Jaime F Modiano

Affiliations

Animal Cancer Care and Research Program, University of Minnesota, St. Paul, MN, USA; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.

Publications (29)

Ectodomain shedding by ADAM17 (a disintegrin and metalloproteinase 17) in canine neutrophils.

Veterinary immunology and immunopathology

Avec: Kristin M Snyder , Camille A McAloney , Joshua S Montel , Jaime F Modiano , Bruce Walcheck

S100A4 mRNA-protein relationship uncovered by measurement noise reduction.

Journal of molecular medicine (Berlin, Germany)

Avec: Angelos-Theodoros Athanasiou , Thomas Nussbaumer , Stefan Kummer , Martin Hofer , Iain G Johnston , Moritz Staltner , Daniela M Allmer , Milcah C Scott , Claus Vogl , Joelle M Fenger , Jaime F Modiano , Ingrid Walter , Ralf Steinborn

Blood and tissue biomarker analysis in dogs with osteosarcoma treated with palliative radiation and intra-tumoral autologous natural killer cell transfer.

PloS one

Avec: Sean J Judge , Mio Yanagisawa , Ian R Sturgill , Sarah B Bateni , Alicia A Gingrich , Jennifer A Foltz , Dean A Lee , Jaime F Modiano , Arta M Monjazeb , William T N Culp , Robert B Rebhun , William J Murphy , Michael S Kent , Robert J Canter

Examination of IgG Fc Receptor CD16A and CD64 Expression by Canine Leukocytes and Their ADCC Activity in Engineered NK Cells.

Frontiers in immunology

Avec: Robert Hullsiek , Yunfang Li , Kristin M Snyder , Sam Wang , Da Di , Antonella Borgatti , Chae Lee , Peter F Moore , Cong Zhu , Chiara Fattori , Jaime F Modiano , Jianming Wu , Bruce Walcheck

Evaluation of coated platelets, a subset of highly procoagulant platelets, in healthy dogs and dogs with neoplasia.

American journal of veterinary research

Avec: Kelly M Makielski , Leslie E Fox , Chad M Johannes , Aaron K Rendahl , Ashley J Schulte , Jong Hyuk Kim , Brian D Husbands , Jillian Z Walz , Michael S Henson , Jaime F Modiano , Dana N LeVine

Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human Angiosarcoma.

Molecular cancer research : MCR

Avec: Kate Megquier , Jason Turner-Maier , Ross Swofford , Jong-Hyuk Kim , Aaron L Sarver , Chao Wang , Sharadha Sakthikumar , Jeremy Johnson , Michele Koltookian , Mitzi Lewellen , Milcah C Scott , Ashley J Schulte , Luke Borst , Noriko Tonomura , Jessica Alfoldi , Corrie Painter , Rachael Thomas , Elinor K Karlsson , Matthew Breen , Jaime F Modiano , Ingegerd Elvers , Kerstin Lindblad-Toh

Retrospective evaluation of thrombocytopenia and tumor stage as prognostic indicators in dogs with splenic hemangiosarcoma.

Journal of the American Veterinary Medical Association

Avec: Alison R Masyr , Aaron K Rendahl , Amber L Winter , Antonella Borgatti , Jaime F Modiano

Comparative analysis of genome-wide DNA methylation identifies patterns that associate with conserved transcriptional programs in osteosarcoma.

Bone

Avec: Lauren J Mills , Milcah C Scott , Pankti Shah , Anne R Cunanan , Archana Deshpande , Benjamin Auch , Bridget Curtin , Kenneth B Beckman , Logan G Spector , Aaron L Sarver , Subbaya Subramanian , Todd A Richmond , Jaime F Modiano

Extracellular Vesicles Secreted by Tumor Cells Promote the Generation of Suppressive Monocytes.

ImmunoHorizons

Avec: Nhungoc Luong , Jennifer A Lenz , Jaime F Modiano , Julie K Olson

Distinct mechanisms of PTEN inactivation in dogs and humans highlight convergent molecular events that drive cell division in the pathogenesis of osteosarcoma.

Cancer genetics

Avec: Aaron L Sarver , Lauren J Mills , Kelly M Makielski , Nuri A Temiz , Jinhua Wang , Logan G Spector , Subbaya Subramanian , Jaime F Modiano

Isolation of Cancer-Derived Exosomes Using a Variety of Magnetic Nanostructures: From Fe

Nanomaterials (Basel, Switzerland)

Avec: Zohreh Nemati , Mohammad Reza Zamani Kouhpanji , Fang Zhou , Raja Das , Kelly Makielski , Joseph Um , Manh-Huong Phan , Alicia Muela , Ma Luisa Fdez-Gubieda , Rhonda R Franklin , Bethanie J H Stadler , Jaime F Modiano , Javier Alonso

A comparison of risk factors for metastasis at diagnosis in humans and dogs with osteosarcoma.

Cancer medicine

Avec: Brandon J Diessner , Tracy A Marko , Ruth M Scott , Andrea L Eckert , Kathleen M Stuebner , Ann E Hohenhaus , Kim A Selting , David A Largaespada , Jaime F Modiano , Logan G Spector

Characterization and Potential Applications of Dog Natural Killer Cells in Cancer Immunotherapy.

Journal of clinical medicine

Avec: Alicia A Gingrich , Jaime F Modiano , Robert J Canter

Neoadjuvant systemic oncolytic vesicular stomatitis virus is safe and may enhance long-term survivorship in dogs with naturally occurring osteosarcoma.

bioRxiv : the preprint server for biology

Avec: Kelly M Makielski , Aaron L Sarver , Michael S Henson , Kathleen M Stuebner , Antonella Borgatti , Lukkana Suksanpaisan , Caitlin Preusser , Alexandru-Flaviu Tabaran , Ingrid Cornax , M Gerard O'Sullivan , Andrea Chehadeh , Donna Groschen , Kelly Bergsrud , Sara Pracht , Amber Winter , Lauren J Mills , Marc D Schwabenlander , Melissa Wolfe , Michael A Farrar , Gary R Cutter , Joseph S Koopmeiners , Stephen J Russell , Jaime F Modiano , Shruthi Naik

Toxicity Profile of eBAT, a Bispecific Ligand-Targeted Toxin Directed to EGFR and uPAR, in Mice and a Clinical Dog Model.

Toxins

Avec: Rose H Dicovitsky , Jill T Schappa , Ashley J Schulte , Haeree P Lang , Ellen Kuerbitz , Sarah Roberts , Taylor A DePauw , Mitzi Lewellen , Amber L Winter , Kathy Stuebner , Michelle Buettner , Kelly Reid , Kelly Bergsrud , Sara Pracht , Andrea Chehadeh , Caitlin Feiock , M Gerard O'Sullivan , Tim Carlson , Alexandra R Armstrong , Danielle Meritet , Michael S Henson , Brenda J Weigel , Jaime F Modiano , Antonella Borgatti , Daniel A Vallera

Comparative Approach to the Temporo-Spatial Organization of the Tumor Microenvironment.

Frontiers in oncology

Avec: Kendall L Langsten , Jong Hyuk Kim , Aaron L Sarver , Mark Dewhirst , Jaime F Modiano

Bispecific Targeting of EGFR and Urokinase Receptor (uPAR) Using Ligand-Targeted Toxins in Solid Tumors.

Biomolecules

Avec: Felix Oh , Jaime F Modiano , Veronika Bachanova , Daniel A Vallera

Impact of repeated cycles of EGF bispecific angiotoxin (eBAT) administered at a reduced interval from doxorubicin chemotherapy in dogs with splenic haemangiosarcoma.

Veterinary and comparative oncology

Avec: Antonella Borgatti , Ann Fieberg , Amber L Winter , Kathleen Stuebner , Elizabeth Taras , Deborah Todhunter , Alison Masyr , Aaron Rendhal , Daniel A Vallera , Joseph S Koopmeiners , Jaime F Modiano

Risk Factors for Development of Canine and Human Osteosarcoma: A Comparative Review.

Veterinary sciences

Avec: Kelly M Makielski , Lauren J Mills , Aaron L Sarver , Michael S Henson , Logan G Spector , Shruthi Naik , Jaime F Modiano

Evolutionarily conserved resistance to phagocytosis observed in melanoma cells is insensitive to upregulation of pro-phagocytic signals and to CD47 blockade.

Melanoma research

Avec: Katie L Anderson , Kristin M Snyder , Daisuke Ito , Debra C Lins , Lauren J Mills , Kipp Weiskopf , Nan G Ring , Aaron M Ring , Yoji Shimizu , Matthew F Mescher , Irving L Weissman , Jaime F Modiano

Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions.

Molecular cancer research : MCR

Avec: Jong Hyuk Kim , Kate Megquier , Rachael Thomas , Aaron L Sarver , Jung Min Song , Yoon Tae Kim , Nuojin Cheng , Ashley J Schulte , Michael A Linden , Paari Murugan , LeAnn Oseth , Colleen L Forster , Ingegerd Elvers , Ross Swofford , Jason Turner-Maier , Elinor K Karlsson , Matthew Breen , Kerstin Lindblad-Toh , Jaime F Modiano

Expression and high levels of insertional polymorphism of an endogenous gammaretrovirus lineage in dogs.

PLoS genetics

Avec: Abigail S Jarosz , Amanda L Pendleton , Michael J Lashbrook , Erica Cech , Madison Altieri , Austin Kunch , Jaime F Modiano , Julia V Halo

Increased risk of cancer in dogs and humans: a consequence of recent extension of lifespan beyond evolutionarily-determined limitations?

Aging and cancer

Avec: Aaron L Sarver , Kelly M Makielski , Taylor A DePauw , Ashley J Schulte , Jaime F Modiano

Bioapplications of Magnetic Nanowires: Barcodes, Biocomposites, Heaters.

IEEE transactions on magnetics

Avec: Mohammad Reza Zamani Kouhpanji , Yali Zhang , Joseph Um , Kartihik Srinivasan , Anirudh Sharma , Daniel Shore , Zhe Gao , Yicong Chen , Allison Harpel , Zohreh Nemati Porshokouh , Thomas E Gage , Oana Dragos-Pinzaru , Ibro Tabakovic , P B Visscher , John Bischof , Jaime F Modiano , Rhonda Franklin , Bethanie J H Stadler

Hemangiosarcoma Cells Promote Conserved Host-Derived Hematopoietic Expansion.

Cancer research communications

Avec: Jong Hyuk Kim , Ashley J Schulte , Aaron L Sarver , Donghee Lee , Mathew G Angelos , Aric M Frantz , Colleen L Forster , Timothy D O'Brien , Ingrid Cornax , M Gerard O'Sullivan , Nuojin Cheng , Mitzi Lewellen , LeAnn Oseth , Sunil Kumar , Susan Bullman , Chandra Sekhar Pedamallu , Sagar M Goyal , Matthew Meyerson , Troy C Lund , Matthew Breen , Kerstin Lindblad-Toh , Erin B Dickerson , Dan S Kaufman , Jaime F Modiano

Development of an exosomal gene signature to detect residual disease in dogs with osteosarcoma using a novel xenograft platform and machine learning.

Laboratory investigation; a journal of technical methods and pathology

Avec: Kelly M Makielski , Alicia J Donnelly , Ali Khammanivong , Milcah C Scott , Andrea R Ortiz , Dana C Galvan , Hirotaka Tomiyasu , Clarissa Amaya , Kristin A Ward , Alexa Montoya , John R Garbe , Lauren J Mills , Gary R Cutter , Joelle M Fenger , William C Kisseberth , Timothy D O'Brien , Brenda J Weigel , Logan G Spector , Brad A Bryan , Subbaya Subramanian , Jaime F Modiano

Anti-Cancer Activity of PAK4/NAMPT Inhibitor and Programmed Cell Death Protein-1 Antibody in Kidney Cancer.

Kidney360

Avec: Josephine F Trott , Omran Abu Aboud , Bridget McLaughlin , Katie L Anderson , Jaime F Modiano , Kyoungmi Kim , Kuang-Yu Jen , William Senapedis , Hua Chang , Yosef Landesman , Erkan Baloglu , Roberto Pili , Robert H Weiss

Targeted sequencing of candidate gene regions for myelofibrosis in dogs.

Journal of veterinary internal medicine

Avec: Amelia G Campbell , Davis M Seelig , Joan D Beckman , Katie M Minor , Daniel A Heinrich , Steven G Friedenberg , Jaime F Modiano , Eva Furrow

Neoadjuvant systemic oncolytic vesicular stomatitis virus is safe and may enhance long-term survivorship in dogs with naturally occurring osteosarcoma.

Molecular therapy oncolytics

Réseau de co-auteurs

Aaron L Sarver 10 collaborations

Kelly M Makielski 7 collaborations

Lauren J Mills 7 collaborations

Antonella Borgatti 6 collaborations

Ashley J Schulte 6 collaborations

Michael S Henson 5 collaborations

Logan G Spector 5 collaborations

Milcah C Scott 4 collaborations

Jong Hyuk Kim 4 collaborations

M Gerard O'Sullivan 4 collaborations

Kristin M Snyder 3 collaborations

Mitzi Lewellen 3 collaborations

Matthew Breen 3 collaborations

Kerstin Lindblad-Toh 3 collaborations

Amber L Winter 3 collaborations

Subbaya Subramanian 3 collaborations

Kathleen M Stuebner 3 collaborations

Ingrid Cornax 3 collaborations

Andrea Chehadeh 3 collaborations

Kelly Bergsrud 3 collaborations

Sara Pracht 3 collaborations

Gary R Cutter 3 collaborations

Joseph S Koopmeiners 3 collaborations

Shruthi Naik 3 collaborations

Daniel A Vallera 3 collaborations

Bruce Walcheck 2 collaborations

Joelle M Fenger 2 collaborations

Alicia A Gingrich 2 collaborations

Robert J Canter 2 collaborations

Aaron K Rendahl 2 collaborations

Kate Megquier 2 collaborations

Jason Turner-Maier 2 collaborations

Ross Swofford 2 collaborations

Rachael Thomas 2 collaborations

Elinor K Karlsson 2 collaborations

Ingegerd Elvers 2 collaborations

Mohammad Reza Zamani Kouhpanji 2 collaborations

Joseph Um 2 collaborations

Bethanie J H Stadler 2 collaborations

Lukkana Suksanpaisan 2 collaborations

Caitlin Preusser 2 collaborations

Alexandru-Flaviu Tabaran 2 collaborations

Donna Groschen 2 collaborations

Amber Winter 2 collaborations

Marc D Schwabenlander 2 collaborations

Melissa Wolfe 2 collaborations

Michael A Farrar 2 collaborations

Stephen J Russell 2 collaborations

Taylor A DePauw 2 collaborations

Brenda J Weigel 2 collaborations

Katie L Anderson 2 collaborations

Nuojin Cheng 2 collaborations

LeAnn Oseth 2 collaborations

Colleen L Forster 2 collaborations

Timothy D O'Brien 2 collaborations

Camille A McAloney 1 collaboration

Joshua S Montel 1 collaboration

Angelos-Theodoros Athanasiou 1 collaboration

Thomas Nussbaumer 1 collaboration

Stefan Kummer 1 collaboration

Martin Hofer 1 collaboration

Iain G Johnston 1 collaboration

Moritz Staltner 1 collaboration

Daniela M Allmer 1 collaboration

Claus Vogl 1 collaboration

Ingrid Walter 1 collaboration

Ralf Steinborn 1 collaboration

Sean J Judge 1 collaboration

Mio Yanagisawa 1 collaboration

Ian R Sturgill 1 collaboration

Sarah B Bateni 1 collaboration

Jennifer A Foltz 1 collaboration

Dean A Lee 1 collaboration

Arta M Monjazeb 1 collaboration

William T N Culp 1 collaboration

Robert B Rebhun 1 collaboration

William J Murphy 1 collaboration

Michael S Kent 1 collaboration

Robert Hullsiek 1 collaboration

Yunfang Li 1 collaboration

Sam Wang 1 collaboration

Da Di 1 collaboration

Chae Lee 1 collaboration

Peter F Moore 1 collaboration

Cong Zhu 1 collaboration

Chiara Fattori 1 collaboration

Jianming Wu 1 collaboration

Leslie E Fox 1 collaboration

Chad M Johannes 1 collaboration

Brian D Husbands 1 collaboration

Jillian Z Walz 1 collaboration

Dana N LeVine 1 collaboration

Jong-Hyuk Kim 1 collaboration

Chao Wang 1 collaboration

Sharadha Sakthikumar 1 collaboration

Jeremy Johnson 1 collaboration

Michele Koltookian 1 collaboration

Luke Borst 1 collaboration

Noriko Tonomura 1 collaboration

Jessica Alfoldi 1 collaboration

Corrie Painter 1 collaboration

Alison R Masyr 1 collaboration

Pankti Shah 1 collaboration

Anne R Cunanan 1 collaboration

Archana Deshpande 1 collaboration

Benjamin Auch 1 collaboration

Bridget Curtin 1 collaboration

Kenneth B Beckman 1 collaboration

Todd A Richmond 1 collaboration

Nhungoc Luong 1 collaboration

Jennifer A Lenz 1 collaboration

Julie K Olson 1 collaboration

Nuri A Temiz 1 collaboration

Jinhua Wang 1 collaboration

Zohreh Nemati 1 collaboration

Fang Zhou 1 collaboration

Raja Das 1 collaboration

Kelly Makielski 1 collaboration

Manh-Huong Phan 1 collaboration

Alicia Muela 1 collaboration

Ma Luisa Fdez-Gubieda 1 collaboration

Rhonda R Franklin 1 collaboration

Javier Alonso 1 collaboration

Brandon J Diessner 1 collaboration

Tracy A Marko 1 collaboration

Ruth M Scott 1 collaboration

Andrea L Eckert 1 collaboration

Ann E Hohenhaus 1 collaboration

Kim A Selting 1 collaboration

David A Largaespada 1 collaboration

Rose H Dicovitsky 1 collaboration

Jill T Schappa 1 collaboration

Haeree P Lang 1 collaboration

Ellen Kuerbitz 1 collaboration

Sarah Roberts 1 collaboration

Kathy Stuebner 1 collaboration

Michelle Buettner 1 collaboration

Kelly Reid 1 collaboration

Caitlin Feiock 1 collaboration

Tim Carlson 1 collaboration

Alexandra R Armstrong 1 collaboration

Danielle Meritet 1 collaboration

Kendall L Langsten 1 collaboration

Mark Dewhirst 1 collaboration

Felix Oh 1 collaboration

Veronika Bachanova 1 collaboration

Ann Fieberg 1 collaboration

Kathleen Stuebner 1 collaboration

Elizabeth Taras 1 collaboration

Deborah Todhunter 1 collaboration

Alison Masyr 1 collaboration

Aaron Rendhal 1 collaboration

Daisuke Ito 1 collaboration

Debra C Lins 1 collaboration

Kipp Weiskopf 1 collaboration

Nan G Ring 1 collaboration

Aaron M Ring 1 collaboration

Yoji Shimizu 1 collaboration

Matthew F Mescher 1 collaboration

Irving L Weissman 1 collaboration

Jung Min Song 1 collaboration

Yoon Tae Kim 1 collaboration

Michael A Linden 1 collaboration

Paari Murugan 1 collaboration

Abigail S Jarosz 1 collaboration

Amanda L Pendleton 1 collaboration

Michael J Lashbrook 1 collaboration

Erica Cech 1 collaboration

Madison Altieri 1 collaboration

Austin Kunch 1 collaboration

Julia V Halo 1 collaboration

Yali Zhang 1 collaboration

Kartihik Srinivasan 1 collaboration

Anirudh Sharma 1 collaboration

Daniel Shore 1 collaboration

Zhe Gao 1 collaboration

Yicong Chen 1 collaboration

Allison Harpel 1 collaboration

Zohreh Nemati Porshokouh 1 collaboration

Thomas E Gage 1 collaboration

Oana Dragos-Pinzaru 1 collaboration

Ibro Tabakovic 1 collaboration

P B Visscher 1 collaboration

John Bischof 1 collaboration

Rhonda Franklin 1 collaboration

Donghee Lee 1 collaboration

Mathew G Angelos 1 collaboration

Aric M Frantz 1 collaboration

Sunil Kumar 1 collaboration

Susan Bullman 1 collaboration

Chandra Sekhar Pedamallu 1 collaboration

Sagar M Goyal 1 collaboration

Matthew Meyerson 1 collaboration

Troy C Lund 1 collaboration

Erin B Dickerson 1 collaboration

Dan S Kaufman 1 collaboration

Alicia J Donnelly 1 collaboration

Ali Khammanivong 1 collaboration

Andrea R Ortiz 1 collaboration

Dana C Galvan 1 collaboration

Hirotaka Tomiyasu 1 collaboration

Clarissa Amaya 1 collaboration

Kristin A Ward 1 collaboration

Alexa Montoya 1 collaboration

John R Garbe 1 collaboration

William C Kisseberth 1 collaboration

Brad A Bryan 1 collaboration

Josephine F Trott 1 collaboration

Omran Abu Aboud 1 collaboration

Bridget McLaughlin 1 collaboration

Kyoungmi Kim 1 collaboration

Kuang-Yu Jen 1 collaboration

William Senapedis 1 collaboration

Hua Chang 1 collaboration

Yosef Landesman 1 collaboration

Erkan Baloglu 1 collaboration

Roberto Pili 1 collaboration

Robert H Weiss 1 collaboration

Amelia G Campbell 1 collaboration

Davis M Seelig 1 collaboration

Joan D Beckman 1 collaboration

Katie M Minor 1 collaboration

Daniel A Heinrich 1 collaboration

Steven G Friedenberg 1 collaboration

Eva Furrow 1 collaboration