Nicolas Levoin

Affiliations

Bioprojet Biotech, 4 rue du Chesnay Beauregard, 35760 Saint-Grégoire, France. Electronic address: n.levoin@bioprojet.com.

Publications (11)

Synthesis of peptidomimetics and chemo-biological tools for CD95/PLCγ1 interaction analysis.

Bioorganic & medicinal chemistry letters

Avec: Ha Thanh Nguyen , Jean-Philippe Guégan , Amanda Poissonnier , Florence Jouan , Daniel Best , Pierre van de Weghe , Pierre Vacher , Nicolas Levoin , Patrick Legembre , Mickael Jean

CD95L concatemers highlight different stoichiometries of CD95-mediated apoptotic and nonapoptotic pathways.

European journal of immunology

Avec: Eden Lebrault , Christelle Oblet , Keerthi Kurma , Nicolas Levoin , Robin Jeannet , Mickael Jean , Pierre Vacher , Patrick Legembre

Structural revision of the Mcl-1 inhibitor MIM1: synthesis and biological studies on ovarian cancer cells with evaluation of designed analogues.

Organic & biomolecular chemistry

Avec: Hippolyte Paysant , Siham Hedir , Frédéric Justaud , Louis Bastien Weiswald , Assaad Nasr El Dine , Ali Soulieman , Ali Hachem , Nicolas Elie , Emilie Brotin , Christophe Denoyelle , Jérôme Bignon , Fanny Roussi , Marie Jouanne , Olivier Tasseau , Thierry Roisnel , Anne Sophie Voisin-Chiret , René Grée , Nicolas Levoin , Laurent Poulain

Structure Activity Relationship Studies around

Molecules (Basel, Switzerland)

Avec: Dabbugoddu Brahmaiah , Anagani Kanaka Durga Bhavani , Pasula Aparna , Nangunoori Sampath Kumar , Hélène Solhi , Rémy Le Guevel , Blandine Baratte , Thomas Robert , Sandrine Ruchaud , Stéphane Bach , Surender Singh Jadav , Chada Raji Reddy , Paul Mosset , Nicolas Gouault , Nicolas Levoin , René Grée

Probing the side chain tolerance for inhibitors of the CD95/PLCγ1 interaction.

Bioorganic & medicinal chemistry letters

Avec: Ha Thanh Nguyen , Jean-Philippe Guégan , Daniel Best , Pierre van de Weghe , Nicolas Levoin , Patrick Legembre , Mickael Jean

Discovery of DB18, a potent inhibitor of CLK kinases with a high selectivity against DYRK1A kinase.

Bioorganic & medicinal chemistry

Avec: Dabbugoddu Brahmaiah , Anagani Kanaka Durga Bhavani , Pasula Aparna , Nangunoori Sampath Kumar , Hélène Solhi , Rémy Le Guevel , Blandine Baratte , Sandrine Ruchaud , Stéphane Bach , Surender Singh Jadav , Chada Raji Reddy , Thierry Roisnel , Paul Mosset , Nicolas Levoin , René Grée

MMP7 cleavage of amino-terminal CD95 death receptor switches signaling toward non-apoptotic pathways.

Cell death & disease

Avec: Shoji F Kenji , Keerthi Kurma , Brigitte Collet , Christelle Oblet , Laure Debure , Carmelo Di Primo , Laëtitia Minder , Franck Vérité , Yannic Danger , Mickael Jean , Aubin Penna , Nicolas Levoin , Patrick Legembre

CD95 Structure, Aggregation and Cell Signaling.

Frontiers in cell and developmental biology

Avec: Nicolas Levoin , Mickael Jean , Patrick Legembre

Targeting PUMA/Bcl-xL interaction by new specific compounds to unleash apoptotic process in cancer cells.

European journal of medicinal chemistry

Avec: Appala Venkata Ramana Murthy , Vennu Narendar , Nangunoori Sampath Kumar , Pasula Aparna , Anagani Kanaka Durga Bhavani , Fabien Gautier , Sophie Barillé-Nion , Philippe Juin , Paul Mosset , René Grée , Nicolas Levoin

Synthesis and biological studies of new piperidino-1,2,3-triazole hybrids with 3-aryl isoxazole side chains.

Bioorganic & medicinal chemistry letters

Avec: Appala Venkata Ramana Murthy , Vennu Narendar , Nangunoori Sampath Kumar , Pasula Aparna , Anagani Kanaka Durga Bhavani , Hélène Solhi , Rémy Le Guevel , Julie Roul , Fabien Gautier , Philippe Juin , Chada Raji Reddy , Paul Mosset , Nicolas Levoin , René Grée

Discovery of potent dual ligands for dopamine D4 and σ1 receptors.

Bioorganic & medicinal chemistry

Avec: Nicolas Levoin , Appala Venkata Ramana Murthy , Vennu Narendar , Nangunoori Sampath Kumar , Pasula Aparna , Anagani Kanaka Durga Bhavani , Chada Raji Reddy , Paul Mosset , René Grée

Réseau de co-auteurs

René Grée 6 collaborations

Patrick Legembre 5 collaborations

Mickael Jean 5 collaborations

Anagani Kanaka Durga Bhavani 5 collaborations

Pasula Aparna 5 collaborations

Nangunoori Sampath Kumar 5 collaborations

Paul Mosset 5 collaborations

Chada Raji Reddy 4 collaborations

Hélène Solhi 3 collaborations

Rémy Le Guevel 3 collaborations

Appala Venkata Ramana Murthy 3 collaborations

Vennu Narendar 3 collaborations

Ha Thanh Nguyen 2 collaborations

Jean-Philippe Guégan 2 collaborations

Daniel Best 2 collaborations

Pierre van de Weghe 2 collaborations

Pierre Vacher 2 collaborations

Christelle Oblet 2 collaborations

Keerthi Kurma 2 collaborations

Thierry Roisnel 2 collaborations

Dabbugoddu Brahmaiah 2 collaborations

Blandine Baratte 2 collaborations

Sandrine Ruchaud 2 collaborations

Stéphane Bach 2 collaborations

Surender Singh Jadav 2 collaborations

Fabien Gautier 2 collaborations

Philippe Juin 2 collaborations

Amanda Poissonnier 1 collaboration

Florence Jouan 1 collaboration

Eden Lebrault 1 collaboration

Robin Jeannet 1 collaboration

Hippolyte Paysant 1 collaboration

Siham Hedir 1 collaboration

Frédéric Justaud 1 collaboration

Louis Bastien Weiswald 1 collaboration

Assaad Nasr El Dine 1 collaboration

Ali Soulieman 1 collaboration

Ali Hachem 1 collaboration

Nicolas Elie 1 collaboration

Emilie Brotin 1 collaboration

Christophe Denoyelle 1 collaboration

Jérôme Bignon 1 collaboration

Fanny Roussi 1 collaboration

Marie Jouanne 1 collaboration

Olivier Tasseau 1 collaboration

Anne Sophie Voisin-Chiret 1 collaboration

Laurent Poulain 1 collaboration

Thomas Robert 1 collaboration

Nicolas Gouault 1 collaboration

Shoji F Kenji 1 collaboration

Brigitte Collet 1 collaboration

Laure Debure 1 collaboration

Carmelo Di Primo 1 collaboration

Laëtitia Minder 1 collaboration

Franck Vérité 1 collaboration

Yannic Danger 1 collaboration

Aubin Penna 1 collaboration

Sophie Barillé-Nion 1 collaboration

Julie Roul 1 collaboration