Conny Gysemans

Affiliations

Clinical and Experimental Endocrinology (CEE), Department of Chronic Diseases, Metabolism and Ageing, Campus Gasthuisberg O&N 1, Katholieke Universiteit Leuven (KU Leuven), Leuven, Belgium.

Publications (29)

Intestinal Delivery of Proinsulin and IL-10 via

Frontiers in immunology

Avec: Dana P Cook , João Paulo Monteiro Carvalho Mori Cunha , Pieter-Jan Martens , Gabriele Sassi , Francesca Mancarella , Giuliana Ventriglia , Guido Sebastiani , An-Sofie Vanherwegen , Mark A Atkinson , Karolien Van Huynegem , Lothar Steidler , Silvia Caluwaerts , Pieter Rottiers , Luc Teyton , Francesco Dotta , Conny Gysemans , Chantal Mathieu

Macrophages are metabolically heterogeneous within the tumor microenvironment.

Cell reports

Avec: Xenia Geeraerts , Juan Fernández-Garcia , Felix J Hartmann , Kyra E de Goede , Liesbet Martens , Yvon Elkrim , Ayla Debraekeleer , Benoit Stijlemans , Anke Vandekeere , Gianmarco Rinaldi , Riet De Rycke , Mélanie Planque , Dorien Broekaert , Elisa Meinster , Emile Clappaert , Pauline Bardet , Aleksandar Murgaski , Conny Gysemans , Frank Aboubakar Nana , Yvan Saeys , Sean C Bendall , Damya Laoui , Jan Van den Bossche , Sarah-Maria Fendt , Jo A Van Ginderachter

Challenges for labeling and longitudinal tracking of adoptively transferred autoreactive T lymphocytes in an experimental type-1 diabetes model.

Magma (New York, N.Y.)

Avec: Shweta Saini , Hannelie Korf , Sayuan Liang , Rein Verbeke , Bella Manshian , Koen Raemdonck , Ine Lentacker , Conny Gysemans , Stefaan C De Smedt , Uwe Himmelreich

Vitamin D-modulated dendritic cells delay lethal graft-versus-host disease through induction of regulatory T cells.

The Journal of steroid biochemistry and molecular biology

Avec: An-Sofie Vanherwegen , Dana Paulina Cook , Gabriela Bomfim Ferreira , Conny Gysemans , Chantal Mathieu

HAMSAB diet ameliorates dysfunctional signaling in pancreatic islets in autoimmune diabetes.

iScience

Avec: Valerie Vandenbempt , Sema Elif Eski , Manoja K Brahma , Ao Li , Javier Negueruela , Ylke Bruggeman , Stéphane Demine , Peng Xiao , Alessandra K Cardozo , Nicolas Baeyens , Luciano G Martelotto , Sumeet Pal Singh , Eliana Mariño , Conny Gysemans , Esteban N Gurzov

Preventing type 1 diabetes in late-stage pre-diabetic NOD mice with insulin: A central role for alum as adjuvant.

Frontiers in endocrinology

Avec: Pieter-Jan Martens , Darcy Ellis , Ylke Bruggeman , Marijke Viaene , Jos Laureys , Luc Teyton , Chantal Mathieu , Conny Gysemans

NET Proteome in Established Type 1 Diabetes Is Enriched in Metabolic Proteins.

Cells

Avec: Samal Bissenova , Darcy Ellis , Aïsha Callebaut , Guy Eelen , Rita Derua , Mijke Buitinga , Chantal Mathieu , Conny Gysemans , Lut Overbergh

Data on inflammatory cytokines and pathways involved in clearance of

Data in brief

Avec: Jef Serré , Carolien Mathyssen , Tom Tanjeko Ajime , Hannelie Korf , Karen Maes , Nele Heulens , Conny Gysemans , Chantal Mathieu , Bart Vanaudenaerde , Wim Janssens , Ghislaine Gayan-Ramirez

100 YEARS OF INSULIN: Arresting or curing type 1 diabetes: an elusive goal, but closing the gap.

The Journal of endocrinology

Avec: Pieter-Jan Martens , Conny Gysemans , Chantal Mathieu

SARS-CoV-2 Receptor Angiotensin I-Converting Enzyme Type 2 (ACE2) Is Expressed in Human Pancreatic

Frontiers in endocrinology

Avec: Daniela Fignani , Giada Licata , Noemi Brusco , Laura Nigi , Giuseppina E Grieco , Lorella Marselli , Lut Overbergh , Conny Gysemans , Maikel L Colli , Piero Marchetti , Chantal Mathieu , Decio L Eizirik , Guido Sebastiani , Francesco Dotta

Pancreatic Alpha-Cells Contribute Together With Beta-Cells to CXCL10 Expression in Type 1 Diabetes.

Frontiers in endocrinology

Avec: Laura Nigi , Noemi Brusco , Giuseppina E Grieco , Giada Licata , Lars Krogvold , Lorella Marselli , Conny Gysemans , Lut Overbergh , Piero Marchetti , Chantal Mathieu , Knut Dahl Jørgensen , Guido Sebastiani , Francesco Dotta

High-Throughput Analysis of Neutrophil Extracellular Trap Levels in Subtypes of People with Type 1 Diabetes.

Biology

Avec: Samal Bissenova , Mijke Buitinga , Markus Boesch , Hannelie Korf , Kristina Casteels , An Teunkens , Chantal Mathieu , Conny Gysemans

Footprint of pancreas infiltrating and circulating immune cells throughout type 1 diabetes development.

Frontiers in endocrinology

Avec: Ylke Bruggeman , Pieter-Jan Martens , Gabriele Sassi , Marijke Viaene , Clive H Wasserfall , Chantal Mathieu , Conny Gysemans

Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization.

Nature neuroscience

Avec: Ana Rita Pombo Antunes , Isabelle Scheyltjens , Francesca Lodi , Julie Messiaen , Asier Antoranz , Johnny Duerinck , Daliya Kancheva , Liesbet Martens , Karen De Vlaminck , Hannah Van Hove , Signe Schmidt Kjølner Hansen , Francesca Maria Bosisio , Koen Van der Borght , Steven De Vleeschouwer , Raf Sciot , Luc Bouwens , Michiel Verfaillie , Niels Vandamme , Roosmarijn E Vandenbroucke , Olivier De Wever , Yvan Saeys , Martin Guilliams , Conny Gysemans , Bart Neyns , Frederik De Smet , Diether Lambrechts , Jo A Van Ginderachter , Kiavash Movahedi

Age-Dependent Changes in Glucose Homeostasis in Male Deiodinase Type 2 Knockout Zebrafish.

Endocrinology

Avec: Anne M Houbrechts , An Beckers , Pieter Vancamp , Jurgen Sergeys , Conny Gysemans , Chantal Mathieu , Veerle M Darras

PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic β-Cells in Autoimmune Diabetes.

Diabetes

Avec: Bernat Elvira , Valerie Vandenbempt , Julia Bauzá-Martinez , Raphaël Crutzen , Javier Negueruela , Hazem Ibrahim , Matthew L Winder , Manoja K Brahma , Beata Vekeriotaite , Pieter-Jan Martens , Sumeet Pal Singh , Fernando Rossello , Pascale Lybaert , Timo Otonkoski , Conny Gysemans , Wei Wu , Esteban N Gurzov

High Serum Vitamin D Concentrations, Induced

Frontiers in immunology

Avec: Pieter-Jan Martens , Javier Centelles-Lodeiro , Darcy Ellis , Dana Paulina Cook , Gabriele Sassi , Lieve Verlinden , Annemieke Verstuyf , Jeroen Raes , Chantal Mathieu , Conny Gysemans

Fluorine MR Imaging Probes Dynamic Migratory Profiles of Perfluorocarbon-Loaded Dendritic Cells After Streptozotocin-Induced Inflammation.

Molecular imaging and biology

Avec: Shweta Saini , An-Sofie Vanherwegen , Sayuan Liang , Rein Verbeke , Hannelie Korf , Ine Lentacker , Stefaan C De Smedt , Conny Gysemans , Uwe Himmelreich

Neutrophils in autoimmunity: when the hero becomes the villain.

Clinical and experimental immunology

Avec: Samal Bissenova , Darcy Ellis , Chantal Mathieu , Conny Gysemans

A Plasma miR-193b-365 Signature Combined With Age and Glycemic Status Predicts Response to Lactococcus lactis-Based Antigen-Specific Immunotherapy in New-Onset Type 1 Diabetes.

Diabetes

Avec: Gabriele Sassi , Giada Licata , Giuliana Ventriglia , Amber Wouters , Pierre Lemaitre , Ruth Seurinck , Alessia Mori , Giuseppina Emanuela Grieco , Samal Bissenova , Darcy Ellis , Silvia Caluwaerts , Pieter Rottiers , Niels Vandamme , Chantal Mathieu , Francesco Dotta , Conny Gysemans , Guido Sebastiani

Vitamin D's Effect on Immune Function.

Nutrients

Avec: Pieter-Jan Martens , Conny Gysemans , Annemieke Verstuyf , And Chantal Mathieu

miR-409-3p is reduced in plasma and islet immune infiltrates of NOD diabetic mice and is differentially expressed in people with type 1 diabetes.

Diabetologia

Avec: Giuliana Ventriglia , Francesca Mancarella , Guido Sebastiani , Dana P Cook , Roberto Mallone , Chantal Mathieu , Conny Gysemans , Francesco Dotta

Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells.

Cell death & disease

Avec: Saurabh Vig , Mijke Buitinga , Dieter Rondas , Inne Crèvecoeur , Marc van Zandvoort , Etienne Waelkens , Decio L Eizirik , Conny Gysemans , Pieter Baatsen , Chantal Mathieu , Lut Overbergh

Airway infection with Nontypeable Haemophilus influenzae is more rapidly eradicated in vitamin D deficient mice.

The Journal of steroid biochemistry and molecular biology

Avec: Jef Serré , Carolien Mathyssen , Tom Tanjeko Ajime , Hannelie Korf , Karen Maes , Nele Heulens , Conny Gysemans , Chantal Mathieu , Bart Vanaudenaerde , Wim Janssens , Ghislaine Gayan-Ramirez

Vitamin D controls the capacity of human dendritic cells to induce functional regulatory T cells by regulation of glucose metabolism.

The Journal of steroid biochemistry and molecular biology

Avec: An-Sofie Vanherwegen , Guy Eelen , Gabriela Bomfim Ferreira , Bart Ghesquière , Dana Paulina Cook , Tanja Nikolic , Bart Roep , Peter Carmeliet , Sucheta Telang , Chantal Mathieu , Conny Gysemans

Pro-Inflammatory Cytokines Induce Insulin and Glucagon Double Positive Human Islet Cells That Are Resistant to Apoptosis.

Biomolecules

Avec: Marta Tesi , Marco Bugliani , Gianmarco Ferri , Mara Suleiman , Carmela De Luca , Emanuele Bosi , Matilde Masini , Vincenzo De Tata , Conny Gysemans , Francesco Cardarelli , Miriam Cnop , Decio L Eizirik , Piero Marchetti , Lorella Marselli

Longitudinal In Vivo Assessment of Host-Microbe Interactions in a Murine Model of Pulmonary Aspergillosis.

iScience

Avec: Shweta Saini , Jennifer Poelmans , Hannelie Korf , James L Dooley , Sayuan Liang , Bella B Manshian , Rein Verbeke , Stefaan J Soenen , Greetje Vande Velde , Ine Lentacker , Katrien Lagrou , Adrian Liston , Conny Gysemans , Stefaan C De Smedt , Uwe Himmelreich

Protocol to analyze circulating small non-coding RNAs by high-throughput RNA sequencing from human plasma samples.

STAR protocols

Avec: Giuseppina E Grieco , Guido Sebastiani , Daniela Fignani , Noemi Brusco , Laura Nigi , Caterina Formichi , Giada Licata , Marco Bruttini , Romina D'Aurizio , Chantal Mathieu , Conny Gysemans , Francesco Dotta

Effects of repeated infections with non-typeable Haemophilus influenzae on lung in vitamin D deficient and smoking mice.

Respiratory research

Avec: Jef Serré , Ajime Tom Tanjeko , Carolien Mathyssen , Tobias Heigl , Annelore Sacreas , Dana Paulina Cook , Erik Verbeken , Karen Maes , Jan Verhaegen , Charles Pilette , Jeroen Vanoirbeek , Conny Gysemans , Chantal Mathieu , Bart Vanaudenaerde , Wim Janssens , Ghislaine Gayan-Ramirez

Réseau de co-auteurs

Chantal Mathieu 20 collaborations

Pieter-Jan Martens 7 collaborations

Guido Sebastiani 6 collaborations

Francesco Dotta 6 collaborations

Hannelie Korf 6 collaborations

Darcy Ellis 5 collaborations

Gabriele Sassi 4 collaborations

An-Sofie Vanherwegen 4 collaborations

Dana Paulina Cook 4 collaborations

Samal Bissenova 4 collaborations

Lut Overbergh 4 collaborations

Giada Licata 4 collaborations

Giuliana Ventriglia 3 collaborations

Shweta Saini 3 collaborations

Sayuan Liang 3 collaborations

Rein Verbeke 3 collaborations

Ine Lentacker 3 collaborations

Stefaan C De Smedt 3 collaborations

Uwe Himmelreich 3 collaborations

Ylke Bruggeman 3 collaborations

Mijke Buitinga 3 collaborations

Jef Serré 3 collaborations

Carolien Mathyssen 3 collaborations

Karen Maes 3 collaborations

Bart Vanaudenaerde 3 collaborations

Wim Janssens 3 collaborations

Ghislaine Gayan-Ramirez 3 collaborations

Noemi Brusco 3 collaborations

Laura Nigi 3 collaborations

Giuseppina E Grieco 3 collaborations

Lorella Marselli 3 collaborations

Piero Marchetti 3 collaborations

Decio L Eizirik 3 collaborations

Dana P Cook 2 collaborations

Francesca Mancarella 2 collaborations

Silvia Caluwaerts 2 collaborations

Pieter Rottiers 2 collaborations

Luc Teyton 2 collaborations

Liesbet Martens 2 collaborations

Yvan Saeys 2 collaborations

Jo A Van Ginderachter 2 collaborations

Gabriela Bomfim Ferreira 2 collaborations

Valerie Vandenbempt 2 collaborations

Manoja K Brahma 2 collaborations

Javier Negueruela 2 collaborations

Sumeet Pal Singh 2 collaborations

Esteban N Gurzov 2 collaborations

Marijke Viaene 2 collaborations

Guy Eelen 2 collaborations

Tom Tanjeko Ajime 2 collaborations

Nele Heulens 2 collaborations

Daniela Fignani 2 collaborations

Niels Vandamme 2 collaborations

Annemieke Verstuyf 2 collaborations

João Paulo Monteiro Carvalho Mori Cunha 1 collaboration

Mark A Atkinson 1 collaboration

Karolien Van Huynegem 1 collaboration

Lothar Steidler 1 collaboration

Xenia Geeraerts 1 collaboration

Juan Fernández-Garcia 1 collaboration

Felix J Hartmann 1 collaboration

Kyra E de Goede 1 collaboration

Yvon Elkrim 1 collaboration

Ayla Debraekeleer 1 collaboration

Benoit Stijlemans 1 collaboration

Anke Vandekeere 1 collaboration

Gianmarco Rinaldi 1 collaboration

Riet De Rycke 1 collaboration

Mélanie Planque 1 collaboration

Dorien Broekaert 1 collaboration

Elisa Meinster 1 collaboration

Emile Clappaert 1 collaboration

Pauline Bardet 1 collaboration

Aleksandar Murgaski 1 collaboration

Frank Aboubakar Nana 1 collaboration

Sean C Bendall 1 collaboration

Damya Laoui 1 collaboration

Jan Van den Bossche 1 collaboration

Sarah-Maria Fendt 1 collaboration

Bella Manshian 1 collaboration

Koen Raemdonck 1 collaboration

Sema Elif Eski 1 collaboration

Ao Li 1 collaboration

Stéphane Demine 1 collaboration

Peng Xiao 1 collaboration

Alessandra K Cardozo 1 collaboration

Nicolas Baeyens 1 collaboration

Luciano G Martelotto 1 collaboration

Eliana Mariño 1 collaboration

Jos Laureys 1 collaboration

Aïsha Callebaut 1 collaboration

Rita Derua 1 collaboration

Maikel L Colli 1 collaboration

Lars Krogvold 1 collaboration

Knut Dahl Jørgensen 1 collaboration

Markus Boesch 1 collaboration

Kristina Casteels 1 collaboration

An Teunkens 1 collaboration

Clive H Wasserfall 1 collaboration

Ana Rita Pombo Antunes 1 collaboration

Isabelle Scheyltjens 1 collaboration

Francesca Lodi 1 collaboration

Julie Messiaen 1 collaboration

Asier Antoranz 1 collaboration

Johnny Duerinck 1 collaboration

Daliya Kancheva 1 collaboration

Karen De Vlaminck 1 collaboration

Hannah Van Hove 1 collaboration

Signe Schmidt Kjølner Hansen 1 collaboration

Francesca Maria Bosisio 1 collaboration

Koen Van der Borght 1 collaboration

Steven De Vleeschouwer 1 collaboration

Raf Sciot 1 collaboration

Luc Bouwens 1 collaboration

Michiel Verfaillie 1 collaboration

Roosmarijn E Vandenbroucke 1 collaboration

Olivier De Wever 1 collaboration

Martin Guilliams 1 collaboration

Bart Neyns 1 collaboration

Frederik De Smet 1 collaboration

Diether Lambrechts 1 collaboration

Kiavash Movahedi 1 collaboration

Anne M Houbrechts 1 collaboration

An Beckers 1 collaboration

Pieter Vancamp 1 collaboration

Jurgen Sergeys 1 collaboration

Veerle M Darras 1 collaboration

Bernat Elvira 1 collaboration

Julia Bauzá-Martinez 1 collaboration

Raphaël Crutzen 1 collaboration

Hazem Ibrahim 1 collaboration

Matthew L Winder 1 collaboration

Beata Vekeriotaite 1 collaboration

Fernando Rossello 1 collaboration

Pascale Lybaert 1 collaboration

Timo Otonkoski 1 collaboration

Wei Wu 1 collaboration

Javier Centelles-Lodeiro 1 collaboration

Lieve Verlinden 1 collaboration

Jeroen Raes 1 collaboration

Amber Wouters 1 collaboration

Pierre Lemaitre 1 collaboration

Ruth Seurinck 1 collaboration

Alessia Mori 1 collaboration

Giuseppina Emanuela Grieco 1 collaboration

And Chantal Mathieu 1 collaboration

Roberto Mallone 1 collaboration

Saurabh Vig 1 collaboration

Dieter Rondas 1 collaboration

Inne Crèvecoeur 1 collaboration

Marc van Zandvoort 1 collaboration

Etienne Waelkens 1 collaboration

Pieter Baatsen 1 collaboration

Bart Ghesquière 1 collaboration

Tanja Nikolic 1 collaboration

Bart Roep 1 collaboration

Peter Carmeliet 1 collaboration

Sucheta Telang 1 collaboration

Marta Tesi 1 collaboration

Marco Bugliani 1 collaboration

Gianmarco Ferri 1 collaboration

Mara Suleiman 1 collaboration

Carmela De Luca 1 collaboration

Emanuele Bosi 1 collaboration

Matilde Masini 1 collaboration

Vincenzo De Tata 1 collaboration

Francesco Cardarelli 1 collaboration

Miriam Cnop 1 collaboration

Jennifer Poelmans 1 collaboration

James L Dooley 1 collaboration

Bella B Manshian 1 collaboration

Stefaan J Soenen 1 collaboration

Greetje Vande Velde 1 collaboration

Katrien Lagrou 1 collaboration

Adrian Liston 1 collaboration

Caterina Formichi 1 collaboration

Marco Bruttini 1 collaboration

Romina D'Aurizio 1 collaboration

Ajime Tom Tanjeko 1 collaboration

Tobias Heigl 1 collaboration

Annelore Sacreas 1 collaboration

Erik Verbeken 1 collaboration

Jan Verhaegen 1 collaboration

Charles Pilette 1 collaboration

Jeroen Vanoirbeek 1 collaboration