Rob Layfield

Affiliations

School of Life Sciences, University of Nottingham Medical School, Nottingham, UK.

Publications (16)

An FTLD-associated SQSTM1 variant impacts Nrf2 and NF-κB signalling and is associated with reduced phosphorylation of p62.

Molecular and cellular neurosciences

Avec: A Foster , D Scott , R Layfield , S L Rea

Site-Selective Modification of Peptides and Proteins via Interception of Free-Radical-Mediated Dechalcogenation.

Angewandte Chemie (International ed. in English)

Avec: Rhys C Griffiths , Frances R Smith , Jed E Long , Huw E L Williams , Robert Layfield , Nicholas J Mitchell

Modification of small ubiquitin-related modifier 2 (SUMO2) by phosphoubiquitin in HEK293T cells.

Proteomics

Avec: Julius T Dongdem , Simon P Dawson , Robert Layfield

An ALS-associated variant of the autophagy receptor SQSTM1/p62 reprograms binding selectivity toward the autophagy-related hATG8 proteins.

The Journal of biological chemistry

Avec: Andrew Brennan , Robert Layfield , Jed Long , Huw E L Williams , Neil J Oldham , Daniel Scott , Mark S Searle

Preservation of whole antibodies within ancient teeth.

iScience

Avec: Barry Shaw , Thomas McDonnell , Elizabeth Radley , Brian Thomas , Lynn Smith , Carol A L Davenport , Silvia Gonzalez , Anisur Rahman , Rob Layfield

Developing Porous Ortho- and Pyrophosphate-Containing Glass Microspheres; Structural and Cytocompatibility Characterisation.

Bioengineering (Basel, Switzerland)

Avec: Ben Milborne , Lauren Murrell , Ian Cardillo-Zallo , Jeremy Titman , Louise Briggs , Colin Scotchford , Alexander Thompson , Robert Layfield , Ifty Ahmed

A Technology-Enhanced Intervention for Violence and Substance Use Prevention Among Young Black Men: Protocol for Adaptation and Pilot Testing.

JMIR research protocols

Avec: Chuka Emezue , Niranjan S Karnik , Blaine Reeder , Michael Schoeny , Rickey Layfield , Amie Zarling , Wrenetha Julion

Antibody-based sex determination of human skeletal remains.

iScience

Avec: Barry Shaw , Sophie Foggin , Petter Hamilton-Stanley , Andy Barlow , Catriona Pickard , Linda Fibiger , Neil Oldham , Patrick Tighe , Lisette M Kootker , Sarah Schrader , Rob Layfield

ALS-associated TBK1 variant p.G175S is defective in phosphorylation of p62 and impacts TBK1-mediated signalling and TDP-43 autophagic degradation.

Molecular and cellular neurosciences

Avec: A D Foster , P Downing , E Figredo , N Polain , A Stott , R Layfield , S L Rea

De-ubiquitination of ELK-1 by USP17 potentiates mitogenic gene expression and cell proliferation.

Nucleic acids research

Avec: Charles Ducker , Leo Kam Yuen Chow , Janice Saxton , Jürgen Handwerger , Alexander McGregor , Thomas Strahl , Robert Layfield , Peter E Shaw

p62 overexpression induces TDP-43 cytoplasmic mislocalisation, aggregation and cleavage and neuronal death.

Scientific reports

Avec: A D Foster , L L Flynn , C Cluning , F Cheng , J M Davidson , A Lee , N Polain , R Mejzini , N Farrawell , J J Yerbury , R Layfield , P A Akkari , S L Rea

Comparative analysis of protein expression systems and PTM landscape in the study of transcription factor ELK-1.

Protein expression and purification

Avec: Charles Ducker , Manohar Ratnam , Peter E Shaw , Robert Layfield

Determination of hATG8 Binding Selectivity of AIM (Autophagy-Interacting Motif) Peptides Using Native Electrospray Ionization Mass Spectrometry.

Methods in molecular biology (Clifton, N.J.)

Avec: Andrew Brennan , Neil Oldham , Robert Layfield , Daniel Scott

Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Avec: Stuart H Ralston , Luis Corral-Gudino , Cyrus Cooper , Roger M Francis , William D Fraser , Luigi Gennari , Núria Guañabens , M Kassim Javaid , Robert Layfield , Terence W O'Neill , R Graham G Russell , Michael D Stone , Keith Simpson , Diana Wilkinson , Ruth Wills , M Carola Zillikens , Stephen P Tuck

Biological Significance of microRNA Biomarkers in ALS-Innocent Bystanders or Disease Culprits?

Frontiers in neurology

Avec: Sophie Foggin , Raquel Mesquita-Ribeiro , Federico Dajas-Bailador , Rob Layfield

Cysteine-Selective Modification of Peptides and Proteins via Desulfurative C-C Bond Formation.

Chemistry (Weinheim an der Bergstrasse, Germany)

Avec: Rhys C Griffiths , Frances R Smith , Diyuan Li , Jasmine Wyatt , David M Rogers , Jed E Long , Lola M L Cusin , Patrick J Tighe , Robert Layfield , Jonathan D Hirst , Manuel M Müller , Nicholas J Mitchell

Réseau de co-auteurs

Robert Layfield 9 collaborations

R Layfield 3 collaborations

S L Rea 3 collaborations

Rhys C Griffiths 2 collaborations

Frances R Smith 2 collaborations

Jed E Long 2 collaborations

Huw E L Williams 2 collaborations

Nicholas J Mitchell 2 collaborations

Andrew Brennan 2 collaborations

Daniel Scott 2 collaborations

Barry Shaw 2 collaborations

Sophie Foggin 2 collaborations

Neil Oldham 2 collaborations

A D Foster 2 collaborations

N Polain 2 collaborations

Charles Ducker 2 collaborations

Peter E Shaw 2 collaborations

A Foster 1 collaboration

D Scott 1 collaboration

Julius T Dongdem 1 collaboration

Simon P Dawson 1 collaboration

Jed Long 1 collaboration

Neil J Oldham 1 collaboration

Mark S Searle 1 collaboration

Thomas McDonnell 1 collaboration

Elizabeth Radley 1 collaboration

Brian Thomas 1 collaboration

Lynn Smith 1 collaboration

Carol A L Davenport 1 collaboration

Silvia Gonzalez 1 collaboration

Anisur Rahman 1 collaboration

Ben Milborne 1 collaboration

Lauren Murrell 1 collaboration

Ian Cardillo-Zallo 1 collaboration

Jeremy Titman 1 collaboration

Louise Briggs 1 collaboration

Colin Scotchford 1 collaboration

Alexander Thompson 1 collaboration

Ifty Ahmed 1 collaboration

Chuka Emezue 1 collaboration

Niranjan S Karnik 1 collaboration

Blaine Reeder 1 collaboration

Michael Schoeny 1 collaboration

Rickey Layfield 1 collaboration

Amie Zarling 1 collaboration

Wrenetha Julion 1 collaboration

Petter Hamilton-Stanley 1 collaboration

Andy Barlow 1 collaboration

Catriona Pickard 1 collaboration

Linda Fibiger 1 collaboration

Patrick Tighe 1 collaboration

Lisette M Kootker 1 collaboration

Sarah Schrader 1 collaboration

P Downing 1 collaboration

E Figredo 1 collaboration

A Stott 1 collaboration

Leo Kam Yuen Chow 1 collaboration

Janice Saxton 1 collaboration

Jürgen Handwerger 1 collaboration

Alexander McGregor 1 collaboration

Thomas Strahl 1 collaboration

L L Flynn 1 collaboration

C Cluning 1 collaboration

F Cheng 1 collaboration

J M Davidson 1 collaboration

A Lee 1 collaboration

R Mejzini 1 collaboration

N Farrawell 1 collaboration

J J Yerbury 1 collaboration

P A Akkari 1 collaboration

Manohar Ratnam 1 collaboration

Stuart H Ralston 1 collaboration

Luis Corral-Gudino 1 collaboration

Cyrus Cooper 1 collaboration

Roger M Francis 1 collaboration

William D Fraser 1 collaboration

Luigi Gennari 1 collaboration

Núria Guañabens 1 collaboration

M Kassim Javaid 1 collaboration

Terence W O'Neill 1 collaboration

R Graham G Russell 1 collaboration

Michael D Stone 1 collaboration

Keith Simpson 1 collaboration

Diana Wilkinson 1 collaboration

Ruth Wills 1 collaboration

M Carola Zillikens 1 collaboration

Stephen P Tuck 1 collaboration

Raquel Mesquita-Ribeiro 1 collaboration

Federico Dajas-Bailador 1 collaboration

Diyuan Li 1 collaboration

Jasmine Wyatt 1 collaboration

David M Rogers 1 collaboration

Lola M L Cusin 1 collaboration

Patrick J Tighe 1 collaboration

Jonathan D Hirst 1 collaboration

Manuel M Müller 1 collaboration