Helen Wheadon

Affiliations

School of Cancer Sciences, Paul O'Gorman Leukaemia Research Centre, Gartnavel General Hospital, University of Glasgow, Glasgow, G12 0YN, United Kingdom.

ORCID: http://orcid.org/0000-0001-9902-3170

Publications (14)

Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells.

Nature communications

Avec: Hannah Donnelly , Ewan Ross , Yinbo Xiao , Rio Hermantara , Aqeel F Taqi , W Sebastian Doherty-Boyd , Jennifer Cassels , Penelope M Tsimbouri , Karen M Dunn , Jodie Hay , Annie Cheng , R M Dominic Meek , Nikhil Jain , Christopher West , Helen Wheadon , Alison M Michie , Bruno Peault , Adam G West , Manuel Salmeron-Sanchez , Matthew J Dalby

Macrophages in Acute Myeloid Leukaemia: Significant Players in Therapy Resistance and Patient Outcomes.

Frontiers in cell and developmental biology

Avec: Katerina E Miari , Monica L Guzman , Helen Wheadon , Mark T S Williams

Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche.

Nature communications

Avec: Amy Dawson , Martha M Zarou , Bodhayan Prasad , Joana Bittencourt-Silvestre , Désirée Zerbst , Ekaterini Himonas , Ya-Ching Hsieh , Isabel van Loon , Giovanny Rodriguez Blanco , Angela Ianniciello , Zsombor Kerekes , Vaidehi Krishnan , Puneet Agarwal , Hassan Almasoudi , Laura McCluskey , Lisa E M Hopcroft , Mary T Scott , Pablo Baquero , Karen Dunn , David Vetrie , Mhairi Copland , Ravi Bhatia , Seth B Coffelt , Ong Sin Tiong , Helen Wheadon , Sara Zanivan , Kristina Kirschner , G Vignir Helgason

Inflammatory infiltration is associated with AR expression and poor prognosis in hormone naïve prostate cancer.

The Prostate

Avec: Milly McAllister , Vera Constâncio , Samantha Patek , Hao W G Gan , Peter Bailey , Helen Wheadon , Mark Underwood , Hing Leung , Joanne Edwards

BH3 mimetics in combination with nilotinib or ponatinib represent a promising therapeutic strategy in blast phase chronic myeloid leukemia.

Cell death discovery

Avec: Narissa Parry , Caroline Busch , Victoria Aßmann , Jennifer Cassels , Alan Hair , G Vignir Helgason , Helen Wheadon , Mhairi Copland

Overcoming BCR::ABL1 dependent and independent survival mechanisms in chronic myeloid leukaemia using a multi-kinase targeting approach.

Cell communication and signaling : CCS

Avec: Caroline Busch , Theresa Mulholland , Michele Zagnoni , Matthew Dalby , Catherine Berry , Helen Wheadon

The application of BH3 mimetics in myeloid leukemias.

Cell death & disease

Avec: Narissa Parry , Helen Wheadon , Mhairi Copland

Correction: CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy.

Leukemia

Avec: Ross Kinstrie , Gillian A Horne , Heather Morrison , David Irvine , Chinmay Munje , Eduardo Gómez Castañeda , Hothri A Moka , Karen Dunn , Jennifer E Cassels , Narissa Parry , Cassie J Clarke , Mary T Scott , Richard E Clark , Tessa L Holyoake , Helen Wheadon , Mhairi Copland

Interrogation of novel CDK2/9 inhibitor fadraciclib (CYC065) as a potential therapeutic approach for AML.

Cell death discovery

Avec: Wittawat Chantkran , Ya-Ching Hsieh , Daniella Zheleva , Sheelagh Frame , Helen Wheadon , Mhairi Copland

Using topic modeling to detect cellular crosstalk in scRNA-seq.

PLoS computational biology

Avec: Alexandrina Pancheva , Helen Wheadon , Simon Rogers , Thomas D Otto

CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy.

Leukemia

Avec: Ross Kinstrie , Gillian A Horne , Heather Morrison , David Irvine , Chinmay Munje , Eduardo Gómez Castañeda , Hothri A Moka , Karen Dunn , Jennifer E Cassels , Narissa Parry , Cassie J Clarke , Mary T Scott , Richard E Clark , Tessa L Holyoake , Helen Wheadon , Mhairi Copland

Bone marrow niche crosses paths with BMPs: a road to protection and persistence in CML.

Biochemical Society transactions

Avec: Caroline Busch , Helen Wheadon

Micro-environment alterations through time leading to myeloid malignancies.

British journal of pharmacology

Avec: Kudzai Nyamondo , Helen Wheadon

Complexities of modelling the bone marrow microenvironment to facilitate haematopoietic research.

Experimental hematology

Avec: Caroline Busch , Kudzai Nyamondo , Helen Wheadon

Réseau de co-auteurs

Mhairi Copland 6 collaborations

Narissa Parry 4 collaborations

Caroline Busch 4 collaborations

Mary T Scott 3 collaborations

Karen Dunn 3 collaborations

Jennifer Cassels 2 collaborations

Ya-Ching Hsieh 2 collaborations

G Vignir Helgason 2 collaborations

Ross Kinstrie 2 collaborations

Gillian A Horne 2 collaborations

Heather Morrison 2 collaborations

David Irvine 2 collaborations

Chinmay Munje 2 collaborations

Eduardo Gómez Castañeda 2 collaborations

Hothri A Moka 2 collaborations

Jennifer E Cassels 2 collaborations

Cassie J Clarke 2 collaborations

Richard E Clark 2 collaborations

Tessa L Holyoake 2 collaborations

Kudzai Nyamondo 2 collaborations

Hannah Donnelly 1 collaboration

Ewan Ross 1 collaboration

Yinbo Xiao 1 collaboration

Rio Hermantara 1 collaboration

Aqeel F Taqi 1 collaboration

W Sebastian Doherty-Boyd 1 collaboration

Penelope M Tsimbouri 1 collaboration

Karen M Dunn 1 collaboration

Jodie Hay 1 collaboration

Annie Cheng 1 collaboration

R M Dominic Meek 1 collaboration

Nikhil Jain 1 collaboration

Christopher West 1 collaboration

Alison M Michie 1 collaboration

Bruno Peault 1 collaboration

Adam G West 1 collaboration

Manuel Salmeron-Sanchez 1 collaboration

Matthew J Dalby 1 collaboration

Katerina E Miari 1 collaboration

Monica L Guzman 1 collaboration

Mark T S Williams 1 collaboration

Amy Dawson 1 collaboration

Martha M Zarou 1 collaboration

Bodhayan Prasad 1 collaboration

Joana Bittencourt-Silvestre 1 collaboration

Désirée Zerbst 1 collaboration

Ekaterini Himonas 1 collaboration

Isabel van Loon 1 collaboration

Giovanny Rodriguez Blanco 1 collaboration

Angela Ianniciello 1 collaboration

Zsombor Kerekes 1 collaboration

Vaidehi Krishnan 1 collaboration

Puneet Agarwal 1 collaboration

Hassan Almasoudi 1 collaboration

Laura McCluskey 1 collaboration

Lisa E M Hopcroft 1 collaboration

Pablo Baquero 1 collaboration

David Vetrie 1 collaboration

Ravi Bhatia 1 collaboration

Seth B Coffelt 1 collaboration

Ong Sin Tiong 1 collaboration

Sara Zanivan 1 collaboration

Kristina Kirschner 1 collaboration

Milly McAllister 1 collaboration

Vera Constâncio 1 collaboration

Samantha Patek 1 collaboration

Hao W G Gan 1 collaboration

Peter Bailey 1 collaboration

Mark Underwood 1 collaboration

Hing Leung 1 collaboration

Joanne Edwards 1 collaboration

Victoria Aßmann 1 collaboration

Alan Hair 1 collaboration

Theresa Mulholland 1 collaboration

Michele Zagnoni 1 collaboration

Matthew Dalby 1 collaboration

Catherine Berry 1 collaboration

Wittawat Chantkran 1 collaboration

Daniella Zheleva 1 collaboration

Sheelagh Frame 1 collaboration

Alexandrina Pancheva 1 collaboration

Simon Rogers 1 collaboration

Thomas D Otto 1 collaboration