Nadia Messaddeq

Affiliations

Institut de Génétique et Biologie Moléculaire et Cellulaire (IGBMC), INSERM U1258, CNRS UMR 7104, Université de Strasbourg, Illkirch, France.

Publications (25)

Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection.

Nature communications

Avec: Marion Ferren , Valérie Favède , Didier Decimo , Mathieu Iampietro , Nicole A P Lieberman , Jean-Luc Weickert , Rodolphe Pelissier , Magalie Mazelier , Olivier Terrier , Anne Moscona , Matteo Porotto , Alexander L Greninger , Nadia Messaddeq , Branka Horvat , Cyrille Mathieu

Differential impact of ubiquitous and muscle dynamin 2 isoforms in muscle physiology and centronuclear myopathy.

Nature communications

Avec: Raquel Gómez-Oca , Evelina Edelweiss , Sarah Djeddi , Mathias Gerbier , Xènia Massana-Muñoz , Mustapha Oulad-Abdelghani , Corinne Crucifix , Coralie Spiegelhalter , Nadia Messaddeq , Pierre Poussin-Courmontagne , Pascale Koebel , Belinda S Cowling , Jocelyn Laporte

Polyglutamine-expanded ATXN7 alters a specific epigenetic signature underlying photoreceptor identity gene expression in SCA7 mouse retinopathy.

Journal of biomedical science

Avec: Anna Niewiadomska-Cimicka , Antoine Hache , Stéphanie Le Gras , Céline Keime , Tao Ye , Aurelie Eisenmann , Imen Harichane , Michel J Roux , Nadia Messaddeq , Emmanuelle Clérin , Thierry Léveillard , Yvon Trottier

MTM1 overexpression prevents and reverts BIN1-related centronuclear myopathy.

Brain : a journal of neurology

Avec: Quentin Giraud , Coralie Spiegelhalter , Nadia Messaddeq , Jocelyn Laporte

High Levels of Frataxin Overexpression Lead to Mitochondrial and Cardiac Toxicity in Mouse Models.

Molecular therapy. Methods & clinical development

Avec: Brahim Belbellaa , Laurence Reutenauer , Nadia Messaddeq , Laurent Monassier , Hélène Puccio

SCA7 Mouse Cerebellar Pathology Reveals Preferential Downregulation of Key Purkinje Cell-Identity Genes and Shared Disease Signature with SCA1 and SCA2.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Avec: Anna Niewiadomska-Cimicka , Frédéric Doussau , Jean-Baptiste Perot , Michel J Roux , Celine Keime , Antoine Hache , Françoise Piguet , Ariana Novati , Chantal Weber , Binnaz Yalcin , Hamid Meziane , Marie-France Champy , Erwan Grandgirard , Alice Karam , Nadia Messaddeq , Aurélie Eisenmann , Emmanuel Brouillet , Hoa Huu Phuc Nguyen , Julien Flament , Philippe Isope , Yvon Trottier

In vivo phenotypic and molecular characterization of retinal degeneration in mouse models of three ciliopathies.

Experimental eye research

Avec: Agnès Brun , Xiangxiang Yu , Cathy Obringer , Daniel Ajoy , Elodie Haser , Corinne Stoetzel , Michel J Roux , Nadia Messaddeq , Hélène Dollfus , Vincent Marion

Reproduction Function in Male Patients With Bardet Biedl Syndrome.

The Journal of clinical endocrinology and metabolism

Avec: Isabelle Koscinski , Manuel Mark , Nadia Messaddeq , Jean-Jacques Braun , Catherine Celebi , Jean Muller , Anna Zinetti-Bertschy , Nathalie Goetz , Hélène Dollfus , Sylvie Rossignol

Intraoperative imaging for remnant viability assessment in bilateral posterior retroperitoneoscopic partial adrenalectomy in an experimental model.

The British journal of surgery

Avec: B Seeliger , P F Alesina , M K Walz , R Pop , A-L Charles , B Geny , N Messaddeq , G Kontogeorgos , P Mascagni , E Seyller , J Marescaux , V Agnus , M Diana

Mice with muscle-specific deletion of Bin1 recapitulate centronuclear myopathy and acute downregulation of dynamin 2 improves their phenotypes.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Roberto Silva-Rojas , Vasugi Nattarayan , Francisco Jaque-Fernandez , Raquel Gomez-Oca , Alexia Menuet , David Reiss , Marie Goret , Nadia Messaddeq , Valentina M Lionello , Christine Kretz , Belinda S Cowling , Vincent Jacquemond , Jocelyn Laporte

Correction: Pickering nano-emulsions stabilized by solid lipid nanoparticles as a temperature sensitive drug delivery system.

Soft matter

Avec: Sidy Mouhamed Dieng , Nicolas Anton , Patrick Bouriat , Oumar Thioune , Papa Mady Sy , Nadia Messaddeq , Said Ennahar , Mounibé Diarra , Thierry Vandamme

STIM1 over-activation generates a multi-systemic phenotype affecting the skeletal muscle, spleen, eye, skin, bones and immune system in mice.

Human molecular genetics

Avec: Roberto Silva-Rojas , Susan Treves , Hugues Jacobs , Pascal Kessler , Nadia Messaddeq , Jocelyn Laporte , Johann Böhm

Relative Adipose Tissue Failure in Alström Syndrome Drives Obesity-Induced Insulin Resistance.

Diabetes

Avec: Tarekegn Geberhiwot , Shanat Baig , Cathy Obringer , Dorothée Girard , Charlotte Dawson , Konstantinos Manolopoulos , Nadia Messaddeq , Pierre Bel Lassen , Karine Clement , Jeremy W Tomlinson , Richard P Steeds , Hélène Dollfus , Nikolai Petrovsky , Vincent Marion

Tunable functionalization of nano-emulsions using amphiphilic polymers.

Soft matter

Avec: Asad Ur Rehman , Nicolas Anton , Sophie Bou , Jérémy Schild , Nadia Messaddeq , Thierry Vandamme , Salman Akram , Andrey Klymchenko , Mayeul Collot

Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice.

Science translational medicine

Avec: Valentina M Lionello , Anne-Sophie Nicot , Maxime Sartori , Christine Kretz , Pascal Kessler , Suzie Buono , Sarah Djerroud , Nadia Messaddeq , Pascale Koebel , Ivana Prokic , Yann Hérault , Norma B Romero , Jocelyn Laporte , Belinda S Cowling

Loss of zebrafish Ataxin-7, a SAGA subunit responsible for SCA7 retinopathy, causes ocular coloboma and malformation of photoreceptors.

Human molecular genetics

Avec: Samantha Carrillo-Rosas , Chantal Weber , Lorraine Fievet , Nadia Messaddeq , Alice Karam , Yvon Trottier

Abnormal lipid storage related to adipocyte shrinkage in acquired partial lipodystrophy (Barraquer-Simons syndrome).

Journal of the European Academy of Dermatology and Venereology : JEADV

Avec: C Velter , N Messaddeq , E Levy , C Morruzzi , B Cribier , N Dali-Youcef , D Lipsker

Cardiac forces regulate zebrafish heart valve delamination by modulating Nfat signaling.

PLoS biology

Avec: Renee Wei-Yan Chow , Hajime Fukui , Wei Xuan Chan , Kok Soon Justin Tan , Stéphane Roth , Anne-Laure Duchemin , Nadia Messaddeq , Hiroyuki Nakajima , Fei Liu , Nathalie Faggianelli-Conrozier , Andrey S Klymchenko , Yap Choon Hwai , Naoki Mochizuki , Julien Vermot

PATAS, a First-in-Class Therapeutic Peptide Biologic, Improves Whole-Body Insulin Resistance and Associated Comorbidities In Vivo.

Diabetes

Avec: Edwige Schreyer , Cathy Obringer , Nadia Messaddeq , Bruno Kieffer , Paul Zimmet , Alexander Fleming , Tarekegn Geberhiwot , Vincent Marion

Pickering nano-emulsions stabilized by Eudragit RL100 nanoparticles as oral drug delivery system for poorly soluble drugs.

Colloids and surfaces. B, Biointerfaces

Avec: Sidy Mouhamed Dieng , Ziad Omran , Nicolas Anton , Oumar Thioune , Alphonse Rodrigue Djiboune , Papa Mady Sy , Nadia Messaddeq , Said Ennahar , Mounibé Diarra , Thierry Vandamme

FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis.

Nature neuroscience

Avec: Gina Picchiarelli , Maria Demestre , Amila Zuko , Marije Been , Julia Higelin , Stéphane Dieterlé , Marc-Antoine Goy , Moushami Mallik , Chantal Sellier , Jelena Scekic-Zahirovic , Li Zhang , Angela Rosenbohm , Céline Sijlmans , Amr Aly , Sina Mersmann , Inmaculada Sanjuan-Ruiz , Annemarie Hübers , Nadia Messaddeq , Marina Wagner , Nick van Bakel , Anne-Laurence Boutillier , Albert Ludolph , Clotilde Lagier-Tourenne , Tobias M Boeckers , Luc Dupuis , Erik Storkebaum

Toward the Formulation of Stable Micro and Nano Double Emulsions through a Silica Coating on Internal Water Droplets.

Langmuir : the ACS journal of surfaces and colloids

Avec: Salman Akram , Xinyue Wang , Thierry F Vandamme , Mayeul Collot , Asad Ur Rehman , Nadia Messaddeq , Yves Mély , Nicolas Anton

Magnetite- and Iodine-Containing Nanoemulsion as a Dual Modal Contrast Agent for X-ray/Magnetic Resonance Imaging.

ACS applied materials & interfaces

Avec: Justine Wallyn , Nicolas Anton , Damien Mertz , Sylvie Begin-Colin , Francis Perton , Christophe A Serra , Florence Franconi , Laurent Lemaire , Manuela Chiper , Hélène Libouban , Nadia Messaddeq , Halina Anton , Thierry F Vandamme

BIN1 modulation in vivo rescues dynamin-related myopathy.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Valentina Maria Lionello , Christine Kretz , Evelina Edelweiss , Corinne Crucifix , Raquel Gómez-Oca , Nadia Messaddeq , Suzie Buono , Pascale Koebel , Xènia Massana Muñoz , Nadège Diedhiou , Belinda S Cowling , Marc Bitoun , Jocelyn Laporte

Androgen receptor coordinates muscle metabolic and contractile functions.

Journal of cachexia, sarcopenia and muscle

Avec: Kamar Ghaibour , Mélanie Schuh , Sirine Souali-Crespo , Céline Chambon , Anouk Charlot , Joe Rizk , Daniela Rovito , Anna-Isavella Rerra , Qingshuang Cai , Nadia Messaddeq , Joffrey Zoll , Delphine Duteil , Daniel Metzger

Réseau de co-auteurs

Jocelyn Laporte 6 collaborations

Nicolas Anton 5 collaborations

Belinda S Cowling 4 collaborations

Pascale Koebel 3 collaborations

Michel J Roux 3 collaborations

Yvon Trottier 3 collaborations

Cathy Obringer 3 collaborations

Hélène Dollfus 3 collaborations

Vincent Marion 3 collaborations

Christine Kretz 3 collaborations

Thierry Vandamme 3 collaborations

Raquel Gómez-Oca 2 collaborations

Evelina Edelweiss 2 collaborations

Corinne Crucifix 2 collaborations

Coralie Spiegelhalter 2 collaborations

Anna Niewiadomska-Cimicka 2 collaborations

Antoine Hache 2 collaborations

Chantal Weber 2 collaborations

Alice Karam 2 collaborations

N Messaddeq 2 collaborations

Roberto Silva-Rojas 2 collaborations

Valentina M Lionello 2 collaborations

Sidy Mouhamed Dieng 2 collaborations

Oumar Thioune 2 collaborations

Papa Mady Sy 2 collaborations

Said Ennahar 2 collaborations

Mounibé Diarra 2 collaborations

Pascal Kessler 2 collaborations

Tarekegn Geberhiwot 2 collaborations

Asad Ur Rehman 2 collaborations

Salman Akram 2 collaborations

Mayeul Collot 2 collaborations

Suzie Buono 2 collaborations

Thierry F Vandamme 2 collaborations

Marion Ferren 1 collaboration

Valérie Favède 1 collaboration

Didier Decimo 1 collaboration

Mathieu Iampietro 1 collaboration

Nicole A P Lieberman 1 collaboration

Jean-Luc Weickert 1 collaboration

Rodolphe Pelissier 1 collaboration

Magalie Mazelier 1 collaboration

Olivier Terrier 1 collaboration

Anne Moscona 1 collaboration

Matteo Porotto 1 collaboration

Alexander L Greninger 1 collaboration

Branka Horvat 1 collaboration

Cyrille Mathieu 1 collaboration

Sarah Djeddi 1 collaboration

Mathias Gerbier 1 collaboration

Xènia Massana-Muñoz 1 collaboration

Mustapha Oulad-Abdelghani 1 collaboration

Pierre Poussin-Courmontagne 1 collaboration

Stéphanie Le Gras 1 collaboration

Céline Keime 1 collaboration

Tao Ye 1 collaboration

Aurelie Eisenmann 1 collaboration

Imen Harichane 1 collaboration

Emmanuelle Clérin 1 collaboration

Thierry Léveillard 1 collaboration

Quentin Giraud 1 collaboration

Brahim Belbellaa 1 collaboration

Laurence Reutenauer 1 collaboration

Laurent Monassier 1 collaboration

Hélène Puccio 1 collaboration

Frédéric Doussau 1 collaboration

Jean-Baptiste Perot 1 collaboration

Celine Keime 1 collaboration

Françoise Piguet 1 collaboration

Ariana Novati 1 collaboration

Binnaz Yalcin 1 collaboration

Hamid Meziane 1 collaboration

Marie-France Champy 1 collaboration

Erwan Grandgirard 1 collaboration

Aurélie Eisenmann 1 collaboration

Emmanuel Brouillet 1 collaboration

Hoa Huu Phuc Nguyen 1 collaboration

Julien Flament 1 collaboration

Philippe Isope 1 collaboration

Agnès Brun 1 collaboration

Xiangxiang Yu 1 collaboration

Daniel Ajoy 1 collaboration

Elodie Haser 1 collaboration

Corinne Stoetzel 1 collaboration

Isabelle Koscinski 1 collaboration

Manuel Mark 1 collaboration

Jean-Jacques Braun 1 collaboration

Catherine Celebi 1 collaboration

Jean Muller 1 collaboration

Anna Zinetti-Bertschy 1 collaboration

Nathalie Goetz 1 collaboration

Sylvie Rossignol 1 collaboration

B Seeliger 1 collaboration

P F Alesina 1 collaboration

M K Walz 1 collaboration

R Pop 1 collaboration

A-L Charles 1 collaboration

B Geny 1 collaboration

G Kontogeorgos 1 collaboration

P Mascagni 1 collaboration

E Seyller 1 collaboration

J Marescaux 1 collaboration

V Agnus 1 collaboration

M Diana 1 collaboration

Vasugi Nattarayan 1 collaboration

Francisco Jaque-Fernandez 1 collaboration

Raquel Gomez-Oca 1 collaboration

Alexia Menuet 1 collaboration

David Reiss 1 collaboration

Marie Goret 1 collaboration

Vincent Jacquemond 1 collaboration

Patrick Bouriat 1 collaboration

Susan Treves 1 collaboration

Hugues Jacobs 1 collaboration

Johann Böhm 1 collaboration

Shanat Baig 1 collaboration

Dorothée Girard 1 collaboration

Charlotte Dawson 1 collaboration

Konstantinos Manolopoulos 1 collaboration

Pierre Bel Lassen 1 collaboration

Karine Clement 1 collaboration

Jeremy W Tomlinson 1 collaboration

Richard P Steeds 1 collaboration

Nikolai Petrovsky 1 collaboration

Sophie Bou 1 collaboration

Jérémy Schild 1 collaboration

Andrey Klymchenko 1 collaboration

Anne-Sophie Nicot 1 collaboration

Maxime Sartori 1 collaboration

Sarah Djerroud 1 collaboration

Ivana Prokic 1 collaboration

Yann Hérault 1 collaboration

Norma B Romero 1 collaboration

Samantha Carrillo-Rosas 1 collaboration

Lorraine Fievet 1 collaboration

C Velter 1 collaboration

E Levy 1 collaboration

C Morruzzi 1 collaboration

B Cribier 1 collaboration

N Dali-Youcef 1 collaboration

D Lipsker 1 collaboration

Renee Wei-Yan Chow 1 collaboration

Hajime Fukui 1 collaboration

Wei Xuan Chan 1 collaboration

Kok Soon Justin Tan 1 collaboration

Stéphane Roth 1 collaboration

Anne-Laure Duchemin 1 collaboration

Hiroyuki Nakajima 1 collaboration

Fei Liu 1 collaboration

Nathalie Faggianelli-Conrozier 1 collaboration

Andrey S Klymchenko 1 collaboration

Yap Choon Hwai 1 collaboration

Naoki Mochizuki 1 collaboration

Julien Vermot 1 collaboration

Edwige Schreyer 1 collaboration

Bruno Kieffer 1 collaboration

Paul Zimmet 1 collaboration

Alexander Fleming 1 collaboration

Ziad Omran 1 collaboration

Alphonse Rodrigue Djiboune 1 collaboration

Gina Picchiarelli 1 collaboration

Maria Demestre 1 collaboration

Amila Zuko 1 collaboration

Marije Been 1 collaboration

Julia Higelin 1 collaboration

Stéphane Dieterlé 1 collaboration

Marc-Antoine Goy 1 collaboration

Moushami Mallik 1 collaboration

Chantal Sellier 1 collaboration

Jelena Scekic-Zahirovic 1 collaboration

Li Zhang 1 collaboration

Angela Rosenbohm 1 collaboration

Céline Sijlmans 1 collaboration

Amr Aly 1 collaboration

Sina Mersmann 1 collaboration

Inmaculada Sanjuan-Ruiz 1 collaboration

Annemarie Hübers 1 collaboration

Marina Wagner 1 collaboration

Nick van Bakel 1 collaboration

Anne-Laurence Boutillier 1 collaboration

Albert Ludolph 1 collaboration

Clotilde Lagier-Tourenne 1 collaboration

Tobias M Boeckers 1 collaboration

Luc Dupuis 1 collaboration

Erik Storkebaum 1 collaboration

Xinyue Wang 1 collaboration

Yves Mély 1 collaboration

Justine Wallyn 1 collaboration

Damien Mertz 1 collaboration

Sylvie Begin-Colin 1 collaboration

Francis Perton 1 collaboration

Christophe A Serra 1 collaboration

Florence Franconi 1 collaboration

Laurent Lemaire 1 collaboration

Manuela Chiper 1 collaboration

Hélène Libouban 1 collaboration

Halina Anton 1 collaboration

Valentina Maria Lionello 1 collaboration

Xènia Massana Muñoz 1 collaboration

Nadège Diedhiou 1 collaboration

Marc Bitoun 1 collaboration

Kamar Ghaibour 1 collaboration

Mélanie Schuh 1 collaboration

Sirine Souali-Crespo 1 collaboration

Céline Chambon 1 collaboration

Anouk Charlot 1 collaboration

Joe Rizk 1 collaboration

Daniela Rovito 1 collaboration

Anna-Isavella Rerra 1 collaboration

Qingshuang Cai 1 collaboration

Joffrey Zoll 1 collaboration

Delphine Duteil 1 collaboration

Daniel Metzger 1 collaboration