Daniel T Utzschneider

Affiliations

Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia. daniel.utzschneider@unimelb.edu.au.

ORCID: http://orcid.org/0000-0003-2205-9057

Publications (16)

Early precursor T cells establish and propagate T cell exhaustion in chronic infection.

Nature immunology

Avec: Daniel T Utzschneider , Sarah S Gabriel , David Chisanga , Renee Gloury , Patrick M Gubser , Ajithkumar Vasanthakumar , Wei Shi , Axel Kallies

Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches.

Immunity

Avec: Sabrina Dähling , Ana Maria Mansilla , Konrad Knöpper , Anika Grafen , Daniel T Utzschneider , Milas Ugur , Paul G Whitney , Annabell Bachem , Panagiota Arampatzi , Fabian Imdahl , Tsuneyasu Kaisho , Dietmar Zehn , Frederick Klauschen , Natalio Garbi , Axel Kallies , Antoine-Emmanuel Saliba , Georg Gasteiger , Sammy Bedoui , Wolfgang Kastenmüller

IRF2 integrates inflammatory signals to balance T cell exhaustion.

Immunity

Avec: Amania A Sheikh , Daniel T Utzschneider

Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection.

Immunity

Avec: Lucy Cooper , Hui Xu , Jack Polmear , Liam Kealy , Christopher Szeto , Ee Shan Pang , Mansi Gupta , Alana Kirn , Justin J Taylor , Katherine J L Jackson , Benjamin J Broomfield , Angela Nguyen , Catarina Gago da Graça , Nicole La Gruta , Daniel T Utzschneider , Joanna R Groom , Luciano Martelotto , Ian A Parish , Meredith O'Keeffe , Christopher D Scharer , Stephanie Gras , Kim L Good-Jacobson

Mouse guanylate-binding proteins of the chromosome 3 cluster do not mediate antiviral activity in vitro or in mouse models of infection.

Communications biology

Avec: Melkamu B Tessema , Shouya Feng , Daniel Enosi Tuipulotu , Rubaiyea Farrukee , Chinh Ngo , Catarina Gago da Graça , Masahiro Yamomoto , Daniel T Utzschneider , Andrew G Brooks , Sarah L Londrigan , Si Ming Man , Patrick C Reading

Human effector T cells express TOX-Not so "TOX"ic after all.

Science immunology

Avec: Daniel T Utzschneider , Axel Kallies

MiR-23~27~24-mediated control of humoral immunity reveals a TOX-driven regulatory circuit in follicular helper T cell differentiation.

Science advances

Avec: Cheng-Jang Wu , Sunglim Cho , Hsi-Yuan Huang , Chun-Hao Lu , Jasmin Russ , Leilani O Cruz , Flavia Franco da Cunha , Mei-Chi Chen , Ling-Li Lin , Lindsey M Warner , Hsin-Kai Liao , Daniel T Utzschneider , Sara Quon , Jacqueline Berner , Niels Olsen Saraiva Camara , Dietmar Zehn , Juan Carlos Izpisua Belmonte , Li-Chen Chen , Shiang-Fu Huang , Ming-Ling Kuo , Li-Fan Lu

TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection.

Nature

Avec: Francesca Alfei , Kristiyan Kanev , Maike Hofmann , Ming Wu , Hazem E Ghoneim , Patrick Roelli , Daniel T Utzschneider , Madlaina von Hoesslin , Jolie G Cullen , Yiping Fan , Vasyl Eisenberg , Dirk Wohlleber , Katja Steiger , Doron Merkler , Mauro Delorenzi , Percy A Knolle , Cyrille J Cohen , Robert Thimme , Benjamin Youngblood , Dietmar Zehn

The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1

Immunity

Avec: Anna-Friederike Marx , Sandra M Kallert , Tobias M Brunner , José A Villegas , Florian Geier , Jonas Fixemer , Tiago Abreu-Mota , Peter Reuther , Weldy V Bonilla , Jelizaveta Fadejeva , Mario Kreutzfeldt , Ingrid Wagner , Patricia Aparicio-Domingo , Leo Scarpellino , Mélanie Charmoy , Daniel T Utzschneider , Claudia Hagedorn , Min Lu , Karen Cornille , Karsten Stauffer , Florian Kreppel , Doron Merkler , Dietmar Zehn , Werner Held , Sanjiv A Luther , Max Löhning , Daniel D Pinschewer

Venetoclax Dose Escalation Rapidly Activates a BAFF/BCL-2 Survival Axis in Chronic Lymphocytic Leukemia.

Blood

Avec: Meng-Xiao Luo , Tania Tan , Marie Trussart , Annika Poch , Minh-Hanh Thi Nguyen , Terence P Speed , Damien G Hicks , Esther Bandala-Sanchez , Hongke Peng , Stephane Chappaz , Charlotte Slade , Daniel T Utzschneider , Rachel M Koldej , David Ritchie , Andreas Strasser , Rachel Thijssen , Matthew E Ritchie , Constantine Si Lun Tam , Geoffrey J Lindeman , David Ching Siang Huang , Thomas E Lew , Mary Ann Anderson , Andrew W Roberts , Charis E Teh , Daniel H D Gray

Antigen-driven EGR2 expression is required for exhausted CD8

Nature communications

Avec: Mayura V Wagle , Stephin J Vervoort , Madison J Kelly , Willem Van Der Byl , Timothy J Peters , Ben P Martin , Luciano G Martelotto , Simone Nüssing , Kelly M Ramsbottom , James R Torpy , Deborah Knight , Sinead Reading , Kevin Thia , Lisa A Miosge , Debbie R Howard , Renee Gloury , Sarah S Gabriel , Daniel T Utzschneider , Jane Oliaro , Jonathan D Powell , Fabio Luciani , Joseph A Trapani , Ricky W Johnstone , Axel Kallies , Christopher C Goodnow , Ian A Parish

MYB orchestrates T cell exhaustion and response to checkpoint inhibition.

Nature

Avec: Carlson Tsui , Lorenz Kretschmer , Svenja Rapelius , Sarah S Gabriel , David Chisanga , Konrad Knöpper , Daniel T Utzschneider , Simone Nüssing , Yang Liao , Teisha Mason , Santiago Valle Torres , Stephen A Wilcox , Krystian Kanev , Sebastian Jarosch , Justin Leube , Stephen L Nutt , Dietmar Zehn , Ian A Parish , Wolfgang Kastenmüller , Wei Shi , Veit R Buchholz , Axel Kallies

TGF-β specifies T

Science immunology

Avec: Yinshui Chang , Luisa Bach , Marko Hasiuk , Lifen Wen , Tarek Elmzzahi , Carlson Tsui , Nicolás Gutiérrez-Melo , Teresa Steffen , Daniel T Utzschneider , Timsse Raj , Paul Jonas Jost , Sylvia Heink , Jingyuan Cheng , Oliver T Burton , Julia Zeiträg , Dominik Alterauge , Frank Dahlström , Jennifer-Christin Becker , Melanie Kastl , Konstantinos Symeonidis , Martina van Uelft , Matthias Becker , Sarah Reschke , Stefan Krebs , Helmut Blum , Zeinab Abdullah , Katrin Paeschke , Caspar Ohnmacht , Christian Neumann , Adrian Liston , Felix Meissner , Thomas Korn , Jan Hasenauer , Vigo Heissmeyer , Marc Beyer , Axel Kallies , Lukas T Jeker , Dirk Baumjohann

Precursor exhausted T cells: key to successful immunotherapy?

Nature reviews. Immunology

Avec: Axel Kallies , Dietmar Zehn , Daniel T Utzschneider

Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection.

Immunity

Avec: Sarah S Gabriel , Carlson Tsui , David Chisanga , Flora Weber , Manuela Llano-León , Patrick M Gubser , Laurent Bartholin , Fernando Souza-Fonseca-Guimaraes , Nicholas D Huntington , Wei Shi , Daniel T Utzschneider , Axel Kallies

Aerobic glycolysis but not GLS1-dependent glutamine metabolism is critical for anti-tumor immunity and response to checkpoint inhibition.

Cell reports

Avec: Patrick M Gubser , Sharanya Wijesinghe , Leonie Heyden , Sarah S Gabriel , David P de Souza , Christoph Hess , Malcolm M McConville , Daniel T Utzschneider , Axel Kallies

Réseau de co-auteurs

Axel Kallies 9 collaborations

Dietmar Zehn 6 collaborations

Sarah S Gabriel 5 collaborations

David Chisanga 3 collaborations

Patrick M Gubser 3 collaborations

Wei Shi 3 collaborations

Ian A Parish 3 collaborations

Carlson Tsui 3 collaborations

Renee Gloury 2 collaborations

Konrad Knöpper 2 collaborations

Wolfgang Kastenmüller 2 collaborations

Catarina Gago da Graça 2 collaborations

Doron Merkler 2 collaborations

Simone Nüssing 2 collaborations

Ajithkumar Vasanthakumar 1 collaboration

Sabrina Dähling 1 collaboration

Ana Maria Mansilla 1 collaboration

Anika Grafen 1 collaboration

Milas Ugur 1 collaboration

Paul G Whitney 1 collaboration

Annabell Bachem 1 collaboration

Panagiota Arampatzi 1 collaboration

Fabian Imdahl 1 collaboration

Tsuneyasu Kaisho 1 collaboration

Frederick Klauschen 1 collaboration

Natalio Garbi 1 collaboration

Antoine-Emmanuel Saliba 1 collaboration

Georg Gasteiger 1 collaboration

Sammy Bedoui 1 collaboration

Amania A Sheikh 1 collaboration

Lucy Cooper 1 collaboration

Hui Xu 1 collaboration

Jack Polmear 1 collaboration

Liam Kealy 1 collaboration

Christopher Szeto 1 collaboration

Ee Shan Pang 1 collaboration

Mansi Gupta 1 collaboration

Alana Kirn 1 collaboration

Justin J Taylor 1 collaboration

Katherine J L Jackson 1 collaboration

Benjamin J Broomfield 1 collaboration

Angela Nguyen 1 collaboration

Nicole La Gruta 1 collaboration

Joanna R Groom 1 collaboration

Luciano Martelotto 1 collaboration

Meredith O'Keeffe 1 collaboration

Christopher D Scharer 1 collaboration

Stephanie Gras 1 collaboration

Kim L Good-Jacobson 1 collaboration

Melkamu B Tessema 1 collaboration

Shouya Feng 1 collaboration

Daniel Enosi Tuipulotu 1 collaboration

Rubaiyea Farrukee 1 collaboration

Chinh Ngo 1 collaboration

Masahiro Yamomoto 1 collaboration

Andrew G Brooks 1 collaboration

Sarah L Londrigan 1 collaboration

Si Ming Man 1 collaboration

Patrick C Reading 1 collaboration

Cheng-Jang Wu 1 collaboration

Sunglim Cho 1 collaboration

Hsi-Yuan Huang 1 collaboration

Chun-Hao Lu 1 collaboration

Jasmin Russ 1 collaboration

Leilani O Cruz 1 collaboration

Flavia Franco da Cunha 1 collaboration

Mei-Chi Chen 1 collaboration

Ling-Li Lin 1 collaboration

Lindsey M Warner 1 collaboration

Hsin-Kai Liao 1 collaboration

Sara Quon 1 collaboration

Jacqueline Berner 1 collaboration

Niels Olsen Saraiva Camara 1 collaboration

Juan Carlos Izpisua Belmonte 1 collaboration

Li-Chen Chen 1 collaboration

Shiang-Fu Huang 1 collaboration

Ming-Ling Kuo 1 collaboration

Li-Fan Lu 1 collaboration

Francesca Alfei 1 collaboration

Kristiyan Kanev 1 collaboration

Maike Hofmann 1 collaboration

Ming Wu 1 collaboration

Hazem E Ghoneim 1 collaboration

Patrick Roelli 1 collaboration

Madlaina von Hoesslin 1 collaboration

Jolie G Cullen 1 collaboration

Yiping Fan 1 collaboration

Vasyl Eisenberg 1 collaboration

Dirk Wohlleber 1 collaboration

Katja Steiger 1 collaboration

Mauro Delorenzi 1 collaboration

Percy A Knolle 1 collaboration

Cyrille J Cohen 1 collaboration

Robert Thimme 1 collaboration

Benjamin Youngblood 1 collaboration

Anna-Friederike Marx 1 collaboration

Sandra M Kallert 1 collaboration

Tobias M Brunner 1 collaboration

José A Villegas 1 collaboration

Florian Geier 1 collaboration

Jonas Fixemer 1 collaboration

Tiago Abreu-Mota 1 collaboration

Peter Reuther 1 collaboration

Weldy V Bonilla 1 collaboration

Jelizaveta Fadejeva 1 collaboration

Mario Kreutzfeldt 1 collaboration

Ingrid Wagner 1 collaboration

Patricia Aparicio-Domingo 1 collaboration

Leo Scarpellino 1 collaboration

Mélanie Charmoy 1 collaboration

Claudia Hagedorn 1 collaboration

Min Lu 1 collaboration

Karen Cornille 1 collaboration

Karsten Stauffer 1 collaboration

Florian Kreppel 1 collaboration

Werner Held 1 collaboration

Sanjiv A Luther 1 collaboration

Max Löhning 1 collaboration

Daniel D Pinschewer 1 collaboration

Meng-Xiao Luo 1 collaboration

Tania Tan 1 collaboration

Marie Trussart 1 collaboration

Annika Poch 1 collaboration

Minh-Hanh Thi Nguyen 1 collaboration

Terence P Speed 1 collaboration

Damien G Hicks 1 collaboration

Esther Bandala-Sanchez 1 collaboration

Hongke Peng 1 collaboration

Stephane Chappaz 1 collaboration

Charlotte Slade 1 collaboration

Rachel M Koldej 1 collaboration

David Ritchie 1 collaboration

Andreas Strasser 1 collaboration

Rachel Thijssen 1 collaboration

Matthew E Ritchie 1 collaboration

Constantine Si Lun Tam 1 collaboration

Geoffrey J Lindeman 1 collaboration

David Ching Siang Huang 1 collaboration

Thomas E Lew 1 collaboration

Mary Ann Anderson 1 collaboration

Andrew W Roberts 1 collaboration

Charis E Teh 1 collaboration

Daniel H D Gray 1 collaboration

Mayura V Wagle 1 collaboration

Stephin J Vervoort 1 collaboration

Madison J Kelly 1 collaboration

Willem Van Der Byl 1 collaboration

Timothy J Peters 1 collaboration

Ben P Martin 1 collaboration

Luciano G Martelotto 1 collaboration

Kelly M Ramsbottom 1 collaboration

James R Torpy 1 collaboration

Deborah Knight 1 collaboration

Sinead Reading 1 collaboration

Kevin Thia 1 collaboration

Lisa A Miosge 1 collaboration

Debbie R Howard 1 collaboration

Jane Oliaro 1 collaboration

Jonathan D Powell 1 collaboration

Fabio Luciani 1 collaboration

Joseph A Trapani 1 collaboration

Ricky W Johnstone 1 collaboration

Christopher C Goodnow 1 collaboration

Lorenz Kretschmer 1 collaboration

Svenja Rapelius 1 collaboration

Yang Liao 1 collaboration

Teisha Mason 1 collaboration

Santiago Valle Torres 1 collaboration

Stephen A Wilcox 1 collaboration

Krystian Kanev 1 collaboration

Sebastian Jarosch 1 collaboration

Justin Leube 1 collaboration

Stephen L Nutt 1 collaboration

Veit R Buchholz 1 collaboration

Yinshui Chang 1 collaboration

Luisa Bach 1 collaboration

Marko Hasiuk 1 collaboration

Lifen Wen 1 collaboration

Tarek Elmzzahi 1 collaboration

Nicolás Gutiérrez-Melo 1 collaboration

Teresa Steffen 1 collaboration

Timsse Raj 1 collaboration

Paul Jonas Jost 1 collaboration

Sylvia Heink 1 collaboration

Jingyuan Cheng 1 collaboration

Oliver T Burton 1 collaboration

Julia Zeiträg 1 collaboration

Dominik Alterauge 1 collaboration

Frank Dahlström 1 collaboration

Jennifer-Christin Becker 1 collaboration

Melanie Kastl 1 collaboration

Konstantinos Symeonidis 1 collaboration

Martina van Uelft 1 collaboration

Matthias Becker 1 collaboration

Sarah Reschke 1 collaboration

Stefan Krebs 1 collaboration

Helmut Blum 1 collaboration

Zeinab Abdullah 1 collaboration

Katrin Paeschke 1 collaboration

Caspar Ohnmacht 1 collaboration

Christian Neumann 1 collaboration

Adrian Liston 1 collaboration

Felix Meissner 1 collaboration

Thomas Korn 1 collaboration

Jan Hasenauer 1 collaboration

Vigo Heissmeyer 1 collaboration

Marc Beyer 1 collaboration

Lukas T Jeker 1 collaboration

Dirk Baumjohann 1 collaboration

Flora Weber 1 collaboration

Manuela Llano-León 1 collaboration

Laurent Bartholin 1 collaboration

Fernando Souza-Fonseca-Guimaraes 1 collaboration

Nicholas D Huntington 1 collaboration

Sharanya Wijesinghe 1 collaboration

Leonie Heyden 1 collaboration

David P de Souza 1 collaboration

Christoph Hess 1 collaboration

Malcolm M McConville 1 collaboration