Nicholas Stephanopoulos

Affiliations

Center for Molecular Design and Biomimetics, The Biodesign Institute, School of Molecular Sciences, Arizona State University, Tempe, AZ, 85281, USA.

Publications (40)

Highly Permeable DNA Supramolecular Hydrogel Promotes Neurogenesis and Functional Recovery after Completely Transected Spinal Cord Injury.

Advanced materials (Deerfield Beach, Fla.)

Avec: Taoyang Yuan , Yu Shao , Xu Zhou , Qian Liu , Zhichao Zhu , Bini Zhou , Yuanchen Dong , Nicholas Stephanopoulos , Songbai Gui , Hao Yan , Dongsheng Liu

Protein Corona Inhibits Endosomal Escape of Functionalized DNA Nanostructures in Living Cells.

ACS applied materials & interfaces

Avec: Barbora Smolková , Tara MacCulloch , Tyler F Rockwood , Minghui Liu , Skylar J W Henry , Adam Frtús , Mariia Uzhytchak , Mariia Lunova , Martin Hof , Piotr Jurkiewicz , Alexandr Dejneka , Nicholas Stephanopoulos , Oleg Lunov

Atomistic Picture of Opening-Closing Dynamics of DNA Holliday Junction Obtained by Molecular Simulations.

Journal of chemical information and modeling

Avec: Zhengyue Zhang , Jiří Šponer , Giovanni Bussi , Vojtěch Mlýnský , Petr Šulc , Chad R Simmons , Nicholas Stephanopoulos , Miroslav Krepl

DNA-Nanostructure-Guided Assembly of Proteins into Programmable Shapes.

Nano letters

Avec: Qinyi Lu , Yang Xu , Erik Poppleton , Kun Zhou , Petr Sulc , Nicholas Stephanopoulos , Yonggang Ke

Peptide-coated DNA nanostructures as a platform for control of lysosomal function in cells.

Chemical engineering journal (Lausanne, Switzerland : 1996)

Avec: Petra Elblová , Mariia Lunova , Skylar J W Henry , Xinyi Tu , Alicia Calé , Alexandr Dejneka , Jarmila Havelková , Yuriy Petrenko , Milan Jirsa , Nicholas Stephanopoulos , Oleg Lunov

Reversible Control of Gelatin Hydrogel Stiffness by Using DNA Crosslinkers*.

Chembiochem : a European journal of chemical biology

Avec: Alex Buchberger , Harpinder Saini , Kiarash Rahmani Eliato , Azadeh Zare , Ryan Merkley , Yang Xu , Julio Bernal , Robert Ros , Mehdi Nikkhah , Nicholas Stephanopoulos

Using dynamic biomaterials to study the temporal role of osteogenic growth peptide during osteogenesis.

bioRxiv : the preprint server for biology

Avec: Fallon M Fumasi , Tara MacCulloch , Julio Bernal-Chanchavac , Nicholas Stephanopoulos , Julianne L Holloway

Construction of Reconfigurable and Polymorphic DNA Origami Assemblies with Coiled-Coil Patches and Patterns.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Avec: Teng Teng , Julio Bernal-Chanchavac , Nicholas Stephanopoulos , Carlos E Castro

Hierarchical Assembly of Nucleic Acid/Coiled-Coil Peptide Nanostructures.

Journal of the American Chemical Society

Avec: Alex Buchberger , Chad R Simmons , Nour Eddine Fahmi , Ronit Freeman , Nicholas Stephanopoulos

A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High-Resolution Structural Detail.

Angewandte Chemie (International ed. in English)

Avec: Chad R Simmons , Tara MacCulloch , Fei Zhang , Yan Liu , Nicholas Stephanopoulos , Hao Yan

Label-free detection of conformational changes in switchable DNA nanostructures with microwave microfluidics.

Nature communications

Avec: Angela C Stelson , Minghui Liu , Charles A E Little , Christian J Long , Nathan D Orloff , Nicholas Stephanopoulos , James C Booth

Peptide-Oligonucleotide Hybrid Molecules for Bioactive Nanomaterials.

Bioconjugate chemistry

Avec: Nicholas Stephanopoulos

Nanoscale Structures and Materials from the Self-assembly of Polypeptides and DNA.

Current topics in medicinal chemistry

Avec: Julio Bernal-Chanchavac , Md Al-Amin , Nicholas Stephanopoulos

Functionalizing DNA nanostructures for therapeutic applications.

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology

Avec: Skylar J W Henry , Nicholas Stephanopoulos

Proximity-enhanced synthesis of DNA-peptide-DNA triblock molecules.

Chemical communications (Cambridge, England)

Avec: Tara MacCulloch , Alexandra Novacek , Nicholas Stephanopoulos

Using dynamic biomaterials to study the temporal role of bioactive peptides during osteogenesis.

Biomaterials advances

Avec: Fallon M Fumasi , Tara MacCulloch , Julio Bernal-Chanchavac , Nicholas Stephanopoulos , Julianne L Holloway

Site-Specific Arrangement and Structure Determination of Minor Groove Binding Molecules in Self-Assembled Three-Dimensional DNA Crystals.

Journal of the American Chemical Society

Avec: Chad R Simmons , Alex Buchberger , Skylar J W Henry , Alexandra Novacek , Nour Eddine Fahmi , Tara MacCulloch , Nicholas Stephanopoulos , Hao Yan

Self-Assembly of Hybrid Peptide-DNA Nanostructures using Homotrimeric Coiled-Coil/Nucleic Acid Building Blocks.

Chembiochem : a European journal of chemical biology

Avec: Alex Buchberger , Md Al-Amin , Chad R Simmons , Nicholas Stephanopoulos

Inverse design of a pyrochlore lattice of DNA origami through model-driven experiments.

Science (New York, N.Y.)

Avec: Hao Liu , Michael Matthies , John Russo , Lorenzo Rovigatti , Raghu Pradeep Narayanan , Thong Diep , Daniel McKeen , Oleg Gang , Nicholas Stephanopoulos , Francesco Sciortino , Hao Yan , Flavio Romano , Petr Šulc

Tunable Nanoscale Cages from Self-Assembling DNA and Protein Building Blocks.

ACS nano

Avec: Yang Xu , Shuoxing Jiang , Chad R Simmons , Raghu Pradeep Narayanan , Fei Zhang , Ann-Marie Aziz , Hao Yan , Nicholas Stephanopoulos

Strategies for Stabilizing DNA Nanostructures to Biological Conditions.

Chembiochem : a European journal of chemical biology

Avec: Nicholas Stephanopoulos

Emerging applications of peptide-oligonucleotide conjugates: bioactive scaffolds, self-assembling systems, and hybrid nanomaterials.

Organic & biomolecular chemistry

Avec: Tara MacCulloch , Alex Buchberger , Nicholas Stephanopoulos

The living interface between synthetic biology and biomaterial design.

Nature materials

Avec: Allen P Liu , Eric A Appel , Paul D Ashby , Brendon M Baker , Elisa Franco , Luo Gu , Karmella Haynes , Neel S Joshi , April M Kloxin , Paul H J Kouwer , Jeetain Mittal , Leonardo Morsut , Vincent Noireaux , Sapun Parekh , Rebecca Schulman , Sindy K Y Tang , Megan T Valentine , Sebastián L Vega , Wilfried Weber , Nicholas Stephanopoulos , Ovijit Chaudhuri

Coarse-Grained Simulations for the Characterization and Optimization of Hybrid Protein-DNA Nanostructures.

ACS nano

Avec: Raghu Pradeep Narayanan , Jonah Procyk , Purbasha Nandi , Abhay Prasad , Yang Xu , Erik Poppleton , Dewight Williams , Fei Zhang , Hao Yan , Po-Lin Chiu , Nicholas Stephanopoulos , Petr Šulc

Bioactive Fibronectin-III

ACS applied bio materials

Avec: Alex Buchberger , Kyle Riker , Julio Bernal-Chanchavac , Raghu Pradeep Narayanan , Chad R Simmons , Nour Eddine Fahmi , Ronit Freeman , Nicholas Stephanopoulos

Calcium-triggered DNA-mediated membrane fusion in synthetic cells.

bioRxiv : the preprint server for biology

Avec: Yen-Yu Hsu , Samuel J Chen , Julio Bernal-Chanchavac , Bineet Sharma , Hossein Moghimianavval , Nicholas Stephanopoulos , Allen P Liu

Site-specific arrangement and structure determination of minor groove binding molecules in self-assembled three-dimensional DNA crystals.

bioRxiv : the preprint server for biology

Avec: Chad R Simmons , Alex Buchberger , Skylar J W Henry , Alexandra Novacek , Nour Eddine Fahmi , Tara MacCulloch , Nicholas Stephanopoulos , Hao Yan

High-affinity binding to the SARS-CoV-2 spike trimer by a nanostructured, trivalent protein-DNA synthetic antibody.

bioRxiv : the preprint server for biology

Avec: Yang Xu , Rong Zheng , Abhay Prasad , Minghui Liu , Zijian Wan , Xiaoyan Zhou , Ryan M Porter , Matthew Sample , Erik Poppleton , Jonah Procyk , Hao Liu , Yize Li , Shaopeng Wang , Hao Yan , Petr Sulc , Nicholas Stephanopoulos

Templating Peptide Chemistry with Nucleic Acids: Toward Artificial Ribosomes, Cell-Specific Therapeutics, and Novel Protein-Mimetic Architectures.

Biomacromolecules

Avec: Alexandra Novacek , Bryan Ugaz , Nicholas Stephanopoulos

Progress toward sourcing plants for new bioconjugation tools: a screening evaluation of a model peptide ligase using a synthetic precursor.

3 Biotech

Avec: Tunjung Mahatmanto , Isyatul Azizah , Alex Buchberger , Nicholas Stephanopoulos

Programmable, self-assembled DNA nanodevices for cellular programming and tissue engineering.

Nanoscale

Avec: Ankit Gangrade , Nicholas Stephanopoulos , Dhiraj Bhatia

Reversible control of biomaterial properties for dynamically tuning cell behavior.

Journal of applied polymer science

Avec: Fallon M Fumasi , Nicholas Stephanopoulos , Julianne L Holloway

The interactions between DNA nanostructures and cells: A critical overview from a cell biology perspective.

Acta biomaterialia

Avec: Adam Frtús , Barbora Smolková , Mariia Uzhytchak , Mariia Lunova , Milan Jirsa , Skylar J W Henry , Alexandr Dejneka , Nicholas Stephanopoulos , Oleg Lunov

The influence of Holliday junction sequence and dynamics on DNA crystal self-assembly.

Nature communications

Avec: Chad R Simmons , Tara MacCulloch , Miroslav Krepl , Michael Matthies , Alex Buchberger , Ilyssa Crawford , Jiří Šponer , Petr Šulc , Nicholas Stephanopoulos , Hao Yan

Uncovering temporospatial sensitive TBI targeting strategies via in vivo phage display.

Science advances

Avec: Briana I Martinez , Gergey Alzaem Mousa , Kiera Fleck , Tara MacCulloch , Chris W Diehnelt , Nicholas Stephanopoulos , Sarah E Stabenfeldt

Calcium-triggered DNA-mediated membrane fusion in synthetic cells.

Chemical communications (Cambridge, England)

Avec: Yen-Yu Hsu , Samuel J Chen , Julio Bernal-Chanchavac , Bineet Sharma , Hossein Moghimianavval , Nicholas Stephanopoulos , Allen P Liu

High-Affinity Host-Guest Recognition for Efficient Assembly and Enzymatic Responsiveness of DNA Nanostructures.

Small (Weinheim an der Bergstrasse, Germany)

Avec: Raghu Pradeep Narayanan , Abhay Prasad , Alex Buchberger , Lei Zou , Julio Bernal-Chanchavac , Tara MacCulloch , Nour Eddine Fahmi , Hao Yan , Fei Zhang , Matthew J Webber , Nicholas Stephanopoulos

Construction and reconfiguration of dynamic DNA origami assemblies with coiled-coil patches and patterns.

bioRxiv : the preprint server for biology

Avec: T Teng , J Bernal-Chanchavac , N Stephanopoulos , C E Castro

CytoDirect: A Nucleic Acid Nanodevice for Specific and Efficient Delivery of Functional Payloads to the Cytoplasm.

Journal of the American Chemical Society

Avec: Lu Yu , Yang Xu , Md Al-Amin , Shuoxing Jiang , Matthew Sample , Abhay Prasad , Nicholas Stephanopoulos , Petr Šulc , Hao Yan

Click-Chemistry-Enabled Functionalization of Cellulose Nanocrystals with Single-Stranded DNA for Directed Assembly.

ACS biomaterials science & engineering

Avec: Daria Bukharina , Katherine Cauffiel , Laura Mae Killingsworth , Justin A Brackenridge , Valeriia Poliukhova , Minkyu Kim , Justin Brower , Julio Bernal-Chanchavac , Nicholas Stephanopoulos , Vladimir V Tsukruk

Réseau de co-auteurs

Hao Yan 11 collaborations

Tara MacCulloch 11 collaborations

Alex Buchberger 10 collaborations

Chad R Simmons 9 collaborations

Julio Bernal-Chanchavac 9 collaborations

Skylar J W Henry 6 collaborations

Yang Xu 6 collaborations

Petr Šulc 5 collaborations

Nour Eddine Fahmi 5 collaborations

Raghu Pradeep Narayanan 5 collaborations

Fei Zhang 4 collaborations

Alexandra Novacek 4 collaborations

Abhay Prasad 4 collaborations

Minghui Liu 3 collaborations

Mariia Lunova 3 collaborations

Alexandr Dejneka 3 collaborations

Oleg Lunov 3 collaborations

Erik Poppleton 3 collaborations

Fallon M Fumasi 3 collaborations

Julianne L Holloway 3 collaborations

Md Al-Amin 3 collaborations

Allen P Liu 3 collaborations

Barbora Smolková 2 collaborations

Adam Frtús 2 collaborations

Mariia Uzhytchak 2 collaborations

Jiří Šponer 2 collaborations

Miroslav Krepl 2 collaborations

Petr Sulc 2 collaborations

Milan Jirsa 2 collaborations

Ronit Freeman 2 collaborations

Hao Liu 2 collaborations

Michael Matthies 2 collaborations

Shuoxing Jiang 2 collaborations

Jonah Procyk 2 collaborations

Yen-Yu Hsu 2 collaborations

Samuel J Chen 2 collaborations

Bineet Sharma 2 collaborations

Hossein Moghimianavval 2 collaborations

Matthew Sample 2 collaborations

Taoyang Yuan 1 collaboration

Yu Shao 1 collaboration

Xu Zhou 1 collaboration

Qian Liu 1 collaboration

Zhichao Zhu 1 collaboration

Bini Zhou 1 collaboration

Yuanchen Dong 1 collaboration

Songbai Gui 1 collaboration

Dongsheng Liu 1 collaboration

Tyler F Rockwood 1 collaboration

Martin Hof 1 collaboration

Piotr Jurkiewicz 1 collaboration

Zhengyue Zhang 1 collaboration

Giovanni Bussi 1 collaboration

Vojtěch Mlýnský 1 collaboration

Qinyi Lu 1 collaboration

Kun Zhou 1 collaboration

Yonggang Ke 1 collaboration

Petra Elblová 1 collaboration

Xinyi Tu 1 collaboration

Alicia Calé 1 collaboration

Jarmila Havelková 1 collaboration

Yuriy Petrenko 1 collaboration

Harpinder Saini 1 collaboration

Kiarash Rahmani Eliato 1 collaboration

Azadeh Zare 1 collaboration

Ryan Merkley 1 collaboration

Julio Bernal 1 collaboration

Robert Ros 1 collaboration

Mehdi Nikkhah 1 collaboration

Teng Teng 1 collaboration

Carlos E Castro 1 collaboration

Yan Liu 1 collaboration

Angela C Stelson 1 collaboration

Charles A E Little 1 collaboration

Christian J Long 1 collaboration

Nathan D Orloff 1 collaboration

James C Booth 1 collaboration

John Russo 1 collaboration

Lorenzo Rovigatti 1 collaboration

Thong Diep 1 collaboration

Daniel McKeen 1 collaboration

Oleg Gang 1 collaboration

Francesco Sciortino 1 collaboration

Flavio Romano 1 collaboration

Ann-Marie Aziz 1 collaboration

Eric A Appel 1 collaboration

Paul D Ashby 1 collaboration

Brendon M Baker 1 collaboration

Elisa Franco 1 collaboration

Luo Gu 1 collaboration

Karmella Haynes 1 collaboration

Neel S Joshi 1 collaboration

April M Kloxin 1 collaboration

Paul H J Kouwer 1 collaboration

Jeetain Mittal 1 collaboration

Leonardo Morsut 1 collaboration

Vincent Noireaux 1 collaboration

Sapun Parekh 1 collaboration

Rebecca Schulman 1 collaboration

Sindy K Y Tang 1 collaboration

Megan T Valentine 1 collaboration

Sebastián L Vega 1 collaboration

Wilfried Weber 1 collaboration

Ovijit Chaudhuri 1 collaboration

Purbasha Nandi 1 collaboration

Dewight Williams 1 collaboration

Po-Lin Chiu 1 collaboration

Kyle Riker 1 collaboration

Rong Zheng 1 collaboration

Zijian Wan 1 collaboration

Xiaoyan Zhou 1 collaboration

Ryan M Porter 1 collaboration

Yize Li 1 collaboration

Shaopeng Wang 1 collaboration

Bryan Ugaz 1 collaboration

Tunjung Mahatmanto 1 collaboration

Isyatul Azizah 1 collaboration

Ankit Gangrade 1 collaboration

Dhiraj Bhatia 1 collaboration

Ilyssa Crawford 1 collaboration

Briana I Martinez 1 collaboration

Gergey Alzaem Mousa 1 collaboration

Kiera Fleck 1 collaboration

Chris W Diehnelt 1 collaboration

Sarah E Stabenfeldt 1 collaboration

Lei Zou 1 collaboration

Matthew J Webber 1 collaboration

T Teng 1 collaboration

J Bernal-Chanchavac 1 collaboration

N Stephanopoulos 1 collaboration

C E Castro 1 collaboration

Lu Yu 1 collaboration

Daria Bukharina 1 collaboration

Katherine Cauffiel 1 collaboration

Laura Mae Killingsworth 1 collaboration

Justin A Brackenridge 1 collaboration

Valeriia Poliukhova 1 collaboration

Minkyu Kim 1 collaboration

Justin Brower 1 collaboration

Vladimir V Tsukruk 1 collaboration