D Langleben

Affiliations
  • Department of Medicine, McGill University, Montreal, Canada; Division of Cardiology, Jewish General Hospital, Montreal, Canada; Lady Davis Institute for Medical Research, Montreal, Canada.

Publications (29)

Efficacy and safety of riociguat in combination therapy for patients with pulmonary arterial hypertension (PATENT studies).

Pulmonary circulation
Avec: Hossein-Ardeschir Ghofrani , Ekkehard Grünig , Pavel Jansa , David Langleben , Stephan Rosenkranz , Ioana R Preston , Franck Rahaghi , Namita Sood , Dennis Busse , Christian Meier , Marc Humbert

Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry.

Respiratory medicine
Avec: Hossein-Ardeschir Ghofrani , Miguel-Angel Gomez Sanchez , Marc Humbert , David Pittrow , Gérald Simonneau , Henning Gall , Ekkehard Grünig , Hans Klose , Michael Halank , David Langleben , Repke J Snijder , Pilar Escribano Subias , Lisa M Mielniczuk , Tobias J Lange , Jean-Luc Vachiéry , Hubert Wirtz , Douglas S Helmersen , Iraklis Tsangaris , Joan A Barberá , Joanna Pepke-Zaba , Anco Boonstra , Stephan Rosenkranz , Silvia Ulrich , Regina Steringer-Mascherbauer , Marion Delcroix , Pavel Jansa , Iveta Šimková , George Giannakoulas , Jens Klotsche , Evgenia Williams , Christian Meier , Marius M Hoeper , Auteur inconnu

Riociguat treatment in patients with pulmonary arterial hypertension: Final safety data from the EXPERT registry.

Respiratory medicine
Avec: Marius M Hoeper , Miguel-Angel Gomez Sanchez , Marc Humbert , David Pittrow , Gérald Simonneau , Henning Gall , Ekkehard Grünig , Hans Klose , Michael Halank , David Langleben , Repke J Snijder , Pilar Escribano Subias , Lisa M Mielniczuk , Tobias J Lange , Jean-Luc Vachiéry , Hubert Wirtz , Douglas S Helmersen , Iraklis Tsangaris , Joan A Barberà , Joanna Pepke-Zaba , Anco Boonstra , Stephan Rosenkranz , Silvia Ulrich , Regina Steringer-Mascherbauer , Marion Delcroix , Pavel Jansa , Iveta Šimková , George Giannakoulas , Jens Klotsche , Evgenia Williams , Christian Meier , Hossein-Ardeschir Ghofrani , Auteur inconnu

Transpulmonary Plasma Endothelin-1 Arterial:Venous Ratio Differentiates Survivors from Non-Survivors in Critically Ill Patients with COVID-19-Induced Acute Respiratory Distress Syndrome.

International journal of molecular sciences
Avec: Alice G Vassiliou , Anastasia Roumpaki , Chrysi Keskinidou , Nikolaos Athanasiou , Stamatios Tsipilis , Edison Jahaj , Charikleia S Vrettou , Vassiliki Giannopoulou , Asimenia Halioti , Georgios Ferentinos , Ioanna Dimopoulou , Anastasia Kotanidou , David Langleben , Stylianos E Orfanos

Knockdown of bone morphogenetic protein type II receptor leads to decreased aquaporin 1 expression and function in human pulmonary microvascular endothelial cells.

Canadian journal of physiology and pharmacology
Avec: Alice G Vassiliou , Chrysi Keskinidou , Anastasia Kotanidou , Frantzeska Frantzeskaki , Ioanna Dimopoulou , David Langleben , Stylianos E Orfanos

Pulmonary capillary surface area in supine exercising humans: demonstration of vascular recruitment.

American journal of physiology. Lung cellular and molecular physiology
Avec: David Langleben , Stylianos E Orfanos , Michele Giovinazzo , Robert D Schlesinger , Robert Naeije , Benjamin D Fox , Ali O Abualsaud , Fay Blenkhorn , Lawrence G Rudski , John D Catravas

Results of an Expert Consensus Survey on the Treatment of Pulmonary Arterial Hypertension With Oral Prostacyclin Pathway Agents.

Chest
Avec: Vallerie V McLaughlin , Richard Channick , Teresa De Marco , Harrison W Farber , Sean Gaine , Nazzareno Galié , Richard A Krasuski , Ioana Preston , Rogerio Souza , J Gerry Coghlan , Robert P Frantz , Anna Hemnes , Nick H Kim , Irene M Lang , David Langleben , Mengtao Li , Olivier Sitbon , Victor Tapson , Adaani Frost

Slow-release naltrexone implant versus oral naltrexone for improving treatment outcomes in people with HIV who are addicted to opioids: a double-blind, placebo-controlled, randomised trial.

The lancet. HIV
Avec: Evgeny Krupitsky , Elena Blokhina , Edwin Zvartau , Elena Verbitskaya , Dmitri Lioznov , Tatiana Yaroslavtseva , Vladimir Palatkin , Marina Vetrova , Natalia Bushara , Andrei Burakov , Dmitri Masalov , Olga Mamontova , Daniel Langleben , Sabrina Poole , Robert Gross , George Woody

Pathophysiology of the right ventricle and of the pulmonary circulation in pulmonary hypertension: an update.

The European respiratory journal
Avec: Anton Vonk Noordegraaf , Kelly Marie Chin , François Haddad , Paul M Hassoun , Anna R Hemnes , Susan Roberta Hopkins , Steven Mark Kawut , David Langleben , Joost Lumens , Robert Naeije

The Role of Thyroid Disorders, Obesity, Diabetes Mellitus and Estrogen Exposure as Potential Modifiers for Pulmonary Hypertension.

Journal of clinical medicine
Avec: Eleni Vrigkou , Evangeline Vassilatou , Effrosyni Dima , David Langleben , Anastasia Kotanidou , Marinella Tzanela

Application of REVEAL Lite 2 and COMPERA 2.0 risk scores to patients with pulmonary arterial hypertension switching to riociguat in the REPLACE study.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Avec: Raymond L Benza , Gérald Simonneau , Hossein-Ardeschir Ghofrani , Paul A Corris , David Langleben , Stephan Rosenkranz , R James White , Chin-Chang Cheng , Frederico T A Figueiredo Campos , Hyung-Kwan Kim , Rogerio Souza , Mikyung Chang , Claudia Rahner , Christian Meier , Marius M Hoeper

Pulmonary capillary recruitment and distention in mammalian lungs: species similarities.

European respiratory review : an official journal of the European Respiratory Society
Avec: David Langleben , Benjamin D Fox , Stylianos E Orfanos , Michele Giovinazzo , John D Catravas

Effects of Modulating BMP9, BMPR2, and AQP1 on BMP Signaling in Human Pulmonary Microvascular Endothelial Cells.

International journal of molecular sciences
Avec: Nikolaos S Lotsios , Chrysi Keskinidou , Ioanna Dimopoulou , Anastasia Kotanidou , David Langleben , Stylianos E Orfanos , Alice G Vassiliou

Management of pulmonary hypertension in special conditions.

The European respiratory journal
Avec: Ioana R Preston , Luke S Howard , David Langleben , Mona Lichtblau , Tomas Pulido , Rogerio Souza , Karen M Olsson

Riociguat: Clinical research and evolving role in therapy.

British journal of clinical pharmacology
Avec: James R Klinger , Murali M Chakinala , David Langleben , Stephan Rosenkranz , Olivier Sitbon

Canadian Cardiovascular Society/Canadian Thoracic Society Position Statement on Pulmonary Hypertension.

The Canadian journal of cardiology
Avec: Naushad Hirani , Nathan W Brunner , Ali Kapasi , George Chandy , Lawrence Rudski , Ian Paterson , David Langleben , Sanjay Mehta , Lisa Mielniczuk , Auteur inconnu

Effect of riociguat on right ventricular function in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Avec: Raymond L Benza , Hossein-Ardeschir Ghofrani , Ekkehard Grünig , Marius M Hoeper , Pavel Jansa , Zhi-Cheng Jing , Nick H Kim , David Langleben , Gérald Simonneau , Chen Wang , Dennis Busse , Christian Meier , Stefano Ghio

Oral anticoagulants (NOAC and VKA) in chronic thromboembolic pulmonary hypertension.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Avec: Marc Humbert , Gérald Simonneau , David Pittrow , Marion Delcroix , Joanna Pepke-Zaba , David Langleben , Lisa M Mielniczuk , Pilar Escribano Subias , Repke J Snijder , Joan A Barberà , Jens Klotsche , Christian Meier , Marius M Hoeper

Safety and efficacy of riociguat in patients with pulmonary arterial hypertension and cardiometabolic comorbidities: Data from interventional clinical trials.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Avec: Stephan Rosenkranz , Hossein-Ardeschir Ghofrani , Marius M Hoeper , David Langleben , Sara Hegab , Claudia Rahner , Jean-François Richard , Vallerie V McLaughlin

Safety and efficacy of direct oral anticoagulants in patients with chronic thromboembolic pulmonary hypertension.

Thrombosis research
Avec: Ilham Benzidia , Chantal Robitaille , Ali Abualsaud , Laura McDonald , Lyda Lesenko , Jean-François Morin , David Langleben , Susan R Kahn , Andrew Hirsch

Safety and efficacy of rodatristat ethyl for the treatment of pulmonary arterial hypertension (ELEVATE-2): a dose-ranging, randomised, multicentre, phase 2b trial.

The Lancet. Respiratory medicine
Avec: Olivier Sitbon , Andris Skride , Jeremy Feldman , Sandeep Sahay , Oksana A Shlobin , Vallerie McLaughlin , Hossein-Ardeschir Ghofrani , David Langleben , Ed Parsley , Gwyn D'Souza , Tonya Marmon , Watiri Kamau-Kelley , Renee Jones , Ravi Grewal , Steve Wring , Michelle Palacios , Himanshu Naik , Jill Denning , Howard M Lazarus , Marc Humbert

Impact of saline loading at cardiac catheterization on the classification and management of patients evaluated for pulmonary hypertension.

International journal of cardiology
Avec: Nima Moghaddam , John R Swiston , Jason Weatherald , Lisa Mielniczuk , Ali Kapasi , Nathan Hambly , David Langleben , Nathan W Brunner

An evidence-based strategy to screen for pulmonary arterial hypertension in systemic sclerosis.

Seminars in arthritis and rheumatism
Avec: T Semalulu , L Rudski , T Huynh , D Langleben , M Wang , Auteur inconnu , M J Fritzler , J Pope , M Baron , M Hudson

Identifying potential parameters associated with response to switching from a PDE5i to riociguat in RESPITE.

International journal of cardiology
Avec: Raymond L Benza , Paul A Corris , James R Klinger , David Langleben , Robert Naeije , Gérald Simonneau , Hossein-Ardeschir Ghofrani , Pavel Jansa , Stephan Rosenkranz , Laura Scelsi , Thenappan Thenappan , Amresh Raina , Christian Meier , Dennis Busse , Marius M Hoeper

Switching to riociguat versus maintenance therapy with phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension (REPLACE): a multicentre, open-label, randomised controlled trial.

The Lancet. Respiratory medicine
Avec: Marius M Hoeper , Hikmet Al-Hiti , Raymond L Benza , Sung-A Chang , Paul A Corris , J Simon R Gibbs , Ekkehard Grünig , Pavel Jansa , James R Klinger , David Langleben , Vallerie V McLaughlin , Gisela M B Meyer , Jaquelina Ota-Arakaki , Andrew J Peacock , Tomás Pulido , Stephan Rosenkranz , Carmine Dario Vizza , Anton Vonk-Noordegraaf , R James White , Mikyung Chang , Frank Kleinjung , Christian Meier , Karen Paraschin , Hossein Ardeschir Ghofrani , Gérald Simonneau , Auteur inconnu

Assessment of the REPLACE study composite endpoint in riociguat-treated patients in the PATENT study.

Pulmonary circulation
Avec: Gérald Simonneau , Hossein-Ardeschir Ghofrani , Paul A Corris , Stephan Rosenkranz , Ekkehard Grünig , Jim White , Vallerie V McLaughlin , David Langleben , Christian Meier , Dennis Busse , Frank Kleinjung , Raymond L Benza

The Insomnia-Addiction Positive Feedback Loop: Role of the Orexin System.

Frontiers of neurology and neuroscience
Avec: Jennifer E Fragale , Morgan H James , Jorge A Avila , Andrea M Spaeth , R Nisha Aurora , Daniel Langleben , Gary Aston-Jones

The Paradox of Pulmonary Vascular Resistance: Restoration of Pulmonary Capillary Recruitment as a

Journal of clinical medicine
Avec: David Langleben , Stylianos E Orfanos , Benjamin D Fox , Nathan Messas , Michele Giovinazzo , John D Catravas

Riociguat and the right ventricle in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.

European respiratory review : an official journal of the European Respiratory Society
Avec: Raymond L Benza , David Langleben , Anna R Hemnes , Anton Vonk Noordegraaf , Stephan Rosenkranz , Thenappan Thenappan , Paul M Hassoun , Ioana R Preston , Stefano Ghio , Roberto Badagliacca , Carmine D Vizza , Irene M Lang , Christian Meier , Ekkehard Grünig

Réseau de co-auteurs

David Langleben 26 collaborations
Stephan Rosenkranz 10 collaborations
Christian Meier 10 collaborations
Hossein-Ardeschir Ghofrani 9 collaborations
Gérald Simonneau 8 collaborations
Marius M Hoeper 8 collaborations
Ekkehard Grünig 7 collaborations
Pavel Jansa 6 collaborations
Stylianos E Orfanos 6 collaborations
Raymond L Benza 6 collaborations
Marc Humbert 5 collaborations
None None 5 collaborations
Dennis Busse 4 collaborations
Anastasia Kotanidou 4 collaborations
Vallerie V McLaughlin 4 collaborations
Paul A Corris 4 collaborations
Ioana R Preston 3 collaborations
David Pittrow 3 collaborations
Repke J Snijder 3 collaborations
Pilar Escribano Subias 3 collaborations
Lisa M Mielniczuk 3 collaborations
Joanna Pepke-Zaba 3 collaborations
Marion Delcroix 3 collaborations
Jens Klotsche 3 collaborations
Alice G Vassiliou 3 collaborations
Chrysi Keskinidou 3 collaborations
Ioanna Dimopoulou 3 collaborations
Michele Giovinazzo 3 collaborations
Robert Naeije 3 collaborations
Benjamin D Fox 3 collaborations
John D Catravas 3 collaborations
Rogerio Souza 3 collaborations
Olivier Sitbon 3 collaborations
James R Klinger 3 collaborations
Miguel-Angel Gomez Sanchez 2 collaborations
Henning Gall 2 collaborations
Hans Klose 2 collaborations
Michael Halank 2 collaborations
Tobias J Lange 2 collaborations
Jean-Luc Vachiéry 2 collaborations
Hubert Wirtz 2 collaborations
Douglas S Helmersen 2 collaborations
Iraklis Tsangaris 2 collaborations
Anco Boonstra 2 collaborations
Silvia Ulrich 2 collaborations
Regina Steringer-Mascherbauer 2 collaborations
Iveta Šimková 2 collaborations
George Giannakoulas 2 collaborations
Evgenia Williams 2 collaborations
Joan A Barberà 2 collaborations
Nick H Kim 2 collaborations
Irene M Lang 2 collaborations
Daniel Langleben 2 collaborations
Anton Vonk Noordegraaf 2 collaborations
Paul M Hassoun 2 collaborations
Anna R Hemnes 2 collaborations
R James White 2 collaborations
Mikyung Chang 2 collaborations
Claudia Rahner 2 collaborations
Nathan W Brunner 2 collaborations
Ali Kapasi 2 collaborations
Lisa Mielniczuk 2 collaborations
Stefano Ghio 2 collaborations
Thenappan Thenappan 2 collaborations
Frank Kleinjung 2 collaborations
Franck Rahaghi 1 collaboration
Namita Sood 1 collaboration
Joan A Barberá 1 collaboration
Anastasia Roumpaki 1 collaboration
Nikolaos Athanasiou 1 collaboration
Stamatios Tsipilis 1 collaboration
Edison Jahaj 1 collaboration
Charikleia S Vrettou 1 collaboration
Vassiliki Giannopoulou 1 collaboration
Asimenia Halioti 1 collaboration
Georgios Ferentinos 1 collaboration
Frantzeska Frantzeskaki 1 collaboration
Robert D Schlesinger 1 collaboration
Ali O Abualsaud 1 collaboration
Fay Blenkhorn 1 collaboration
Lawrence G Rudski 1 collaboration
Richard Channick 1 collaboration
Teresa De Marco 1 collaboration
Harrison W Farber 1 collaboration
Sean Gaine 1 collaboration
Nazzareno Galié 1 collaboration
Richard A Krasuski 1 collaboration
Ioana Preston 1 collaboration
J Gerry Coghlan 1 collaboration
Robert P Frantz 1 collaboration
Anna Hemnes 1 collaboration
Mengtao Li 1 collaboration
Victor Tapson 1 collaboration
Adaani Frost 1 collaboration
Evgeny Krupitsky 1 collaboration
Elena Blokhina 1 collaboration
Edwin Zvartau 1 collaboration
Elena Verbitskaya 1 collaboration
Dmitri Lioznov 1 collaboration
Tatiana Yaroslavtseva 1 collaboration
Vladimir Palatkin 1 collaboration
Marina Vetrova 1 collaboration
Natalia Bushara 1 collaboration
Andrei Burakov 1 collaboration
Dmitri Masalov 1 collaboration
Olga Mamontova 1 collaboration
Sabrina Poole 1 collaboration
Robert Gross 1 collaboration
George Woody 1 collaboration
Kelly Marie Chin 1 collaboration
François Haddad 1 collaboration
Susan Roberta Hopkins 1 collaboration
Steven Mark Kawut 1 collaboration
Joost Lumens 1 collaboration
Eleni Vrigkou 1 collaboration
Evangeline Vassilatou 1 collaboration
Effrosyni Dima 1 collaboration
Marinella Tzanela 1 collaboration
Chin-Chang Cheng 1 collaboration
Frederico T A Figueiredo Campos 1 collaboration
Hyung-Kwan Kim 1 collaboration
Nikolaos S Lotsios 1 collaboration
Luke S Howard 1 collaboration
Mona Lichtblau 1 collaboration
Tomas Pulido 1 collaboration
Karen M Olsson 1 collaboration
Murali M Chakinala 1 collaboration
Naushad Hirani 1 collaboration
George Chandy 1 collaboration
Lawrence Rudski 1 collaboration
Ian Paterson 1 collaboration
Sanjay Mehta 1 collaboration
Zhi-Cheng Jing 1 collaboration
Chen Wang 1 collaboration
Sara Hegab 1 collaboration
Jean-François Richard 1 collaboration
Ilham Benzidia 1 collaboration
Chantal Robitaille 1 collaboration
Ali Abualsaud 1 collaboration
Laura McDonald 1 collaboration
Lyda Lesenko 1 collaboration
Jean-François Morin 1 collaboration
Susan R Kahn 1 collaboration
Andrew Hirsch 1 collaboration
Andris Skride 1 collaboration
Jeremy Feldman 1 collaboration
Sandeep Sahay 1 collaboration
Oksana A Shlobin 1 collaboration
Vallerie McLaughlin 1 collaboration
Ed Parsley 1 collaboration
Gwyn D'Souza 1 collaboration
Tonya Marmon 1 collaboration
Watiri Kamau-Kelley 1 collaboration
Renee Jones 1 collaboration
Ravi Grewal 1 collaboration
Steve Wring 1 collaboration
Michelle Palacios 1 collaboration
Himanshu Naik 1 collaboration
Jill Denning 1 collaboration
Howard M Lazarus 1 collaboration
Nima Moghaddam 1 collaboration
John R Swiston 1 collaboration
Jason Weatherald 1 collaboration
Nathan Hambly 1 collaboration
T Semalulu 1 collaboration
L Rudski 1 collaboration
T Huynh 1 collaboration
M Wang 1 collaboration
M J Fritzler 1 collaboration
J Pope 1 collaboration
M Baron 1 collaboration
M Hudson 1 collaboration
Laura Scelsi 1 collaboration
Amresh Raina 1 collaboration
Hikmet Al-Hiti 1 collaboration
Sung-A Chang 1 collaboration
J Simon R Gibbs 1 collaboration
Gisela M B Meyer 1 collaboration
Jaquelina Ota-Arakaki 1 collaboration
Andrew J Peacock 1 collaboration
Tomás Pulido 1 collaboration
Carmine Dario Vizza 1 collaboration
Anton Vonk-Noordegraaf 1 collaboration
Karen Paraschin 1 collaboration
Hossein Ardeschir Ghofrani 1 collaboration
Jim White 1 collaboration
Jennifer E Fragale 1 collaboration
Morgan H James 1 collaboration
Jorge A Avila 1 collaboration
Andrea M Spaeth 1 collaboration
R Nisha Aurora 1 collaboration
Gary Aston-Jones 1 collaboration
Nathan Messas 1 collaboration
Roberto Badagliacca 1 collaboration
Carmine D Vizza 1 collaboration