Giulia Guarguaglini

Affiliations

Institute of Molecular Biology and Pathology, National Research Council of Italy, c/o Department of Biology and Biotechnology, Sapienza University of Rome, Via degli Apuli 4, 00185 Rome, Italy. Electronic address: giulia.guarguaglini@uniroma1.it.

Publications (17)

The Aurora-A/TPX2 Axis Directs Spindle Orientation in Adherent Human Cells by Regulating NuMA and Microtubule Stability.

Current biology : CB

Avec: Federica Polverino , Francesco D Naso , Italia A Asteriti , Valentina Palmerini , Divya Singh , Davide Valente , Alexander W Bird , Alessandro Rosa , Marina Mapelli , Giulia Guarguaglini

Nuclear localisation of Aurora-A: its regulation and significance for Aurora-A functions in cancer.

Oncogene

Avec: Francesco Davide Naso , Dalila Boi , Camilla Ascanelli , Georgiana Pamfil , Catherine Lindon , Alessandro Paiardini , Giulia Guarguaglini

Revisiting the "satisfaction of spatial restraints" approach of MODELLER for protein homology modeling.

PLoS computational biology

Avec: Giacomo Janson , Alessandro Grottesi , Marco Pietrosanto , Gabriele Ausiello , Giulia Guarguaglini , Alessandro Paiardini

AURKA destruction is decoupled from its activity at mitotic exit but is essential to suppress interphase activity.

Journal of cell science

Avec: Ahmed Abdelbaki , H Begum Akman , Marion Poteau , Rhys Grant , Olivier Gavet , Giulia Guarguaglini , Catherine Lindon

M2 Muscarinic Receptor Activation Impairs Mitotic Progression and Bipolar Mitotic Spindle Formation in Human Glioblastoma Cell Lines.

Cells

Avec: Maria Di Bari , Vanessa Tombolillo , Francesco Alessandrini , Claudia Guerriero , Mario Fiore , Italia Anna Asteriti , Emilia Castigli , Miriam Sciaccaluga , Giulia Guarguaglini , Francesca Degrassi , Ada Maria Tata

ALFI: Cell cycle phenotype annotations of label-free time-lapse imaging data from cultured human cells.

Scientific data

Avec: Laura Antonelli , Federica Polverino , Alexandra Albu , Aroj Hada , Italia A Asteriti , Francesca Degrassi , Giulia Guarguaglini , Lucia Maddalena , Mario R Guarracino

AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation.

Life science alliance

Avec: Italia Anna Asteriti , Federica Polverino , Venturina Stagni , Valentina Sterbini , Camilla Ascanelli , Francesco Davide Naso , Anna Mastrangelo , Alessandro Rosa , Alessandro Paiardini , Catherine Lindon , Giulia Guarguaglini

When Just One Phosphate Is One Too Many: The Multifaceted Interplay between Myc and Kinases.

International journal of molecular sciences

Avec: Dalila Boi , Elisabetta Rubini , Sara Breccia , Giulia Guarguaglini , Alessandro Paiardini

M2 muscarinic receptors negatively modulate cell migration in human glioblastoma cells.

Neurochemistry international

Avec: Claudia Guerriero , Rachele Fanfarillo , Patrizia Mancini , Valentina Sterbini , Giulia Guarguaglini , Luigi Sforna , Antonio Michelucci , Luigi Catacuzzeno , Ada Maria Tata

X-ray irradiated cultures of mouse cortical neural stem/progenitor cells recover cell viability and proliferation with dose-dependent kinetics.

Scientific reports

Avec: Valerio Licursi , Silvia Anzellotti , Jessica Favaro , Serena Sineri , Nicoletta Carucci , Enrico Cundari , Mario Fiore , Giulia Guarguaglini , Simone Pippa , Paola S Nisi , Fiammetta Vernì , Stefano Biagioni , Emanuele Cacci , Roberto Amendola , Giuseppe Lupo , Rodolfo Negri

Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit.

Cells

Avec: Francesco D Naso , Valentina Sterbini , Elena Crecca , Italia A Asteriti , Alessandra D Russo , Maria Giubettini , Enrico Cundari , Catherine Lindon , Alessandro Rosa , Giulia Guarguaglini

PHA-680626 Is an Effective Inhibitor of the Interaction between Aurora-A and N-Myc.

International journal of molecular sciences

Avec: Dalila Boi , Fani Souvalidou , Davide Capelli , Federica Polverino , Grazia Marini , Roberta Montanari , Giorgio Pochetti , Angela Tramonti , Roberto Contestabile , Daniela Trisciuoglio , Patrizia Carpinelli , Camilla Ascanelli , Catherine Lindon , Alessandro De Leo , Michele Saviano , Roberto Di Santo , Roberta Costi , Giulia Guarguaglini , Alessandro Paiardini

Phosphorylation, Mg-ADP, and Inhibitors Differentially Shape the Conformational Dynamics of the A-Loop of Aurora-A.

Biomolecules

Avec: Zahra Musavizadeh , Alessandro Grottesi , Giulia Guarguaglini , Alessandro Paiardini

AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway.

Biochimica et biophysica acta. Molecular basis of disease

Avec: Francesco Davide Naso , Federica Polverino , Danilo Cilluffo , Linda Latini , Venturina Stagni , Italia Anna Asteriti , Alessandro Rosa , Silvia Soddu , Giulia Guarguaglini

Revisiting degron motifs in human AURKA required for its targeting by APC/C

Life science alliance

Avec: Ahmed Abdelbaki , Camilla Ascanelli , Cynthia N Okoye , H Begum Akman , Giacomo Janson , Mingwei Min , Chiara Marcozzi , Anja Hagting , Rhys Grant , Maria De Luca , Italia Anna Asteriti , Giulia Guarguaglini , Alessandro Paiardini , Catherine Lindon

AMBRA1 phosphorylation by CDK1 and PLK1 regulates mitotic spindle orientation.

Cellular and molecular life sciences : CMLS

Avec: Fiorella Faienza , Federica Polverino , Girish Rajendraprasad , Giacomo Milletti , Zehan Hu , Barbara Colella , Deborah Gargano , Flavie Strappazzon , Salvatore Rizza , Mette Vixø Vistesen , Yonglun Luo , Manuela Antonioli , Valentina Cianfanelli , Caterina Ferraina , Gian Maria Fimia , Giuseppe Filomeni , Daniela De Zio , Joern Dengjel , Marin Barisic , Giulia Guarguaglini , Sabrina Di Bartolomeo , Francesco Cecconi

Contribution of AurkA/TPX2 Overexpression to Chromosomal Imbalances and Cancer.

Cells

Avec: Federica Polverino , Anna Mastrangelo , Giulia Guarguaglini

Réseau de co-auteurs

Federica Polverino 7 collaborations

Alessandro Paiardini 7 collaborations

Catherine Lindon 6 collaborations

Alessandro Rosa 4 collaborations

Camilla Ascanelli 4 collaborations

Italia Anna Asteriti 4 collaborations

Italia A Asteriti 3 collaborations

Francesco Davide Naso 3 collaborations

Dalila Boi 3 collaborations

Valentina Sterbini 3 collaborations

Francesco D Naso 2 collaborations

Giacomo Janson 2 collaborations

Alessandro Grottesi 2 collaborations

Ahmed Abdelbaki 2 collaborations

H Begum Akman 2 collaborations

Rhys Grant 2 collaborations

Claudia Guerriero 2 collaborations

Mario Fiore 2 collaborations

Francesca Degrassi 2 collaborations

Ada Maria Tata 2 collaborations

Venturina Stagni 2 collaborations

Anna Mastrangelo 2 collaborations

Enrico Cundari 2 collaborations

Valentina Palmerini 1 collaboration

Divya Singh 1 collaboration

Davide Valente 1 collaboration

Alexander W Bird 1 collaboration

Marina Mapelli 1 collaboration

Georgiana Pamfil 1 collaboration

Marco Pietrosanto 1 collaboration

Gabriele Ausiello 1 collaboration

Marion Poteau 1 collaboration

Olivier Gavet 1 collaboration

Maria Di Bari 1 collaboration

Vanessa Tombolillo 1 collaboration

Francesco Alessandrini 1 collaboration

Emilia Castigli 1 collaboration

Miriam Sciaccaluga 1 collaboration

Laura Antonelli 1 collaboration

Alexandra Albu 1 collaboration

Aroj Hada 1 collaboration

Lucia Maddalena 1 collaboration

Mario R Guarracino 1 collaboration

Elisabetta Rubini 1 collaboration

Sara Breccia 1 collaboration

Rachele Fanfarillo 1 collaboration

Patrizia Mancini 1 collaboration

Luigi Sforna 1 collaboration

Antonio Michelucci 1 collaboration

Luigi Catacuzzeno 1 collaboration

Valerio Licursi 1 collaboration

Silvia Anzellotti 1 collaboration

Jessica Favaro 1 collaboration

Serena Sineri 1 collaboration

Nicoletta Carucci 1 collaboration

Simone Pippa 1 collaboration

Paola S Nisi 1 collaboration

Fiammetta Vernì 1 collaboration

Stefano Biagioni 1 collaboration

Emanuele Cacci 1 collaboration

Roberto Amendola 1 collaboration

Giuseppe Lupo 1 collaboration

Rodolfo Negri 1 collaboration

Elena Crecca 1 collaboration

Alessandra D Russo 1 collaboration

Maria Giubettini 1 collaboration

Fani Souvalidou 1 collaboration

Davide Capelli 1 collaboration

Grazia Marini 1 collaboration

Roberta Montanari 1 collaboration

Giorgio Pochetti 1 collaboration

Angela Tramonti 1 collaboration

Roberto Contestabile 1 collaboration

Daniela Trisciuoglio 1 collaboration

Patrizia Carpinelli 1 collaboration

Alessandro De Leo 1 collaboration

Michele Saviano 1 collaboration

Roberto Di Santo 1 collaboration

Roberta Costi 1 collaboration

Zahra Musavizadeh 1 collaboration

Danilo Cilluffo 1 collaboration

Linda Latini 1 collaboration

Silvia Soddu 1 collaboration

Cynthia N Okoye 1 collaboration

Mingwei Min 1 collaboration

Chiara Marcozzi 1 collaboration

Anja Hagting 1 collaboration

Maria De Luca 1 collaboration

Fiorella Faienza 1 collaboration

Girish Rajendraprasad 1 collaboration

Giacomo Milletti 1 collaboration

Zehan Hu 1 collaboration

Barbara Colella 1 collaboration

Deborah Gargano 1 collaboration

Flavie Strappazzon 1 collaboration

Salvatore Rizza 1 collaboration

Mette Vixø Vistesen 1 collaboration

Yonglun Luo 1 collaboration

Manuela Antonioli 1 collaboration

Valentina Cianfanelli 1 collaboration

Caterina Ferraina 1 collaboration

Gian Maria Fimia 1 collaboration

Giuseppe Filomeni 1 collaboration

Daniela De Zio 1 collaboration

Joern Dengjel 1 collaboration

Marin Barisic 1 collaboration

Sabrina Di Bartolomeo 1 collaboration

Francesco Cecconi 1 collaboration