Nicolas Winssinger

Affiliations

Department of Organic Chemistry, NCCR Chemical Biology, Faculty of Science, University of Geneva, 30 quai Ernest Ansermet, 1205 Geneva, Switzerland.

ORCID: 0000-0003-1636-7766

Publications (47)

Sense-and-Release Logic-Gated Molecular Network Responding to Dimeric Cell Surface Proteins.

Journal of the American Chemical Society

Avec: Simona Angerani , Nicolas Winssinger

Luciferase-Induced Photouncaging: Bioluminolysis.

Angewandte Chemie (International ed. in English)

Avec: Dalu Chang , Eric Lindberg , Suihan Feng , Simona Angerani , Howard Riezman , Nicolas Winssinger

Probing for Thiol-Mediated Uptake into Bacteria.

Chembiochem : a European journal of chemical biology

Avec: Quentin Laurent , Mathéo Berthet , Yangyang Cheng , Naomi Sakai , Sofia Barluenga , Nicolas Winssinger , Stefan Matile

A mating mechanism to generate diversity for the Darwinian selection of DNA-encoded synthetic molecules.

Nature chemistry

Avec: Balayeshwanth R Vummidi , Lluc Farrera-Soler , Jean-Pierre Daguer , Millicent Dockerill , Sofia Barluenga , Nicolas Winssinger

PNA-Encoded Synthesis (PES) and DNA Display of Small Molecule Libraries.

Methods in molecular biology (Clifton, N.J.)

Avec: Jacques Saarbach , Sofia Barluenga , Nicolas Winssinger

Withaferin A, a polyfunctional pharmacophore that includes covalent engagement of IPO5, is an inhibitor of influenza A replication.

Bioorganic & medicinal chemistry

Avec: Remi Patouret , Sofia Barluenga , Nicolas Winssinger

Pseudo-Complementary G:C Base Pair for Mixed Sequence dsDNA Invasion and Its Applications in Diagnostics (SARS-CoV-2 Detection).

JACS Au

Avec: Miguel López-Tena , Lluc Farrera-Soler , Sofia Barluenga , Nicolas Winssinger

Lysosome-targeted photoactivation reveals local sphingosine metabolism signatures.

Chemical science

Avec: Suihan Feng , Takeshi Harayama , Dalu Chang , J Thomas Hannich , Nicolas Winssinger , Howard Riezman

Sphingolipids and membrane targets for therapeutics.

Current opinion in chemical biology

Avec: Robbie Loewith , Howard Riezman , Nicolas Winssinger

Combining recombinase polymerase amplification and DNA-templated reaction for SARS-CoV-2 sensing with dual fluorescence and lateral flow assay output.

Biopolymers

Avec: Lluc Farrera-Soler , Arthur Gonse , Ki Tae Kim , Sofia Barluenga , Nicolas Winssinger

Experimental Identification of Immuno- dominant B-cell Epitopes from SARS-CoV-2.

Chimia

Avec: Lluc Farrera-Soler , Jean-Pierre Daguer , Sofia Barluenga , Nicolas Winssinger

Biosupramolecular Systems: Integrating Cues into Responses.

Journal of the American Chemical Society

Avec: Emma E Watson , Simona Angerani , Pramod M Sabale , Nicolas Winssinger

Optochemical Control of Therapeutic Agents through Photocatalyzed Isomerization.

Angewandte Chemie (International ed. in English)

Avec: Emma E Watson , Francesco Russo , Dimitri Moreau , Nicolas Winssinger

A minimal hybridization chain reaction (HCR) system using peptide nucleic acids.

Chemical science

Avec: Ki Tae Kim , Simona Angerani , Nicolas Winssinger

Translation of Deoxyribonucleic Acid into Synthetic Alpha Helical Peptides for Darwinian Evolution.

JACS Au

Avec: Millicent Dockerill , Pramod M Sabale , Francesco Russo , Sofia Barluenga , Nicolas Winssinger

PNA-Based Dynamic Combinatorial Libraries (PDCL) and screening of lectins.

Bioorganic & medicinal chemistry

Avec: Lluc Farrera-Soler , Jean-Pierre Daguer , Patrick Raunft , Sofia Barluenga , Anne Imberty , Nicolas Winssinger

Small-Molecule Modulators of the ATPase VCP/p97 Affect Specific p97 Cellular Functions.

ACS chemical biology

Avec: Ainoa Figuerola-Conchas , Jacques Saarbach , Jean-Pierre Daguer , Adeline Cieren , Sofia Barluenga , Nicolas Winssinger , Monica Gotta

Kinesin-1 activity recorded in living cells with a precipitating dye.

Nature communications

Avec: Simona Angerani , Eric Lindberg , Nikolai Klena , Christopher K E Bleck , Charlotte Aumeier , Nicolas Winssinger

Total Syntheses of Paraconic Acids and 1,10-

Organic letters

Avec: Weilong Liu , Zhimei Yu , Nicolas Winssinger

Oligonucleotide Phosphorothioates Enter Cells by Thiol-Mediated Uptake.

Angewandte Chemie (International ed. in English)

Avec: Quentin Laurent , Rémi Martinent , Dimitri Moreau , Nicolas Winssinger , Naomi Sakai , Stefan Matile

Supernatural: Artificial Nucleobases and Backbones to Program Hybridization-Based Assemblies and Circuits.

Bioconjugate chemistry

Avec: Miguel López-Tena , Si-Kai Chen , Nicolas Winssinger

Two-Helix Supramolecular Proteomimetic Binders Assembled via PNA-Assisted Disulfide Crosslinking.

Chembiochem : a European journal of chemical biology

Avec: Mateusz Imiołek , Nicolas Winssinger

Bright Red Bioluminescence from Semisynthetic NanoLuc (sNLuc).

ACS chemical biology

Avec: Francesco Russo , Beatrice Civili , Nicolas Winssinger

PTPRZ1-targeting RNA CAR T cells exert antigen-specific and bystander antitumor activity in glioblastoma.

Cancer immunology research

Avec: Darel Martínez Bedoya , Eliana Marinari , Suzel Davanture , Luis Castillo Cantero , Sarah Erraiss , Millicent Dockerill , Sofia Barluenga , Nicolas Winssinger , Karl Schaller , Philippe Bijlenga , Shahan Momjian , Christel Voize , Stéphanie R Tissot , Lana E Kandalaft , Philippe Hammel , Pierre Cosson , Paul R Walker , Valérie Dutoit , Denis Migliorini

Luciferase Controlled Protein Interactions.

Journal of the American Chemical Society

Avec: Dalu Chang , Suihan Feng , Vladimir Girik , Howard Riezman , Nicolas Winssinger

Coupling of DNA Circuit and Templated Reactions for Quadratic Amplification and Release of Functional Molecules.

Journal of the American Chemical Society

Avec: Ki Tae Kim , Simona Angerani , Dalu Chang , Nicolas Winssinger

Peptide nucleic acid (PNA) and its applications in chemical biology, diagnostics, and therapeutics.

Current opinion in chemical biology

Avec: Jacques Saarbach , Pramod M Sabale , Nicolas Winssinger

Kilian Muñiz (1970-2020).

Angewandte Chemie (International ed. in English)

Avec: Jan Streuff , Antonio M Echavarren , José Manuel González , Martin Oestreich , Andreas Gansäuer , Sofia Barluenga , Nicolas Winssinger

Smartphone DNA or RNA Sensing Using Semisynthetic Luciferase-Based Logic Device.

ACS sensors

Avec: Dalu Chang , Ki Tae Kim , Eric Lindberg , Nicolas Winssinger

Identification of immunodominant linear epitopes from SARS-CoV-2 patient plasma.

PloS one

Avec: Lluc Farrera-Soler , Jean-Pierre Daguer , Sofia Barluenga , Oscar Vadas , Patrick Cohen , Sabrina Pagano , Sabine Yerly , Laurent Kaiser , Nicolas Vuilleumier , Nicolas Winssinger

Suprastapled Peptides: Hybridization-Enhanced Peptide Ligation and Enforced α-Helical Conformation for Affinity Selection of Combinatorial Libraries.

Journal of the American Chemical Society

Avec: Pramod M Sabale , Mateusz Imiołek , Pierre Raia , Sofia Barluenga , Nicolas Winssinger

Impact of charges on the hybridization kinetics and thermal stability of PNA duplexes.

Organic & biomolecular chemistry

Avec: Miguel López-Tena , Nicolas Winssinger

Development of supramolecular anticoagulants with on-demand reversibility.

Nature biotechnology

Avec: Millicent Dockerill , Daniel J Ford , Simona Angerani , Imala Alwis , Luke J Dowman , Jorge Ripoll-Rozada , Rhyll E Smythe , Joanna S T Liu , Pedro José Barbosa Pereira , Shaun P Jackson , Richard J Payne , Nicolas Winssinger

Visible Light Photoredox Catalysis Using Ruthenium Complexes in Chemical Biology.

Chemistry (Weinheim an der Bergstrasse, Germany)

Avec: Simona Angerani , Nicolas Winssinger

Turn On of a Ruthenium(II) Photocatalyst by DNA-Templated Ligation.

Chemistry (Weinheim an der Bergstrasse, Germany)

Avec: Marcello Anzola , Nicolas Winssinger

Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9.

Molecular & cellular proteomics : MCP

Avec: Michael Plank , Mariya Perepelkina , Markus Müller , Stefania Vaga , Xiaoming Zou , Clélia Bourgoint , Marina Berti , Jacques Saarbach , Steven Haesendonckx , Nicolas Winssinger , Ruedi Aebersold , Robbie Loewith

Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane Networks.

Journal of the American Chemical Society

Avec: Javier López-Andarias , Jacques Saarbach , Dimitri Moreau , Yangyang Cheng , Emmanuel Derivery , Quentin Laurent , Marcos González-Gaitán , Nicolas Winssinger , Naomi Sakai , Stefan Matile

Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides.

ACS central science

Avec: Weilong Liu , Rémi Patouret , Sofia Barluenga , Michael Plank , Robbie Loewith , Nicolas Winssinger

Inhibition of HSP90 as a Strategy to Radiosensitize Glioblastoma: Targeting the DNA Damage Response and Beyond.

Frontiers in oncology

Avec: Michael Orth , Valerie Albrecht , Karin Seidl , Linda Kinzel , Kristian Unger , Julia Hess , Lisa Kreutzer , Na Sun , Benjamin Stegen , Alexander Nieto , Jessica Maas , Nicolas Winssinger , Anna A Friedl , Axel K Walch , Claus Belka , Horst Zitzelsberger , Maximilian Niyazi , Kirsten Lauber

Priming of Anti-tumor Immune Mechanisms by Radiotherapy Is Augmented by Inhibition of Heat Shock Protein 90.

Frontiers in oncology

Avec: Anne Ernst , Roman Hennel , Julia Krombach , Heidi Kapfhammer , Nikko Brix , Gabriele Zuchtriegel , Bernd Uhl , Christoph A Reichel , Benjamin Frey , Udo S Gaipl , Nicolas Winssinger , Senji Shirasawa , Takehiko Sasazuki , Markus Sperandio , Claus Belka , Kirsten Lauber

Enhanced SNP-sensing using DNA-templated reactions through confined hybridization of minimal substrates (CHOMS).

Chemical science

Avec: Ki Tae Kim , Nicolas Winssinger

Dual Bcl-X

Bioorganic & medicinal chemistry

Avec: Jean-Pierre Daguer , Arthur Gonse , Yevhenii Shchukin , Lluc Farrera-Soler , Sofia Barluenga , Nicolas Winssinger

SARS-CoV-2 infection as a trigger of humoral response against apolipoprotein A-1.

European journal of clinical investigation

Avec: Sabrina Pagano , Sabine Yerly , Benjamin Meyer , Catherine Juillard , Noémie Suh , Christophe Le Terrier , Jean-Pierre Daguer , Lluc Farrera-Soler , Sofia Barluenga , Giovanni Piumatti , Oliver Hartley , Barbara Lemaitre , Christiane S Eberhardt , Claire-Anne Siegrist , Isabella Eckerle , Silvia Stringhini , Idris Guessous , Laurent Kaiser , Jerome Pugin , Nicolas Winssinger , Nicolas Vuilleumier

Flipper Probes for the Community.

Chimia

Avec: Lea Assies , José García-Calvo , Francesca Piazzolla , Samantha Sanchez , Takehiro Kato , Luc Reymond , Antoine Goujon , Adai Colom , Javier López-Andarias , Karolína Straková , Dora Mahecic , Vincent Mercier , Margot Riggi , Noemi Jiménez-Rojo , Chloé Roffay , Giuseppe Licari , Maria Tsemperouli , Frederik Neuhaus , Alexandre Fürstenberg , Eric Vauthey , Sascha Hoogendoorn , Marcos Gonzalez-Gaitan , Andreas Zumbuehl , Kaori Sugihara , Jean Gruenberg , Howard Riezman , Robbie Loewith , Suliana Manley , Aurelien Roux , Nicolas Winssinger , Naomi Sakai , Stefan Pitsch , Stefan Matile

Biosupramolecular networks: Taking inspiration from nature to create powerful synthetic platforms.

Current opinion in chemical biology

Avec: Emma E Watson , Nicolas Winssinger

Synthesis of Protein-Oligonucleotide Conjugates.

Biomolecules

Avec: Emma E Watson , Nicolas Winssinger

DNA-Encoded Libraries: Towards Harnessing their Full Power with Darwinian Evolution.

Angewandte Chemie (International ed. in English)

Avec: Millicent Dockerill , Nicolas Winssinger

Réseau de co-auteurs

Sofia Barluenga 17 collaborations

Simona Angerani 8 collaborations

Lluc Farrera-Soler 8 collaborations

Jean-Pierre Daguer 7 collaborations

Dalu Chang 5 collaborations

Howard Riezman 5 collaborations

Millicent Dockerill 5 collaborations

Jacques Saarbach 5 collaborations

Ki Tae Kim 5 collaborations

Naomi Sakai 4 collaborations

Stefan Matile 4 collaborations

Robbie Loewith 4 collaborations

Emma E Watson 4 collaborations

Pramod M Sabale 4 collaborations

Eric Lindberg 3 collaborations

Suihan Feng 3 collaborations

Quentin Laurent 3 collaborations

Miguel López-Tena 3 collaborations

Francesco Russo 3 collaborations

Dimitri Moreau 3 collaborations

Yangyang Cheng 2 collaborations

Arthur Gonse 2 collaborations

Weilong Liu 2 collaborations

Mateusz Imiołek 2 collaborations

Sabrina Pagano 2 collaborations

Sabine Yerly 2 collaborations

Laurent Kaiser 2 collaborations

Nicolas Vuilleumier 2 collaborations

Michael Plank 2 collaborations

Javier López-Andarias 2 collaborations

Claus Belka 2 collaborations

Kirsten Lauber 2 collaborations

Mathéo Berthet 1 collaboration

Balayeshwanth R Vummidi 1 collaboration

Remi Patouret 1 collaboration

Takeshi Harayama 1 collaboration

J Thomas Hannich 1 collaboration

Patrick Raunft 1 collaboration

Anne Imberty 1 collaboration

Ainoa Figuerola-Conchas 1 collaboration

Adeline Cieren 1 collaboration

Monica Gotta 1 collaboration

Nikolai Klena 1 collaboration

Christopher K E Bleck 1 collaboration

Charlotte Aumeier 1 collaboration

Zhimei Yu 1 collaboration

Rémi Martinent 1 collaboration

Si-Kai Chen 1 collaboration

Beatrice Civili 1 collaboration

Darel Martínez Bedoya 1 collaboration

Eliana Marinari 1 collaboration

Suzel Davanture 1 collaboration

Luis Castillo Cantero 1 collaboration

Sarah Erraiss 1 collaboration

Karl Schaller 1 collaboration

Philippe Bijlenga 1 collaboration

Shahan Momjian 1 collaboration

Christel Voize 1 collaboration

Stéphanie R Tissot 1 collaboration

Lana E Kandalaft 1 collaboration

Philippe Hammel 1 collaboration

Pierre Cosson 1 collaboration

Paul R Walker 1 collaboration

Valérie Dutoit 1 collaboration

Denis Migliorini 1 collaboration

Vladimir Girik 1 collaboration

Jan Streuff 1 collaboration

Antonio M Echavarren 1 collaboration

José Manuel González 1 collaboration

Martin Oestreich 1 collaboration

Andreas Gansäuer 1 collaboration

Oscar Vadas 1 collaboration

Patrick Cohen 1 collaboration

Pierre Raia 1 collaboration

Daniel J Ford 1 collaboration

Imala Alwis 1 collaboration

Luke J Dowman 1 collaboration

Jorge Ripoll-Rozada 1 collaboration

Rhyll E Smythe 1 collaboration

Joanna S T Liu 1 collaboration

Pedro José Barbosa Pereira 1 collaboration

Shaun P Jackson 1 collaboration

Richard J Payne 1 collaboration

Marcello Anzola 1 collaboration

Mariya Perepelkina 1 collaboration

Markus Müller 1 collaboration

Stefania Vaga 1 collaboration

Xiaoming Zou 1 collaboration

Clélia Bourgoint 1 collaboration

Marina Berti 1 collaboration

Steven Haesendonckx 1 collaboration

Ruedi Aebersold 1 collaboration

Emmanuel Derivery 1 collaboration

Marcos González-Gaitán 1 collaboration

Rémi Patouret 1 collaboration

Michael Orth 1 collaboration

Valerie Albrecht 1 collaboration

Karin Seidl 1 collaboration

Linda Kinzel 1 collaboration

Kristian Unger 1 collaboration

Julia Hess 1 collaboration

Lisa Kreutzer 1 collaboration

Na Sun 1 collaboration

Benjamin Stegen 1 collaboration

Alexander Nieto 1 collaboration

Jessica Maas 1 collaboration

Anna A Friedl 1 collaboration

Axel K Walch 1 collaboration

Horst Zitzelsberger 1 collaboration

Maximilian Niyazi 1 collaboration

Anne Ernst 1 collaboration

Roman Hennel 1 collaboration

Julia Krombach 1 collaboration

Heidi Kapfhammer 1 collaboration

Nikko Brix 1 collaboration

Gabriele Zuchtriegel 1 collaboration

Bernd Uhl 1 collaboration

Christoph A Reichel 1 collaboration

Benjamin Frey 1 collaboration

Udo S Gaipl 1 collaboration

Senji Shirasawa 1 collaboration

Takehiko Sasazuki 1 collaboration

Markus Sperandio 1 collaboration

Yevhenii Shchukin 1 collaboration

Benjamin Meyer 1 collaboration

Catherine Juillard 1 collaboration

Noémie Suh 1 collaboration

Christophe Le Terrier 1 collaboration

Giovanni Piumatti 1 collaboration

Oliver Hartley 1 collaboration

Barbara Lemaitre 1 collaboration

Christiane S Eberhardt 1 collaboration

Claire-Anne Siegrist 1 collaboration

Isabella Eckerle 1 collaboration

Silvia Stringhini 1 collaboration

Idris Guessous 1 collaboration

Jerome Pugin 1 collaboration

Lea Assies 1 collaboration

José García-Calvo 1 collaboration

Francesca Piazzolla 1 collaboration

Samantha Sanchez 1 collaboration

Takehiro Kato 1 collaboration

Luc Reymond 1 collaboration

Antoine Goujon 1 collaboration

Adai Colom 1 collaboration

Karolína Straková 1 collaboration

Dora Mahecic 1 collaboration

Vincent Mercier 1 collaboration

Margot Riggi 1 collaboration

Noemi Jiménez-Rojo 1 collaboration

Chloé Roffay 1 collaboration

Giuseppe Licari 1 collaboration

Maria Tsemperouli 1 collaboration

Frederik Neuhaus 1 collaboration

Alexandre Fürstenberg 1 collaboration

Eric Vauthey 1 collaboration

Sascha Hoogendoorn 1 collaboration

Marcos Gonzalez-Gaitan 1 collaboration

Andreas Zumbuehl 1 collaboration

Kaori Sugihara 1 collaboration

Jean Gruenberg 1 collaboration

Suliana Manley 1 collaboration

Aurelien Roux 1 collaboration

Stefan Pitsch 1 collaboration