Isabelle Scheyltjens

Affiliations

Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium.
Myeloid Cell Immunology Lab, VIB Center for Inflammation Research, Brussels, Belgium.
Laboratory of Molecular and Cellular Therapy, Department of Biomedical Sciences, Vrije Universiteit Brussel, Brussels, Belgium.

Publications (18)

Imaging of Glioblastoma Tumor-Associated Myeloid Cells Using Nanobodies Targeting Signal Regulatory Protein Alpha.

Frontiers in immunology

Avec: Karen De Vlaminck , Ema Romão , Janik Puttemans , Ana Rita Pombo Antunes , Daliya Kancheva , Isabelle Scheyltjens , Jo A Van Ginderachter , Serge Muyldermans , Nick Devoogdt , Kiavash Movahedi , Geert Raes

c-Fos expression following context conditioning and deep brain stimulation in the bed nucleus of the stria terminalis in rats.

Scientific reports

Avec: Kelly Luyck , Isabelle Scheyltjens , Bart Nuttin , Lutgarde Arckens , Laura Luyten

Interleukin-10 Prevents Pathological Microglia Hyperactivation following Peripheral Endotoxin Challenge.

Immunity

Avec: Anat Shemer , Isabelle Scheyltjens , Gal Ronit Frumer , Jung-Seok Kim , Jonathan Grozovski , Serkalem Ayanaw , Bareket Dassa , Hannah Van Hove , Louise Chappell-Maor , Sigalit Boura-Halfon , Dena Leshkowitz , Werner Mueller , Nicola Maggio , Kiavash Movahedi , Steffen Jung

Infection history imprints prolonged changes to the epigenome, transcriptome and function of Kupffer cells.

Journal of hepatology

Avec: Mohamed Amer Musrati , Benoit Stijlemans , Abdulkader Azouz , Daliya Kancheva , Sarah Mesbahi , Eva Hadadi , Els Lebegge , Leen Ali , Karen De Vlaminck , Isabelle Scheyltjens , Niels Vandamme , Maida Zivalj , Naela Assaf , Yvon Elkrim , Ilham Ahmidi , Camille Huart , Mohamed Lamkanfi , Martin Guilliams , Patrick De Baetselier , Stanislas Goriely , Kiavash Movahedi , Jo A Van Ginderachter

Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization.

Nature neuroscience

Avec: Ana Rita Pombo Antunes , Isabelle Scheyltjens , Francesca Lodi , Julie Messiaen , Asier Antoranz , Johnny Duerinck , Daliya Kancheva , Liesbet Martens , Karen De Vlaminck , Hannah Van Hove , Signe Schmidt Kjølner Hansen , Francesca Maria Bosisio , Koen Van der Borght , Steven De Vleeschouwer , Raf Sciot , Luc Bouwens , Michiel Verfaillie , Niels Vandamme , Roosmarijn E Vandenbroucke , Olivier De Wever , Yvan Saeys , Martin Guilliams , Conny Gysemans , Bart Neyns , Frederik De Smet , Diether Lambrechts , Jo A Van Ginderachter , Kiavash Movahedi

Single-cell RNA and protein profiling of immune cells from the mouse brain and its border tissues.

Nature protocols

Avec: Isabelle Scheyltjens , Hannah Van Hove , Karen De Vlaminck , Daliya Kancheva , Jonathan Bastos , Mónica Vara-Pérez , Ana Rita Pombo Antunes , Liesbet Martens , Charlotte L Scott , Jo A Van Ginderachter , Yvan Saeys , Martin Guilliams , Niels Vandamme , Kiavash Movahedi

Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neurons.

Acta neuropathologica communications

Avec: Lien Andries , Daliya Kancheva , Luca Masin , Isabelle Scheyltjens , Hannah Van Hove , Karen De Vlaminck , Steven Bergmans , Marie Claes , Lies De Groef , Lieve Moons , Kiavash Movahedi

Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease.

Frontiers in immunology

Avec: Sahana Srinivasan , Daliya Kancheva , Sofie De Ren , Takashi Saito , Maude Jans , Fleur Boone , Charysse Vandendriessche , Ine Paesmans , Hervé Maurin , Roosmarijn E Vandenbroucke , Esther Hoste , Sofie Voet , Isabelle Scheyltjens , Benjamin Pavie , Saskia Lippens , Marius Schwabenland , Marco Prinz , Takaomi Saido , Astrid Bottelbergs , Kiavash Movahedi , Mohamed Lamkanfi , Geert van Loo

Identifying the variables that drive tamoxifen-independent CreERT2 recombination: Implications for microglial fate mapping and gene deletions.

European journal of immunology

Avec: Hannah Van Hove , Ana Rita Pombo Antunes , Karen De Vlaminck , Isabelle Scheyltjens , Jo A Van Ginderachter , Kiavash Movahedi

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment.

Nature neuroscience

Avec: Hannah Van Hove , Liesbet Martens , Isabelle Scheyltjens , Karen De Vlaminck , Ana Rita Pombo Antunes , Sofie De Prijck , Niels Vandamme , Sebastiaan De Schepper , Gert Van Isterdael , Charlotte L Scott , Jeroen Aerts , Geert Berx , Guy E Boeckxstaens , Roosmarijn E Vandenbroucke , Lars Vereecke , Diederik Moechars , Martin Guilliams , Jo A Van Ginderachter , Yvan Saeys , Kiavash Movahedi

A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages.

Immunity

Avec: Jung-Seok Kim , Masha Kolesnikov , Shany Peled-Hajaj , Isabelle Scheyltjens , Yuan Xia , Sebastien Trzebanski , Zhana Haimon , Anat Shemer , Alisa Lubart , Hannah Van Hove , Louise Chappell-Maor , Sigalit Boura-Halfon , Kiavash Movahedi , Pablo Blinder , Steffen Jung

Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies.

eLife

Avec: Ana Rita Pombo Antunes , Isabelle Scheyltjens , Johnny Duerinck , Bart Neyns , Kiavash Movahedi , Jo A Van Ginderachter

Optogenetic Stimulation of the Superior Colliculus Confers Retinal Neuroprotection in a Mouse Glaucoma Model.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Avec: Emiel Geeraerts , Marie Claes , Eline Dekeyster , Manuel Salinas-Navarro , Lies De Groef , Chris Van den Haute , Isabelle Scheyltjens , Veerle Baekelandt , Lutgarde Arckens , Lieve Moons

Therapeutic depletion of CCR8

Journal for immunotherapy of cancer

Avec: Helena Van Damme , Bruno Dombrecht , Máté Kiss , Heleen Roose , Elizabeth Allen , Eva Van Overmeire , Daliya Kancheva , Liesbet Martens , Aleksandar Murgaski , Pauline Madeleine Rachel Bardet , Gillian Blancke , Maude Jans , Evangelia Bolli , Maria Solange Martins , Yvon Elkrim , James Dooley , Louis Boon , Julia Katharina Schwarze , Frank Tacke , Kiavash Movahedi , Niels Vandamme , Bart Neyns , Sebahat Ocak , Isabelle Scheyltjens , Lars Vereecke , Frank Aboubakar Nana , Pascal Merchiers , Damya Laoui , Jo Agnes Van Ginderachter

CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia.

Acta neuropathologica communications

Avec: Chritica Lodder , Isabelle Scheyltjens , Ilie Cosmin Stancu , Pablo Botella Lucena , Manuel Gutiérrez de Ravé , Sarah Vanherle , Tim Vanmierlo , Niels Cremers , Hannah Vanrusselt , Bert Brône , Bernard Hanseeuw , Jean-Noël Octave , Astrid Bottelbergs , Kiavash Movahedi , Ilse Dewachter

Comparative analysis of antibody- and lipid-based multiplexing methods for single-cell RNA-seq.

Genome biology

Avec: Viacheslav Mylka , Irina Matetovici , Suresh Poovathingal , Jeroen Aerts , Niels Vandamme , Ruth Seurinck , Kevin Verstaen , Gert Hulselmans , Silvie Van den Hoecke , Isabelle Scheyltjens , Kiavash Movahedi , Hans Wils , Joke Reumers , Jeroen Van Houdt , Stein Aerts , Yvan Saeys

Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation.

Immunity

Avec: Karen De Vlaminck , Hannah Van Hove , Daliya Kancheva , Isabelle Scheyltjens , Ana Rita Pombo Antunes , Jonathan Bastos , Monica Vara-Perez , Leen Ali , Myrthe Mampay , Lauren Deneyer , Juliana Fabiani Miranda , Ruiyao Cai , Luc Bouwens , Dimitri De Bundel , Guy Caljon , Benoît Stijlemans , Ann Massie , Jo A Van Ginderachter , Roosmarijn E Vandenbroucke , Kiavash Movahedi

Junctional adhesion molecule-A is dispensable for myeloid cell recruitment and diversification in the tumor microenvironment.

Frontiers in immunology

Avec: Máté Kiss , Els Lebegge , Aleksandar Murgaski , Helena Van Damme , Daliya Kancheva , Jan Brughmans , Isabelle Scheyltjens , Ali Talebi , Robin Maximilian Awad , Yvon Elkrim , Pauline M R Bardet , Sana M Arnouk , Cleo Goyvaerts , Johan Swinnen , Frank Aboubakar Nana , Jo A Van Ginderachter , Damya Laoui

Réseau de co-auteurs

Kiavash Movahedi 15 collaborations

Daliya Kancheva 9 collaborations

Jo A Van Ginderachter 9 collaborations

Karen De Vlaminck 8 collaborations

Hannah Van Hove 8 collaborations

Ana Rita Pombo Antunes 7 collaborations

Niels Vandamme 6 collaborations

Martin Guilliams 4 collaborations

Liesbet Martens 4 collaborations

Roosmarijn E Vandenbroucke 4 collaborations

Yvan Saeys 4 collaborations

Yvon Elkrim 3 collaborations

Bart Neyns 3 collaborations

Lutgarde Arckens 2 collaborations

Anat Shemer 2 collaborations

Jung-Seok Kim 2 collaborations

Louise Chappell-Maor 2 collaborations

Sigalit Boura-Halfon 2 collaborations

Steffen Jung 2 collaborations

Els Lebegge 2 collaborations

Leen Ali 2 collaborations

Mohamed Lamkanfi 2 collaborations

Johnny Duerinck 2 collaborations

Luc Bouwens 2 collaborations

Jonathan Bastos 2 collaborations

Charlotte L Scott 2 collaborations

Marie Claes 2 collaborations

Lies De Groef 2 collaborations

Lieve Moons 2 collaborations

Maude Jans 2 collaborations

Astrid Bottelbergs 2 collaborations

Jeroen Aerts 2 collaborations

Lars Vereecke 2 collaborations

Helena Van Damme 2 collaborations

Máté Kiss 2 collaborations

Aleksandar Murgaski 2 collaborations

Frank Aboubakar Nana 2 collaborations

Damya Laoui 2 collaborations

Ema Romão 1 collaboration

Janik Puttemans 1 collaboration

Serge Muyldermans 1 collaboration

Nick Devoogdt 1 collaboration

Geert Raes 1 collaboration

Kelly Luyck 1 collaboration

Bart Nuttin 1 collaboration

Laura Luyten 1 collaboration

Gal Ronit Frumer 1 collaboration

Jonathan Grozovski 1 collaboration

Serkalem Ayanaw 1 collaboration

Bareket Dassa 1 collaboration

Dena Leshkowitz 1 collaboration

Werner Mueller 1 collaboration

Nicola Maggio 1 collaboration

Mohamed Amer Musrati 1 collaboration

Benoit Stijlemans 1 collaboration

Abdulkader Azouz 1 collaboration

Sarah Mesbahi 1 collaboration

Eva Hadadi 1 collaboration

Maida Zivalj 1 collaboration

Naela Assaf 1 collaboration

Ilham Ahmidi 1 collaboration

Camille Huart 1 collaboration

Patrick De Baetselier 1 collaboration

Stanislas Goriely 1 collaboration

Francesca Lodi 1 collaboration

Julie Messiaen 1 collaboration

Asier Antoranz 1 collaboration

Signe Schmidt Kjølner Hansen 1 collaboration

Francesca Maria Bosisio 1 collaboration

Koen Van der Borght 1 collaboration

Steven De Vleeschouwer 1 collaboration

Raf Sciot 1 collaboration

Michiel Verfaillie 1 collaboration

Olivier De Wever 1 collaboration

Conny Gysemans 1 collaboration

Frederik De Smet 1 collaboration

Diether Lambrechts 1 collaboration

Mónica Vara-Pérez 1 collaboration

Lien Andries 1 collaboration

Luca Masin 1 collaboration

Steven Bergmans 1 collaboration

Sahana Srinivasan 1 collaboration

Sofie De Ren 1 collaboration

Takashi Saito 1 collaboration

Fleur Boone 1 collaboration

Charysse Vandendriessche 1 collaboration

Ine Paesmans 1 collaboration

Hervé Maurin 1 collaboration

Esther Hoste 1 collaboration

Sofie Voet 1 collaboration

Benjamin Pavie 1 collaboration

Saskia Lippens 1 collaboration

Marius Schwabenland 1 collaboration

Marco Prinz 1 collaboration

Takaomi Saido 1 collaboration

Geert van Loo 1 collaboration

Sofie De Prijck 1 collaboration

Sebastiaan De Schepper 1 collaboration

Gert Van Isterdael 1 collaboration

Geert Berx 1 collaboration

Guy E Boeckxstaens 1 collaboration

Diederik Moechars 1 collaboration

Masha Kolesnikov 1 collaboration

Shany Peled-Hajaj 1 collaboration

Yuan Xia 1 collaboration

Sebastien Trzebanski 1 collaboration

Zhana Haimon 1 collaboration

Alisa Lubart 1 collaboration

Pablo Blinder 1 collaboration

Emiel Geeraerts 1 collaboration

Eline Dekeyster 1 collaboration

Manuel Salinas-Navarro 1 collaboration

Chris Van den Haute 1 collaboration

Veerle Baekelandt 1 collaboration

Bruno Dombrecht 1 collaboration

Heleen Roose 1 collaboration

Elizabeth Allen 1 collaboration

Eva Van Overmeire 1 collaboration

Pauline Madeleine Rachel Bardet 1 collaboration

Gillian Blancke 1 collaboration

Evangelia Bolli 1 collaboration

Maria Solange Martins 1 collaboration

James Dooley 1 collaboration

Louis Boon 1 collaboration

Julia Katharina Schwarze 1 collaboration

Frank Tacke 1 collaboration

Sebahat Ocak 1 collaboration

Pascal Merchiers 1 collaboration

Jo Agnes Van Ginderachter 1 collaboration

Chritica Lodder 1 collaboration

Ilie Cosmin Stancu 1 collaboration

Pablo Botella Lucena 1 collaboration

Manuel Gutiérrez de Ravé 1 collaboration

Sarah Vanherle 1 collaboration

Tim Vanmierlo 1 collaboration

Niels Cremers 1 collaboration

Hannah Vanrusselt 1 collaboration

Bert Brône 1 collaboration

Bernard Hanseeuw 1 collaboration

Jean-Noël Octave 1 collaboration

Ilse Dewachter 1 collaboration

Viacheslav Mylka 1 collaboration

Irina Matetovici 1 collaboration

Suresh Poovathingal 1 collaboration

Ruth Seurinck 1 collaboration

Kevin Verstaen 1 collaboration

Gert Hulselmans 1 collaboration

Silvie Van den Hoecke 1 collaboration

Hans Wils 1 collaboration

Joke Reumers 1 collaboration

Jeroen Van Houdt 1 collaboration

Stein Aerts 1 collaboration

Monica Vara-Perez 1 collaboration

Myrthe Mampay 1 collaboration

Lauren Deneyer 1 collaboration

Juliana Fabiani Miranda 1 collaboration

Ruiyao Cai 1 collaboration

Dimitri De Bundel 1 collaboration

Guy Caljon 1 collaboration

Benoît Stijlemans 1 collaboration

Ann Massie 1 collaboration

Jan Brughmans 1 collaboration

Ali Talebi 1 collaboration

Robin Maximilian Awad 1 collaboration

Pauline M R Bardet 1 collaboration

Sana M Arnouk 1 collaboration

Cleo Goyvaerts 1 collaboration

Johan Swinnen 1 collaboration