Lara Bossini-Castillo

Affiliations
  • Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.

Publications (20)

Immune disease variants modulate gene expression in regulatory CD4

Cell genomics
Avec: Lara Bossini-Castillo , Dafni A Glinos , Natalia Kunowska , Gosia Golda , Abigail A Lamikanra , Michaela Spitzer , Blagoje Soskic , Eddie Cano-Gamez , Deborah J Smyth , Claire Cattermole , Kaur Alasoo , Alice Mann , Kousik Kundu , Anna Lorenc , Nicole Soranzo , Ian Dunham , David J Roberts , Gosia Trynka

Immune and spermatogenesis-related loci are involved in the development of extreme patterns of male infertility.

Communications biology
Avec: Miriam Cerván-Martín , Frank Tüttelmann , Alexandra M Lopes , Lara Bossini-Castillo , Rocío Rivera-Egea , Nicolás Garrido , Saturnino Lujan , Gema Romeu , Samuel Santos-Ribeiro , José A Castilla , M Carmen Gonzalvo , Ana Clavero , Vicente Maldonado , F Javier Vicente , Sara González-Muñoz , Andrea Guzmán-Jiménez , Miguel Burgos , Rafael Jiménez , Alberto Pacheco , Cristina González , Susana Gómez , David Amorós , Jesus Aguilar , Fernando Quintana , Carlos Calhaz-Jorge , Ana Aguiar , Joaquim Nunes , Sandra Sousa , Isabel Pereira , Maria Graça Pinto , Sónia Correia , Josvany Sánchez-Curbelo , Olga López-Rodrigo , Javier Martín , Iris Pereira-Caetano , Patricia I Marques , Filipa Carvalho , Alberto Barros , Jörg Gromoll , Lluís Bassas , Susana Seixas , João Gonçalves , Sara Larriba , Sabine Kliesch , Rogelio J Palomino-Morales , F David Carmona

Celiac Disease Is a Risk Factor for Mature T and NK Cell Lymphoma: A Mendelian Randomization Study.

International journal of molecular sciences
Avec: Rafael Martín-Masot , Marta Herrador-López , Víctor Manuel Navas-López , Francisco David Carmona , Teresa Nestares , Lara Bossini-Castillo

Genomic Risk Score impact on susceptibility to systemic sclerosis.

Annals of the rheumatic diseases
Avec: Lara Bossini-Castillo , Gonzalo Villanueva-Martin , Martin Kerick , Marialbert Acosta-Herrera , Elena López-Isac , Carmen P Simeón , Norberto Ortego-Centeno , Shervin Assassi , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Nicolas Hunzelmann , Armando Gabrielli , J K de Vries-Bouwstra , Yannick Allanore , Carmen Fonseca , Christopher P Denton , Timothy Rdj Radstake , Marta Eugenia Alarcón-Riquelme , Lorenzo Beretta , Maureen D Mayes , Javier Martin

Effect and in silico characterization of genetic variants associated with severe spermatogenic disorders in a large Iberian cohort.

Andrology
Avec: Miriam Cerván-Martín , Lara Bossini-Castillo , Rocío Rivera-Egea , Nicolás Garrido , Saturnino Luján , Gema Romeu , Samuel Santos-Ribeiro , Auteur inconnu , José A Castilla , María Del Carmen Gonzalvo , Ana Clavero , Francisco Javier Vicente , Andrea Guzmán-Jiménez , Miguel Burgos , Francisco Javier Barrionuevo , Rafael Jiménez , Josvany Sánchez-Curbelo , Olga López-Rodrigo , María Fernanda Peraza , Iris Pereira-Caetano , Patrícia Isabel Marques , Filipa Carvalho , Alberto Barros , Lluís Bassas , Susana Seixas , João Gonçalves , Sara Larriba , Alexandra Manuel Lopes , Francisco David Carmona , Rogelio Jesús Palomino-Morales

Immune disease risk variants regulate gene expression dynamics during CD4

Nature genetics
Avec: Blagoje Soskic , Eddie Cano-Gamez , Deborah J Smyth , Kirsty Ambridge , Ziying Ke , Julie C Matte , Lara Bossini-Castillo , Joanna Kaplanis , Lucia Ramirez-Navarro , Anna Lorenc , Nikolina Nakic , Jorge Esparza-Gordillo , Wendy Rowan , David Wille , David F Tough , Paola G Bronson , Gosia Trynka

A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by T

Nature
Avec: Rabab Nasrallah , Charlotte J Imianowski , Lara Bossini-Castillo , Francis M Grant , Mikail Dogan , Lindsey Placek , Lina Kozhaya , Paula Kuo , Firas Sadiyah , Sarah K Whiteside , Maxwell R Mumbach , Dafni Glinos , Panagiota Vardaka , Carly E Whyte , Teresa Lozano , Toshitsugu Fujita , Hodaka Fujii , Adrian Liston , Simon Andrews , Adeline Cozzani , Jie Yang , Suman Mitra , Enrico Lugli , Howard Y Chang , Derya Unutmaz , Gosia Trynka , Rahul Roychoudhuri

Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk.

Human molecular genetics
Avec: Jennie G Pouget , Auteur inconnu , Buhm Han , Yang Wu , Emmanuel Mignot , Hanna M Ollila , Jonathan Barker , Sarah Spain , Nick Dand , Richard Trembath , Javier Martin , Maureen D Mayes , Lara Bossini-Castillo , Elena López-Isac , Ying Jin , Stephanie A Santorico , Richard A Spritz , Hakon Hakonarson , Constantin Polychronakos , Soumya Raychaudhuri , Jo Knight

Evaluation of Male Fertility-Associated Loci in a European Population of Patients with Severe Spermatogenic Impairment.

Journal of personalized medicine
Avec: Miriam Cerván-Martín , Lara Bossini-Castillo , Rocío Rivera-Egea , Nicolás Garrido , Saturnino Luján , Gema Romeu , Samuel Santos-Ribeiro , Ivirma Group , Lisbon Clinical Group , José A Castilla , M Carmen Gonzalvo , Ana Clavero , F Javier Vicente , Andrea Guzmán-Jiménez , Cláudia Costa , Inés Llinares-Burguet , Chiranan Khantham , Miguel Burgos , Francisco J Barrionuevo , Rafael Jiménez , Josvany Sánchez-Curbelo , Olga López-Rodrigo , M Fernanda Peraza , Iris Pereira-Caetano , Patricia I Marques , Filipa Carvalho , Alberto Barros , Lluís Bassas , Susana Seixas , João Gonçalves , Sara Larriba , Alexandra M Lopes , Rogelio J Palomino-Morales , F David Carmona

Recent advances in elucidating the genetic basis of systemic sclerosis.

Current opinion in rheumatology
Avec: Gonzalo Villanueva-Martín , Javier Martín , Lara Bossini-Castillo

Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases.

Nature genetics
Avec: Blagoje Soskic , Eddie Cano-Gamez , Deborah J Smyth , Wendy C Rowan , Nikolina Nakic , Jorge Esparza-Gordillo , Lara Bossini-Castillo , David F Tough , Christopher G C Larminie , Paola G Bronson , David Willé , Gosia Trynka

GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways.

Nature communications
Avec: Elena López-Isac , Marialbert Acosta-Herrera , Martin Kerick , Shervin Assassi , Ansuman T Satpathy , Jeffrey Granja , Maxwell R Mumbach , Lorenzo Beretta , Carmen P Simeón , Patricia Carreira , Norberto Ortego-Centeno , Ivan Castellvi , Lara Bossini-Castillo , F David Carmona , Gisela Orozco , Nicolas Hunzelmann , Jörg H W Distler , Andre Franke , Claudio Lunardi , Gianluca Moroncini , Armando Gabrielli , Jeska de Vries-Bouwstra , Cisca Wijmenga , Bobby P C Koeleman , Annika Nordin , Leonid Padyukov , Anna-Maria Hoffmann-Vold , Benedicte Lie , Auteur inconnu , Susanna Proudman , Wendy Stevens , Mandana Nikpour , Auteur inconnu , Timothy Vyse , Ariane L Herrick , Jane Worthington , Christopher P Denton , Yannick Allanore , Matthew A Brown , Timothy R D J Radstake , Carmen Fonseca , Howard Y Chang , Maureen D Mayes , Javier Martin

The Effect of Body Fat Distribution on Systemic Sclerosis.

Journal of clinical medicine
Avec: Gonzalo Villanueva-Martin , Marialbert Acosta-Herrera , Martin Kerick , Elena López-Isac , Carmen P Simeón , José L Callejas , Shervin Assassi , Lorenzo Beretta , International SSc Group , Australian Scleroderma Interest Group Asig , Yannick Allanore , Susanna M Proudman , Mandana Nikpour , Carmen Fonseca , Christopher P Denton , Timothy R D J Radstake , Maureen D Mayes , Xia Jiang , Javier Martin , Lara Bossini-Castillo

Comprehensive Evaluation of the Genetic Basis of Keratoconus: New Perspectives for Clinical Translation.

Investigative ophthalmology & visual science
Avec: Miriam Cerván-Martín , Inmaculada Higueras-Serrano , Sara González-Muñoz , Andrea Guzmán-Jiménez , Blas Chaves-Urbano , Rogelio J Palomino-Morales , Arancha Poo-López , Luis Fernández-Vega-Cueto , Jesús Merayo-Lloves , Ignacio Alcalde , Lara Bossini-Castillo , F David Carmona

Low RUNX3 expression alters dendritic cell function in patients with systemic sclerosis and contributes to enhanced fibrosis.

Annals of the rheumatic diseases
Avec: Alsya J Affandi , Tiago Carvalheiro , Andrea Ottria , Jasper Ca Broen , Lara Bossini-Castillo , Ralph G Tieland , Lenny van Bon , Eleni Chouri , Marzia Rossato , Jorre S Mertens , Samuel Garcia , Aridaman Pandit , Laurie Mg de Kroon , Romy B Christmann , Javier Martin , Joel Ag van Roon , Timothy Rdj Radstake , Wioleta Marut

Common genetic variation in KATNAL1 non-coding regions is involved in the susceptibility to severe phenotypes of male infertility.

Andrology
Avec: Miriam Cerván-Martín , Lara Bossini-Castillo , Andrea Guzmán-Jiménez , Rocío Rivera-Egea , Nicolás Garrido , Saturnino Lujan , Gema Romeu , Samuel Santos-Ribeiro , Auteur inconnu , Auteur inconnu , José Antonio Castilla , María Del Carmen Gonzalvo , Ana Clavero , Vicente Maldonado , Francisco Javier Vicente , Miguel Burgos , Rafael Jiménez , Sara González-Muñoz , Josvany Sánchez-Curbelo , Olga López-Rodrigo , Iris Pereira-Caetano , Patricia Isabel Marques , Filipa Carvalho , Alberto Barros , Lluís Bassas , Susana Seixas , João Gonçalves , Sara Larriba , Alexandra Manuel Lopes , Rogelio Jesús Palomino-Morales , Francisco David Carmona

Genome-wide compound heterozygote analysis highlights DPY19L2 alleles in a non-consanguineous Spanish family with total globozoospermia.

Reproductive biomedicine online
Avec: Olga López-Rodrigo , Lara Bossini-Castillo , F David Carmona , Lluís Bassas , Sara Larriba

Common Variation in the PIN1 Locus Increases the Genetic Risk to Suffer from Sertoli Cell-Only Syndrome.

Journal of personalized medicine
Avec: Miriam Cerván-Martín , Lara Bossini-Castillo , Andrea Guzmán-Jimenez , Rocío Rivera-Egea , Nicolás Garrido , Saturnino Luján , Gema Romeu , Samuel Santos-Ribeiro , Ivirma Group , Lisbon Clinical Group , José A Castilla , M Carmen Gonzalvo , Ana Clavero , F Javier Vicente , Vicente Maldonado , Sara González-Muñoz , Inmaculada Rodríguez-Martín , Miguel Burgos , Rafael Jiménez , Maria Graça Pinto , Isabel Pereira , Joaquim Nunes , Josvany Sánchez-Curbelo , Olga López-Rodrigo , Iris Pereira-Caetano , Patricia Isabel Marques , Filipa Carvalho , Alberto Barros , Lluís Bassas , Susana Seixas , João Gonçalves , Sara Larriba , Alexandra M Lopes , F David Carmona , Rogelio J Palomino-Morales

Non-classical circulating monocytes expressing high levels of microsomal prostaglandin E2 synthase-1 tag an aberrant IFN-response in systemic sclerosis.

Journal of autoimmunity
Avec: Gonzalo Villanueva-Martin , Marialbert Acosta-Herrera , Elio G Carmona , Martin Kerick , Norberto Ortego-Centeno , Jose Luis Callejas-Rubio , Norbert Mages , Sven Klages , Stefan Börno , Bernd Timmermann , Lara Bossini-Castillo , Javier Martin

Changes in environmental exposures over decades may influence the genetic architecture of severe spermatogenic failure.

Human reproduction (Oxford, England)
Avec: Miriam Cerván-Martín , Sara González-Muñoz , Andrea Guzmán-Jiménez , Inmaculada Higueras-Serrano , José A Castilla , Nicolás Garrido , Saturnino Luján , Lluís Bassas , Susana Seixas , João Gonçalves , Alexandra M Lopes , Sara Larriba , Rogelio J Palomino-Morales , Lara Bossini-Castillo , F David Carmona

Réseau de co-auteurs

None None 10 collaborations
Miriam Cerván-Martín 7 collaborations
Lluís Bassas 7 collaborations
Sara Larriba 7 collaborations
F David Carmona 7 collaborations
Nicolás Garrido 6 collaborations
Andrea Guzmán-Jiménez 6 collaborations
Olga López-Rodrigo 6 collaborations
Susana Seixas 6 collaborations
João Gonçalves 6 collaborations
Javier Martin 6 collaborations
Rocío Rivera-Egea 5 collaborations
Gema Romeu 5 collaborations
Samuel Santos-Ribeiro 5 collaborations
José A Castilla 5 collaborations
Ana Clavero 5 collaborations
Sara González-Muñoz 5 collaborations
Miguel Burgos 5 collaborations
Rafael Jiménez 5 collaborations
Josvany Sánchez-Curbelo 5 collaborations
Iris Pereira-Caetano 5 collaborations
Filipa Carvalho 5 collaborations
Alberto Barros 5 collaborations
Rogelio J Palomino-Morales 5 collaborations
Gosia Trynka 4 collaborations
Alexandra M Lopes 4 collaborations
Martin Kerick 4 collaborations
Marialbert Acosta-Herrera 4 collaborations
Elena López-Isac 4 collaborations
Maureen D Mayes 4 collaborations
Saturnino Luján 4 collaborations
Blagoje Soskic 3 collaborations
Eddie Cano-Gamez 3 collaborations
Deborah J Smyth 3 collaborations
M Carmen Gonzalvo 3 collaborations
Vicente Maldonado 3 collaborations
F Javier Vicente 3 collaborations
Francisco David Carmona 3 collaborations
Gonzalo Villanueva-Martin 3 collaborations
Carmen P Simeón 3 collaborations
Norberto Ortego-Centeno 3 collaborations
Shervin Assassi 3 collaborations
Yannick Allanore 3 collaborations
Carmen Fonseca 3 collaborations
Christopher P Denton 3 collaborations
Lorenzo Beretta 3 collaborations
Anna Lorenc 2 collaborations
Saturnino Lujan 2 collaborations
Joaquim Nunes 2 collaborations
Isabel Pereira 2 collaborations
Maria Graça Pinto 2 collaborations
Javier Martín 2 collaborations
Patricia I Marques 2 collaborations
Nicolas Hunzelmann 2 collaborations
Armando Gabrielli 2 collaborations
Timothy Rdj Radstake 2 collaborations
María Del Carmen Gonzalvo 2 collaborations
Francisco Javier Vicente 2 collaborations
Alexandra Manuel Lopes 2 collaborations
Rogelio Jesús Palomino-Morales 2 collaborations
Nikolina Nakic 2 collaborations
Jorge Esparza-Gordillo 2 collaborations
David F Tough 2 collaborations
Paola G Bronson 2 collaborations
Maxwell R Mumbach 2 collaborations
Howard Y Chang 2 collaborations
None Ivirma Group 2 collaborations
None Lisbon Clinical Group 2 collaborations
Mandana Nikpour 2 collaborations
Timothy R D J Radstake 2 collaborations
Inmaculada Higueras-Serrano 2 collaborations
Patricia Isabel Marques 2 collaborations
Dafni A Glinos 1 collaboration
Natalia Kunowska 1 collaboration
Gosia Golda 1 collaboration
Abigail A Lamikanra 1 collaboration
Michaela Spitzer 1 collaboration
Claire Cattermole 1 collaboration
Kaur Alasoo 1 collaboration
Alice Mann 1 collaboration
Kousik Kundu 1 collaboration
Nicole Soranzo 1 collaboration
Ian Dunham 1 collaboration
David J Roberts 1 collaboration
Frank Tüttelmann 1 collaboration
Alberto Pacheco 1 collaboration
Cristina González 1 collaboration
Susana Gómez 1 collaboration
David Amorós 1 collaboration
Jesus Aguilar 1 collaboration
Fernando Quintana 1 collaboration
Carlos Calhaz-Jorge 1 collaboration
Ana Aguiar 1 collaboration
Sandra Sousa 1 collaboration
Sónia Correia 1 collaboration
Jörg Gromoll 1 collaboration
Sabine Kliesch 1 collaboration
Rafael Martín-Masot 1 collaboration
Marta Herrador-López 1 collaboration
Víctor Manuel Navas-López 1 collaboration
Teresa Nestares 1 collaboration
J K de Vries-Bouwstra 1 collaboration
Marta Eugenia Alarcón-Riquelme 1 collaboration
Francisco Javier Barrionuevo 1 collaboration
María Fernanda Peraza 1 collaboration
Patrícia Isabel Marques 1 collaboration
Kirsty Ambridge 1 collaboration
Ziying Ke 1 collaboration
Julie C Matte 1 collaboration
Joanna Kaplanis 1 collaboration
Lucia Ramirez-Navarro 1 collaboration
Wendy Rowan 1 collaboration
David Wille 1 collaboration
Rabab Nasrallah 1 collaboration
Charlotte J Imianowski 1 collaboration
Francis M Grant 1 collaboration
Mikail Dogan 1 collaboration
Lindsey Placek 1 collaboration
Lina Kozhaya 1 collaboration
Paula Kuo 1 collaboration
Firas Sadiyah 1 collaboration
Sarah K Whiteside 1 collaboration
Dafni Glinos 1 collaboration
Panagiota Vardaka 1 collaboration
Carly E Whyte 1 collaboration
Teresa Lozano 1 collaboration
Toshitsugu Fujita 1 collaboration
Hodaka Fujii 1 collaboration
Adrian Liston 1 collaboration
Simon Andrews 1 collaboration
Adeline Cozzani 1 collaboration
Jie Yang 1 collaboration
Suman Mitra 1 collaboration
Enrico Lugli 1 collaboration
Derya Unutmaz 1 collaboration
Rahul Roychoudhuri 1 collaboration
Jennie G Pouget 1 collaboration
Buhm Han 1 collaboration
Yang Wu 1 collaboration
Emmanuel Mignot 1 collaboration
Hanna M Ollila 1 collaboration
Jonathan Barker 1 collaboration
Sarah Spain 1 collaboration
Nick Dand 1 collaboration
Richard Trembath 1 collaboration
Ying Jin 1 collaboration
Stephanie A Santorico 1 collaboration
Richard A Spritz 1 collaboration
Hakon Hakonarson 1 collaboration
Constantin Polychronakos 1 collaboration
Soumya Raychaudhuri 1 collaboration
Jo Knight 1 collaboration
Cláudia Costa 1 collaboration
Inés Llinares-Burguet 1 collaboration
Chiranan Khantham 1 collaboration
Francisco J Barrionuevo 1 collaboration
M Fernanda Peraza 1 collaboration
Gonzalo Villanueva-Martín 1 collaboration
Wendy C Rowan 1 collaboration
Christopher G C Larminie 1 collaboration
David Willé 1 collaboration
Ansuman T Satpathy 1 collaboration
Jeffrey Granja 1 collaboration
Patricia Carreira 1 collaboration
Ivan Castellvi 1 collaboration
Gisela Orozco 1 collaboration
Jörg H W Distler 1 collaboration
Andre Franke 1 collaboration
Claudio Lunardi 1 collaboration
Gianluca Moroncini 1 collaboration
Jeska de Vries-Bouwstra 1 collaboration
Cisca Wijmenga 1 collaboration
Bobby P C Koeleman 1 collaboration
Annika Nordin 1 collaboration
Leonid Padyukov 1 collaboration
Anna-Maria Hoffmann-Vold 1 collaboration
Benedicte Lie 1 collaboration
Susanna Proudman 1 collaboration
Wendy Stevens 1 collaboration
Timothy Vyse 1 collaboration
Ariane L Herrick 1 collaboration
Jane Worthington 1 collaboration
Matthew A Brown 1 collaboration
José L Callejas 1 collaboration
International SSc Group 1 collaboration
Australian Scleroderma Interest Group Asig 1 collaboration
Susanna M Proudman 1 collaboration
Xia Jiang 1 collaboration
Blas Chaves-Urbano 1 collaboration
Arancha Poo-López 1 collaboration
Luis Fernández-Vega-Cueto 1 collaboration
Jesús Merayo-Lloves 1 collaboration
Ignacio Alcalde 1 collaboration
Alsya J Affandi 1 collaboration
Tiago Carvalheiro 1 collaboration
Andrea Ottria 1 collaboration
Jasper Ca Broen 1 collaboration
Ralph G Tieland 1 collaboration
Lenny van Bon 1 collaboration
Eleni Chouri 1 collaboration
Marzia Rossato 1 collaboration
Jorre S Mertens 1 collaboration
Samuel Garcia 1 collaboration
Aridaman Pandit 1 collaboration
Laurie Mg de Kroon 1 collaboration
Romy B Christmann 1 collaboration
Joel Ag van Roon 1 collaboration
Wioleta Marut 1 collaboration
José Antonio Castilla 1 collaboration
Andrea Guzmán-Jimenez 1 collaboration
Inmaculada Rodríguez-Martín 1 collaboration
Elio G Carmona 1 collaboration
Jose Luis Callejas-Rubio 1 collaboration
Norbert Mages 1 collaboration
Sven Klages 1 collaboration
Stefan Börno 1 collaboration
Bernd Timmermann 1 collaboration