Harold Keer

Affiliations

Astex Pharmaceuticals Inc., Pleasanton, California.

Publications (14)

A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Amit M Oza , Ursula A Matulonis , Angeles Alvarez Secord , John Nemunaitis , Lynda D Roman , Sarah P Blagden , Susana Banerjee , William P McGuire , Sharad Ghamande , Michael J Birrer , Gini F Fleming , Merry Jennifer Markham , Hal W Hirte , Diane M Provencher , Bristi Basu , Rebecca Kristeleit , Deborah K Armstrong , Benjamin Schwartz , Patricia Braly , Geoff D Hall , Kenneth P Nephew , Simone Jueliger , Aram Oganesian , Sue Naim , Yong Hao , Harold Keer , Mohammad Azab , Daniela Matei

Correction: A novel epigenetic modulating agent sensitizes pancreatic cells to a chemotherapy agent.

PloS one

Avec: Manjusha Thakar , Yue Hu , Michael Morreale , Lane Lerner , Wan Ying Lin , Rupashree Sen , Yi Cai , Enusha Karunasena , Maya Thakar , Soren Saggi , Harold Keer , Nita Ahuja

Antagonism of inhibitors of apoptosis proteins reveals a novel, immune response-based therapeutic approach for T-cell lymphoma.

Blood advances

Avec: Nicola Ferrari , George Ward , Christina Gewinner , Matthew P Davis , Simone Jueliger , Harpreet Saini , Joanne Munck , Tomoko Smyth , Roberta Ferraldeschi , Harold Keer , John Lyons , Martin J Sims

Correction: Phase II Study Evaluating 2 Dosing Schedules of Oral Foretinib (GSK1363089), cMET/VEGFR2 Inhibitor, in Patients with Metastatic Gastric Cancer.

PloS one

Avec: Manish A Shah , Zev A Wainberg , Daniel V T Catenacci , Howard S Hochster , James Ford , Pamela Kunz , Fa-Chyi Lee , Howard Kallender , Fabiola Cecchi , Daniel C Rabe , Harold Keer , Anne-Marie Martin , Yuan Liu , Robert Gagnon , Peter Bonate , Li Liu , Tona Gilmer , Donald P Bottaro

Real-world study of the use of azacitidine in myelodysplasia in Australia.

EJHaem

Avec: Anoop Enjeti , Asma Ashraf , Vincent Caillet , Arif Alam , Jonathan Silar , Harold Keer , Francesco Castaldi , Taleisha Paine

Oral Azacitidine and Cedazuridine Approximate Parenteral Azacitidine Efficacy in Murine Model.

Targeted oncology

Avec: Haley E Ramsey , Aram Oganesian , Agnieszka E Gorska , Londa Fuller , Maria Arrate , Kelli Boyd , Harold Keer , Mohammad Azab , Michael R Savona

A Phase I Study of ASTX660, an Antagonist of Inhibitors of Apoptosis Proteins, in Adults with Advanced Cancers or Lymphoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Monica M Mita , Patricia M LoRusso , Kyriakos P Papadopoulos , Michael S Gordon , Alain C Mita , Roberta Ferraldeschi , Harold Keer , Aram Oganesian , Xiang Yao Su , Simone Jueliger , Anthony W Tolcher

Correction: Phase II Study Evaluating 2 Dosing Schedules of Oral Foretinib (GSK1363089), cMET/VEGFR2 Inhibitor, in Patients with Metastatic Gastric Cancer.

PloS one

A phase 1 study of combined guadecitabine and cisplatin in platinum refractory germ cell cancer.

Cancer medicine

Avec: Costantine Albany , Zeeshan Fazal , Ratnakar Singh , Emmanuel Bikorimana , Nabil Adra , Nasser H Hanna , Lawrence H Einhorn , Susan M Perkins , George E Sandusky , Brock C Christensen , Harold Keer , Fang Fang , Kenneth P Nephew , Michael J Spinella

Epigenetic priming by hypomethylation enhances the immunogenic potential of tolinapant in T-cell lymphoma.

Cancer research communications

Avec: George A Ward , Zhiqiang Zhang , Simone Jueliger , Ilya S Potapov , Matthew P Davis , Adam R Boxall , Jason Taylor , Harold Keer , Andrea Biondo , John F Lyons , Martin Sims , Tomoko Smyth

Dose-escalation trial of combination dabrafenib, trametinib, and AT13387 in patients with BRAF-mutant solid tumors.

Cancer

Avec: Meghan J Mooradian , James M Cleary , Anita Giobbie-Hurder , Lancia N F Darville , Aparna Parikh , Elizabeth I Buchbinder , Justine V Cohen , Donald P Lawrence , Geoffrey I Shapiro , Harold Keer , Helen X Chen , Susan Percy Ivy , Keiran S M Smalley , John M Koomen , Ryan J Sullivan

Pharmacodynamic and Clinical Results from a Phase I/II Study of the HSP90 Inhibitor Onalespib in Combination with Abiraterone Acetate in Prostate Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Susan Slovin , Syed Hussain , Fred Saad , Jorge Garcia , Joel Picus , Roberta Ferraldeschi , Mateus Crespo , Penelope Flohr , Ruth Riisnaes , Chihche Lin , Harold Keer , Aram Oganesian , Paul Workman , Johann de Bono

Guadecitabine vs treatment choice in newly diagnosed acute myeloid leukemia: a global phase 3 randomized study.

Blood advances

Avec: Pierre Fenaux , Marco Gobbi , Patricia L Kropf , Jean-Pierre J Issa , Gail J Roboz , Jiri Mayer , Jürgen Krauter , Tadeusz Robak , Hagop Kantarjian , Jan Novak , Wieslaw W Jedrzejczak , Xavier Thomas , Mario Ojeda-Uribe , Yasushi Miyazaki , Yoo Hong Min , Su-Peng Yeh , Joseph Brandwein , Liana Gercheva-Kyuchukova , Judit Demeter , Elizabeth Griffiths , Karen Yee , Konstanze Döhner , Yong Hao , Harold Keer , Mohammad Azab , Hartmut Döhner

Oral decitabine/cedazuridine versus intravenous decitabine for acute myeloid leukaemia: A randomised, crossover, registration, pharmacokinetics study.

British journal of haematology

Avec: Klaus Geissler , Zdenek Koristek , Teresa Bernal Del Castillo , Jan Novák , Gabriela Rodríguez-Macías , Stephan K Metzelder , Arpad Illes , Jiří Mayer , Montserrat Arnan , Mary-Margaret Keating , Jürgen Krauter , Monia Lunghi , Nicola Stefano Fracchiolla , Uwe Platzbecker , Valeria Santini , Yuri Sano , Aram Oganesian , Harold Keer , Michael Lübbert

Réseau de co-auteurs

Aram Oganesian 5 collaborations

Simone Jueliger 4 collaborations

Mohammad Azab 3 collaborations

Roberta Ferraldeschi 3 collaborations

Kenneth P Nephew 2 collaborations

Yong Hao 2 collaborations

Matthew P Davis 2 collaborations

Tomoko Smyth 2 collaborations

Manish A Shah 2 collaborations

Zev A Wainberg 2 collaborations

Daniel V T Catenacci 2 collaborations

Howard S Hochster 2 collaborations

James Ford 2 collaborations

Pamela Kunz 2 collaborations

Fa-Chyi Lee 2 collaborations

Howard Kallender 2 collaborations

Fabiola Cecchi 2 collaborations

Daniel C Rabe 2 collaborations

Anne-Marie Martin 2 collaborations

Yuan Liu 2 collaborations

Robert Gagnon 2 collaborations

Peter Bonate 2 collaborations

Li Liu 2 collaborations

Tona Gilmer 2 collaborations

Donald P Bottaro 2 collaborations

Jürgen Krauter 2 collaborations

Amit M Oza 1 collaboration

Ursula A Matulonis 1 collaboration

Angeles Alvarez Secord 1 collaboration

John Nemunaitis 1 collaboration

Lynda D Roman 1 collaboration

Sarah P Blagden 1 collaboration

Susana Banerjee 1 collaboration

William P McGuire 1 collaboration

Sharad Ghamande 1 collaboration

Michael J Birrer 1 collaboration

Gini F Fleming 1 collaboration

Merry Jennifer Markham 1 collaboration

Hal W Hirte 1 collaboration

Diane M Provencher 1 collaboration

Bristi Basu 1 collaboration

Rebecca Kristeleit 1 collaboration

Deborah K Armstrong 1 collaboration

Benjamin Schwartz 1 collaboration

Patricia Braly 1 collaboration

Geoff D Hall 1 collaboration

Sue Naim 1 collaboration

Daniela Matei 1 collaboration

Manjusha Thakar 1 collaboration

Yue Hu 1 collaboration

Michael Morreale 1 collaboration

Lane Lerner 1 collaboration

Wan Ying Lin 1 collaboration

Rupashree Sen 1 collaboration

Yi Cai 1 collaboration

Enusha Karunasena 1 collaboration

Maya Thakar 1 collaboration

Soren Saggi 1 collaboration

Nita Ahuja 1 collaboration

Nicola Ferrari 1 collaboration

George Ward 1 collaboration

Christina Gewinner 1 collaboration

Harpreet Saini 1 collaboration

Joanne Munck 1 collaboration

John Lyons 1 collaboration

Martin J Sims 1 collaboration

Anoop Enjeti 1 collaboration

Asma Ashraf 1 collaboration

Vincent Caillet 1 collaboration

Arif Alam 1 collaboration

Jonathan Silar 1 collaboration

Francesco Castaldi 1 collaboration

Taleisha Paine 1 collaboration

Haley E Ramsey 1 collaboration

Agnieszka E Gorska 1 collaboration

Londa Fuller 1 collaboration

Maria Arrate 1 collaboration

Kelli Boyd 1 collaboration

Michael R Savona 1 collaboration

Monica M Mita 1 collaboration

Patricia M LoRusso 1 collaboration

Kyriakos P Papadopoulos 1 collaboration

Michael S Gordon 1 collaboration

Alain C Mita 1 collaboration

Xiang Yao Su 1 collaboration

Anthony W Tolcher 1 collaboration

Costantine Albany 1 collaboration

Zeeshan Fazal 1 collaboration

Ratnakar Singh 1 collaboration

Emmanuel Bikorimana 1 collaboration

Nabil Adra 1 collaboration

Nasser H Hanna 1 collaboration

Lawrence H Einhorn 1 collaboration

Susan M Perkins 1 collaboration

George E Sandusky 1 collaboration

Brock C Christensen 1 collaboration

Fang Fang 1 collaboration

Michael J Spinella 1 collaboration

George A Ward 1 collaboration

Zhiqiang Zhang 1 collaboration

Ilya S Potapov 1 collaboration

Adam R Boxall 1 collaboration

Jason Taylor 1 collaboration

Andrea Biondo 1 collaboration

John F Lyons 1 collaboration

Martin Sims 1 collaboration

Meghan J Mooradian 1 collaboration

James M Cleary 1 collaboration

Anita Giobbie-Hurder 1 collaboration

Lancia N F Darville 1 collaboration

Aparna Parikh 1 collaboration

Elizabeth I Buchbinder 1 collaboration

Justine V Cohen 1 collaboration

Donald P Lawrence 1 collaboration

Geoffrey I Shapiro 1 collaboration

Helen X Chen 1 collaboration

Susan Percy Ivy 1 collaboration

Keiran S M Smalley 1 collaboration

John M Koomen 1 collaboration

Ryan J Sullivan 1 collaboration

Susan Slovin 1 collaboration

Syed Hussain 1 collaboration

Fred Saad 1 collaboration

Jorge Garcia 1 collaboration

Joel Picus 1 collaboration

Mateus Crespo 1 collaboration

Penelope Flohr 1 collaboration

Ruth Riisnaes 1 collaboration

Chihche Lin 1 collaboration

Paul Workman 1 collaboration

Johann de Bono 1 collaboration

Pierre Fenaux 1 collaboration

Marco Gobbi 1 collaboration

Patricia L Kropf 1 collaboration

Jean-Pierre J Issa 1 collaboration

Gail J Roboz 1 collaboration

Jiri Mayer 1 collaboration

Tadeusz Robak 1 collaboration

Hagop Kantarjian 1 collaboration

Jan Novak 1 collaboration

Wieslaw W Jedrzejczak 1 collaboration

Xavier Thomas 1 collaboration

Mario Ojeda-Uribe 1 collaboration

Yasushi Miyazaki 1 collaboration

Yoo Hong Min 1 collaboration

Su-Peng Yeh 1 collaboration

Joseph Brandwein 1 collaboration

Liana Gercheva-Kyuchukova 1 collaboration

Judit Demeter 1 collaboration

Elizabeth Griffiths 1 collaboration

Karen Yee 1 collaboration

Konstanze Döhner 1 collaboration

Hartmut Döhner 1 collaboration

Klaus Geissler 1 collaboration

Zdenek Koristek 1 collaboration

Teresa Bernal Del Castillo 1 collaboration

Jan Novák 1 collaboration

Gabriela Rodríguez-Macías 1 collaboration

Stephan K Metzelder 1 collaboration

Arpad Illes 1 collaboration

Jiří Mayer 1 collaboration

Montserrat Arnan 1 collaboration

Mary-Margaret Keating 1 collaboration

Monia Lunghi 1 collaboration

Nicola Stefano Fracchiolla 1 collaboration

Uwe Platzbecker 1 collaboration

Valeria Santini 1 collaboration

Yuri Sano 1 collaboration

Michael Lübbert 1 collaboration