M Morari

Affiliations

Department of Medical Sciences, Section of Pharmacology, University of Ferrara, via Fossato di Mortara 17-19, 44121 Ferrara, Italy.
Neuroscience Center and National Institute of Neuroscience, University of Ferrara, via Fossato di Mortara 17-19, 44121 Ferrara, Italy.

Publications (25)

Early Dysfunction of Substantia Nigra Dopamine Neurons in the ParkinQ311X Mouse.

Biomedicines

Avec: Maria Regoni , Letizia Zanetti , Stefano Comai , Daniela Mercatelli , Salvatore Novello , Federica Albanese , Laura Croci , Gian Giacomo Consalez , Andrea Ciammola , Flavia Valtorta , Michele Morari , Jenny Sassone

NOP Receptor Ligands and Parkinson's Disease.

Handbook of experimental pharmacology

Avec: Daniela Mercatelli , Clarissa Anna Pisanò , Salvatore Novello , Michele Morari

l-DOPA promotes striatal dopamine release through D1 receptors and reversal of dopamine transporter.

Brain research

Avec: Riccardo Viaro , Francesco Longo , Fabrizio Vincenzi , Katia Varani , Michele Morari

Mitochondrial P2X7 Receptor Localization Modulates Energy Metabolism Enhancing Physical Performance.

Function (Oxford, England)

Avec: Alba Clara Sarti , Valentina Vultaggio-Poma , Simonetta Falzoni , Sonia Missiroli , Anna Lisa Giuliani , Paola Boldrini , Massimo Bonora , Francesco Faita , Nicole Di Lascio , Claudia Kusmic , Anna Solini , Salvatore Novello , Michele Morari , Marco Rossato , Mariusz R Wieckowski , Carlotta Giorgi , Paolo Pinton , Francesco Di Virgilio

Modeling Parkinson's disease in LRRK2 rodents.

Neuronal signaling

Avec: Chiara Domenicale , Stefano Magnabosco , Michele Morari

Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates.

Science advances

Avec: M Bourdenx , A Nioche , S Dovero , M-L Arotcarena , S Camus , G Porras , M-L Thiolat , N P Rougier , A Prigent , P Aubert , S Bohic , C Sandt , F Laferrière , E Doudnikoff , N Kruse , B Mollenhauer , S Novello , M Morari , T Leste-Lasserre , I Trigo Damas , M Goillandeau , C Perier , C Estrada , N Garcia-Carrillo , A Recasens , N N Vaikath , O M A El-Agnaf , M T Herrero , P Derkinderen , M Vila , J A Obeso , B Dehay , E Bezard

6-Hydroxydopamine lesion and levodopa treatment modify the effect of buspirone in the substantia nigra pars reticulata.

British journal of pharmacology

Avec: Sergio Vegas-Suárez , Clarissa Anna Pisanò , Catalina Requejo , Harkaitz Bengoetxea , Jose Vicente Lafuente , Michele Morari , Cristina Miguelez , Luisa Ugedo

Gene Co-expression Analysis Identifies Histone Deacetylase 5 and 9 Expression in Midbrain Dopamine Neurons and as Regulators of Neurite Growth via Bone Morphogenetic Protein Signaling.

Frontiers in cell and developmental biology

Avec: Martina Mazzocchi , Sean L Wyatt , Daniela Mercatelli , Michele Morari , Noelia Morales-Prieto , Louise M Collins , Aideen M Sullivan , Gerard W O'Keeffe

Safinamide inhibits in vivo glutamate release in a rat model of Parkinson's disease.

Neuropharmacology

Avec: Clarissa A Pisanò , Alberto Brugnoli , Salvatore Novello , Carla Caccia , Charlotte Keywood , Elsa Melloni , Silvia Vailati , Gloria Padoani , Michele Morari

Modeling Parkinson's disease in LRRK2 mice: focus on synaptic dysfunction and the autophagy-lysosomal pathway.

Biochemical Society transactions

Avec: Federica Albanese , Chiara Domenicale , Mattia Volta , Michele Morari

Regulator of G-Protein Signalling 4 (RGS4) negatively modulates nociceptin/orphanin FQ opioid receptor signalling: Implication for l-Dopa-induced dyskinesia.

British journal of pharmacology

Avec: Clarissa A Pisanò , Daniela Mercatelli , Martina Mazzocchi , Alberto Brugnoli , Ilaria Morella , Stefania Fasano , Nurulain T Zaveri , Riccardo Brambilla , Gerard W O'Keeffe , Richard R Neubig , Michele Morari

LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation.

Brain : a journal of neurology

Avec: Francesca Pischedda , Maria Daniela Cirnaru , Luisa Ponzoni , Michele Sandre , Alice Biosa , Maria Perez Carrion , Oriano Marin , Michele Morari , Lifeng Pan , Elisa Greggio , Rina Bandopadhyay , Mariaelvina Sala , Giovanni Piccoli

Dopamine Transporter, PhosphoSerine129 α-Synuclein and α-Synuclein Levels in Aged LRRK2 G2019S Knock-In and Knock-Out Mice.

Biomedicines

Avec: Chiara Domenicale , Daniela Mercatelli , Federica Albanese , Salvatore Novello , Fabrizio Vincenzi , Katia Varani , Michele Morari

Development of a new toolbox for mouse PET-CT brain image analysis fully based on CT images and validation in a PD mouse model.

Scientific reports

Avec: L Presotto , V Bettinardi , D Mercatelli , M Picchio , M Morari , R M Moresco , Sara Belloli

Leucine-rich repeat kinase 2 (LRRK2) inhibitors differentially modulate glutamate release and Serine935 LRRK2 phosphorylation in striatal and cerebrocortical synaptosomes.

Pharmacology research & perspectives

Avec: Daniela Mercatelli , Paolo Bolognesi , Martina Frassineti , Clarissa A Pisanò , Francesco Longo , Derya R Shimshek , Michele Morari

Autophagy and LRRK2 in the Aging Brain.

Frontiers in neuroscience

Avec: Federica Albanese , Salvatore Novello , Michele Morari

In vivo susceptibility to energy failure parkinsonism and LRRK2 kinase activity.

Neurobiology of disease

Avec: Salvatore Novello , Daniela Mercatelli , Federica Albanese , Chiara Domenicale , Alberto Brugnoli , Elisabetta D'Aversa , Silvia Vantaggiato , Sandra Dovero , Valentina Murtaj , Luca Presotto , Monica Borgatti , Derya R Shimshek , Erwan Bezard , Rosa Maria Moresco , Sara Belloli , Michele Morari

Dopamine neuron dysfunction and loss in the PrknR275W mouse model of juvenile parkinsonism.

Brain : a journal of neurology

Avec: Maria Regoni , Letizia Zanetti , Martina Sevegnani , Chiara Domenicale , Stefano Magnabosco , Jyoti C Patel , Megan K Fernandes , Ryan M Feeley , Elena Monzani , Cecilia Mini , Stefano Comai , Laura Cherchi , Danilo De Gregorio , Isabella Soliman , Fabio Ruto , Laura Croci , Giacomo Consalez , Simona Rodighiero , Andrea Ciammola , Flavia Valtorta , Michele Morari , Giovanni Piccoli , Margaret E Rice , Jenny Sassone

Translation Imaging in Parkinson's Disease: Focus on Neuroinflammation.

Frontiers in aging neuroscience

Avec: Sara Belloli , Michele Morari , Valentina Murtaj , Silvia Valtorta , Rosa Maria Moresco , Maria Carla Gilardi

Striatal and nigral muscarinic type 1 and type 4 receptors modulate levodopa-induced dyskinesia and striato-nigral pathway activation in 6-hydroxydopamine hemilesioned rats.

Neurobiology of disease

Avec: Alberto Brugnoli , Clarissa Anna Pisanò , Michele Morari

Discovery and Structure-Activity Relationships of Nociceptin Receptor Partial Agonists That Afford Symptom Ablation in Parkinson's Disease Models.

Journal of medicinal chemistry

Avec: Uma Gayathri Kamakolanu , Michael E Meyer , Dennis Yasuda , Willma E Polgar , Matteo Marti , Daniela Mercatelli , Clarissa Anna Pisanò , Alberto Brugnoli , Michele Morari , Nurulain T Zaveri

Managing Parkinson's disease: moving ON with NOP.

British journal of pharmacology

Avec: Daniela Mercatelli , Erwan Bezard , Roberto Eleopra , Nurulain T Zaveri , Michele Morari

Pharmacological antagonism of kainate receptor rescues dysfunction and loss of dopamine neurons in a mouse model of human parkin-induced toxicity.

Cell death & disease

Avec: Maria Regoni , Stefano Cattaneo , Daniela Mercatelli , Salvatore Novello , Alice Passoni , Renzo Bagnati , Enrico Davoli , Laura Croci , Gian Giacomo Consalez , Federica Albanese , Letizia Zanetti , Maria Passafaro , Giulia Maia Serratto , Alessio Di Fonzo , Flavia Valtorta , Andrea Ciammola , Stefano Taverna , Michele Morari , Jenny Sassone

Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo.

Neurobiology of disease

Avec: Federica Albanese , Daniela Mercatelli , Luca Finetti , Giulia Lamonaca , Sara Pizzi , Derya R Shimshek , Giovanni Bernacchia , Michele Morari

Brain injections of glial cytoplasmic inclusions induce a multiple system atrophy-like pathology.

Brain : a journal of neurology

Avec: Margaux Teil , Sandra Dovero , Mathieu Bourdenx , Marie-Laure Arotcarena , Sandrine Camus , Gregory Porras , Marie-Laure Thiolat , Ines Trigo-Damas , Celine Perier , Cristina Estrada , Nuria Garcia-Carrillo , Michele Morari , Wassilios G Meissner , María Trinidad Herrero , Miquel Vila , Jose A Obeso , Erwan Bezard , Benjamin Dehay

Réseau de co-auteurs

Michele Morari 23 collaborations

Daniela Mercatelli 11 collaborations

Salvatore Novello 8 collaborations

Federica Albanese 7 collaborations

Chiara Domenicale 5 collaborations

Alberto Brugnoli 5 collaborations

Clarissa Anna Pisanò 4 collaborations

Maria Regoni 3 collaborations

Letizia Zanetti 3 collaborations

Laura Croci 3 collaborations

Andrea Ciammola 3 collaborations

Flavia Valtorta 3 collaborations

Jenny Sassone 3 collaborations

Clarissa A Pisanò 3 collaborations

Nurulain T Zaveri 3 collaborations

Sara Belloli 3 collaborations

Derya R Shimshek 3 collaborations

Erwan Bezard 3 collaborations

Stefano Comai 2 collaborations

Gian Giacomo Consalez 2 collaborations

Francesco Longo 2 collaborations

Fabrizio Vincenzi 2 collaborations

Katia Varani 2 collaborations

Stefano Magnabosco 2 collaborations

Martina Mazzocchi 2 collaborations

Gerard W O'Keeffe 2 collaborations

Giovanni Piccoli 2 collaborations

Sandra Dovero 2 collaborations

Valentina Murtaj 2 collaborations

Rosa Maria Moresco 2 collaborations

Riccardo Viaro 1 collaboration

Alba Clara Sarti 1 collaboration

Valentina Vultaggio-Poma 1 collaboration

Simonetta Falzoni 1 collaboration

Sonia Missiroli 1 collaboration

Anna Lisa Giuliani 1 collaboration

Paola Boldrini 1 collaboration

Massimo Bonora 1 collaboration

Francesco Faita 1 collaboration

Nicole Di Lascio 1 collaboration

Claudia Kusmic 1 collaboration

Anna Solini 1 collaboration

Marco Rossato 1 collaboration

Mariusz R Wieckowski 1 collaboration

Carlotta Giorgi 1 collaboration

Paolo Pinton 1 collaboration

Francesco Di Virgilio 1 collaboration

M Bourdenx 1 collaboration

A Nioche 1 collaboration

S Dovero 1 collaboration

M-L Arotcarena 1 collaboration

S Camus 1 collaboration

G Porras 1 collaboration

M-L Thiolat 1 collaboration

N P Rougier 1 collaboration

A Prigent 1 collaboration

P Aubert 1 collaboration

S Bohic 1 collaboration

C Sandt 1 collaboration

F Laferrière 1 collaboration

E Doudnikoff 1 collaboration

N Kruse 1 collaboration

B Mollenhauer 1 collaboration

S Novello 1 collaboration

T Leste-Lasserre 1 collaboration

I Trigo Damas 1 collaboration

M Goillandeau 1 collaboration

C Perier 1 collaboration

C Estrada 1 collaboration

N Garcia-Carrillo 1 collaboration

A Recasens 1 collaboration

N N Vaikath 1 collaboration

O M A El-Agnaf 1 collaboration

M T Herrero 1 collaboration

P Derkinderen 1 collaboration

M Vila 1 collaboration

J A Obeso 1 collaboration

B Dehay 1 collaboration

E Bezard 1 collaboration

Sergio Vegas-Suárez 1 collaboration

Catalina Requejo 1 collaboration

Harkaitz Bengoetxea 1 collaboration

Jose Vicente Lafuente 1 collaboration

Cristina Miguelez 1 collaboration

Luisa Ugedo 1 collaboration

Sean L Wyatt 1 collaboration

Noelia Morales-Prieto 1 collaboration

Louise M Collins 1 collaboration

Aideen M Sullivan 1 collaboration

Carla Caccia 1 collaboration

Charlotte Keywood 1 collaboration

Elsa Melloni 1 collaboration

Silvia Vailati 1 collaboration

Gloria Padoani 1 collaboration

Mattia Volta 1 collaboration

Ilaria Morella 1 collaboration

Stefania Fasano 1 collaboration

Riccardo Brambilla 1 collaboration

Richard R Neubig 1 collaboration

Francesca Pischedda 1 collaboration

Maria Daniela Cirnaru 1 collaboration

Luisa Ponzoni 1 collaboration

Michele Sandre 1 collaboration

Alice Biosa 1 collaboration

Maria Perez Carrion 1 collaboration

Oriano Marin 1 collaboration

Lifeng Pan 1 collaboration

Elisa Greggio 1 collaboration

Rina Bandopadhyay 1 collaboration

Mariaelvina Sala 1 collaboration

L Presotto 1 collaboration

V Bettinardi 1 collaboration

D Mercatelli 1 collaboration

M Picchio 1 collaboration

R M Moresco 1 collaboration

Paolo Bolognesi 1 collaboration

Martina Frassineti 1 collaboration

Elisabetta D'Aversa 1 collaboration

Silvia Vantaggiato 1 collaboration

Luca Presotto 1 collaboration

Monica Borgatti 1 collaboration

Martina Sevegnani 1 collaboration

Jyoti C Patel 1 collaboration

Megan K Fernandes 1 collaboration

Ryan M Feeley 1 collaboration

Elena Monzani 1 collaboration

Cecilia Mini 1 collaboration

Laura Cherchi 1 collaboration

Danilo De Gregorio 1 collaboration

Isabella Soliman 1 collaboration

Fabio Ruto 1 collaboration

Giacomo Consalez 1 collaboration

Simona Rodighiero 1 collaboration

Margaret E Rice 1 collaboration

Silvia Valtorta 1 collaboration

Maria Carla Gilardi 1 collaboration

Uma Gayathri Kamakolanu 1 collaboration

Michael E Meyer 1 collaboration

Dennis Yasuda 1 collaboration

Willma E Polgar 1 collaboration

Matteo Marti 1 collaboration

Roberto Eleopra 1 collaboration

Stefano Cattaneo 1 collaboration

Alice Passoni 1 collaboration

Renzo Bagnati 1 collaboration

Enrico Davoli 1 collaboration

Maria Passafaro 1 collaboration

Giulia Maia Serratto 1 collaboration

Alessio Di Fonzo 1 collaboration

Stefano Taverna 1 collaboration

Luca Finetti 1 collaboration

Giulia Lamonaca 1 collaboration

Sara Pizzi 1 collaboration

Giovanni Bernacchia 1 collaboration

Margaux Teil 1 collaboration

Mathieu Bourdenx 1 collaboration

Marie-Laure Arotcarena 1 collaboration

Sandrine Camus 1 collaboration

Gregory Porras 1 collaboration

Marie-Laure Thiolat 1 collaboration

Ines Trigo-Damas 1 collaboration

Celine Perier 1 collaboration

Cristina Estrada 1 collaboration

Nuria Garcia-Carrillo 1 collaboration

Wassilios G Meissner 1 collaboration

María Trinidad Herrero 1 collaboration

Miquel Vila 1 collaboration

Jose A Obeso 1 collaboration

Benjamin Dehay 1 collaboration