M Allegretti

Affiliations

Dompé farmaceutici SpA, Via Campo di Pile, 67100 L'Aquila, Italy. Electronic address: marcello.allegretti@dompe.com.

Publications (28)

Emerging Role of C5 Complement Pathway in Peripheral Neuropathies: Current Treatments and Future Perspectives.

Biomedicines

Avec: Cristina Giorgio , Mara Zippoli , Pasquale Cocchiaro , Vanessa Castelli , Giustino Varrassi , Andrea Aramini , Marcello Allegretti , Laura Brandolini , Maria Candida Cesta

Endogenous modification of the chemoattractant CXCL5 alters receptor usage and enhances its activity toward neutrophils and monocytes.

Science signaling

Avec: Mieke Metzemaekers , Anneleen Mortier , Alessandro Vacchini , Daiane Boff , Karen Yu , Rik Janssens , Floriana M Farina , Samantha Milanesi , Nele Berghmans , Noëmie Pörtner , Jo Van Damme , Marcello Allegretti , Mauro M Teixeira , Massimo Locati , Elena M Borroni , Flavio A Amaral , Paul Proost

[Corrigendum] TOOLBOX: Strep‑Tagged nano‑assemblies of antibody‑drug‑conjugates (ADC) for modular and conditional cancer drugging.

Oncology reports

Avec: Elisa Tremante , Leonardo Sibilio , Fabio Centola , Nadine Knutti , Gerd Holzapfel , Isabella Manni , Matteo Allegretti , Paolo Lombardi , Giuseppe Salvo , Loredana Cecchetelli , Karlheinz Friedrich , Joachim Bertram , Patrizio Giacomini

Intravitreal Administration of rhNGF Enhances Regenerative Processes in a Zebrafish Model of Retinal Degeneration.

Frontiers in pharmacology

Avec: Pasquale Cocchiaro , Vincenzo Di Donato , Davide Rubbini , Rodolfo Mastropasqua , Marcello Allegretti , Flavio Mantelli , Andrea Aramini , Laura Brandolini

MicroRNAs Expression in Response to rhNGF in Epithelial Corneal Cells: Focus on Neurotrophin Signaling Pathway.

International journal of molecular sciences

Avec: Chiara Compagnoni , Veronica Zelli , Andrea Bianchi , Antinisca Di Marco , Roberta Capelli , Davide Vecchiotti , Laura Brandolini , Anna Maria Cimini , Francesca Zazzeroni , Marcello Allegretti , Edoardo Alesse , Alessandra Tessitore

Ketoprofen lysine salt has a better gastrointestinal and renal tolerability than ketoprofen acid: A comparative tolerability study in the Beagle dog.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: Rubina Novelli , Andrea Aramini , Serena Boccella , Michela Bagnasco , Franca Cattani , Mauro Paolo Ferrari , Giovanni Goisis , Enrico Maria Minnella , Marcello Allegretti , Virgilio Pace

Clinical Efficacy of Carbocysteine in COPD: Beyond the Mucolytic Action.

Pharmaceutics

Avec: Elisabetta Pace , Isa Cerveri , Donato Lacedonia , Gregorino Paone , Alessandro Sanduzzi Zamparelli , Rossella Sorbo , Marcello Allegretti , Luigi Lanata , Francesco Scaglione

Fatigue in patients with metastatic breast cancer undergoing single-agent taxane-based chemotherapy: a real-world data global network.

Therapeutic advances in medical oncology

Avec: Alessandra Fabi , Elizabeth M Gavioli , Renuka Wakade , Maria C Spera , Santiago Miracle , Neus Valveny , Elizabeth Butler , Maria DePizzol , Pier Adelchi Ruffini , Marcello Allegretti

Tumor-secreted extracellular vesicles counteract therapy response by triggering inflammatory mesenchymal stem cell development.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Crescenzo Massaro , Hilal N Sensoy , Manon Mulders , Celine De Schrijver , Cristina Gomez-Martin , Juan Simon-Nieto , Tonny Lagerweij , Alisha Atmopawiro , Jennifer Perez-Boza , Maarten Bebelman , Leontien Bosch , Simone Foderaro , Mafalda Neves Ferreira , Monique A J van Eijndhoven , Jan R T van Weering , Carmela Dell'Aversana , Lucia Altucci , C Dilara Savci-Heijink , Niels W C J van de Donk , Cristina Giorgio , Laura Brandolini , Marcello Allegretti , D Michiel Pegtel , S Rubina Baglio

Emerging Approaches for the Management of Chemotherapy-Induced Peripheral Neuropathy (CIPN): Therapeutic Potential of the C5a/C5aR Axis.

Pain and therapy

Avec: Maria C Spera , Maria C Cesta , Mara Zippoli , Giustino Varrassi , Marcello Allegretti

Neutrophil activation and neutrophil extracellular traps (NETs) in COVID-19 ARDS and immunothrombosis.

European journal of immunology

Avec: Maria Candida Cesta , Mara Zippoli , Carolina Marsiglia , Elizabeth M Gavioli , Giada Cremonesi , Akram Khan , Flavio Mantelli , Marcello Allegretti , Robert Balk

Differential Effects of Nonsteroidal Anti-Inflammatory Drugs in an In Vitro Model of Human Leaky Gut.

Cells

Avec: Michele d'Angelo , Laura Brandolini , Mariano Catanesi , Vanessa Castelli , Cristina Giorgio , Margherita Alfonsetti , Mara Tomassetti , Mara Zippoli , Elisabetta Benedetti , Maria Candida Cesta , Sandro Colagioia , Pasquale Cocchiaro , Annamaria Cimini , Marcello Allegretti

Inhibition of C5aR1 as a promising approach to treat taxane-induced neuropathy.

Cytokine

Avec: C Cristiano , C Giorgio , P Cocchiaro , S Boccella , M C Cesta , V Castelli , F M Liguori , M R Cuozzo , L Brandolini , R Russo , M Allegretti

Immunosignatures associated with TP53 status and co-mutations classify prognostically head and neck cancer patients.

Molecular cancer

Avec: Andrea Sacconi , Paola Muti , Claudio Pulito , Giulia Urbani , Matteo Allegretti , Raul Pellini , Nikolay Mehterov , Uri Ben-David , Sabrina Strano , Paolo Bossi , Giovanni Blandino

Intranasal administration of recombinant human BDNF as a potential therapy for some primary headaches.

The journal of headache and pain

Avec: Rosaria Greco , Miriam Francavilla , Sara Facchetti , Chiara Demartini , Anna Maria Zanaboni , Maria Irene Antonangeli , Mariano Maffei , Franca Cattani , Andrea Aramini , Marcello Allegretti , Cristina Tassorelli , Lidia De Filippis

Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.

Nature structural & molecular biology

Avec: Byung-Gil Lee , Fabian Merkel , Matteo Allegretti , Markus Hassler , Christopher Cawood , Léa Lecomte , Francis J O'Reilly , Ludwig R Sinn , Pilar Gutierrez-Escribano , Marc Kschonsak , Sol Bravo , Takanori Nakane , Juri Rappsilber , Luis Aragon , Martin Beck , Jan Löwe , Christian H Haering

Effect of recombinant human nerve growth factor eye drops in patients with dry eye: a phase IIa, open label, multiple-dose study.

The British journal of ophthalmology

Avec: Marta Sacchetti , Alessandro Lambiase , Doreen Schmidl , Leopold Schmetterer , Mauro Ferrari , Flavio Mantelli , Marcello Allegretti , Gerhard Garhoefer

Topical Recombinant Human Nerve Growth Factor (Cenegermin) for Neurotrophic Keratopathy: A Multicenter Randomized Vehicle-Controlled Pivotal Trial.

Ophthalmology

Avec: Stephen C Pflugfelder , Mina Massaro-Giordano , Victor L Perez , Pedram Hamrah , Sophie X Deng , Ladan Espandar , C Stephen Foster , John Affeldt , John A Seedor , Natalie A Afshari , Wendy Chao , Marcello Allegretti , Flavio Mantelli , Reza Dana

Chemokine Signaling in Chemotherapy-Induced Neuropathic Pain.

International journal of molecular sciences

Avec: Laura Brandolini , Michele d'Angelo , Andrea Antonosante , Marcello Allegretti , Annamaria Cimini

Looking for In Vitro Models for Retinal Diseases.

International journal of molecular sciences

Avec: Margherita Alfonsetti , Vanessa Castelli , Michele d'Angelo , Elisabetta Benedetti , Marcello Allegretti , Barbara Barboni , Annamaria Cimini

Characterization of raloxifene as a potential pharmacological agent against SARS-CoV-2 and its variants.

Cell death & disease

Avec: Daniela Iaconis , Licia Bordi , Giulia Matusali , Carmine Talarico , Candida Manelfi , Maria Candida Cesta , Mara Zippoli , Francesca Caccuri , Antonella Bugatti , Alberto Zani , Federica Filippini , Laura Scorzolini , Marco Gobbi , Marten Beeg , Arianna Piotti , Monica Montopoli , Veronica Cocetta , Silvia Bressan , Enrico M Bucci , Arnaldo Caruso , Emanuele Nicastri , Marcello Allegretti , Andrea R Beccari

CXCL1-CXCR1/2 signaling is induced in human temporal lobe epilepsy and contributes to seizures in a murine model of acquired epilepsy.

Neurobiology of disease

Avec: Rossella Di Sapia , Till S Zimmer , Valentina Kebede , Silvia Balosso , Teresa Ravizza , Diletta Sorrentino , Manuel Alejandro Montano Castillo , Luca Porcu , Franca Cattani , Anna Ruocco , Eleonora Aronica , Marcello Allegretti , Laura Brandolini , Annamaria Vezzani

Repurposing the estrogen receptor modulator raloxifene to treat SARS-CoV-2 infection.

Cell death and differentiation

Avec: Marcello Allegretti , Maria Candida Cesta , Mara Zippoli , Andrea Beccari , Carmine Talarico , Flavio Mantelli , Enrico M Bucci , Laura Scorzolini , Emanuele Nicastri

L-Methionine Protects against Oxidative Stress and Mitochondrial Dysfunction in an In Vitro Model of Parkinson's Disease.

Antioxidants (Basel, Switzerland)

Avec: Mariano Catanesi , Laura Brandolini , Michele d'Angelo , Elisabetta Benedetti , Maria Grazia Tupone , Margherita Alfonsetti , Enrico Cabri , Daniela Iaconis , Maddalena Fratelli , Annamaria Cimini , Vanessa Castelli , Marcello Allegretti

CXCR1/2 Inhibitor Ladarixin Ameliorates the Insulin Resistance of 3T3-L1 Adipocytes by Inhibiting Inflammation and Improving Insulin Signaling.

Cells

Avec: Vanessa Castelli , Laura Brandolini , Michele d'Angelo , Cristina Giorgio , Margherita Alfonsetti , Pasquale Cocchiaro , Francesca Lombardi , Annamaria Cimini , Marcello Allegretti

ProNGF processing in adult rat tissues and bioactivity of NGF prodomain peptides.

FEBS open bio

Avec: Marie Anne Makoudjou , Elena Fico , Pamela Rosso , Viviana Triaca , Lucio De Simone , Daniela Rossetti , Franca Cattani , Marcello Allegretti , Paola Tirassa

DHFR Inhibitors Display a Pleiotropic Anti-Viral Activity against SARS-CoV-2: Insights into the Mechanisms of Action.

Viruses

Avec: Daniela Iaconis , Francesca Caccuri , Candida Manelfi , Carmine Talarico , Antonella Bugatti , Federica Filippini , Alberto Zani , Rubina Novelli , Maria Kuzikov , Bernhard Ellinger , Philip Gribbon , Kristoffer Riecken , Francesca Esposito , Angela Corona , Enzo Tramontano , Andrea Rosario Beccari , Arnaldo Caruso , Marcello Allegretti

C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps.

The Journal of clinical investigation

Avec: Bruna M Silva , Giovanni F Gomes , Flavio P Veras , Seppe Cambier , Gabriel Vl Silva , Andreza U Quadros , Diego B Caetité , Daniele C Nascimento , Camilla M Silva , Juliana C Silva , Samara Damasceno , Ayda H Schneider , Fabio Beretta , Sabrina S Batah , Icaro Ms Castro , Isadora M Paiva , Tamara Rodrigues , Ana Salina , Ronaldo Martins , Guilherme Cm Cebinelli , Naira L Bibo , Daniel M Jorge , Helder I Nakaya , Dario S Zamboni , Luiz O Leiria , Alexandre T Fabro , José C Alves-Filho , Eurico Arruda , Paulo Louzada-Junior , Renê D Oliveira , Larissa D Cunha , Pierre Van Mol , Lore Vanderbeke , Simon Feys , Els Wauters , Laura Brandolini , Andrea Aramini , Fernando Q Cunha , Jörg Köhl , Marcello Allegretti , Diether Lambrechts , Joost Wauters , Paul Proost , Thiago M Cunha

Réseau de co-auteurs

Marcello Allegretti 24 collaborations

Laura Brandolini 10 collaborations

Mara Zippoli 6 collaborations

Vanessa Castelli 5 collaborations

Andrea Aramini 5 collaborations

Maria Candida Cesta 5 collaborations

Flavio Mantelli 5 collaborations

Michele d'Angelo 5 collaborations

Annamaria Cimini 5 collaborations

Cristina Giorgio 4 collaborations

Pasquale Cocchiaro 4 collaborations

Franca Cattani 4 collaborations

Margherita Alfonsetti 4 collaborations

Matteo Allegretti 3 collaborations

Elisabetta Benedetti 3 collaborations

Daniela Iaconis 3 collaborations

Carmine Talarico 3 collaborations

Giustino Varrassi 2 collaborations

Paul Proost 2 collaborations

Rubina Novelli 2 collaborations

Elizabeth M Gavioli 2 collaborations

Maria C Spera 2 collaborations

Mariano Catanesi 2 collaborations

Candida Manelfi 2 collaborations

Francesca Caccuri 2 collaborations

Antonella Bugatti 2 collaborations

Alberto Zani 2 collaborations

Federica Filippini 2 collaborations

Laura Scorzolini 2 collaborations

Enrico M Bucci 2 collaborations

Arnaldo Caruso 2 collaborations

Emanuele Nicastri 2 collaborations

Mieke Metzemaekers 1 collaboration

Anneleen Mortier 1 collaboration

Alessandro Vacchini 1 collaboration

Daiane Boff 1 collaboration

Karen Yu 1 collaboration

Rik Janssens 1 collaboration

Floriana M Farina 1 collaboration

Samantha Milanesi 1 collaboration

Nele Berghmans 1 collaboration

Noëmie Pörtner 1 collaboration

Jo Van Damme 1 collaboration

Mauro M Teixeira 1 collaboration

Massimo Locati 1 collaboration

Elena M Borroni 1 collaboration

Flavio A Amaral 1 collaboration

Elisa Tremante 1 collaboration

Leonardo Sibilio 1 collaboration

Fabio Centola 1 collaboration

Nadine Knutti 1 collaboration

Gerd Holzapfel 1 collaboration

Isabella Manni 1 collaboration

Paolo Lombardi 1 collaboration

Giuseppe Salvo 1 collaboration

Loredana Cecchetelli 1 collaboration

Karlheinz Friedrich 1 collaboration

Joachim Bertram 1 collaboration

Patrizio Giacomini 1 collaboration

Vincenzo Di Donato 1 collaboration

Davide Rubbini 1 collaboration

Rodolfo Mastropasqua 1 collaboration

Chiara Compagnoni 1 collaboration

Veronica Zelli 1 collaboration

Andrea Bianchi 1 collaboration

Antinisca Di Marco 1 collaboration

Roberta Capelli 1 collaboration

Davide Vecchiotti 1 collaboration

Anna Maria Cimini 1 collaboration

Francesca Zazzeroni 1 collaboration

Edoardo Alesse 1 collaboration

Alessandra Tessitore 1 collaboration

Serena Boccella 1 collaboration

Michela Bagnasco 1 collaboration

Mauro Paolo Ferrari 1 collaboration

Giovanni Goisis 1 collaboration

Enrico Maria Minnella 1 collaboration

Virgilio Pace 1 collaboration

Elisabetta Pace 1 collaboration

Isa Cerveri 1 collaboration

Donato Lacedonia 1 collaboration

Gregorino Paone 1 collaboration

Alessandro Sanduzzi Zamparelli 1 collaboration

Rossella Sorbo 1 collaboration

Luigi Lanata 1 collaboration

Francesco Scaglione 1 collaboration

Alessandra Fabi 1 collaboration

Renuka Wakade 1 collaboration

Santiago Miracle 1 collaboration

Neus Valveny 1 collaboration

Elizabeth Butler 1 collaboration

Maria DePizzol 1 collaboration

Pier Adelchi Ruffini 1 collaboration

Crescenzo Massaro 1 collaboration

Hilal N Sensoy 1 collaboration

Manon Mulders 1 collaboration

Celine De Schrijver 1 collaboration

Cristina Gomez-Martin 1 collaboration

Juan Simon-Nieto 1 collaboration

Tonny Lagerweij 1 collaboration

Alisha Atmopawiro 1 collaboration

Jennifer Perez-Boza 1 collaboration

Maarten Bebelman 1 collaboration

Leontien Bosch 1 collaboration

Simone Foderaro 1 collaboration

Mafalda Neves Ferreira 1 collaboration

Monique A J van Eijndhoven 1 collaboration

Jan R T van Weering 1 collaboration

Carmela Dell'Aversana 1 collaboration

Lucia Altucci 1 collaboration

C Dilara Savci-Heijink 1 collaboration

Niels W C J van de Donk 1 collaboration

D Michiel Pegtel 1 collaboration

S Rubina Baglio 1 collaboration

Maria C Cesta 1 collaboration

Carolina Marsiglia 1 collaboration

Giada Cremonesi 1 collaboration

Akram Khan 1 collaboration

Robert Balk 1 collaboration

Mara Tomassetti 1 collaboration

Sandro Colagioia 1 collaboration

C Cristiano 1 collaboration

C Giorgio 1 collaboration

P Cocchiaro 1 collaboration

S Boccella 1 collaboration

M C Cesta 1 collaboration

V Castelli 1 collaboration

F M Liguori 1 collaboration

M R Cuozzo 1 collaboration

L Brandolini 1 collaboration

R Russo 1 collaboration

Andrea Sacconi 1 collaboration

Paola Muti 1 collaboration

Claudio Pulito 1 collaboration

Giulia Urbani 1 collaboration

Raul Pellini 1 collaboration

Nikolay Mehterov 1 collaboration

Uri Ben-David 1 collaboration

Sabrina Strano 1 collaboration

Paolo Bossi 1 collaboration

Giovanni Blandino 1 collaboration

Rosaria Greco 1 collaboration

Miriam Francavilla 1 collaboration

Sara Facchetti 1 collaboration

Chiara Demartini 1 collaboration

Anna Maria Zanaboni 1 collaboration

Maria Irene Antonangeli 1 collaboration

Mariano Maffei 1 collaboration

Cristina Tassorelli 1 collaboration

Lidia De Filippis 1 collaboration

Byung-Gil Lee 1 collaboration

Fabian Merkel 1 collaboration

Markus Hassler 1 collaboration

Christopher Cawood 1 collaboration

Léa Lecomte 1 collaboration

Francis J O'Reilly 1 collaboration

Ludwig R Sinn 1 collaboration

Pilar Gutierrez-Escribano 1 collaboration

Marc Kschonsak 1 collaboration

Sol Bravo 1 collaboration

Takanori Nakane 1 collaboration

Juri Rappsilber 1 collaboration

Luis Aragon 1 collaboration

Martin Beck 1 collaboration

Jan Löwe 1 collaboration

Christian H Haering 1 collaboration

Marta Sacchetti 1 collaboration

Alessandro Lambiase 1 collaboration

Doreen Schmidl 1 collaboration

Leopold Schmetterer 1 collaboration

Mauro Ferrari 1 collaboration

Gerhard Garhoefer 1 collaboration

Stephen C Pflugfelder 1 collaboration

Mina Massaro-Giordano 1 collaboration

Victor L Perez 1 collaboration

Pedram Hamrah 1 collaboration

Sophie X Deng 1 collaboration

Ladan Espandar 1 collaboration

C Stephen Foster 1 collaboration

John Affeldt 1 collaboration

John A Seedor 1 collaboration

Natalie A Afshari 1 collaboration

Wendy Chao 1 collaboration

Reza Dana 1 collaboration

Andrea Antonosante 1 collaboration

Barbara Barboni 1 collaboration

Licia Bordi 1 collaboration

Giulia Matusali 1 collaboration

Marco Gobbi 1 collaboration

Marten Beeg 1 collaboration

Arianna Piotti 1 collaboration

Monica Montopoli 1 collaboration

Veronica Cocetta 1 collaboration

Silvia Bressan 1 collaboration

Andrea R Beccari 1 collaboration

Rossella Di Sapia 1 collaboration

Till S Zimmer 1 collaboration

Valentina Kebede 1 collaboration

Silvia Balosso 1 collaboration

Teresa Ravizza 1 collaboration

Diletta Sorrentino 1 collaboration

Manuel Alejandro Montano Castillo 1 collaboration

Luca Porcu 1 collaboration

Anna Ruocco 1 collaboration

Eleonora Aronica 1 collaboration

Annamaria Vezzani 1 collaboration

Andrea Beccari 1 collaboration

Maria Grazia Tupone 1 collaboration

Enrico Cabri 1 collaboration

Maddalena Fratelli 1 collaboration

Francesca Lombardi 1 collaboration

Marie Anne Makoudjou 1 collaboration

Elena Fico 1 collaboration

Pamela Rosso 1 collaboration

Viviana Triaca 1 collaboration

Lucio De Simone 1 collaboration

Daniela Rossetti 1 collaboration

Paola Tirassa 1 collaboration

Maria Kuzikov 1 collaboration

Bernhard Ellinger 1 collaboration

Philip Gribbon 1 collaboration

Kristoffer Riecken 1 collaboration

Francesca Esposito 1 collaboration

Angela Corona 1 collaboration

Enzo Tramontano 1 collaboration

Andrea Rosario Beccari 1 collaboration

Bruna M Silva 1 collaboration

Giovanni F Gomes 1 collaboration

Flavio P Veras 1 collaboration

Seppe Cambier 1 collaboration

Gabriel Vl Silva 1 collaboration

Andreza U Quadros 1 collaboration

Diego B Caetité 1 collaboration

Daniele C Nascimento 1 collaboration

Camilla M Silva 1 collaboration

Juliana C Silva 1 collaboration

Samara Damasceno 1 collaboration

Ayda H Schneider 1 collaboration

Fabio Beretta 1 collaboration

Sabrina S Batah 1 collaboration

Icaro Ms Castro 1 collaboration

Isadora M Paiva 1 collaboration

Tamara Rodrigues 1 collaboration

Ana Salina 1 collaboration

Ronaldo Martins 1 collaboration

Guilherme Cm Cebinelli 1 collaboration

Naira L Bibo 1 collaboration

Daniel M Jorge 1 collaboration

Helder I Nakaya 1 collaboration

Dario S Zamboni 1 collaboration

Luiz O Leiria 1 collaboration

Alexandre T Fabro 1 collaboration

José C Alves-Filho 1 collaboration

Eurico Arruda 1 collaboration

Paulo Louzada-Junior 1 collaboration

Renê D Oliveira 1 collaboration

Larissa D Cunha 1 collaboration

Pierre Van Mol 1 collaboration

Lore Vanderbeke 1 collaboration

Simon Feys 1 collaboration

Els Wauters 1 collaboration

Fernando Q Cunha 1 collaboration

Jörg Köhl 1 collaboration

Diether Lambrechts 1 collaboration

Joost Wauters 1 collaboration

Thiago M Cunha 1 collaboration