Dagmar Heydeck

Affiliations

Institute of Biochemistry, Charite - University Medicine Berlin, Corporate member of Free University Berlin, Humboldt University Berlin and Berlin Institute of Health, Charitéplatz 1, D-10117 Berlin, Germany.

Publications (21)

Identification of the COMM-domain containing protein 1 as specific binding partner for the guanine-rich RNA sequence binding factor 1.

Biochimica et biophysica acta. General subjects

Avec: Bernhard Dumoulin , Christoph Ufer , Sabine Stehling , Dagmar Heydeck , Hartmut Kuhn , Sajad Sofi

Male guanine-rich RNA sequence binding factor 1 knockout mice (Grsf1

Cell & bioscience

Avec: Bernhard Dumoulin , Dagmar Heydeck , Desiree Jähn , Moritz Lassé , Sajad Sofi , Christoph Ufer , Hartmut Kuhn

The Reaction Specificity of Mammalian ALOX15 Orthologs is Changed During Late Primate Evolution and These Alterations Might Offer Evolutionary Advantages for Hominidae.

Frontiers in cell and developmental biology

Avec: Dagmar Heydeck , Florian Reisch , Marjann Schäfer , Kumar R Kakularam , Sophie A Roigas , Sabine Stehling , Gerhard P Püschel , Hartmut Kuhn

Bony Fish Arachidonic Acid 15-Lipoxygenases Exhibit Different Catalytic Properties than Their Mammalian Orthologs, Suggesting Functional Enzyme Evolution during Vertebrate Development.

International journal of molecular sciences

Avec: Sophie Roigas , Kumar R Kakularam , Michael Rothe , Dagmar Heydeck , Polamarasetty Aparoy , Hartmut Kuhn

Male Knock-in Mice Expressing an Arachidonic Acid Lipoxygenase 15B (Alox15B) with Humanized Reaction Specificity Are Prematurely Growth Arrested When Aging.

Biomedicines

Avec: Marjann Schäfer , Kumar R Kakularam , Florian Reisch , Michael Rothe , Sabine Stehling , Dagmar Heydeck , Gerhard P Püschel , Hartmut Kuhn

Humanization of the Reaction Specificity of Mouse Alox15b Inversely Modified the Susceptibility of Corresponding Knock-In Mice in Two Different Animal Inflammation Models.

International journal of molecular sciences

Avec: Marjann Schäfer , Florian Reisch , Dominika Labuz , Halina Machelska , Sabine Stehling , Gerhard P Püschel , Michael Rothe , Dagmar Heydeck , Hartmut Kuhn

Atopic Patients Show Increased Interleukin 4 Plasma Levels but the Degree of Elevation Is Not Sufficient to Upregulate Interleukin-4-Sensitive Genes.

Skin pharmacology and physiology

Avec: Eugenia Marbach-Breitrück , Andrea Kalledat , Dagmar Heydeck , Sabine Stehling , Joachim W Fluhr , Torsten Zuberbier , Hartmut Kuhn

Functional characterization of novel ALOX15 orthologs representing key steps in mammalian evolution supports the Evolutionary Hypothesis of reaction specificity.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Avec: Nikita Kozlov , Lia Humeniuk , Christoph Ufer , Igor Ivanov , Alexey Golovanov , Sabine Stehling , Dagmar Heydeck , Hartmut Kuhn

Knock-in mice expressing a humanized arachidonic acid 15-lipoxygenase (Alox15) carry a partly dysfunctional erythropoietic system.

Cellular & molecular biology letters

Avec: Florian Reisch , Dagmar Heydeck , Marjann Schäfer , Michael Rothe , Jiaxing Yang , Sabine Stehling , Gerhard P Püschel , Hartmut Kuhn

A role of Gln596 in fine-tuning mammalian ALOX15 specificity, protein stability and allosteric properties.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Avec: Alejandro Cruz , Almerinda Di Venere , Giampiero Mei , Alexander Zhuravlev , Alexey Golovanov , Sabine Stehling , Dagmar Heydeck , José M Lluch , Àngels González-Lafont , Hartmut Kuhn , Igor Ivanov

Mutations of Triad Determinants Changes the Substrate Alignment at the Catalytic Center of Human ALOX5.

ACS chemical biology

Avec: Igor Ivanov , Alexey B Golovanov , Cristián Ferretti , Miquel Canyelles-Niño , Dagmar Heydeck , Sabine Stehling , José M Lluch , Àngels González-Lafont , Hartmut Kühn

Knock-In Mice Expressing a 15-Lipoxygenating Alox5 Mutant Respond Differently to Experimental Inflammation Than Reported

Metabolites

Avec: Eugenia Marbach-Breitrück , Nadine Rohwer , Carmen Infante-Duarte , Silvina Romero-Suarez , Dominika Labuz , Halina Machelska , Laura Kutzner , Nils Helge Schebb , Michael Rothe , Pallu Reddanna , Karsten H Weylandt , Lothar H Wieler , Dagmar Heydeck , Hartmut Kuhn

Paralog- and ortholog-specificity of inhibitors of human and mouse lipoxygenase-isoforms.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: Kumar Reddy Kakularam , Felix Karst , Aparoy Polamarasetty , Igor Ivanov , Dagmar Heydeck , Hartmut Kuhn

Functional Characterization of Transgenic Mice Overexpressing Human 15-Lipoxygenase-1 (ALOX15) under the Control of the aP2 Promoter.

International journal of molecular sciences

Avec: Dagmar Heydeck , Christoph Ufer , Kumar R Kakularam , Michael Rothe , Thomas Liehr , Philippe Poulain , Hartmut Kuhn

Eicosanoid biosynthesizing enzymes in Prototheria.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Avec: Kumar R Kakularam , Eda Gündem , Sabine Stehling , Michael Rothe , Dagmar Heydeck , Hartmut Kuhn

The lipoxygenase pathway of Tupaia belangeri representing Scandentia. Genomic multiplicity and functional characterization of the ALOX15 orthologs in the tree shrew.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Avec: Marjann Schäfer , Yu Fan , Tianle Gu , Dagmar Heydeck , Sabine Stehling , Igor Ivanov , Yong-Gang Yao , Hartmut Kuhn

Functional characterization of a novel arachidonic acid 12S-lipoxygenase in the halotolerant bacterium Myxococcus fulvus exhibiting complex social living patterns.

MicrobiologyOpen

Avec: Kateryna Goloshchapova , Sabine Stehling , Dagmar Heydeck , Maximilian Blum , Hartmut Kuhn

Eicosanoid biosynthesis in marine mammals.

The FEBS journal

Avec: Florian Reisch , Kumar Reddy Kakularam , Sabine Stehling , Dagmar Heydeck , Hartmut Kuhn

Oxygenation of endocannabinoids by mammalian lipoxygenase isoforms.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Avec: Igor Ivanov , Kumar R Kakularam , Elena V Shmendel , Michael Rothe , Polamarasetty Aparoy , Dagmar Heydeck , Hartmut Kuhn

Functional Characterization of Novel Bony Fish Lipoxygenase Isoforms and Their Possible Involvement in Inflammation.

International journal of molecular sciences

Avec: Sophie Roigas , Dagmar Heydeck , Hartmut Kuhn

Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protected in the complete Freund's adjuvant-induced paw inflammation model.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]

Avec: Dagmar Heydeck , Kumar R Kakularam , Dominika Labuz , Halina Machelska , Nadine Rohwer , Karsten Weylandt , Hartmut Kuhn

Réseau de co-auteurs

Hartmut Kuhn 20 collaborations

Sabine Stehling 13 collaborations

Michael Rothe 8 collaborations

Kumar R Kakularam 7 collaborations

Igor Ivanov 6 collaborations

Florian Reisch 5 collaborations

Marjann Schäfer 5 collaborations

Christoph Ufer 4 collaborations

Gerhard P Püschel 4 collaborations

Dominika Labuz 3 collaborations

Halina Machelska 3 collaborations

Bernhard Dumoulin 2 collaborations

Sajad Sofi 2 collaborations

Sophie Roigas 2 collaborations

Polamarasetty Aparoy 2 collaborations

Eugenia Marbach-Breitrück 2 collaborations

Alexey Golovanov 2 collaborations

José M Lluch 2 collaborations

Àngels González-Lafont 2 collaborations

Nadine Rohwer 2 collaborations

Kumar Reddy Kakularam 2 collaborations

Desiree Jähn 1 collaboration

Moritz Lassé 1 collaboration

Sophie A Roigas 1 collaboration

Andrea Kalledat 1 collaboration

Joachim W Fluhr 1 collaboration

Torsten Zuberbier 1 collaboration

Nikita Kozlov 1 collaboration

Lia Humeniuk 1 collaboration

Jiaxing Yang 1 collaboration

Alejandro Cruz 1 collaboration

Almerinda Di Venere 1 collaboration

Giampiero Mei 1 collaboration

Alexander Zhuravlev 1 collaboration

Alexey B Golovanov 1 collaboration

Cristián Ferretti 1 collaboration

Miquel Canyelles-Niño 1 collaboration

Hartmut Kühn 1 collaboration

Carmen Infante-Duarte 1 collaboration

Silvina Romero-Suarez 1 collaboration

Laura Kutzner 1 collaboration

Nils Helge Schebb 1 collaboration

Pallu Reddanna 1 collaboration

Karsten H Weylandt 1 collaboration

Lothar H Wieler 1 collaboration

Felix Karst 1 collaboration

Aparoy Polamarasetty 1 collaboration

Thomas Liehr 1 collaboration

Philippe Poulain 1 collaboration

Eda Gündem 1 collaboration

Yu Fan 1 collaboration

Tianle Gu 1 collaboration

Yong-Gang Yao 1 collaboration

Kateryna Goloshchapova 1 collaboration

Maximilian Blum 1 collaboration

Elena V Shmendel 1 collaboration

Karsten Weylandt 1 collaboration