Nikolas Gunkel

Affiliations

Cancer Drug Development Group, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
German Cancer Consortium (DKTK), 69120, Heidelberg, Germany.

Publications (7)

Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors.

ChemMedChem

Avec: Michael Morgen , Raphael R Steimbach , Magalie Géraldy , Lars Hellweg , Peter Sehr , Johannes Ridinger , Olaf Witt , Ina Oehme , Corey J Herbst-Gervasoni , Jeremy D Osko , Nicholas J Porter , David W Christianson , Nikolas Gunkel , Aubry K Miller

Synthesis and Structure-Activity Relationships of N-(4-Benzamidino)-Oxazolidinones: Potent and Selective Inhibitors of Kallikrein-Related Peptidase 6.

ChemMedChem

Avec: Elena De Vita , Niels Smits , Helma van den Hurk , Elizabeth M Beck , Joanne Hewitt , Gemma Baillie , Emily Russell , Andrew Pannifer , Véronique Hamon , Angus Morrison , Stuart P McElroy , Philip Jones , Natalia A Ignatenko , Nikolas Gunkel , Aubry K Miller

Inclusion Complexes of Gold(I)-Dithiocarbamates with β-Cyclodextrin: A Journey from Drug Repurposing towards Drug Discovery.

Chemistry (Weinheim an der Bergstrasse, Germany)

Avec: Michael Morgen , Piotr Fabrowski , Eberhard Amtmann , Nikolas Gunkel , Aubry K Miller

Low level of antioxidant capacity biomarkers but not target overexpression predicts vulnerability to ROS-inducing drugs.

Redox biology

Avec: Jana Samarin , Piotr Fabrowski , Roman Kurilov , Hana Nuskova , Johanna Hummel-Eisenbeiss , Hannelore Pink , Nan Li , Vivienn Weru , Hamed Alborzinia , Umut Yildiz , Laura Grob , Minerva Taubert , Marie Czech , Michael Morgen , Christina Brandstädter , Katja Becker , Lianghao Mao , Ashok Kumar Jayavelu , Angela Goncalves , Ulrike Uhrig , Jeanette Seiler , Yanhong Lyu , Sven Diederichs , Ursula Klingmüller , Martina Muckenthaler , Annette Kopp-Schneider , Aurelio Teleman , Aubry K Miller , Nikolas Gunkel

Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated.

Journal of medicinal chemistry

Avec: Magalie Géraldy , Michael Morgen , Peter Sehr , Raphael R Steimbach , Davide Moi , Johannes Ridinger , Ina Oehme , Olaf Witt , Mona Malz , Mauro S Nogueira , Oliver Koch , Nikolas Gunkel , Aubry K Miller

First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement.

Chembiochem : a European journal of chemical biology

Avec: Daniel Herp , Johannes Ridinger , Dina Robaa , Stephen A Shinsky , Karin Schmidtkunz , Talha Z Yesiloglu , Theresa Bayer , Raphael R Steimbach , Corey J Herbst-Gervasoni , Annika Merz , Christophe Romier , Peter Sehr , Nikolas Gunkel , Aubry K Miller , David W Christianson , Ina Oehme , Wolfgang Sippl , Manfred Jung

Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout.

Journal of the American Chemical Society

Avec: Raphael R Steimbach , Corey J Herbst-Gervasoni , Severin Lechner , Tracy Murray Stewart , Glynis Klinke , Johannes Ridinger , Magalie N E Géraldy , Gergely Tihanyi , Jackson R Foley , Ulrike Uhrig , Bernhard Kuster , Gernot Poschet , Robert A Casero , Guillaume Médard , Ina Oehme , David W Christianson , Nikolas Gunkel , Aubry K Miller

Réseau de co-auteurs

Aubry K Miller 7 collaborations

Michael Morgen 4 collaborations

Raphael R Steimbach 4 collaborations

Johannes Ridinger 4 collaborations

Ina Oehme 4 collaborations

Peter Sehr 3 collaborations

Corey J Herbst-Gervasoni 3 collaborations

David W Christianson 3 collaborations

Magalie Géraldy 2 collaborations

Olaf Witt 2 collaborations

Piotr Fabrowski 2 collaborations

Ulrike Uhrig 2 collaborations

Lars Hellweg 1 collaboration

Jeremy D Osko 1 collaboration

Nicholas J Porter 1 collaboration

Elena De Vita 1 collaboration

Niels Smits 1 collaboration

Helma van den Hurk 1 collaboration

Elizabeth M Beck 1 collaboration

Joanne Hewitt 1 collaboration

Gemma Baillie 1 collaboration

Emily Russell 1 collaboration

Andrew Pannifer 1 collaboration

Véronique Hamon 1 collaboration

Angus Morrison 1 collaboration

Stuart P McElroy 1 collaboration

Philip Jones 1 collaboration

Natalia A Ignatenko 1 collaboration

Eberhard Amtmann 1 collaboration

Jana Samarin 1 collaboration

Roman Kurilov 1 collaboration

Hana Nuskova 1 collaboration

Johanna Hummel-Eisenbeiss 1 collaboration

Hannelore Pink 1 collaboration

Nan Li 1 collaboration

Vivienn Weru 1 collaboration

Hamed Alborzinia 1 collaboration

Umut Yildiz 1 collaboration

Laura Grob 1 collaboration

Minerva Taubert 1 collaboration

Marie Czech 1 collaboration

Christina Brandstädter 1 collaboration

Katja Becker 1 collaboration

Lianghao Mao 1 collaboration

Ashok Kumar Jayavelu 1 collaboration

Angela Goncalves 1 collaboration

Jeanette Seiler 1 collaboration

Yanhong Lyu 1 collaboration

Sven Diederichs 1 collaboration

Ursula Klingmüller 1 collaboration

Martina Muckenthaler 1 collaboration

Annette Kopp-Schneider 1 collaboration

Aurelio Teleman 1 collaboration

Davide Moi 1 collaboration

Mona Malz 1 collaboration

Mauro S Nogueira 1 collaboration

Oliver Koch 1 collaboration

Daniel Herp 1 collaboration

Dina Robaa 1 collaboration

Stephen A Shinsky 1 collaboration

Karin Schmidtkunz 1 collaboration

Talha Z Yesiloglu 1 collaboration

Theresa Bayer 1 collaboration

Annika Merz 1 collaboration

Christophe Romier 1 collaboration

Wolfgang Sippl 1 collaboration

Manfred Jung 1 collaboration

Severin Lechner 1 collaboration

Tracy Murray Stewart 1 collaboration

Glynis Klinke 1 collaboration

Magalie N E Géraldy 1 collaboration

Gergely Tihanyi 1 collaboration

Jackson R Foley 1 collaboration

Bernhard Kuster 1 collaboration

Gernot Poschet 1 collaboration

Robert A Casero 1 collaboration

Guillaume Médard 1 collaboration