Mark Trinder

Affiliations

Centre for Heart Lung Innovation, University of British Columbia, Vancouver, British Columbia, Canada.
Experimental Medicine Program, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

Publications (37)

Association of Monogenic vs Polygenic Hypercholesterolemia With Risk of Atherosclerotic Cardiovascular Disease.

JAMA cardiology

Avec: Mark Trinder , Gordon A Francis , Liam R Brunham

The Interplay Between Titin, Polygenic Risk, and Modifiable Cardiovascular Risk Factors in Atrial Fibrillation.

The Canadian journal of cardiology

Avec: Kate Huang , Mark Trinder , Thomas M Roston , Zachary W Laksman , Liam R Brunham

Distinction of lymphoid and myeloid clonal hematopoiesis.

Nature medicine

Avec: Abhishek Niroula , Aswin Sekar , Mark A Murakami , Mark Trinder , Mridul Agrawal , Waihay J Wong , Alexander G Bick , Md Mesbah Uddin , Christopher J Gibson , Gabriel K Griffin , Michael C Honigberg , Seyedeh M Zekavat , Kaavya Paruchuri , Pradeep Natarajan , Benjamin L Ebert

Patient Perspectives Regarding Genetic Testing for Familial Hypercholesterolemia.

CJC open

Avec: Miles Marchand , Victoria Chen , Mark Trinder , Lubomira Cermakova , Liam R Brunham

Does virtual reality in the preoperative setting for colorectal cancer surgery improve patient understanding? A randomized pilot study.

ANZ journal of surgery

Avec: Talia Shepherd , Matthew Trinder , Mary Theophilus

Increased FH-Risk-Score and Diabetes Are Cardiovascular Risk Equivalents in Heterozygous Familial Hypercholesterolemia.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Martine Paquette , Bertrand Cariou , Sophie Bernard , Robert A Hegele , Antonio Gallo , Jacques Genest , Mark Trinder , Liam R Brunham , Sophie Béliard , Alexis Baass

Immobilization of cadmium and lead by

Gut microbes

Avec: Brendan A Daisley , Marc Monachese , Mark Trinder , Jordan E Bisanz , John A Chmiel , Jeremy P Burton , Gregor Reid

Deep Learning of the Retina Enables Phenome- and Genome-Wide Analyses of the Microvasculature.

Circulation

Avec: Seyedeh Maryam Zekavat , Vineet K Raghu , Mark Trinder , Yixuan Ye , Satoshi Koyama , Michael C Honigberg , Zhi Yu , Akhil Pampana , Sarah Urbut , Sara Haidermota , Declan P O'Regan , Hongyu Zhao , Patrick T Ellinor , Ayellet V Segrè , Tobias Elze , Janey L Wiggs , James Martone , Ron A Adelman , Nazlee Zebardast , Lucian Del Priore , Jay C Wang , Pradeep Natarajan

Polygenic scores for dyslipidemia: the emerging genomic model of plasma lipoprotein trait inheritance.

Current opinion in lipidology

Avec: Mark Trinder , Liam R Brunham

Polygenic prediction of preeclampsia and gestational hypertension.

Nature medicine

Avec: Michael C Honigberg , Buu Truong , Raiyan R Khan , Brenda Xiao , Laxmi Bhatta , Ha My T Vy , Rafael F Guerrero , Art Schuermans , Margaret Sunitha Selvaraj , Aniruddh P Patel , Satoshi Koyama , So Mi Jemma Cho , Shamsudheen Karuthedath Vellarikkal , Mark Trinder , Sarah M Urbut , Kathryn J Gray , Ben M Brumpton , Snehal Patil , Sebastian Zöllner , Mariah C Antopia , Richa Saxena , Girish N Nadkarni , Ron Do , Qi Yan , Itsik Pe'er , Shefali Setia Verma , Rajat M Gupta , David M Haas , Hilary C Martin , David A van Heel , Triin Laisk , Pradeep Natarajan

Genetic Identification of Homozygous Familial Hypercholesterolemia by Long-Read Sequencing Among Patients With Clinically Diagnosed Heterozygous Familial Hypercholesterolemia.

Circulation. Genomic and precision medicine

Avec: Ahsen Chaudhry , Mark Trinder , Kristin Vesely , Lubomira Cermakova , Linda Jackson , Jian Wang , Robert A Hegele , Liam R Brunham

Influence of Polygenic Background on the Clinical Presentation of Familial Hypercholesterolemia.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Mark Trinder , Lubomira Cermakova , Isabelle Ruel , Alexis Baass , Martine Paquette , Jian Wang , Brooke A Kennedy , Robert A Hegele , Jacques Genest , Liam R Brunham

Estimating the Prevalence of Familial Hypercholesterolemia in Acute Coronary Syndrome: A Systematic Review and Meta-analysis.

The Canadian journal of cardiology

Avec: Adam I Kramer , Mark Trinder , Liam R Brunham

Familial Hypercholesterolemia-Risk-Score: A New Score Predicting Cardiovascular Events and Cardiovascular Mortality in Familial Hypercholesterolemia.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Martine Paquette , Sophie Bernard , Bertrand Cariou , Robert A Hegele , Jacques Genest , Mark Trinder , Liam R Brunham , Sophie Béliard , Alexis Baass

The Clinical Genome Resource (ClinGen) Familial Hypercholesterolemia Variant Curation Expert Panel consensus guidelines for LDLR variant classification.

Genetics in medicine : official journal of the American College of Medical Genetics

Avec: Joana R Chora , Michael A Iacocca , Lukáš Tichý , Hannah Wand , C Lisa Kurtz , Heather Zimmermann , Annette Leon , Maggie Williams , Steve E Humphries , Amanda J Hooper , Mark Trinder , Liam R Brunham , Alexandre Costa Pereira , Cinthia E Jannes , Margaret Chen , Jessica Chonis , Jian Wang , Serra Kim , Tami Johnston , Premysl Soucek , Michal Kramarek , Sarah E Leigh , Alain Carrié , Eric J Sijbrands , Robert A Hegele , Tomáš Freiberger , Joshua W Knowles , Mafalda Bourbon , Auteur inconnu

Repeat Measures of Lipoprotein(a) Molar Concentration and Cardiovascular Risk.

Journal of the American College of Cardiology

Avec: Mark Trinder , Kaavya Paruchuri , Sara Haidermota , Rachel Bernardo , Seyedeh Maryam Zekavat , Thomas Gilliland , James Januzzi , Pradeep Natarajan

Concordance of a High Lipoprotein(a) Concentration Among Relatives.

JAMA cardiology

Avec: Laurens F Reeskamp , Tycho R Tromp , Aniruddh P Patel , Shirin Ibrahim , Mark Trinder , Sara Haidermota , G Kees Hovingh , Erik S G Stroes , Pradeep Natarajan , Amit V Khera

Genetic Architecture and Clinical Outcomes of Combined Lipid Disturbances.

Circulation research

Avec: Thomas Gilliland , Jacqueline S Dron , Margaret Sunitha Selvaraj , Mark Trinder , Kaavya Paruchuri , Sarah M Urbut , Sara Haidermota , Rachel Bernardo , Md Mesbah Uddin , Michael C Honigberg , Gina M Peloso , Pradeep Natarajan

Risk of Premature Atherosclerotic Disease in Patients With Monogenic Versus Polygenic Familial Hypercholesterolemia.

Journal of the American College of Cardiology

Avec: Mark Trinder , Xuan Li , Maria Liza DeCastro , Luba Cermakova , Singh Sadananda , Linda M Jackson , Hawmid Azizi , G B John Mancini , Gordon A Francis , Jiri Frohlich , Liam R Brunham

Molecular regulation of plasma lipid levels during systemic inflammation and sepsis.

Current opinion in lipidology

Avec: Mark Trinder , John H Boyd , Liam R Brunham

Cholesteryl Ester Transfer Protein Influences High-Density Lipoprotein Levels and Survival in Sepsis.

American journal of respiratory and critical care medicine

Avec: Mark Trinder , Kelly R Genga , HyeJin Julia Kong , Lisanne L Blauw , Cody Lo , Xuan Li , Mihai Cirstea , Yanan Wang , Patrick C N Rensen , James A Russell , Keith R Walley , John H Boyd , Liam R Brunham

Familial Hypercholesterolemia, Familial Combined Hyperlipidemia, and Elevated Lipoprotein(a) in Patients With Premature Coronary Artery Disease.

The Canadian journal of cardiology

Avec: Diana N Vikulova , Mark Trinder , G B John Mancini , Simon N Pimstone , Liam R Brunham

Polygenic architecture and cardiovascular risk of familial combined hyperlipidemia.

Atherosclerosis

Avec: Mark Trinder , Diana Vikulova , Simon Pimstone , G B John Mancini , Liam R Brunham

Polygenic risk scores for the diagnosis and management of dyslipidemia.

Current opinion in endocrinology, diabetes, and obesity

Avec: Liam R Brunham , Mark Trinder

Effect of the LDL receptor mutation type on incident major adverse cardiovascular events in familial hypercholesterolaemia.

European journal of preventive cardiology

Avec: Martine Paquette , Alain Carrié , Sophie Bernard , Bertrand Cariou , Robert A Hegele , Jacques Genest , Mark Trinder , Liam R Brunham , Sophie Béliard , Alexis Baass

Genetic and clinical factors underlying a self-reported family history of heart disease.

European journal of preventive cardiology

Avec: Amanda R Jowell , Romit Bhattacharya , Christopher Marnell , Megan Wong , Sara Haidermota , Mark Trinder , Akl C Fahed , Gina M Peloso , Michael C Honigberg , Pradeep Natarajan

Novel Management of Peri-Aortitis after Endovascular Repair of Abdominal Aortic Aneurysm.

EJVES short reports

Avec: Matthew Trinder , Bibombe P Mwipatayi , Teck Siew , Andrew Lim , Nishath Altaf

Ascertainment Bias in the Association Between Elevated Lipoprotein(a) and Familial Hypercholesterolemia.

Journal of the American College of Cardiology

Avec: Mark Trinder , Maria L DeCastro , Hawmid Azizi , Luba Cermakova , Linda M Jackson , Jiri Frohlich , G B John Mancini , Gordon A Francis , Liam R Brunham

Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction.

Nature communications

Avec: Jacqueline Saw , Min-Lee Yang , Mark Trinder , Catherine Tcheandjieu , Chang Xu , Andrew Starovoytov , Isabelle Birt , Michael R Mathis , Kristina L Hunker , Ellen M Schmidt , Linda Jackson , Natalia Fendrikova-Mahlay , Matthew Zawistowski , Chad M Brummett , Sebastian Zoellner , Alexander Katz , Dawn M Coleman , Kirby Swan , Christopher J O'Donnell , Auteur inconnu , Xiang Zhou , Jun Z Li , Heather L Gornik , Themistocles L Assimes , James C Stanley , Liam R Brunham , Santhi K Ganesh

Causal Inference for Genetically Determined Levels of High-Density Lipoprotein Cholesterol and Risk of Infectious Disease.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Mark Trinder , Keith R Walley , John H Boyd , Liam R Brunham

Clinical Utility of Lipoprotein(a) and LPA Genetic Risk Score in Risk Prediction of Incident Atherosclerotic Cardiovascular Disease.

JAMA cardiology

Avec: Mark Trinder , Md Mesbah Uddin , Phoebe Finneran , Krishna G Aragam , Pradeep Natarajan

Polygenic Contribution to Low-Density Lipoprotein Cholesterol Levels and Cardiovascular Risk in Monogenic Familial Hypercholesterolemia.

Circulation. Genomic and precision medicine

Avec: Mark Trinder , Martine Paquette , Lubomira Cermakova , Matthew R Ban , Robert A Hegele , Alexis Baass , Liam R Brunham

Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis.

Circulation

Avec: Mark Trinder , Yanan Wang , Christian M Madsen , Tatjana Ponomarev , Lubos Bohunek , Brendan A Daisely , HyeJin Julia Kong , Lisanne L Blauw , Børge G Nordestgaard , Anne Tybjærg-Hansen , Mark M Wurfel , James A Russell , Keith R Walley , Patrick C N Rensen , John H Boyd , Liam R Brunham

Overview of the Canadian Clinician Investigator Trainees' research presented at the 2019 CSCI-CITAC Joint Meeting.

Clinical and investigative medicine. Medecine clinique et experimentale

Avec: Valera Castanov , Tianwei E Zhou , Christopher S Balestrini , Cory Lefebvre , Elina K Cook , Heather T Whittaker , Jillian Macklin , Joel N Briard , Julieta Lazarte , Mark Trinder , Matthaeus A Ware , Sophie Hu , Adam Pietrobon , Tina B Marvasti , Mylvaganam Sivakami

Transient C5 Sensory and Motor Blockade After a Unilateral T4 Paravertebral Block: A Case Report.

A&A practice

Avec: Siavash Mortazavi , Matthew Trinder , Ran Li , Brien Hennessy , Allen Yeo

Genome-wide and phenome-wide analysis of ideal cardiovascular health in the VA Million Veteran Program.

PloS one

Avec: Rose D L Huang , Xuan-Mai T Nguyen , Gina M Peloso , Mark Trinder , Daniel C Posner , Krishna G Aragam , Yuk-Lam Ho , Julie A Lynch , Scott M Damrauer , Kyong-Mi Chang , Philip S Tsao , Pradeep Natarajan , Themistocles Assimes , J Michael Gaziano , Luc Djousse , Kelly Cho , Peter W F Wilson , Jennifer E Huffman , Christopher J O'Donnell , Auteur inconnu

Nature cardiovascular research

Avec: Seyedeh M Zekavat , Vanesa Viana-Huete , Nuria Matesanz , Saman Doroodgar Jorshery , María A Zuriaga , Md Mesbah Uddin , Mark Trinder , Kaavya Paruchuri , Virginia Zorita , Alba Ferrer-Pérez , Marta Amorós-Pérez , Paolo Kunderfranco , Roberta Carriero , Carolina M Greco , Alejandra Aroca-Crevillen , Andrés Hidalgo , Scott M Damrauer , Christie M Ballantyne , Abhishek Niroula , Christopher J Gibson , James Pirruccello , Gabriel Griffin , Benjamin L Ebert , Peter Libby , Valentín Fuster , Hongyu Zhao , Marzyeh Ghassemi , Pradeep Natarajan , Alexander G Bick , José J Fuster , Derek Klarin

Réseau de co-auteurs

Liam R Brunham 22 collaborations

Pradeep Natarajan 10 collaborations

Robert A Hegele 7 collaborations

Michael C Honigberg 5 collaborations

Martine Paquette 5 collaborations

Alexis Baass 5 collaborations

Sara Haidermota 5 collaborations

Md Mesbah Uddin 4 collaborations

Kaavya Paruchuri 4 collaborations

Lubomira Cermakova 4 collaborations

Jacques Genest 4 collaborations

G B John Mancini 4 collaborations

John H Boyd 4 collaborations

Gordon A Francis 3 collaborations

Matthew Trinder 3 collaborations

Bertrand Cariou 3 collaborations

Sophie Bernard 3 collaborations

Sophie Béliard 3 collaborations

Jian Wang 3 collaborations

None None 3 collaborations

Gina M Peloso 3 collaborations

Keith R Walley 3 collaborations

Abhishek Niroula 2 collaborations

Alexander G Bick 2 collaborations

Christopher J Gibson 2 collaborations

Seyedeh M Zekavat 2 collaborations

Benjamin L Ebert 2 collaborations

Seyedeh Maryam Zekavat 2 collaborations

Satoshi Koyama 2 collaborations

Hongyu Zhao 2 collaborations

Margaret Sunitha Selvaraj 2 collaborations

Aniruddh P Patel 2 collaborations

Sarah M Urbut 2 collaborations

Linda Jackson 2 collaborations

Alain Carrié 2 collaborations

Rachel Bernardo 2 collaborations

Thomas Gilliland 2 collaborations

Xuan Li 2 collaborations

Luba Cermakova 2 collaborations

Linda M Jackson 2 collaborations

Hawmid Azizi 2 collaborations

Jiri Frohlich 2 collaborations

HyeJin Julia Kong 2 collaborations

Lisanne L Blauw 2 collaborations

Yanan Wang 2 collaborations

Patrick C N Rensen 2 collaborations

James A Russell 2 collaborations

Christopher J O'Donnell 2 collaborations

Krishna G Aragam 2 collaborations

Scott M Damrauer 2 collaborations

Kate Huang 1 collaboration

Thomas M Roston 1 collaboration

Zachary W Laksman 1 collaboration

Aswin Sekar 1 collaboration

Mark A Murakami 1 collaboration

Mridul Agrawal 1 collaboration

Waihay J Wong 1 collaboration

Gabriel K Griffin 1 collaboration

Miles Marchand 1 collaboration

Victoria Chen 1 collaboration

Talia Shepherd 1 collaboration

Mary Theophilus 1 collaboration

Antonio Gallo 1 collaboration

Brendan A Daisley 1 collaboration

Marc Monachese 1 collaboration

Jordan E Bisanz 1 collaboration

John A Chmiel 1 collaboration

Jeremy P Burton 1 collaboration

Gregor Reid 1 collaboration

Vineet K Raghu 1 collaboration

Yixuan Ye 1 collaboration

Zhi Yu 1 collaboration

Akhil Pampana 1 collaboration

Sarah Urbut 1 collaboration

Declan P O'Regan 1 collaboration

Patrick T Ellinor 1 collaboration

Ayellet V Segrè 1 collaboration

Tobias Elze 1 collaboration

Janey L Wiggs 1 collaboration

James Martone 1 collaboration

Ron A Adelman 1 collaboration

Nazlee Zebardast 1 collaboration

Lucian Del Priore 1 collaboration

Jay C Wang 1 collaboration

Buu Truong 1 collaboration

Raiyan R Khan 1 collaboration

Brenda Xiao 1 collaboration

Laxmi Bhatta 1 collaboration

Ha My T Vy 1 collaboration

Rafael F Guerrero 1 collaboration

Art Schuermans 1 collaboration

So Mi Jemma Cho 1 collaboration

Shamsudheen Karuthedath Vellarikkal 1 collaboration

Kathryn J Gray 1 collaboration

Ben M Brumpton 1 collaboration

Snehal Patil 1 collaboration

Sebastian Zöllner 1 collaboration

Mariah C Antopia 1 collaboration

Richa Saxena 1 collaboration

Girish N Nadkarni 1 collaboration

Ron Do 1 collaboration

Qi Yan 1 collaboration

Itsik Pe'er 1 collaboration

Shefali Setia Verma 1 collaboration

Rajat M Gupta 1 collaboration

David M Haas 1 collaboration

Hilary C Martin 1 collaboration

David A van Heel 1 collaboration

Triin Laisk 1 collaboration

Ahsen Chaudhry 1 collaboration

Kristin Vesely 1 collaboration

Isabelle Ruel 1 collaboration

Brooke A Kennedy 1 collaboration

Adam I Kramer 1 collaboration

Joana R Chora 1 collaboration

Michael A Iacocca 1 collaboration

Lukáš Tichý 1 collaboration

Hannah Wand 1 collaboration

C Lisa Kurtz 1 collaboration

Heather Zimmermann 1 collaboration

Annette Leon 1 collaboration

Maggie Williams 1 collaboration

Steve E Humphries 1 collaboration

Amanda J Hooper 1 collaboration

Alexandre Costa Pereira 1 collaboration

Cinthia E Jannes 1 collaboration

Margaret Chen 1 collaboration

Jessica Chonis 1 collaboration

Serra Kim 1 collaboration

Tami Johnston 1 collaboration

Premysl Soucek 1 collaboration

Michal Kramarek 1 collaboration

Sarah E Leigh 1 collaboration

Eric J Sijbrands 1 collaboration

Tomáš Freiberger 1 collaboration

Joshua W Knowles 1 collaboration

Mafalda Bourbon 1 collaboration

James Januzzi 1 collaboration

Laurens F Reeskamp 1 collaboration

Tycho R Tromp 1 collaboration

Shirin Ibrahim 1 collaboration

G Kees Hovingh 1 collaboration

Erik S G Stroes 1 collaboration

Amit V Khera 1 collaboration

Jacqueline S Dron 1 collaboration

Maria Liza DeCastro 1 collaboration

Singh Sadananda 1 collaboration

Kelly R Genga 1 collaboration

Cody Lo 1 collaboration

Mihai Cirstea 1 collaboration

Diana N Vikulova 1 collaboration

Simon N Pimstone 1 collaboration

Diana Vikulova 1 collaboration

Simon Pimstone 1 collaboration

Amanda R Jowell 1 collaboration

Romit Bhattacharya 1 collaboration

Christopher Marnell 1 collaboration

Megan Wong 1 collaboration

Akl C Fahed 1 collaboration

Bibombe P Mwipatayi 1 collaboration

Teck Siew 1 collaboration

Andrew Lim 1 collaboration

Nishath Altaf 1 collaboration

Maria L DeCastro 1 collaboration

Jacqueline Saw 1 collaboration

Min-Lee Yang 1 collaboration

Catherine Tcheandjieu 1 collaboration

Chang Xu 1 collaboration

Andrew Starovoytov 1 collaboration

Isabelle Birt 1 collaboration

Michael R Mathis 1 collaboration

Kristina L Hunker 1 collaboration

Ellen M Schmidt 1 collaboration

Natalia Fendrikova-Mahlay 1 collaboration

Matthew Zawistowski 1 collaboration

Chad M Brummett 1 collaboration

Sebastian Zoellner 1 collaboration

Alexander Katz 1 collaboration

Dawn M Coleman 1 collaboration

Kirby Swan 1 collaboration

Xiang Zhou 1 collaboration

Jun Z Li 1 collaboration

Heather L Gornik 1 collaboration

Themistocles L Assimes 1 collaboration

James C Stanley 1 collaboration

Santhi K Ganesh 1 collaboration

Phoebe Finneran 1 collaboration

Matthew R Ban 1 collaboration

Christian M Madsen 1 collaboration

Tatjana Ponomarev 1 collaboration

Lubos Bohunek 1 collaboration

Brendan A Daisely 1 collaboration

Børge G Nordestgaard 1 collaboration

Anne Tybjærg-Hansen 1 collaboration

Mark M Wurfel 1 collaboration

Valera Castanov 1 collaboration

Tianwei E Zhou 1 collaboration

Christopher S Balestrini 1 collaboration

Cory Lefebvre 1 collaboration

Elina K Cook 1 collaboration

Heather T Whittaker 1 collaboration

Jillian Macklin 1 collaboration

Joel N Briard 1 collaboration

Julieta Lazarte 1 collaboration

Matthaeus A Ware 1 collaboration

Sophie Hu 1 collaboration

Adam Pietrobon 1 collaboration

Tina B Marvasti 1 collaboration

Mylvaganam Sivakami 1 collaboration

Siavash Mortazavi 1 collaboration

Ran Li 1 collaboration

Brien Hennessy 1 collaboration

Allen Yeo 1 collaboration

Rose D L Huang 1 collaboration

Xuan-Mai T Nguyen 1 collaboration

Daniel C Posner 1 collaboration

Yuk-Lam Ho 1 collaboration

Julie A Lynch 1 collaboration

Kyong-Mi Chang 1 collaboration

Philip S Tsao 1 collaboration

Themistocles Assimes 1 collaboration

J Michael Gaziano 1 collaboration

Luc Djousse 1 collaboration

Kelly Cho 1 collaboration

Peter W F Wilson 1 collaboration

Jennifer E Huffman 1 collaboration

Vanesa Viana-Huete 1 collaboration

Nuria Matesanz 1 collaboration

Saman Doroodgar Jorshery 1 collaboration

María A Zuriaga 1 collaboration

Virginia Zorita 1 collaboration

Alba Ferrer-Pérez 1 collaboration

Marta Amorós-Pérez 1 collaboration

Paolo Kunderfranco 1 collaboration

Roberta Carriero 1 collaboration

Carolina M Greco 1 collaboration

Alejandra Aroca-Crevillen 1 collaboration

Andrés Hidalgo 1 collaboration

Christie M Ballantyne 1 collaboration

James Pirruccello 1 collaboration

Gabriel Griffin 1 collaboration

Peter Libby 1 collaboration

Valentín Fuster 1 collaboration

Marzyeh Ghassemi 1 collaboration

José J Fuster 1 collaboration

Derek Klarin 1 collaboration