vel Murugan , Yunro Chung , Huafang Lai , Deborah Adam , D Mitchell Magee , Guillermo Trivino Soto , Milene Peterson , Karen S Anderson , Stephen G Rice , Benjamin Readhead , Jin G Park , Joshua LaBaer

Correction to: Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits.

BMC medical genomics

Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans.

BMC genetics

Avec: Ke Xu , Roman Kosoy , Khader Shameer , Sudhir Kumar , Li Liu , Ben Readhead , Gillian M Belbin , Hao-Chih Lee , Rong Chen , Joel T Dudley

Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden.

Molecular psychiatry

Mapping of SARS-CoV-2 Brain Invasion and Histopathology in COVID-19 Disease.

medRxiv : the preprint server for health sciences

Avec: Geidy E Serrano , Jessica E Walker , Richard Arce , Michael J Glass , Daisy Vargas , Lucia I Sue , Anthony J Intorcia , Courtney M Nelson , Javon Oliver , Jaclyn Papa , Aryck Russell , Katsuko E Suszczewicz , Claryssa I Borja , Christine Belden , Danielle Goldfarb , David Shprecher , Alireza Atri , Charles H Adler , Holly A Shill , Erika Driver-Dunckley , Shyamal H Mehta , Benjamin Readhead , Matthew J Huentelman , Joseph L Peters , Ellie Alevritis , Christian Bimi , Joseph P Mizgerd , Eric M Reiman , Thomas J Montine , Marc Desforges , James L Zehnder , Malaya K Sahoo , Haiyu Zhang , Daniel Solis , Benjamin A Pinsky , Michael Deture , Dennis W Dickson , Thomas G Beach

Systems modeling of metabolic dysregulation in neurodegenerative diseases.

Current opinion in pharmacology

Avec: Priyanka Baloni , Cory C Funk , Ben Readhead , Nathan D Price

Reliable multiplex generation of pooled induced pluripotent stem cells.

Cell reports methods

Avec: Molly Smullen , Meagan N Olson , Julia M Reichert , Pepper Dawes , Liam F Murray , Christina E Baer , Qi Wang , Benjamin Readhead , George M Church , Elaine T Lim , Yingleong Chan

Réseau de co-auteurs

Joel T Dudley 19 collaborations

Ben Readhead 17 collaborations

Benjamin Readhead 13 collaborations

Qi Wang 6 collaborations

Jean-Vianney Haure-Mirande 5 collaborations

Sam Gandy 5 collaborations

Michelle E Ehrlich 5 collaborations

Eric E Schadt 5 collaborations

Diego Mastroeni 4 collaborations

Eric M Reiman 4 collaborations

Benjamin S Glicksberg 4 collaborations

Irina Budunova 4 collaborations

Johan L M Björkegren 4 collaborations

Mickael Audrain 3 collaborations

Tomas Fanutza 3 collaborations

Robert D Blitzer 3 collaborations

Li Li 3 collaborations

Gleb Baida 3 collaborations

Letizia Amadori 3 collaborations

Gillian M Belbin 3 collaborations

Khader Shameer 3 collaborations

Jason C Kovacic 3 collaborations

Chiara Giannarelli 3 collaborations

Rong Chen 3 collaborations

Milo R Smith 2 collaborations

Hirofumi Morishita 2 collaborations

Camila de Ávila 2 collaborations

Crystal Suazo 2 collaborations

Jennifer Nolz 2 collaborations

J Nicholas Cochran 2 collaborations

Ramon Velazquez 2 collaborations

Eric Dammer 2 collaborations

Kewei Chen 2 collaborations

Yi Su 2 collaborations

Mesude Bicak 2 collaborations

Gissel M Perez 2 collaborations

Alena Otero-Pagan 2 collaborations

Miguel A Gama Sosa 2 collaborations

Rita De Gasperi 2 collaborations

Mary Sano 2 collaborations

Fred H Gage 2 collaborations

Carrolee Barlow 2 collaborations

Gregory A Elder 2 collaborations

Anna Klopot 2 collaborations

Nicholas K Akers 2 collaborations

Katyayani Sukhavasi 2 collaborations

Oscar Franzén 2 collaborations

Kristin L Ayers 2 collaborations

Marcus A Badgeley 2 collaborations

Kipp W Johnson 2 collaborations

Bruce J Darrow 2 collaborations

Eimear E Kenny 2 collaborations

Christer Betsholtz 2 collaborations

Raili Ermel 2 collaborations

Josefin Skogsberg 2 collaborations

Arno Ruusalepp 2 collaborations

Hongxia Ren 2 collaborations

Shuyu D Li 2 collaborations

Shivani Agarwal 2 collaborations

Minghui Wang 2 collaborations

Soong Ho Kim 2 collaborations

Szilvia Heja 2 collaborations

Bin Zhang 2 collaborations

Cory C Funk 2 collaborations

Molly Smullen 2 collaborations

Meagan N Olson 2 collaborations

Liam F Murray 2 collaborations

Pepper Dawes 2 collaborations

George M Church 2 collaborations

Elaine T Lim 2 collaborations

Yingleong Chan 2 collaborations

Soong H Kim 1 collaboration

Priscilla Yevoo 1 collaboration

Masato Sadahiro 1 collaboration

Brian Kidd 1 collaboration

Braden T Tierney 1 collaboration

JangKeun Kim 1 collaboration

Eliah G Overbey 1 collaboration

Krista A Ryon 1 collaboration

Jonathan Foox 1 collaboration

Maria Sierra 1 collaboration

Chandrima Bhattacharya 1 collaboration

Namita Damle 1 collaboration

Deena Najjar 1 collaboration

Jiwoon Park 1 collaboration

Sebastian Garcia Medina 1 collaboration

Nadia Houerbi 1 collaboration

Cem Meydan 1 collaboration

Jeremy Wain Hershberg 1 collaboration

Jake Qiu 1 collaboration

Ashley Kleinman 1 collaboration

Gabe Al Ghalith 1 collaboration

Matthew MacKay 1 collaboration

Evan E Afshin 1 collaboration

Raja Dhir 1 collaboration

Joseph Borg 1 collaboration

Christine Gatt 1 collaboration

Nicholas Brereton 1 collaboration

Semir Beyaz 1 collaboration

Kasthuri J Venkateswaran 1 collaboration

Kelly Blease 1 collaboration

Juan Moreno 1 collaboration

Andrew Boddicker 1 collaboration

Junhua Zhao 1 collaboration

Bryan Lajoie 1 collaboration

Ryan T Scott 1 collaboration

Andrew Altomare 1 collaboration

Semyon Kruglyak 1 collaboration

Shawn Levy 1 collaboration

George Church 1 collaboration

Christopher E Mason 1 collaboration

C C Zouboulis 1 collaboration

A Nogueira da Costa 1 collaboration

E Makrantonaki 1 collaboration

X X Hou 1 collaboration

D Almansouri 1 collaboration

J T Dudley 1 collaboration

H Edwards 1 collaboration

O Balthasar 1 collaboration

G B E Jemec 1 collaboration

N G Bonitsis 1 collaboration

G Nikolakis 1 collaboration

D Trebing 1 collaboration

K C Zouboulis 1 collaboration

A M Hossini 1 collaboration

Yinghua Chen 1 collaboration

Georgina Perez Garcia 1 collaboration

Jacqueline Buros 1 collaboration

Yanzhuang Wang 1 collaboration

Eyal Klang 1 collaboration

Undina Gisladottir 1 collaboration

Maxence Vandromme 1 collaboration

Yakeel T Quiroz 1 collaboration

Joseph F Arboleda-Velasquez 1 collaboration

Nicholas P Tatonetti 1 collaboration

Loukia N Lili 1 collaboration

Itziar Frades 1 collaboration

Simon Koplev 1 collaboration

Husain A Talukdar 1 collaboration

Heidi M Crane 1 collaboration

Paul K Crane 1 collaboration

Inga Peter 1 collaboration

D A Chudakova 1 collaboration

D Trubetskoy 1 collaboration

G Baida 1 collaboration

P Bhalla 1 collaboration

I Budunova 1 collaboration

Georgina Perez-Garcia 1 collaboration

Wen Zhang 1 collaboration

Georgios Voloudakis 1 collaboration

Veera M Rajagopal 1 collaboration

Yungil Kim 1 collaboration

John F Fullard 1 collaboration

Gabriel E Hoffman 1 collaboration

Panos Roussos 1 collaboration

Salida Mirzoeva 1 collaboration

Ruth F Itzhaki 1 collaboration

Todd E Golde 1 collaboration

Michael T Heneka 1 collaboration

Ekaterina A Lesovaya 1 collaboration

Alena V Savinkova 1 collaboration

Olga V Morozova 1 collaboration

Evgeniya S Lylova 1 collaboration

Ekaterina M Zhidkova 1 collaboration

Evgeny P Kulikov 1 collaboration

Kirill I Kirsanov 1 collaboration

Marianna G Yakubovskaya 1 collaboration

Leo I Gordon 1 collaboration

Michael Wainberg 1 collaboration

Tain Luquez 1 collaboration

David M Koelle 1 collaboration

Christine Johnston 1 collaboration

Martin Darvas 1 collaboration

Dipankar Bhattacharya 1 collaboration

Christine Becker 1 collaboration

Nicolas Goossens 1 collaboration

Jacqueline Novik 1 collaboration

Maria Isabel Fiel 1 collaboration

Leslie P Cousens 1 collaboration

Björn Magnusson 1 collaboration

Anna Backmark 1 collaboration

Ryan Hicks 1 collaboration

Scott L Friedman 1 collaboration

Madhusoodhanan Suresh 1 collaboration

Guang Yan 1 collaboration

Nathaniel J Barton 1 collaboration

Jivanna N Mason 1 collaboration

Yucheng Zhang 1 collaboration

Aria A Fernandez-Fontaine 1 collaboration

Lusheng Song 1 collaboration

Femina Rauf 1 collaboration

Ching-Wen Hou 1 collaboration

Ji Qiu 1 collaboration

Vel Murugan 1 collaboration

Yunro Chung 1 collaboration

Huafang Lai 1 collaboration

Deborah Adam 1 collaboration

D Mitchell Magee 1 collaboration

Guillermo Trivino Soto 1 collaboration

Milene Peterson 1 collaboration

Karen S Anderson 1 collaboration

Stephen G Rice 1 collaboration

Jin G Park 1 collaboration

Joshua LaBaer 1 collaboration

Ke Xu 1 collaboration

Roman Kosoy 1 collaboration

Sudhir Kumar 1 collaboration

Li Liu 1 collaboration

Hao-Chih Lee 1 collaboration

Geidy E Serrano 1 collaboration

Jessica E Walker 1 collaboration

Richard Arce 1 collaboration

Michael J Glass 1 collaboration

Daisy Vargas 1 collaboration

Lucia I Sue 1 collaboration

Anthony J Intorcia 1 collaboration

Courtney M Nelson 1 collaboration

Javon Oliver 1 collaboration

Jaclyn Papa 1 collaboration

Aryck Russell 1 collaboration

Katsuko E Suszczewicz 1 collaboration

Claryssa I Borja 1 collaboration

Christine Belden 1 collaboration

Danielle Goldfarb 1 collaboration

David Shprecher 1 collaboration

Alireza Atri 1 collaboration

Charles H Adler 1 collaboration

Holly A Shill 1 collaboration

Erika Driver-Dunckley 1 collaboration

Shyamal H Mehta 1 collaboration

Matthew J Huentelman 1 collaboration

Joseph L Peters 1 collaboration

Ellie Alevritis 1 collaboration

Christian Bimi 1 collaboration

Joseph P Mizgerd 1 collaboration

Thomas J Montine 1 collaboration

Marc Desforges 1 collaboration

James L Zehnder 1 collaboration

Malaya K Sahoo 1 collaboration

Haiyu Zhang 1 collaboration

Daniel Solis 1 collaboration

Benjamin A Pinsky 1 collaboration

Michael Deture 1 collaboration

Dennis W Dickson 1 collaboration

Thomas G Beach 1 collaboration

Priyanka Baloni 1 collaboration

Nathan D Price 1 collaboration

Julia M Reichert 1 collaboration

Christina E Baer 1 collaboration