Carl Amilon

Affiliations

Projects, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Pepparedsleden 1, 431 50 Gothenburg, Sweden.

Publications (11)

Antisense Therapy Attenuates Phospholamban p.(Arg14del) Cardiomyopathy in Mice and Reverses Protein Aggregation.

International journal of molecular sciences

Avec: Tim R Eijgenraam , Nienke M Stege , Vivian Oliveira Nunes Teixeira , Remco de Brouwer , Elisabeth M Schouten , Niels Grote Beverborg , Liu Sun , Daniela Später , Ralph Knöll , Kenny M Hansson , Carl Amilon , David Janzén , Steve T Yeh , Adam E Mullick , Peter van der Meer , Rudolf A de Boer , Herman H W Silljé

Pharmacokinetic-pharmacodynamic modelling of platelet response to ticagrelor in stable coronary artery disease and prior myocardial infarction patients.

British journal of clinical pharmacology

Avec: Magnus Åstrand , Carl Amilon , Daniel Röshammar , Anders Himmelmann , Dominick J Angiolillo , Robert F Storey , Paul A Gurbel , Marc P Bonaca , Bengt Hamrén

Population Pharmacodynamic Modeling of Eflornithine-Based Treatments Against Late-Stage Gambiense Human African Trypanosomiasis and Efficacy Predictions of L-eflornithine-Based Therapy.

The AAPS journal

Avec: Carl Amilon , Mikael Boberg , Joel Tarning , Angela Äbelö , Michael Ashton , Rasmus Jansson-Löfmark

Population Pharmacokinetics/Pharmacodynamics of Ticagrelor in Children with Sickle Cell Disease.

Clinical pharmacokinetics

Avec: Carl Amilon , Mohammad Niazi , Anders Berggren , Magnus Åstrand , Bengt Hamrén

Ticagrelor versus placebo for the reduction of vaso-occlusive crises in pediatric sickle cell disease: Rationale and design of a randomized, double-blind, parallel-group, multicenter phase 3 study (HESTIA3).

Contemporary clinical trials

Avec: Matthew M Heeney , Miguel R Abboud , Carl Amilon , Marielle Andersson , Jessie Githanga , Baba Inusa , Julie Kanter , Maria Leonsson-Zachrisson , Alan D Michelson , Anders R Berggren , Auteur inconnu

Biotransformation of the Novel Myeloperoxidase Inhibitor AZD4831 in Preclinical Species and Humans.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Ulrik Jurva , Lars Weidolf , Ann-Sofie Sandinge , Carina Leandersson , Anja Ekdahl , Xue-Qing Li , Thomas Antonsson , Johan Sundell , Kristina Westerlund , Carl Amilon , Tord Inghardt , V Sashi Gopaul

Application of Accelerator Mass Spectrometry to Characterize the Mass Balance Recovery and Disposition of AZD4831, a Novel Myeloperoxidase Inhibitor, following Administration of an Oral Radiolabeled Microtracer Dose in Humans.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Chandrali Bhattacharya , Ann-Sofie Sandinge , Ryan A Bragg , Maria Heijer , Jingjing Yan , Linda C Andersson , Ulrik Jurva , Marta Pelay-Gimeno , Wouter H J Vaes , Rianne A F de Ligt , Malin Gränfors , Carl Amilon , Eva-Lotte Lindstedt , Somasekhara R Menakuru , Pavlo Garkaviy , Lars Weidolf , V Sashi Gopaul

Disposition of orally administered atuliflapon, a novel 5-lipoxygenase-activating protein inhibitor in healthy participants.

Pharmacology research & perspectives

Avec: Xue-Qing Li , Bo Lindmark , Carl Amilon , Kristin Samuelsson , Lars Weidolf , Karin Nelander , Jane Knöchel , Maria Heijer , Ryan A Bragg , Malin Gränfors , Eva-Lotte Lindstedt , Sharan Sidhu , Pavlo Garkaviy , Hans Ericsson

Early Clinical Experience With AZD4831, A Novel Myeloperoxidase Inhibitor, Developed for Patients With Heart Failure With Preserved Ejection Fraction.

Clinical and translational science

Avec: Karin Nelander , Maria Lagerstrom-Fermer , Carl Amilon , Erik Michaëlsson , Maria Heijer , Magnus Kjaer , Muir Russell , David Han , Eva-Lotte Lindstedt , Carl Whatling , Li-Ming Gan , Hans Ericsson

Discovery and Early Clinical Development of an Inhibitor of 5-Lipoxygenase Activating Protein (AZD5718) for Treatment of Coronary Artery Disease.

Journal of medicinal chemistry

Avec: Daniel Pettersen , Johan Broddefalk , Hans Emtenäs , Martin A Hayes , Malin Lemurell , Marianne Swanson , Johan Ulander , Carl Whatling , Carl Amilon , Hans Ericsson , Annika Westin Eriksson , Kenneth Granberg , Alleyn T Plowright , Igor Shamovsky , Anita Dellsèn , Monica Sundqvist , Mats Någård , Eva-Lotte Lindstedt

Ticagrelor does not impact patient-reported pain in young adults with sickle cell disease: a multicentre, randomised phase IIb study.

British journal of haematology

Avec: Julie Kanter , Miguel R Abboud , Banu Kaya , Videlis Nduba , Carl Amilon , Christer Gottfridsson , Martin Rensfeldt , Maria Leonsson-Zachrisson , Auteur inconnu

Réseau de co-auteurs

Eva-Lotte Lindstedt 4 collaborations

Lars Weidolf 3 collaborations

Maria Heijer 3 collaborations

Hans Ericsson 3 collaborations

Magnus Åstrand 2 collaborations

Bengt Hamrén 2 collaborations

Miguel R Abboud 2 collaborations

Julie Kanter 2 collaborations

Maria Leonsson-Zachrisson 2 collaborations

None None 2 collaborations

Ulrik Jurva 2 collaborations

Ann-Sofie Sandinge 2 collaborations

Xue-Qing Li 2 collaborations

V Sashi Gopaul 2 collaborations

Ryan A Bragg 2 collaborations

Malin Gränfors 2 collaborations

Pavlo Garkaviy 2 collaborations

Karin Nelander 2 collaborations

Carl Whatling 2 collaborations

Tim R Eijgenraam 1 collaboration

Nienke M Stege 1 collaboration

Vivian Oliveira Nunes Teixeira 1 collaboration

Remco de Brouwer 1 collaboration

Elisabeth M Schouten 1 collaboration

Niels Grote Beverborg 1 collaboration

Liu Sun 1 collaboration

Daniela Später 1 collaboration

Ralph Knöll 1 collaboration

Kenny M Hansson 1 collaboration

David Janzén 1 collaboration

Steve T Yeh 1 collaboration

Adam E Mullick 1 collaboration

Peter van der Meer 1 collaboration

Rudolf A de Boer 1 collaboration

Herman H W Silljé 1 collaboration

Daniel Röshammar 1 collaboration

Anders Himmelmann 1 collaboration

Dominick J Angiolillo 1 collaboration

Robert F Storey 1 collaboration

Paul A Gurbel 1 collaboration

Marc P Bonaca 1 collaboration

Mikael Boberg 1 collaboration

Joel Tarning 1 collaboration

Angela Äbelö 1 collaboration

Michael Ashton 1 collaboration

Rasmus Jansson-Löfmark 1 collaboration

Mohammad Niazi 1 collaboration

Anders Berggren 1 collaboration

Matthew M Heeney 1 collaboration

Marielle Andersson 1 collaboration

Jessie Githanga 1 collaboration

Baba Inusa 1 collaboration

Alan D Michelson 1 collaboration

Anders R Berggren 1 collaboration

Carina Leandersson 1 collaboration

Anja Ekdahl 1 collaboration

Thomas Antonsson 1 collaboration

Johan Sundell 1 collaboration

Kristina Westerlund 1 collaboration

Tord Inghardt 1 collaboration

Chandrali Bhattacharya 1 collaboration

Jingjing Yan 1 collaboration

Linda C Andersson 1 collaboration

Marta Pelay-Gimeno 1 collaboration

Wouter H J Vaes 1 collaboration

Rianne A F de Ligt 1 collaboration

Somasekhara R Menakuru 1 collaboration

Bo Lindmark 1 collaboration

Kristin Samuelsson 1 collaboration

Jane Knöchel 1 collaboration

Sharan Sidhu 1 collaboration

Maria Lagerstrom-Fermer 1 collaboration

Erik Michaëlsson 1 collaboration

Magnus Kjaer 1 collaboration

Muir Russell 1 collaboration

David Han 1 collaboration

Li-Ming Gan 1 collaboration

Daniel Pettersen 1 collaboration

Johan Broddefalk 1 collaboration

Hans Emtenäs 1 collaboration

Martin A Hayes 1 collaboration

Malin Lemurell 1 collaboration

Marianne Swanson 1 collaboration

Johan Ulander 1 collaboration

Annika Westin Eriksson 1 collaboration

Kenneth Granberg 1 collaboration

Alleyn T Plowright 1 collaboration

Igor Shamovsky 1 collaboration

Anita Dellsèn 1 collaboration

Monica Sundqvist 1 collaboration

Mats Någård 1 collaboration

Banu Kaya 1 collaboration

Videlis Nduba 1 collaboration

Christer Gottfridsson 1 collaboration

Martin Rensfeldt 1 collaboration