Casey E Romanoski

Affiliations

The Department of Cellular and Molecular Medicine, The University of Arizona, Tucson, AZ 85721, USA.
The Clinical Translational Sciences Graduate Program, The University of Arizona, Tucson, AZ, 85721, USA.
Asthma and Airway Disease Research Center, The University of Arizona, Tucson, AZ, 85721, USA.

Publications (21)

Single cell 'omic profiles of human aortic endothelial cells

bioRxiv : the preprint server for biology

Avec: Maria L Adelus , Jiacheng Ding , Binh T Tran , Austin C Conklin , Anna K Golebiewski , Lindsey K Stolze , Michael B Whalen , Darren A Cusanovich , Casey E Romanoski

Unraveling the Role of Sex in Endothelial Cell Dysfunction: Evidence From Lineage Tracing Mice and Cultured Cells.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Junchul Shin , Junyoung Hong , Jonnelle Edwards-Glenn , Irene Krukovets , Svyatoslav Tkachenko , Maria L Adelus , Casey E Romanoski , Sanjay Rajagopalan , Eugene Podrez , Tatiana V Byzova , Olga Stenina-Adongravi , Olga A Cherepanova

Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2.

Nature metabolism

Avec: Karthickeyan Chella Krishnan , Laurent Vergnes , Rebeca Acín-Pérez , Linsey Stiles , Michael Shum , Lijiang Ma , Etienne Mouisel , Calvin Pan , Timothy M Moore , Miklós Péterfy , Casey E Romanoski , Karen Reue , Johan L M Björkegren , Markku Laakso , Marc Liesa , Aldons J Lusis

Integrative analysis of liver-specific non-coding regulatory SNPs associated with the risk of coronary artery disease.

American journal of human genetics

Avec: Ilakya Selvarajan , Anu Toropainen , Kristina M Garske , Maykel López Rodríguez , Arthur Ko , Zong Miao , Dorota Kaminska , Kadri Õunap , Tiit Örd , Aarthi Ravindran , Oscar H Liu , Pierre R Moreau , Ashik Jawahar Deen , Ville Männistö , Calvin Pan , Anna-Liisa Levonen , Aldons J Lusis , Sami Heikkinen , Casey E Romanoski , Jussi Pihlajamäki , Päivi Pajukanta , Minna U Kaikkonen

Genome-wide analysis identifies novel susceptibility loci for myocardial infarction.

European heart journal

Avec: Jaana A Hartiala , Yi Han , Qiong Jia , James R Hilser , Pin Huang , Janet Gukasyan , William S Schwartzman , Zhiheng Cai , Subarna Biswas , David-Alexandre Trégouët , Nicholas L Smith , Auteur inconnu , Auteur inconnu , Auteur inconnu , Marcus Seldin , Calvin Pan , Margarete Mehrabian , Aldons J Lusis , Peter Bazeley , Yan V Sun , Chang Liu , Arshed A Quyyumi , Markus Scholz , Joachim Thiery , Graciela E Delgado , Marcus E Kleber , Winfried März , Laurence J Howe , Folkert W Asselbergs , Marion van Vugt , Georgios J Vlachojannis , Riyaz S Patel , Leo-Pekka Lyytikäinen , Mika Kähönen , Terho Lehtimäki , Tuomo V M Nieminen , Pekka Kuukasjärvi , Jari O Laurikka , Xuling Chang , Chew-Kiat Heng , Rong Jiang , William E Kraus , Elizabeth R Hauser , Jane F Ferguson , Muredach P Reilly , Kaoru Ito , Satoshi Koyama , Yoichiro Kamatani , Issei Komuro , Auteur inconnu , Lindsey K Stolze , Casey E Romanoski , Mohammad Daud Khan , Adam W Turner , Clint L Miller , Redouane Aherrahrou , Mete Civelek , Lijiang Ma , Johan L M Björkegren , S Ram Kumar , W H Wilson Tang , Stanley L Hazen , Hooman Allayee

TNFα increases the degradation of pyruvate dehydrogenase kinase 4 by the Lon protease to support proinflammatory genes.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Nabil E Boutagy , Joseph W Fowler , Kariona A Grabinska , Rebecca Cardone , Qiushi Sun , Kyla R Vazquez , Michael B Whalen , Xiaolong Zhu , Raja Chakraborty , Kathleen A Martin , Michael Simons , Casey E Romanoski , Richard G Kibbey , William C Sessa

Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning.

Cell reports

Avec: Adam W Watson , Adam D Grant , Sara S Parker , Samantha Hill , Michael B Whalen , Jayati Chakrabarti , Michael W Harman , Mackenzie R Roman , Brittany L Forte , Cody C Gowan , Raúl Castro-Portuguez , Lindsey K Stolze , Christian Franck , Darren A Cusanovich , Yana Zavros , Megha Padi , Casey E Romanoski , Ghassan Mouneimne

Functional noncoding SNPs in human endothelial cells fine-map vascular trait associations.

Genome research

Avec: Anu Toropainen , Lindsey K Stolze , Tiit Örd , Michael B Whalen , Paula Martí Torrell , Verena M Link , Minna U Kaikkonen , Casey E Romanoski

SREBP2 regulates the endothelial response to cytokines via direct transcriptional activation of KLF6.

Journal of lipid research

Avec: Joseph Wayne M Fowler , Nabil E Boutagy , Rong Zhang , Daiki Horikami , Michael B Whalen , Casey E Romanoski , William C Sessa

Transcriptomic and epigenetic mechanisms underlying myeloid diversity in the lung.

Nature immunology

Avec: Eniko Sajti , Verena M Link , Zhengyu Ouyang , Nathanael J Spann , Emma Westin , Casey E Romanoski , Gregory J Fonseca , Lawrence S Prince , Christopher K Glass

Systems Genetics in Human Endothelial Cells Identifies Non-coding Variants Modifying Enhancers, Expression, and Complex Disease Traits.

American journal of human genetics

Avec: Lindsey K Stolze , Austin C Conklin , Michael B Whalen , Maykel López Rodríguez , Kadri Õunap , Ilakya Selvarajan , Anu Toropainen , Tiit Örd , Jin Li , Anna Eshghi , Alice E Solomon , Yun Fang , Minna U Kaikkonen , Casey E Romanoski

An upstream enhancer regulates

Journal of lipid research

Avec: Christopher M Allan , Patrick J Heizer , Yiping Tu , Norma P Sandoval , Rachel S Jung , Jazmin E Morales , Eniko Sajti , Ty D Troutman , Thomas L Saunders , Darren A Cusanovich , Anne P Beigneux , Casey E Romanoski , Loren G Fong , Stephen G Young

Systematic analysis of naturally occurring insertions and deletions that alter transcription factor spacing identifies tolerant and sensitive transcription factor pairs.

eLife

Avec: Zeyang Shen , Rick Z Li , Thomas A Prohaska , Marten A Hoeksema , Nathan J Spann , Jenhan Tao , Gregory J Fonseca , Thomas Le , Lindsey K Stolze , Mashito Sakai , Casey E Romanoski , Christopher K Glass

Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood.

Nature communications

Avec: Sokratis Kariotis , Emmanuel Jammeh , Emilia M Swietlik , Josephine A Pickworth , Christopher J Rhodes , Pablo Otero , John Wharton , James Iremonger , Mark J Dunning , Divya Pandya , Thomas S Mascarenhas , Niamh Errington , A A Roger Thompson , Casey E Romanoski , Franz Rischard , Joe G N Garcia , Jason X-J Yuan , Tae-Hwi Schwantes An , Ankit A Desai , Gerry Coghlan , Jim Lordan , Paul A Corris , Luke S Howard , Robin Condliffe , David G Kiely , Colin Church , Joanna Pepke-Zaba , Mark Toshner , Stephen Wort , Stefan Gräf , Nicholas W Morrell , Martin R Wilkins , Allan Lawrie , Dennis Wang , Auteur inconnu

Transcriptomic profiles in pulmonary arterial hypertension associate with disease severity and identify novel candidate genes.

Pulmonary circulation

Avec: Casey E Romanoski , Xinshuai Qi , Shreya Sangam , Rebecca R Vanderpool , Robert S Stearman , Austin Conklin , Manuel Gonzalez-Garay , Franz Rischard , Ramon J Ayon , Jian Wang , Tatum Simonson , Aleksandra Babicheva , Yinan Shi , Haiyang Tang , Ayako Makino , Yogendra Kanthi , Mark W Geraci , Joe G N Garcia , Jason X-J Yuan , Ankit A Desai

Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci.

Circulation research

Avec: Tiit Örd , Kadri Õunap , Lindsey K Stolze , Redouane Aherrahrou , Valtteri Nurminen , Anu Toropainen , Ilakya Selvarajan , Tapio Lönnberg , Einari Aavik , Seppo Ylä-Herttuala , Mete Civelek , Casey E Romanoski , Minna U Kaikkonen

Meta-Analysis of Smooth Muscle Lineage Transcriptomes in Atherosclerosis and Their Relationships to In Vitro Models.

Immunometabolism

Avec: Austin C Conklin , Hitoo Nishi , Florencia Schlamp , Tiit Örd , Kadri Õunap , Minna U Kaikkonen , Edward A Fisher , Casey E Romanoski

Transcriptional drifts associated with environmental changes in endothelial cells.

eLife

Avec: Yalda Afshar , Feyiang Ma , Austin Quach , Anhyo Jeong , Hannah L Sunshine , Vanessa Freitas , Yasaman Jami-Alahmadi , Raphael Helaers , Xinmin Li , Matteo Pellegrini , James A Wohlschlegel , Casey E Romanoski , Miikka Vikkula , M Luisa Iruela-Arispe

Mechanosensitive super-enhancers regulate genes linked to atherosclerosis in endothelial cells.

The Journal of cell biology

Avec: Jin Li , Jiayu Zhu , Olivia Gray , Débora R Sobreira , David Wu , Ru-Ting Huang , Bernadette Miao , Noboru J Sakabe , Matthew D Krause , Minna U Kaikkonen , Casey E Romanoski , Marcelo A Nobrega , Yun Fang

Single-cell 'omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesions ex vivo reveal heterogeneity of endothelial subtype and response to activating perturbations.

eLife

Avec: Maria L Adelus , Jiacheng Ding , Binh T Tran , Austin C Conklin , Anna K Golebiewski , Lindsey K Stolze , Michael B Whalen , Darren A Cusanovich , Casey E Romanoski

Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Ilakya Selvarajan , Miika Kiema , Ru-Ting Huang , Jin Li , Jiayu Zhu , Petri Pölönen , Tiit Örd , Kadri Õunap , Mehvash Godiwala , Anna Kathryn Golebiewski , Aarthi Ravindran , Kiira Mäklin , Anu Toropainen , Lindsey K Stolze , Maximiliano Arce , Peetra U Magnusson , Stephen White , Casey E Romanoski , Merja Heinäniemi , Johanna P Laakkonen , Yun Fang , Minna Kaikkonen-Määttä

Réseau de co-auteurs

Lindsey K Stolze 9 collaborations

Michael B Whalen 7 collaborations

Tiit Örd 6 collaborations

Minna U Kaikkonen 6 collaborations

Anu Toropainen 5 collaborations

Kadri Õunap 5 collaborations

None None 5 collaborations

Austin C Conklin 4 collaborations

Darren A Cusanovich 4 collaborations

Ilakya Selvarajan 4 collaborations

Maria L Adelus 3 collaborations

Calvin Pan 3 collaborations

Aldons J Lusis 3 collaborations

Jin Li 3 collaborations

Yun Fang 3 collaborations

Jiacheng Ding 2 collaborations

Binh T Tran 2 collaborations

Anna K Golebiewski 2 collaborations

Lijiang Ma 2 collaborations

Johan L M Björkegren 2 collaborations

Maykel López Rodríguez 2 collaborations

Aarthi Ravindran 2 collaborations

Redouane Aherrahrou 2 collaborations

Mete Civelek 2 collaborations

Nabil E Boutagy 2 collaborations

William C Sessa 2 collaborations

Verena M Link 2 collaborations

Eniko Sajti 2 collaborations

Gregory J Fonseca 2 collaborations

Christopher K Glass 2 collaborations

Franz Rischard 2 collaborations

Joe G N Garcia 2 collaborations

Jason X-J Yuan 2 collaborations

Ankit A Desai 2 collaborations

Jiayu Zhu 2 collaborations

Ru-Ting Huang 2 collaborations

Junchul Shin 1 collaboration

Junyoung Hong 1 collaboration

Jonnelle Edwards-Glenn 1 collaboration

Irene Krukovets 1 collaboration

Svyatoslav Tkachenko 1 collaboration

Sanjay Rajagopalan 1 collaboration

Eugene Podrez 1 collaboration

Tatiana V Byzova 1 collaboration

Olga Stenina-Adongravi 1 collaboration

Olga A Cherepanova 1 collaboration

Karthickeyan Chella Krishnan 1 collaboration

Laurent Vergnes 1 collaboration

Rebeca Acín-Pérez 1 collaboration

Linsey Stiles 1 collaboration

Michael Shum 1 collaboration

Etienne Mouisel 1 collaboration

Timothy M Moore 1 collaboration

Miklós Péterfy 1 collaboration

Karen Reue 1 collaboration

Markku Laakso 1 collaboration

Marc Liesa 1 collaboration

Kristina M Garske 1 collaboration

Arthur Ko 1 collaboration

Zong Miao 1 collaboration

Dorota Kaminska 1 collaboration

Oscar H Liu 1 collaboration

Pierre R Moreau 1 collaboration

Ashik Jawahar Deen 1 collaboration

Ville Männistö 1 collaboration

Anna-Liisa Levonen 1 collaboration

Sami Heikkinen 1 collaboration

Jussi Pihlajamäki 1 collaboration

Päivi Pajukanta 1 collaboration

Jaana A Hartiala 1 collaboration

Yi Han 1 collaboration

Qiong Jia 1 collaboration

James R Hilser 1 collaboration

Pin Huang 1 collaboration

Janet Gukasyan 1 collaboration

William S Schwartzman 1 collaboration

Zhiheng Cai 1 collaboration

Subarna Biswas 1 collaboration

David-Alexandre Trégouët 1 collaboration

Nicholas L Smith 1 collaboration

Marcus Seldin 1 collaboration

Margarete Mehrabian 1 collaboration

Peter Bazeley 1 collaboration

Yan V Sun 1 collaboration

Chang Liu 1 collaboration

Arshed A Quyyumi 1 collaboration

Markus Scholz 1 collaboration

Joachim Thiery 1 collaboration

Graciela E Delgado 1 collaboration

Marcus E Kleber 1 collaboration

Winfried März 1 collaboration

Laurence J Howe 1 collaboration

Folkert W Asselbergs 1 collaboration

Marion van Vugt 1 collaboration

Georgios J Vlachojannis 1 collaboration

Riyaz S Patel 1 collaboration

Leo-Pekka Lyytikäinen 1 collaboration

Mika Kähönen 1 collaboration

Terho Lehtimäki 1 collaboration

Tuomo V M Nieminen 1 collaboration

Pekka Kuukasjärvi 1 collaboration

Jari O Laurikka 1 collaboration

Xuling Chang 1 collaboration

Chew-Kiat Heng 1 collaboration

Rong Jiang 1 collaboration

William E Kraus 1 collaboration

Elizabeth R Hauser 1 collaboration

Jane F Ferguson 1 collaboration

Muredach P Reilly 1 collaboration

Kaoru Ito 1 collaboration

Satoshi Koyama 1 collaboration

Yoichiro Kamatani 1 collaboration

Issei Komuro 1 collaboration

Mohammad Daud Khan 1 collaboration

Adam W Turner 1 collaboration

Clint L Miller 1 collaboration

S Ram Kumar 1 collaboration

W H Wilson Tang 1 collaboration

Stanley L Hazen 1 collaboration

Hooman Allayee 1 collaboration

Joseph W Fowler 1 collaboration

Kariona A Grabinska 1 collaboration

Rebecca Cardone 1 collaboration

Qiushi Sun 1 collaboration

Kyla R Vazquez 1 collaboration

Xiaolong Zhu 1 collaboration

Raja Chakraborty 1 collaboration

Kathleen A Martin 1 collaboration

Michael Simons 1 collaboration

Richard G Kibbey 1 collaboration

Adam W Watson 1 collaboration

Adam D Grant 1 collaboration

Sara S Parker 1 collaboration

Samantha Hill 1 collaboration

Jayati Chakrabarti 1 collaboration

Michael W Harman 1 collaboration

Mackenzie R Roman 1 collaboration

Brittany L Forte 1 collaboration

Cody C Gowan 1 collaboration

Raúl Castro-Portuguez 1 collaboration

Christian Franck 1 collaboration

Yana Zavros 1 collaboration

Megha Padi 1 collaboration

Ghassan Mouneimne 1 collaboration

Paula Martí Torrell 1 collaboration

Joseph Wayne M Fowler 1 collaboration

Rong Zhang 1 collaboration

Daiki Horikami 1 collaboration

Zhengyu Ouyang 1 collaboration

Nathanael J Spann 1 collaboration

Emma Westin 1 collaboration

Lawrence S Prince 1 collaboration

Anna Eshghi 1 collaboration

Alice E Solomon 1 collaboration

Christopher M Allan 1 collaboration

Patrick J Heizer 1 collaboration

Yiping Tu 1 collaboration

Norma P Sandoval 1 collaboration

Rachel S Jung 1 collaboration

Jazmin E Morales 1 collaboration

Ty D Troutman 1 collaboration

Thomas L Saunders 1 collaboration

Anne P Beigneux 1 collaboration

Loren G Fong 1 collaboration

Stephen G Young 1 collaboration

Zeyang Shen 1 collaboration

Rick Z Li 1 collaboration

Thomas A Prohaska 1 collaboration

Marten A Hoeksema 1 collaboration

Nathan J Spann 1 collaboration

Jenhan Tao 1 collaboration

Thomas Le 1 collaboration

Mashito Sakai 1 collaboration

Sokratis Kariotis 1 collaboration

Emmanuel Jammeh 1 collaboration

Emilia M Swietlik 1 collaboration

Josephine A Pickworth 1 collaboration

Christopher J Rhodes 1 collaboration

Pablo Otero 1 collaboration

John Wharton 1 collaboration

James Iremonger 1 collaboration

Mark J Dunning 1 collaboration

Divya Pandya 1 collaboration

Thomas S Mascarenhas 1 collaboration

Niamh Errington 1 collaboration

A A Roger Thompson 1 collaboration

Tae-Hwi Schwantes An 1 collaboration

Gerry Coghlan 1 collaboration

Jim Lordan 1 collaboration

Paul A Corris 1 collaboration

Luke S Howard 1 collaboration

Robin Condliffe 1 collaboration

David G Kiely 1 collaboration

Colin Church 1 collaboration

Joanna Pepke-Zaba 1 collaboration

Mark Toshner 1 collaboration

Stephen Wort 1 collaboration

Stefan Gräf 1 collaboration

Nicholas W Morrell 1 collaboration

Martin R Wilkins 1 collaboration

Allan Lawrie 1 collaboration

Dennis Wang 1 collaboration

Xinshuai Qi 1 collaboration

Shreya Sangam 1 collaboration

Rebecca R Vanderpool 1 collaboration

Robert S Stearman 1 collaboration

Austin Conklin 1 collaboration

Manuel Gonzalez-Garay 1 collaboration

Ramon J Ayon 1 collaboration

Jian Wang 1 collaboration

Tatum Simonson 1 collaboration

Aleksandra Babicheva 1 collaboration

Yinan Shi 1 collaboration

Haiyang Tang 1 collaboration

Ayako Makino 1 collaboration

Yogendra Kanthi 1 collaboration

Mark W Geraci 1 collaboration

Valtteri Nurminen 1 collaboration

Tapio Lönnberg 1 collaboration

Einari Aavik 1 collaboration

Seppo Ylä-Herttuala 1 collaboration

Hitoo Nishi 1 collaboration

Florencia Schlamp 1 collaboration

Edward A Fisher 1 collaboration

Yalda Afshar 1 collaboration

Feyiang Ma 1 collaboration

Austin Quach 1 collaboration

Anhyo Jeong 1 collaboration

Hannah L Sunshine 1 collaboration

Vanessa Freitas 1 collaboration

Yasaman Jami-Alahmadi 1 collaboration

Raphael Helaers 1 collaboration

Xinmin Li 1 collaboration

Matteo Pellegrini 1 collaboration

James A Wohlschlegel 1 collaboration

Miikka Vikkula 1 collaboration

M Luisa Iruela-Arispe 1 collaboration

Olivia Gray 1 collaboration

Débora R Sobreira 1 collaboration

David Wu 1 collaboration

Bernadette Miao 1 collaboration

Noboru J Sakabe 1 collaboration

Matthew D Krause 1 collaboration

Marcelo A Nobrega 1 collaboration

Miika Kiema 1 collaboration

Petri Pölönen 1 collaboration

Mehvash Godiwala 1 collaboration

Anna Kathryn Golebiewski 1 collaboration

Kiira Mäklin 1 collaboration

Maximiliano Arce 1 collaboration

Peetra U Magnusson 1 collaboration

Stephen White 1 collaboration

Merja Heinäniemi 1 collaboration

Johanna P Laakkonen 1 collaboration

Minna Kaikkonen-Määttä 1 collaboration