Fernanda Laezza

Affiliations

Department of Pharmacology & Toxicology, The University of Texas Medical Branch, Galveston, TX, USA; Center for Addiction Research, The University of Texas Medical Branch, Galveston, TX, USA. Electronic address: felaezza@utmb.edu.

Publications (30)

JAK2 regulates Nav1.6 channel function via FGF14

Biochimica et biophysica acta. Molecular cell research

Avec: Paul A Wadsworth , Aditya K Singh , Nghi Nguyen , Nolan M Dvorak , Cynthia M Tapia , William K Russell , Clifford Stephan , Fernanda Laezza

Sex-Specific Proteomic Changes Induced by Genetic Deletion of Fibroblast Growth Factor 14 (FGF14), a Regulator of Neuronal Ion Channels.

Proteomes

Avec: Mark L Sowers , Jessica Di Re , Paul A Wadsworth , Alexander S Shavkunov , Cheryl Lichti , Kangling Zhang , Fernanda Laezza

Differential Modulation of the Voltage-Gated Na

Frontiers in molecular biosciences

Avec: Aditya K Singh , Nolan M Dvorak , Cynthia M Tapia , Angela Mosebarger , Syed R Ali , Zaniqua Bullock , Haiying Chen , Jia Zhou , Fernanda Laezza

Fibroblast growth factor 13-mediated regulation of medium spiny neuron excitability and cocaine self-administration.

Frontiers in neuroscience

Avec: Nolan M Dvorak , Jessica Di Re , Tileena E S Vasquez , Mate Marosi , Poonam Shah , Yorkiris M Mármol Contreras , Matteo Bernabucci , Aditya K Singh , Jariatu Stallone , Thomas A Green , Fernanda Laezza

TNFR1 signaling converging on FGF14 controls neuronal hyperactivity and sickness behavior in experimental cerebral malaria.

Journal of neuroinflammation

Avec: Nolan M Dvorak , Nadia D Domingo , Cynthia M Tapia , Paul A Wadsworth , Mate Marosi , Yosef Avchalumov , Chanida Fongsaran , Leandra Koff , Jessica Di Re , Catherine M Sampson , Timothy J Baumgartner , Pingyuan Wang , Paula P Villarreal , Olivia D Solomon , Sonja J Stutz , Aditi , Jacob Porter , Komi Gbedande , Brendan Prideaux , Thomas A Green , Erin H Seeley , Parimal Samir , Kelley T Dineley , Gracie Vargas , Jia Zhou , Irma Cisneros , Robin Stephens , Fernanda Laezza

Bar press durations as a reliable and robust measure of frustration-related operant behavior: Sensitivity to incentive downshift and dose-response paradigms.

PloS one

Avec: Yorkiris Mármol Contreras , Tileena E S Vasquez , Poonam Shah , Kelsey Payne , Jessica Di Re , Fernanda Laezza , Thomas A Green

Broader phenotypic traits and widespread brain hypometabolism in spinocerebellar ataxia 27.

Journal of internal medicine

Avec: M Paucar , J Lundin , T Alshammari , Å Bergendal , M Lindefeldt , M Alshammari , G Solders , J Di Re , I Savitcheva , T Granberg , F Laezza , E Iwarsson , P Svenningsson

Identification of peptidomimetics as novel chemical probes modulating fibroblast growth factor 14 (FGF14) and voltage-gated sodium channel 1.6 (Nav1.6) protein-protein interactions.

Bioorganic & medicinal chemistry letters

Avec: Zhiqing Liu , Paul Wadsworth , Aditya K Singh , Haiying Chen , Pingyuan Wang , Oluwarotimi Folorunso , Pietro Scaduto , Syed R Ali , Fernanda Laezza , Jia Zhou

Design, Synthesis, and Pharmacological Evaluation of Analogues Derived from the PLEV Tetrapeptide as Protein-Protein Interaction Modulators of Voltage-Gated Sodium Channel 1.6.

Journal of medicinal chemistry

Avec: Pingyuan Wang , Paul A Wadsworth , Nolan M Dvorak , Aditya K Singh , Haiying Chen , Zhiqing Liu , Richard Zhou , Luis Marcelo F Holthauzen , Jia Zhou , Fernanda Laezza

Topographic transcriptomics of the nucleus accumbens shell: Identification and validation of fatty acid binding protein 5 as target for cocaine addiction.

Neuropharmacology

Avec: Elizabeth J Crofton , Miroslav N Nenov , Yafang Zhang , Cynthia M Tapia , Joseph Donnelly , Shyny Koshy , Fernanda Laezza , Thomas A Green

A Learning Based Framework for Disease Prediction from Images of Human-Derived Pluripotent Stem Cells of Schizophrenia Patients.

Neuroinformatics

Avec: Nickolas Fularczyk , Jessica Di Re , Laura Stertz , Consuelo Walss-Bass , Fernanda Laezza , Demetrio Labate

Voltage-Gated Na

Life (Basel, Switzerland)

Avec: Timothy J Baumgartner , Zahra Haghighijoo , Nana A Goode , Nolan M Dvorak , Parsa Arman , Fernanda Laezza

Crosstalk among WEE1 Kinase, AKT, and GSK3 in Nav1.2 Channelosome Regulation.

International journal of molecular sciences

Avec: Aditya K Singh , Jully Singh , Nana A Goode , Fernanda Laezza

Imaging of the Axon Initial Segment.

Current protocols in neuroscience

Avec: Jessica Di Re , Cihan Kayasandik , Gonzalo Botello-Lins , Demetrio Labate , Fernanda Laezza

Assessing the role of toll-like receptor in isolated, standard and enriched housing conditions.

PloS one

Avec: Tahani K Alshammari , Hajar Alghamdi , Thomas A Green , Abdurahman Niazy , Lama Alkahdar , Nouf Alrasheed , Khalid Alhosaini , Mohammed Alswayyed , Ramesh Elango , Fernanda Laezza , Musaad A Alshammari , Hazar Yacoub

GSK3β Modulates Timing-Dependent Long-Term Depression Through Direct Phosphorylation of Kv4.2 Channels.

Cerebral cortex (New York, N.Y. : 1991)

Avec: Giuseppe Aceto , Agnese Re , Andrea Mattera , Lucia Leone , Claudia Colussi , Marco Rinaudo , Federico Scala , Katia Gironi , Saviana Antonella Barbati , Salvatore Fusco , Thomas Green , Fernanda Laezza , Marcello D'Ascenzo , Claudio Grassi

Pharmacological Inhibition of Wee1 Kinase Selectively Modulates the Voltage-Gated Na

Cells

Avec: Nolan M Dvorak , Cynthia M Tapia , Timothy J Baumgartner , Jully Singh , Fernanda Laezza , Aditya K Singh

Bioluminescence Methodology for Ion Channel Studies.

Methods in molecular biology (Clifton, N.J.)

Avec: Paul A Wadsworth , Aditya K Singh , Nghi Nguyen , Clifford Stephan , Fernanda Laezza

Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from schizophrenia patients.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Avec: Laura Stertz , Jessica Di Re , Guangsheng Pei , Gabriel R Fries , Emily Mendez , Shenglan Li , Laura Smith-Callahan , Henriette Raventos , Jerricho Tipo , Rohan Cherukuru , Zhongming Zhao , Ying Liu , Peilin Jia , Fernanda Laezza , Consuelo Walss-Bass

Emerging roles of Fgf14 in behavioral control.

Behavioural brain research

Avec: Eriola Hoxha , Andrea Marcinnò , Francesca Montarolo , Linda Masante , Ilaria Balbo , Francesco Ravera , Fernanda Laezza , Filippo Tempia

High-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na

Scientific reports

Avec: Paul A Wadsworth , Oluwarotimi Folorunso , Nghi Nguyen , Aditya K Singh , Daniela D'Amico , Reid T Powell , David Brunell , John Allen , Clifford Stephan , Fernanda Laezza

Bidirectional Modulation of the Voltage-Gated Sodium (Nav1.6) Channel by Rationally Designed Peptidomimetics.

Molecules (Basel, Switzerland)

Avec: Nolan M Dvorak , Paul A Wadsworth , Pingyuan Wang , Haiying Chen , Jia Zhou , Fernanda Laezza

Chronic mild stress alters synaptic plasticity in the nucleus accumbens through GSK3β-dependent modulation of Kv4.2 channels.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Giuseppe Aceto , Claudia Colussi , Lucia Leone , Salvatore Fusco , Marco Rinaudo , Federico Scala , Thomas A Green , Fernanda Laezza , Marcello D'Ascenzo , Claudio Grassi

Pharmacologically Targeting the Fibroblast Growth Factor 14 Interaction Site on the Voltage-Gated Na

International journal of molecular sciences

Avec: Nolan M Dvorak , Cynthia M Tapia , Aditya K Singh , Timothy J Baumgartner , Pingyuan Wang , Haiying Chen , Paul A Wadsworth , Jia Zhou , Fernanda Laezza

Inhibition of the Akt/PKB Kinase Increases Na

International journal of molecular sciences

Avec: Mate Marosi , Miroslav N Nenov , Jessica Di Re , Nolan M Dvorak , Musaad Alshammari , Fernanda Laezza

Glycogen Synthase Kinase 3: Ion Channels, Plasticity, and Diseases.

International journal of molecular sciences

Avec: Mate Marosi , Parsa Arman , Giuseppe Aceto , Marcello D'Ascenzo , Fernanda Laezza

Effects of Deltamethrin Acute Exposure on Nav1.6 Channels and Medium Spiny Neurons of the Nucleus Accumbens.

Toxicology

Avec: Cynthia M Tapia , Oluwarotimi Folorunso , Aditya K Singh , Kathleen McDonough , Fernanda Laezza

Mapping of the FGF14:Nav1.6 complex interface reveals FLPK as a functionally active peptide modulating excitability.

Physiological reports

Avec: Aditya K Singh , Paul A Wadsworth , Cynthia M Tapia , Giuseppe Aceto , Syed R Ali , Haiying Chen , Marcello D'Ascenzo , Jia Zhou , Fernanda Laezza

Development of Allosteric Modulators of Voltage-Gated Na

Current topics in medicinal chemistry

Avec: Nolan M Dvorak , Paul A Wadsworth , Pingyuan Wang , Jia Zhou , Fernanda Laezza

Inhibition of AKT Signaling Alters βIV Spectrin Distribution at the AIS and Increases Neuronal Excitability.

Frontiers in molecular neuroscience

Avec: Jessica Di Re , Wei-Chun J Hsu , Cihan B Kayasandik , Nickolas Fularczyk , T F James , Miroslav N Nenov , Pooran Negi , Mate Marosi , Federico Scala , Saurabh Prasad , Demetrio Labate , Fernanda Laezza

Réseau de co-auteurs

Aditya K Singh 12 collaborations

Nolan M Dvorak 11 collaborations

Paul A Wadsworth 10 collaborations

Jessica Di Re 9 collaborations

Cynthia M Tapia 8 collaborations

Jia Zhou 8 collaborations

Haiying Chen 6 collaborations

Thomas A Green 6 collaborations

Pingyuan Wang 6 collaborations

Mate Marosi 5 collaborations

Timothy J Baumgartner 4 collaborations

Giuseppe Aceto 4 collaborations

Marcello D'Ascenzo 4 collaborations

Nghi Nguyen 3 collaborations

Clifford Stephan 3 collaborations

Syed R Ali 3 collaborations

Oluwarotimi Folorunso 3 collaborations

Miroslav N Nenov 3 collaborations

Demetrio Labate 3 collaborations

Federico Scala 3 collaborations

Tileena E S Vasquez 2 collaborations

Poonam Shah 2 collaborations

Zhiqing Liu 2 collaborations

Nickolas Fularczyk 2 collaborations

Laura Stertz 2 collaborations

Consuelo Walss-Bass 2 collaborations

Nana A Goode 2 collaborations

Parsa Arman 2 collaborations

Jully Singh 2 collaborations

Lucia Leone 2 collaborations

Claudia Colussi 2 collaborations

Marco Rinaudo 2 collaborations

Salvatore Fusco 2 collaborations

Claudio Grassi 2 collaborations

William K Russell 1 collaboration

Mark L Sowers 1 collaboration

Alexander S Shavkunov 1 collaboration

Cheryl Lichti 1 collaboration

Kangling Zhang 1 collaboration

Angela Mosebarger 1 collaboration

Zaniqua Bullock 1 collaboration

Yorkiris M Mármol Contreras 1 collaboration

Matteo Bernabucci 1 collaboration

Jariatu Stallone 1 collaboration

Nadia D Domingo 1 collaboration

Yosef Avchalumov 1 collaboration

Chanida Fongsaran 1 collaboration

Leandra Koff 1 collaboration

Catherine M Sampson 1 collaboration

Paula P Villarreal 1 collaboration

Olivia D Solomon 1 collaboration

Sonja J Stutz 1 collaboration

None Aditi 1 collaboration

Jacob Porter 1 collaboration

Komi Gbedande 1 collaboration

Brendan Prideaux 1 collaboration

Erin H Seeley 1 collaboration

Parimal Samir 1 collaboration

Kelley T Dineley 1 collaboration

Gracie Vargas 1 collaboration

Irma Cisneros 1 collaboration

Robin Stephens 1 collaboration

Yorkiris Mármol Contreras 1 collaboration

Kelsey Payne 1 collaboration

M Paucar 1 collaboration

J Lundin 1 collaboration

T Alshammari 1 collaboration

Å Bergendal 1 collaboration

M Lindefeldt 1 collaboration

M Alshammari 1 collaboration

G Solders 1 collaboration

J Di Re 1 collaboration

I Savitcheva 1 collaboration

T Granberg 1 collaboration

F Laezza 1 collaboration

E Iwarsson 1 collaboration

P Svenningsson 1 collaboration

Paul Wadsworth 1 collaboration

Pietro Scaduto 1 collaboration

Richard Zhou 1 collaboration

Luis Marcelo F Holthauzen 1 collaboration

Elizabeth J Crofton 1 collaboration

Yafang Zhang 1 collaboration

Joseph Donnelly 1 collaboration

Shyny Koshy 1 collaboration

Zahra Haghighijoo 1 collaboration

Cihan Kayasandik 1 collaboration

Gonzalo Botello-Lins 1 collaboration

Tahani K Alshammari 1 collaboration

Hajar Alghamdi 1 collaboration

Abdurahman Niazy 1 collaboration

Lama Alkahdar 1 collaboration

Nouf Alrasheed 1 collaboration

Khalid Alhosaini 1 collaboration

Mohammed Alswayyed 1 collaboration

Ramesh Elango 1 collaboration

Musaad A Alshammari 1 collaboration

Hazar Yacoub 1 collaboration

Agnese Re 1 collaboration

Andrea Mattera 1 collaboration

Katia Gironi 1 collaboration

Saviana Antonella Barbati 1 collaboration

Thomas Green 1 collaboration

Guangsheng Pei 1 collaboration

Gabriel R Fries 1 collaboration

Emily Mendez 1 collaboration

Shenglan Li 1 collaboration

Laura Smith-Callahan 1 collaboration

Henriette Raventos 1 collaboration

Jerricho Tipo 1 collaboration

Rohan Cherukuru 1 collaboration

Zhongming Zhao 1 collaboration

Ying Liu 1 collaboration

Peilin Jia 1 collaboration

Eriola Hoxha 1 collaboration

Andrea Marcinnò 1 collaboration

Francesca Montarolo 1 collaboration

Linda Masante 1 collaboration

Ilaria Balbo 1 collaboration

Francesco Ravera 1 collaboration

Filippo Tempia 1 collaboration

Daniela D'Amico 1 collaboration

Reid T Powell 1 collaboration

David Brunell 1 collaboration

John Allen 1 collaboration

Musaad Alshammari 1 collaboration

Kathleen McDonough 1 collaboration

Wei-Chun J Hsu 1 collaboration

Cihan B Kayasandik 1 collaboration

T F James 1 collaboration

Pooran Negi 1 collaboration

Saurabh Prasad 1 collaboration