Eric E Schadt

Affiliations
  • Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Mount Sinai School of Medicine, New York, NY, USA.
  • Sema4, Stamford, CT, USA.

Publications (46)

Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis.

Nature microbiology
Avec: Pedro H Oliveira , John W Ribis , Elizabeth M Garrett , Dominika Trzilova , Alex Kim , Ognjen Sekulovic , Edward A Mead , Theodore Pak , Shijia Zhu , Gintaras Deikus , Marie Touchon , Martha Lewis-Sandari , Colleen Beckford , Nathalie E Zeitouni , Deena R Altman , Elizabeth Webster , Irina Oussenko , Supinda Bunyavanich , Aneel K Aggarwal , Ali Bashir , Gopi Patel , Frances Wallach , Camille Hamula , Shirish Huprikar , Eric E Schadt , Robert Sebra , Harm van Bakel , Andrew Kasarskis , Rita Tamayo , Aimee Shen , Gang Fang

Functional interpretation of genetic variants using deep learning predicts impact on chromatin accessibility and histone modification.

Nucleic acids research
Avec: Gabriel E Hoffman , Jaroslav Bendl , Kiran Girdhar , Eric E Schadt , Panos Roussos

Deciphering bacterial epigenomes using modern sequencing technologies.

Nature reviews. Genetics
Avec: John Beaulaurier , Eric E Schadt , Gang Fang

Differential activity of transcribed enhancers in the prefrontal cortex of 537 cases with schizophrenia and controls.

Molecular psychiatry
Avec: Mads E Hauberg , John F Fullard , Lingxue Zhu , Ariella T Cohain , Claudia Giambartolomei , Ruth Misir , Sarah Reach , Jessica S Johnson , Minghui Wang , Manuel Mattheisen , Anders Dupont Børglum , Bin Zhang , Solveig K Sieberts , Mette A Peters , Enrico Domenici , Eric E Schadt , Bernie Devlin , Pamela Sklar , Kathryn Roeder , Panos Roussos , Auteur inconnu

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Nature genetics
Avec: Rainer Malik , Ganesh Chauhan , Matthew Traylor , Muralidharan Sargurupremraj , Yukinori Okada , Aniket Mishra , Loes Rutten-Jacobs , Anne-Katrin Giese , Sander W van der Laan , Solveig Gretarsdottir , Christopher D Anderson , Michael Chong , Hieab H H Adams , Tetsuro Ago , Peter Almgren , Philippe Amouyel , Hakan Ay , Traci M Bartz , Oscar R Benavente , Steve Bevan , Giorgio B Boncoraglio , Robert D Brown , Adam S Butterworth , Caty Carrera , Cara L Carty , Daniel I Chasman , Wei-Min Chen , John W Cole , Adolfo Correa , Ioana Cotlarciuc , Carlos Cruchaga , John Danesh , Paul I W de Bakker , Anita L DeStefano , Marcel den Hoed , Qing Duan , Stefan T Engelter , Guido J Falcone , Rebecca F Gottesman , Raji P Grewal , Vilmundur Gudnason , Stefan Gustafsson , Jeffrey Haessler , Tamara B Harris , Ahamad Hassan , Aki S Havulinna , Susan R Heckbert , Elizabeth G Holliday , George Howard , Fang-Chi Hsu , Hyacinth I Hyacinth , M Arfan Ikram , Erik Ingelsson , Marguerite R Irvin , Xueqiu Jian , Jordi Jiménez-Conde , Julie A Johnson , J Wouter Jukema , Masahiro Kanai , Keith L Keene , Brett M Kissela , Dawn O Kleindorfer , Charles Kooperberg , Michiaki Kubo , Leslie A Lange , Carl D Langefeld , Claudia Langenberg , Lenore J Launer , Jin-Moo Lee , Robin Lemmens , Didier Leys , Cathryn M Lewis , Wei-Yu Lin , Arne G Lindgren , Erik Lorentzen , Patrik K Magnusson , Jane Maguire , Ani Manichaikul , Patrick F McArdle , James F Meschia , Braxton D Mitchell , Thomas H Mosley , Michael A Nalls , Toshiharu Ninomiya , Martin J O'Donnell , Bruce M Psaty , Sara L Pulit , Kristiina Rannikmäe , Alexander P Reiner , Kathryn M Rexrode , Kenneth Rice , Stephen S Rich , Paul M Ridker , Natalia S Rost , Peter M Rothwell , Jerome I Rotter , Tatjana Rundek , Ralph L Sacco , Saori Sakaue , Michele M Sale , Veikko Salomaa , Bishwa R Sapkota , Reinhold Schmidt , Carsten O Schmidt , Ulf Schminke , Pankaj Sharma , Agnieszka Slowik , Cathie L M Sudlow , Christian Tanislav , Turgut Tatlisumak , Kent D Taylor , Vincent N S Thijs , Gudmar Thorleifsson , Unnur Thorsteinsdottir , Steffen Tiedt , Stella Trompet , Christophe Tzourio , Cornelia M van Duijn , Matthew Walters , Nicholas J Wareham , Sylvia Wassertheil-Smoller , James G Wilson , Kerri L Wiggins , Qiong Yang , Salim Yusuf , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Joshua C Bis , Tomi Pastinen , Arno Ruusalepp , Eric E Schadt , Simon Koplev , Johan L M Björkegren , Veronica Codoni , Mete Civelek , Nicholas L Smith , David A Trégouët , Ingrid E Christophersen , Carolina Roselli , Steven A Lubitz , Patrick T Ellinor , E Shyong Tai , Jaspal S Kooner , Norihiro Kato , Jiang He , Pim van der Harst , Paul Elliott , John C Chambers , Fumihiko Takeuchi , Andrew D Johnson , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Dharambir K Sanghera , Olle Melander , Christina Jern , Daniel Strbian , Israel Fernandez-Cadenas , W T Longstreth , Arndt Rolfs , Jun Hata , Daniel Woo , Jonathan Rosand , Guillaume Pare , Jemma C Hopewell , Danish Saleheen , Kari Stefansson , Bradford B Worrall , Steven J Kittner , Sudha Seshadri , Myriam Fornage , Hugh S Markus , Joanna M M Howson , Yoichiro Kamatani , Stephanie Debette , Martin Dichgans

Intratumoral heterogeneity and clonal evolution in liver cancer.

Nature communications
Avec: Bojan Losic , Amanda J Craig , Carlos Villacorta-Martin , Sebastiao N Martins-Filho , Nicholas Akers , Xintong Chen , Mehmet E Ahsen , Johann von Felden , Ismail Labgaa , Delia DʹAvola , Kimaada Allette , Sergio A Lira , Glaucia C Furtado , Teresa Garcia-Lezana , Paula Restrepo , Ashley Stueck , Stephen C Ward , Maria I Fiel , Spiros P Hiotis , Ganesh Gunasekaran , Daniela Sia , Eric E Schadt , Robert Sebra , Myron Schwartz , Josep M Llovet , Swan Thung , Gustavo Stolovitzky , Augusto Villanueva

Cytotoxic lymphocytes are dysregulated in multisystem inflammatory syndrome in children.

medRxiv : the preprint server for health sciences
Avec: Noam D Beckmann , Phillip H Comella , Esther Cheng , Lauren Lepow , Aviva G Beckmann , Konstantinos Mouskas , Nicole W Simons , Gabriel E Hoffman , Nancy J Francoeur , Diane Marie Del Valle , Gurpawan Kang , Emily Moya , Lillian Wilkins , Jessica Le Berichel , Christie Chang , Robert Marvin , Sharlene Calorossi , Alona Lansky , Laura Walker , Nancy Yi , Alex Yu , Matthew Hartnett , Melody Eaton , Sandra Hatem , Hajra Jamal , Alara Akyatan , Alexandra Tabachnikova , Lora E Liharska , Liam Cotter , Brian Fennessey , Akhil Vaid , Guillermo Barturen , Scott R Tyler , Hardik Shah , Ying-Chih Wang , Shwetha Hara Sridhar , Juan Soto , Swaroop Bose , Kent Madrid , Ethan Ellis , Elyze Merzier , Konstantinos Vlachos , Nataly Fishman , Manying Tin , Melissa Smith , Hui Xie , Manishkumar Patel , Kimberly Argueta , Jocelyn Harris , Neha Karekar , Craig Batchelor , Jose Lacunza , Mahlet Yishak , Kevin Tuballes , Leisha Scott , Arvind Kumar , Suraj Jaladanki , Ryan Thompson , Evan Clark , Bojan Losic , Auteur inconnu , Jun Zhu , Wenhui Wang , Andrew Kasarskis , Benjamin S Glicksberg , Girish Nadkarni , Dusan Bogunovic , Cordelia Elaiho , Sandeep Gangadharan , George Ofori-Amanfo , Kasey Alesso-Carra , Kenan Onel , Karen M Wilson , Carmen Argmann , Marta E Alarcón-Riquelme , Thomas U Marron , Adeeb Rahman , Seunghee Kim-Schulze , Sacha Gnjatic , Bruce D Gelb , Miriam Merad , Robert Sebra , Eric E Schadt , Alexander W Charney

Dual transcriptomic and epigenomic study of reaction severity in peanut-allergic children.

The Journal of allergy and clinical immunology
Avec: Anh N Do , Corey T Watson , Ariella T Cohain , Robert S Griffin , Alexander Grishin , Robert A Wood , A Wesley Burks , Stacie M Jones , Amy Scurlock , Donald Y M Leung , Hugh A Sampson , Scott H Sicherer , Andrew J Sharp , Eric E Schadt , Supinda Bunyavanich

Integrative Analysis of the Inflammatory Bowel Disease Serum Metabolome Improves Our Understanding of Genetic Etiology and Points to Novel Putative Therapeutic Targets.

Gastroenterology
Avec: Antonio F Di'Narzo , Sander M Houten , Roman Kosoy , Ruiqi Huang , Frédéric M Vaz , Ruixue Hou , Gabrielle Wei , Wenhui Wang , Phillip H Comella , Tetyana Dodatko , Eduard Rogatsky , Aleksandar Stojmirovic , Carrie Brodmerkel , Jacqueline Perrigoue , Amy Hart , Mark Curran , Joshua R Friedman , Jun Zhu , Manasi Agrawal , Judy Cho , Ryan Ungaro , Marla C Dubinsky , Bruce E Sands , Mayte Suárez-Fariñas , Eric E Schadt , Jean-Frédéric Colombel , Andrew Kasarskis , Ke Hao , Carmen Argmann

Targeted Next-Generation Sequencing Reveals Exceptionally High Rates of Molecular Driver Mutations in Never-Smokers With Lung Adenocarcinoma.

The oncologist
Avec: Philip C Mack , Michael I Klein , Kristin L Ayers , Xiang Zhou , Sunny Guin , Marc Fink , Michael Rossi , Hussam Ai-Kateb , Timmy O'Connell , Feras M Hantash , William K Oh , Scott Newman , Eric E Schadt , Rong Chen , Fred R Hirsch

Inpatient Administration of Alpha-1-Adrenergic Receptor Blocking Agents Reduces Mortality in Male COVID-19 Patients.

Frontiers in medicine
Avec: Shilong Li , Tomi Jun , Jonathan Tyler , Emilio Schadt , Yu-Han Kao , Zichen Wang , Maximilian F Konig , Chetan Bettegowda , Joshua T Vogelstein , Nickolas Papadopoulos , Ramon E Parsons , Rong Chen , Eric E Schadt , Li Li , William K Oh

Anti-correlated feature selection prevents false discovery of subpopulations in scRNAseq.

Nature communications
Avec: Scott R Tyler , Daniel Lozano-Ojalvo , Ernesto Guccione , Eric E Schadt

A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility.

NPJ genomic medicine
Avec: Georgios Voloudakis , James M Vicari , Sanan Venkatesh , Gabriel E Hoffman , Kristina Dobrindt , Wen Zhang , Noam D Beckmann , Christina A Higgins , Stathis Argyriou , Shan Jiang , Daisy Hoagland , Lina Gao , André Corvelo , Kelly Cho , Kyung Min Lee , Jiantao Bian , Jennifer S Lee , Sudha K Iyengar , Shiuh-Wen Luoh , Schahram Akbarian , Robert Striker , Themistocles L Assimes , Eric E Schadt , Julie A Lynch , Miriam Merad , Benjamin R tenOever , Alexander W Charney , Auteur inconnu , Auteur inconnu , Kristen J Brennand , John F Fullard , Panos Roussos

Biopsy and blood-based molecular biomarker of inflammation in IBD.

Gut
Avec: Carmen Argmann , Ruixue Hou , Ryan C Ungaro , Haritz Irizar , Zainab Al-Taie , Ruiqi Huang , Roman Kosoy , Swati Venkat , Won-Min Song , Antonio F Di'Narzo , Bojan Losic , Ke Hao , Lauren Peters , Phillip H Comella , Gabrielle Wei , Ashish Atreja , Milind Mahajan , Alina Iuga , Prerak T Desai , Patrick Branigan , Aleksandar Stojmirovic , Jacqueline Perrigoue , Carrie Brodmerkel , Mark Curran , Joshua R Friedman , Amy Hart , Esi Lamousé-Smith , Jan Wehkamp , Saurabh Mehandru , Eric E Schadt , Bruce E Sands , Marla C Dubinsky , Jean-Frederic Colombel , Andrew Kasarskis , Mayte Suárez-Fariñas

A mechanistic framework for cardiometabolic and coronary artery diseases.

Nature cardiovascular research
Avec: Simon Koplev , Marcus Seldin , Katyayani Sukhavasi , Raili Ermel , Shichao Pang , Lingyao Zeng , Sean Bankier , Antonio Di Narzo , Haoxiang Cheng , Vamsidhar Meda , Angela Ma , Husain Talukdar , Ariella Cohain , Letizia Amadori , Carmen Argmann , Sander M Houten , Oscar Franzén , Giuseppe Mocci , Omar A Meelu , Kiyotake Ishikawa , Carl Whatling , Anamika Jain , Rajeev Kumar Jain , Li-Ming Gan , Chiara Giannarelli , Panos Roussos , Ke Hao , Heribert Schunkert , Tom Michoel , Arno Ruusalepp , Eric E Schadt , Jason C Kovacic , Aldon J Lusis , Johan L M Björkegren

A study of gene expression in the living human brain.

medRxiv : the preprint server for health sciences
Avec: Lora E Liharska , You Jeong Park , Kimia Ziafat , Lillian Wilkins , Hannah Silk , Lisa M Linares , Eric Vornholt , Brendan Sullivan , Vanessa Cohen , Prashant Kota , Claudia Feng , Esther Cheng , Emily Moya , Ryan C Thompson , Jessica S Johnson , Marysia-Kolbe Rieder , Jia Huang , Joseph Scarpa , Alice Hashemi , Jairo Polanco , Matthew A Levin , Girish N Nadkarni , Robert Sebra , John Crary , Eric E Schadt , Noam D Beckmann , Brian H Kopell , Alexander W Charney

Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females.

Cells
Avec: Allen L Pan , Mickael Audrain , Emmy Sakakibara , Rajeev Joshi , Xiaodong Zhu , Qian Wang , Minghui Wang , Noam D Beckmann , Eric E Schadt , Sam Gandy , Bin Zhang , Michelle E Ehrlich , Stephen R Salton

Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice.

bioRxiv : the preprint server for biology
Avec: Allen L Pan , Mickael Audrain , Emmy Sakakibara , Rajeev Joshi , Xiaodong Zhu , Qian Wang , Minghui Wang , Noam D Beckmann , Eric E Schadt , Sam Gandy , Bin Zhang , Michelle E Ehrlich , Stephen R Salton

Genomic analyses implicate noncoding de novo variants in congenital heart disease.

Nature genetics
Avec: Felix Richter , Sarah U Morton , Seong Won Kim , Alexander Kitaygorodsky , Lauren K Wasson , Kathleen M Chen , Jian Zhou , Hongjian Qi , Nihir Patel , Steven R DePalma , Michael Parfenov , Jason Homsy , Joshua M Gorham , Kathryn B Manheimer , Matthew Velinder , Andrew Farrell , Gabor Marth , Eric E Schadt , Jonathan R Kaltman , Jane W Newburger , Alessandro Giardini , Elizabeth Goldmuntz , Martina Brueckner , Richard Kim , George A Porter , Daniel Bernstein , Wendy K Chung , Deepak Srivastava , Martin Tristani-Firouzi , Olga G Troyanskaya , Diane E Dickel , Yufeng Shen , Jonathan G Seidman , Christine E Seidman , Bruce D Gelb

Contribution of Gene Regulatory Networks to Heritability of Coronary Artery Disease.

Journal of the American College of Cardiology
Avec: Lingyao Zeng , Husain A Talukdar , Simon Koplev , Chiara Giannarelli , Torbjörn Ivert , Li-Ming Gan , Arno Ruusalepp , Eric E Schadt , Jason C Kovacic , Aldons J Lusis , Tom Michoel , Heribert Schunkert , Johan L M Björkegren

Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau.

Molecular psychiatry
Avec: Mickael Audrain , Jean-Vianney Haure-Mirande , Minghui Wang , Soong Ho Kim , Tomas Fanutza , Paramita Chakrabarty , Paul Fraser , Peter H St George-Hyslop , Todd E Golde , Robert D Blitzer , Eric E Schadt , Bin Zhang , Michelle E Ehrlich , Sam Gandy

An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease.

Nature communications
Avec: Ariella T Cohain , William T Barrington , Daniel M Jordan , Noam D Beckmann , Carmen A Argmann , Sander M Houten , Alexander W Charney , Raili Ermel , Katyayani Sukhavasi , Oscar Franzen , Simon Koplev , Carl Whatling , Gillian M Belbin , Jialiang Yang , Ke Hao , Eimear E Kenny , Zhidong Tu , Jun Zhu , Li-Ming Gan , Ron Do , Chiara Giannarelli , Jason C Kovacic , Arno Ruusalepp , Aldons J Lusis , Johan L M Bjorkegren , Eric E Schadt

Detecting and phasing minor single-nucleotide variants from long-read sequencing data.

Nature communications
Avec: Zhixing Feng , Jose C Clemente , Brandon Wong , Eric E Schadt

Prognostic value of polygenic risk scores for adults with psychosis.

Nature medicine
Avec: Isotta Landi , Deepak A Kaji , Liam Cotter , Tielman Van Vleck , Gillian Belbin , Michael Preuss , Ruth J F Loos , Eimear Kenny , Benjamin S Glicksberg , Noam D Beckmann , Paul O'Reilly , Eric E Schadt , Eric D Achtyes , Peter F Buckley , Douglas Lehrer , Dolores P Malaspina , Steven A McCarroll , Mark H Rapaport , Ayman H Fanous , Michele T Pato , Carlos N Pato , Tim B Bigdeli , Girish N Nadkarni , Alexander W Charney

Integrative network analysis of early-stage lung adenocarcinoma identifies aurora kinase inhibition as interceptor of invasion and progression.

Nature communications
Avec: Seungyeul Yoo , Abhilasha Sinha , Dawei Yang , Nasser K Altorki , Radhika Tandon , Wenhui Wang , Deebly Chavez , Eunjee Lee , Ayushi S Patel , Takashi Sato , Ranran Kong , Bisen Ding , Eric E Schadt , Hideo Watanabe , Pierre P Massion , Alain C Borczuk , Jun Zhu , Charles A Powell

Improving preeclampsia risk prediction by modeling pregnancy trajectories from routinely collected electronic medical record data.

NPJ digital medicine
Avec: Shilong Li , Zichen Wang , Luciana A Vieira , Amanda B Zheutlin , Boshu Ru , Emilio Schadt , Pei Wang , Alan B Copperman , Joanne L Stone , Susan J Gross , Yu-Han Kao , Yan Kwan Lau , Siobhan M Dolan , Eric E Schadt , Li Li

Identification of Let-7 miRNA Activity as a Prognostic Biomarker of SHH Medulloblastoma.

Cancers
Avec: Maximillian S Westphal , Eunjee Lee , Eric E Schadt , Giselle S Sholler , Jun Zhu

Late preterm antenatal corticosteroids in singleton and twin gestations: a retrospective cohort study.

BMC pregnancy and childbirth
Avec: Luciana A Vieira , Yu-Han Kao , Despina S Tsevdos , Yan Kwan Lau , Zichen Wang , Shilong Li , Amanda B Zheutlin , Susan J Gross , Joanne L Stone , Siobhan M Dolan , Eric E Schadt , Li Li

Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence.

Cell reports
Avec: Radoslav Savić , Jialiang Yang , Simon Koplev , Mahru C An , Priyanka L Patel , Robert N O'Brien , Brittany N Dubose , Tetyana Dodatko , Eduard Rogatsky , Katyayani Sukhavasi , Raili Ermel , Arno Ruusalepp , Sander M Houten , Jason C Kovacic , Andrew F Stewart , Christopher B Yohn , Eric E Schadt , Remi-Martin Laberge , Johan L M Björkegren , Zhidong Tu , Carmen Argmann

Divergent landscapes of A-to-I editing in postmortem and living human brain.

medRxiv : the preprint server for health sciences
Avec: Miguel Rodriguez de Los Santos , Brian H Kopell , Ariela Buxbaum Grice , Gauri Ganesh , Andy Yang , Pardis Amini , Lora E Liharska , Eric Vornholt , John F Fullard , Pengfei Dong , Eric Park , Sarah Zipkowitz , Deepak A Kaji , Ryan C Thompson , Donjing Liu , You Jeong Park , Esther Cheng , Kimia Ziafat , Emily Moya , Brian Fennessy , Lillian Wilkins , Hannah Silk , Lisa M Linares , Brendan Sullivan , Vanessa Cohen , Prashant Kota , Claudia Feng , Jessica S Johnson , Marysia-Kolbe Rieder , Joseph Scarpa , Girish N Nadkarni , Minghui Wang , Bin Zhang , Pamela Sklar , Noam D Beckmann , Eric E Schadt , Panos Roussos , Alexander W Charney , Michael S Breen

Multiomic foundations of human prefrontal cortex tissue function.

medRxiv : the preprint server for health sciences
Avec: Brian H Kopell , Deepak A Kaji , Lora E Liharska , Eric Vornholt , Alissa Valentine , Anina Lund , Alice Hashemi , Ryan C Thompson , Terry Lohrenz , Jessica S Johnson , Nicole Bussola , Esther Cheng , You Jeong Park , Punit Shah , Weiping Ma , Richard Searfoss , Salman Qasim , Gregory M Miller , Nischal Mahaveer Chand , Alisha Aristel , Jack Humphrey , Lillian Wilkins , Kimia Ziafat , Hannah Silk , Lisa M Linares , Brendan Sullivan , Claudia Feng , Seth R Batten , Dan Bang , Leonardo S Barbosa , Thomas Twomey , Jason P White , Marina Vannucci , Beniamino Hadj-Amar , Vanessa Cohen , Prashant Kota , Emily Moya , Marysia-Kolbe Rieder , Martijn Figee , Girish N Nadkarni , Michael S Breen , Kenneth T Kishida , Joseph Scarpa , Douglas M Ruderfer , Niven R Narain , Pei Wang , Michael A Kiebish , Eric E Schadt , Ignacio Saez , P Read Montague , Noam D Beckmann , Alexander W Charney

Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice.

Frontiers in aging neuroscience
Avec: Allen L Pan , Mickael Audrain , Emmy Sakakibara , Rajeev Joshi , Xiaodong Zhu , Qian Wang , Minghui Wang , Noam D Beckmann , Eric E Schadt , Sam Gandy , Bin Zhang , Michelle E Ehrlich , Stephen R Salton

Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer.

Cell
Avec: Francesca Petralia , Nicole Tignor , Boris Reva , Mateusz Koptyra , Shrabanti Chowdhury , Dmitry Rykunov , Azra Krek , Weiping Ma , Yuankun Zhu , Jiayi Ji , Anna Calinawan , Jeffrey R Whiteaker , Antonio Colaprico , Vasileios Stathias , Tatiana Omelchenko , Xiaoyu Song , Pichai Raman , Yiran Guo , Miguel A Brown , Richard G Ivey , John Szpyt , Sanjukta Guha Thakurta , Marina A Gritsenko , Karl K Weitz , Gonzalo Lopez , Selim Kalayci , Zeynep H Gümüş , Seungyeul Yoo , Felipe da Veiga Leprevost , Hui-Yin Chang , Karsten Krug , Lizabeth Katsnelson , Ying Wang , Jacob J Kennedy , Uliana J Voytovich , Lei Zhao , Krutika S Gaonkar , Brian M Ennis , Bo Zhang , Valerie Baubet , Lamiya Tauhid , Jena V Lilly , Jennifer L Mason , Bailey Farrow , Nathan Young , Sarah Leary , Jamie Moon , Vladislav A Petyuk , Javad Nazarian , Nithin D Adappa , James N Palmer , Robert M Lober , Samuel Rivero-Hinojosa , Liang-Bo Wang , Joshua M Wang , Matilda Broberg , Rosalie K Chu , Ronald J Moore , Matthew E Monroe , Rui Zhao , Richard D Smith , Jun Zhu , Ana I Robles , Mehdi Mesri , Emily Boja , Tara Hiltke , Henry Rodriguez , Bing Zhang , Eric E Schadt , D R Mani , Li Ding , Antonio Iavarone , Maciej Wiznerowicz , Stephan Schürer , Xi S Chen , Allison P Heath , Jo Lynne Rokita , Alexey I Nesvizhskii , David Fenyö , Karin D Rodland , Tao Liu , Steven P Gygi , Amanda G Paulovich , Adam C Resnick , Phillip B Storm , Brian R Rood , Pei Wang , Auteur inconnu , Auteur inconnu

A composite biomarker of neutrophil-lymphocyte ratio and hemoglobin level correlates with clinical response to PD-1 and PD-L1 inhibitors in advanced non-small cell lung cancers.

BMC cancer
Avec: Kristin L Ayers , Meng Ma , Gaspard Debussche , David Corrigan , Jonathan McCafferty , Kyeryoung Lee , Scott Newman , Xiang Zhou , Fred R Hirsch , Philip C Mack , Jane J Liu , Eric E Schadt , Rong Chen , Shuyu D Li

A Network Analysis of Multiple Myeloma Related Gene Signatures.

Cancers
Avec: Yu Liu , Haocheng Yu , Seungyeul Yoo , Eunjee Lee , Alessandro Laganà , Samir Parekh , Eric E Schadt , Li Wang , Jun Zhu

Intestinal Inflammation Modulates the Expression of ACE2 and TMPRSS2 and Potentially Overlaps With the Pathogenesis of SARS-CoV-2-related Disease.

Gastroenterology
Avec: Mayte Suárez-Fariñas , Minami Tokuyama , Gabrielle Wei , Ruiqi Huang , Alexandra Livanos , Divya Jha , Anais Levescot , Haritz Irizar , Roman Kosoy , Sascha Cording , Wenhui Wang , Bojan Losic , Ryan C Ungaro , Antonio Di'Narzo , Gustavo Martinez-Delgado , Maria Suprun , Michael J Corley , Aleksandar Stojmirovic , Sander M Houten , Lauren Peters , Mark Curran , Carrie Brodmerkel , Jacqueline Perrigoue , Joshua R Friedman , Ke Hao , Eric E Schadt , Jun Zhu , Huaibin M Ko , Judy Cho , Marla C Dubinsky , Bruce E Sands , Lishomwa Ndhlovu , Nadine Cerf-Bensusan , Andrew Kasarskis , Jean-Frederic Colombel , Noam Harpaz , Carmen Argmann , Saurabh Mehandru

Machine Learning to Predict Mortality and Critical Events in a Cohort of Patients With COVID-19 in New York City: Model Development and Validation.

Journal of medical Internet research
Avec: Akhil Vaid , Sulaiman Somani , Adam J Russak , Jessica K De Freitas , Fayzan F Chaudhry , Ishan Paranjpe , Kipp W Johnson , Samuel J Lee , Riccardo Miotto , Felix Richter , Shan Zhao , Noam D Beckmann , Nidhi Naik , Arash Kia , Prem Timsina , Anuradha Lala , Manish Paranjpe , Eddye Golden , Matteo Danieletto , Manbir Singh , Dara Meyer , Paul F O'Reilly , Laura Huckins , Patricia Kovatch , Joseph Finkelstein , Robert M Freeman , Edgar Argulian , Andrew Kasarskis , Bethany Percha , Judith A Aberg , Emilia Bagiella , Carol R Horowitz , Barbara Murphy , Eric J Nestler , Eric E Schadt , Judy H Cho , Carlos Cordon-Cardo , Valentin Fuster , Dennis S Charney , David L Reich , Erwin P Bottinger , Matthew A Levin , Jagat Narula , Zahi A Fayad , Allan C Just , Alexander W Charney , Girish N Nadkarni , Benjamin S Glicksberg

A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer.

Science advances
Avec: Erdem Bangi , Celina Ang , Peter Smibert , Andrew V Uzilov , Alexander G Teague , Yevgeniy Antipin , Rong Chen , Chana Hecht , Nelson Gruszczynski , Wesley J Yon , Denis Malyshev , Denise Laspina , Isaiah Selkridge , Hope Rainey , Aye S Moe , Chun Yee Lau , Patricia Taik , Eric Wilck , Aarti Bhardwaj , Max Sung , Sara Kim , Kendra Yum , Robert Sebra , Michael Donovan , Krzysztof Misiukiewicz , Eric E Schadt , Marshall R Posner , Ross L Cagan

Structural variation at the CYP2C locus: Characterization of deletion and duplication alleles.

Human mutation
Avec: Mariana R Botton , Xingwu Lu , Geping Zhao , Elena Repnikova , Yoshinori Seki , Andrea Gaedigk , Eric E Schadt , Lisa Edelmann , Stuart A Scott

Discovering genetic interactions bridging pathways in genome-wide association studies.

Nature communications
Avec: Gang Fang , Wen Wang , Vanja Paunic , Hamed Heydari , Michael Costanzo , Xiaoye Liu , Xiaotong Liu , Benjamin VanderSluis , Benjamin Oately , Michael Steinbach , Brian Van Ness , Eric E Schadt , Nathan D Pankratz , Charles Boone , Vipin Kumar , Chad L Myers

Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits.

Nature communications
Avec: Wen Zhang , Georgios Voloudakis , Veera M Rajagopal , Ben Readhead , Joel T Dudley , Eric E Schadt , Johan L M Björkegren , Yungil Kim , John F Fullard , Gabriel E Hoffman , Panos Roussos

Correction: Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden.

Molecular psychiatry
Avec: Jean-Vianney Haure-Mirande , Minghui Wang , Mickael Audrain , Tomas Fanutza , Soong Ho Kim , Szilvia Heja , Ben Readhead , Joel T Dudley , Robert D Blitzer , Eric E Schadt , Bin Zhang , Sam Gandy , Michelle E Ehrlich

Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease.

Nature communications
Avec: Noam D Beckmann , Wei-Jye Lin , Minghui Wang , Ariella T Cohain , Alexander W Charney , Pei Wang , Weiping Ma , Ying-Chih Wang , Cheng Jiang , Mickael Audrain , Phillip H Comella , Amanda K Fakira , Siddharth P Hariharan , Gillian M Belbin , Kiran Girdhar , Allan I Levey , Nicholas T Seyfried , Eric B Dammer , Duc Duong , James J Lah , Jean-Vianney Haure-Mirande , Ben Shackleton , Tomas Fanutza , Robert Blitzer , Eimear Kenny , Jun Zhu , Vahram Haroutunian , Pavel Katsel , Sam Gandy , Zhidong Tu , Michelle E Ehrlich , Bin Zhang , Stephen R Salton , Eric E Schadt

Author Correction: Sampling the host response to SARS-CoV-2 in hospitals under siege.

Nature medicine
Avec: Alexander W Charney , Nicole W Simons , Konstantinos Mouskas , Lauren Lepow , Esther Cheng , Jessica Le Berichel , Christie Chang , Robert Marvin , Diane Marie Del Valle , Sharlene Calorossi , Alona Lansky , Laura Walker , Manishkumar Patel , Hui Xie , Nancy Yi , Alex Yu , Gurpawan Kang , Lora E Liharska , Emily Moya , Matthew Hartnett , Sandra Hatem , Lillian Wilkins , Melody Eaton , Hajra Jamal , Kevin Tuballes , Steven T Chen , Jonathan Chung , Jocelyn Harris , Craig Batchelor , Jose Lacunza , Mahlet Yishak , Kimberly Argueta , Neha Karekar , Brian Lee , Geoffrey Kelly , Daniel Geanon , Diana Handler , John Leech , Hiyab Stefanos , Travis Dawson , Ieisha Scott , Nancy Francoeur , Jessica S Johnson , Akhil Vaid , Benjamin S Glicksberg , Girish N Nadkarni , Eric E Schadt , Bruce D Gelb , Adeeb Rahman , Robert Sebra , Glenn Martin , Auteur inconnu , Thomas Marron , Noam Beckmann , Seunghee Kim-Schulze , Sacha Gnjatic , Miriam Merad

Comparison of brain connectomes by MRI and genomics and its implication in Alzheimer's disease.

BMC medicine
Avec: Young Jae Woo , Panos Roussos , Vahram Haroutunian , Pavel Katsel , Samuel Gandy , Eric E Schadt , Jun Zhu , Auteur inconnu

IL10RB as a key regulator of COVID-19 host susceptibility and severity.

medRxiv : the preprint server for health sciences
Avec: Georgios Voloudakis , Gabriel Hoffman , Sanan Venkatesh , Kyung Min Lee , Kristina Dobrindt , James M Vicari , Wen Zhang , Noam D Beckmann , Shan Jiang , Daisy Hoagland , Jiantao Bian , Lina Gao , André Corvelo , Kelly Cho , Jennifer S Lee , Sudha K Iyengar , Shiuh-Wen Luoh , Schahram Akbarian , Robert Striker , Themistocles L Assimes , Eric E Schadt , Miriam Merad , Benjamin R tenOever , Alexander W Charney , Auteur inconnu , Auteur inconnu , Kristen J Brennand , Julie A Lynch , John F Fullard , Panos Roussos

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None None 25 collaborations
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Alexander W Charney 11 collaborations
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Panos Roussos 8 collaborations
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Yungil Kim 1 collaboration
Szilvia Heja 1 collaboration
Wei-Jye Lin 1 collaboration
Cheng Jiang 1 collaboration
Amanda K Fakira 1 collaboration
Siddharth P Hariharan 1 collaboration
Allan I Levey 1 collaboration
Nicholas T Seyfried 1 collaboration
Eric B Dammer 1 collaboration
Duc Duong 1 collaboration
James J Lah 1 collaboration
Ben Shackleton 1 collaboration
Robert Blitzer 1 collaboration
Steven T Chen 1 collaboration
Jonathan Chung 1 collaboration
Brian Lee 1 collaboration
Geoffrey Kelly 1 collaboration
Daniel Geanon 1 collaboration
Diana Handler 1 collaboration
John Leech 1 collaboration
Hiyab Stefanos 1 collaboration
Travis Dawson 1 collaboration
Ieisha Scott 1 collaboration
Nancy Francoeur 1 collaboration
Glenn Martin 1 collaboration
Thomas Marron 1 collaboration
Noam Beckmann 1 collaboration
Young Jae Woo 1 collaboration
Samuel Gandy 1 collaboration
Gabriel Hoffman 1 collaboration