Roberto Bonasio

Affiliations

Epigenetics Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States.
Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States.

Publications (28)

A LAMP sequencing approach for high-throughput co-detection of SARS-CoV-2 and influenza virus in human saliva.

eLife

Avec: Robert Warneford-Thomson , Parisha P Shah , Patrick Lundgren , Jonathan Lerner , Jason Morgan , Antonio Davila , Benjamin S Abella , Kenneth Zaret , Jonathan Schug , Rajan Jain , Christoph A Thaiss , Roberto Bonasio

A ligation-independent sequencing method reveals tRNA-derived RNAs with blocked 3' termini.

Molecular cell

Avec: Alessandro Scacchetti , Emily J Shields , Natalie A Trigg , Grace S Lee , Jeremy E Wilusz , Colin C Conine , Roberto Bonasio

Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function.

Nature communications

Avec: Wenqing Ren , Nicole Medeiros , Robert Warneford-Thomson , Phillip Wulfridge , Qingqing Yan , Joyce Bian , Simone Sidoli , Benjamin A Garcia , Emmanuel Skordalakes , Eric Joyce , Roberto Bonasio , Kavitha Sarma

Deficiency of TET3 leads to a genome-wide DNA hypermethylation episignature in human whole blood.

NPJ genomic medicine

Avec: Michael A Levy , David B Beck , Kay Metcalfe , Sofia Douzgou , Sivagamy Sithambaram , Trudie Cottrell , Muhammad Ansar , Jennifer Kerkhof , Cyril Mignot , Marie-Christine Nougues , Boris Keren , Hannah W Moore , Renske Oegema , Jacques C Giltay , Marleen Simon , Richard H van Jaarsveld , Jessica Bos , Mieke van Haelst , M Mahdi Motazacker , Elles M J Boon , Gijs W E Santen , Claudia A L Ruivenkamp , Marielle Alders , Teresa Romeo Luperchio , Leandros Boukas , Keri Ramsey , Vinodh Narayanan , G Bradley Schaefer , Roberto Bonasio , Kimberly F Doheny , Roger E Stevenson , Siddharth Banka , Bekim Sadikovic , Jill A Fahrner

Long ant life span is maintained by a unique heat shock factor.

Genes & development

Avec: Karl M Glastad , Julian Roessler , Janko Gospocic , Roberto Bonasio , Shelley L Berger

Transcription factors interact with RNA to regulate genes.

Molecular cell

Avec: Ozgur Oksuz , Jonathan E Henninger , Robert Warneford-Thomson , Ming M Zheng , Hailey Erb , Adrienne Vancura , Kalon J Overholt , Susana Wilson Hawken , Salman F Banani , Richard Lauman , Lauren N Reich , Anne L Robertson , Nancy M Hannett , Tong I Lee , Leonard I Zon , Roberto Bonasio , Richard A Young

Ensheathing glia promote increased lifespan and healthy brain aging.

Aging cell

Avec: Lihong Sheng , Emily J Shields , Janko Gospocic , Masato Sorida , Linyang Ju , China N Byrns , Faith Carranza , Shelley L Berger , Nancy Bonini , Roberto Bonasio

RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2.

Nature structural & molecular biology

Avec: Qi Zhang , Nicholas J McKenzie , Robert Warneford-Thomson , Emma H Gail , Sarena F Flanigan , Brady M Owen , Richard Lauman , Vitalina Levina , Benjamin A Garcia , Ralf B Schittenhelm , Roberto Bonasio , Chen Davidovich

Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones.

Cell

Avec: Janko Gospocic , Karl M Glastad , Lihong Sheng , Emily J Shields , Shelley L Berger , Roberto Bonasio

TET2 chemically modifies tRNAs and regulates tRNA fragment levels.

Nature structural & molecular biology

Avec: Chongsheng He , Julianna Bozler , Kevin A Janssen , Jeremy E Wilusz , Benjamin A Garcia , Andrea J Schorn , Roberto Bonasio

DLBCL-associated NOTCH2 mutations escape ubiquitin-dependent degradation and promote chemoresistance.

Blood

Avec: Nan Zhou , Jaewoo Choi , Grant Grothusen , Bang-Jin Kim , Diqiu Ren , Zhendong Cao , Yiman Liu , Qinglan Li , Arati Inamdar , Thomas Beer , Hsin-Yao Tang , Eric Perkey , Ivan Maillard , Roberto Bonasio , Junwei Shi , Marco Ruella , Liling Wan , Luca Busino

IL-12 drives the differentiation of human T follicular regulatory cells.

Science immunology

Avec: Diana Castaño , Sidney Wang , Segovia Atencio-Garcia , Emily J Shields , Maria C Rico , Hannah Sharpe , Jacinta Bustamante , Allan Feng , Carole Le Coz , Neil Romberg , John W Tobias , Paul J Utz , Sarah E Henrickson , Jean-Laurent Casanova , Roberto Bonasio , Michela Locci

Social reprogramming in ants induces longevity-associated glia remodeling.

Science advances

Avec: Lihong Sheng , Emily J Shields , Janko Gospocic , Karl M Glastad , Puttachai Ratchasanmuang , Shelley L Berger , Arjun Raj , Shawn Little , Roberto Bonasio

Delineation of a Human Mendelian Disorder of the DNA Demethylation Machinery: TET3 Deficiency.

American journal of human genetics

Avec: David B Beck , Ana Petracovici , Chongsheng He , Hannah W Moore , Raymond J Louie , Muhammad Ansar , Sofia Douzgou , Sivagamy Sithambaram , Trudie Cottrell , Regie Lyn P Santos-Cortez , Eloise J Prijoles , Renee Bend , Boris Keren , Cyril Mignot , Marie-Christine Nougues , Katrin Õunap , Tiia Reimand , Sander Pajusalu , Muhammad Zahid , Muhammad Arif Nadeem Saqib , Julien Buratti , Eleanor G Seaby , Kirsty McWalter , Aida Telegrafi , Dustin Baldridge , Marwan Shinawi , Suzanne M Leal , G Bradley Schaefer , Roger E Stevenson , Siddharth Banka , Roberto Bonasio , Jill A Fahrner

Mapping Native R-Loops Genome-wide Using a Targeted Nuclease Approach.

Cell reports

Avec: Qingqing Yan , Emily J Shields , Roberto Bonasio , Kavitha Sarma

Distinct PRC2 subunits regulate maintenance and establishment of Polycomb repression during differentiation.

Molecular cell

Avec: Ana Petracovici , Roberto Bonasio

Genome annotation with long RNA reads reveals new patterns of gene expression and improves single-cell analyses in an ant brain.

BMC biology

Avec: Emily J Shields , Masato Sorida , Lihong Sheng , Bogdan Sieriebriennikov , Long Ding , Roberto Bonasio

Intrinsic maturation of sleep output neurons regulates sleep ontogeny in Drosophila.

Current biology : CB

Avec: Naihua N Gong , Hang Ngoc Bao Luong , An H Dang , Benjamin Mainwaring , Emily Shields , Karl Schmeckpeper , Roberto Bonasio , Matthew S Kayser

Expanding the Epitranscriptomic RNA Sequencing and Modification Mapping Mass Spectrometry Toolbox with Field Asymmetric Waveform Ion Mobility and Electrochemical Elution Liquid Chromatography.

Analytical chemistry

Avec: Richard Lauman , Hee Jong Kim , Lindsay K Pino , Alessandro Scacchetti , Yixuan Xie , Faith Robison , Simone Sidoli , Roberto Bonasio , Benjamin A Garcia

An efficient cloning method to expand vector and restriction site compatibility of Golden Gate Assembly.

Cell reports methods

Avec: Masato Sorida , Roberto Bonasio

Functionally distinct roles for TET-oxidized 5-methylcytosine bases in somatic reprogramming to pluripotency.

Molecular cell

Avec: Blake A Caldwell , Monica Yun Liu , Rexxi D Prasasya , Tong Wang , Jamie E DeNizio , N Adrian Leu , Nana Yaa A Amoh , Christopher Krapp , Yemin Lan , Emily J Shields , Roberto Bonasio , Christopher J Lengner , Rahul M Kohli , Marisa S Bartolomei

Active and Repressed Chromatin Domains Exhibit Distinct Nucleosome Segregation during DNA Replication.

Cell

Avec: Thelma M Escobar , Ozgur Oksuz , Ricardo Saldaña-Meyer , Nicolas Descostes , Roberto Bonasio , Danny Reinberg

lncRedibly versatile: biochemical and biological functions of long noncoding RNAs.

The Biochemical journal

Avec: Emily J Shields , Ana F Petracovici , Roberto Bonasio

H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification.

Science (New York, N.Y.)

Avec: Dario Nicetto , Greg Donahue , Tanya Jain , Tao Peng , Simone Sidoli , Lihong Sheng , Thomas Montavon , Justin S Becker , Jessica M Grindheim , Kimberly Blahnik , Benjamin A Garcia , Kai Tan , Roberto Bonasio , Thomas Jenuwein , Kenneth S Zaret

Correct dosage of X chromosome transcription is controlled by a nuclear pore component.

Cell reports

Avec: Jennifer R Aleman , Terra M Kuhn , Pau Pascual-Garcia , Janko Gospocic , Yemin Lan , Roberto Bonasio , Shawn C Little , Maya Capelson

Permethylation of Ribonucleosides Provides Enhanced Mass Spectrometry Quantification of Post-Transcriptional RNA Modifications.

Analytical chemistry

Avec: Yixuan Xie , Kevin A Janssen , Alessandro Scacchetti , Elizabeth G Porter , Zongtao Lin , Roberto Bonasio , Benjamin A Garcia

Hormonal gatekeeping via the blood-brain barrier governs caste-specific behavior in ants.

Cell

Avec: Linyang Ju , Karl M Glastad , Lihong Sheng , Janko Gospocic , Callum J Kingwell , Shawn M Davidson , Sarah D Kocher , Roberto Bonasio , Shelley L Berger

A ligation-independent sequencing method reveals tRNA-derived RNAs with blocked 3' termini.

bioRxiv : the preprint server for biology

Avec: Alessandro Scacchetti , Emily J Shields , Natalie A Trigg , Jeremy E Wilusz , Colin C Conine , Roberto Bonasio

Réseau de co-auteurs

Emily J Shields 10 collaborations

Benjamin A Garcia 6 collaborations

Janko Gospocic 6 collaborations

Lihong Sheng 6 collaborations

Shelley L Berger 5 collaborations

Robert Warneford-Thomson 4 collaborations

Alessandro Scacchetti 4 collaborations

Karl M Glastad 4 collaborations

Jeremy E Wilusz 3 collaborations

Simone Sidoli 3 collaborations

Richard Lauman 3 collaborations

Masato Sorida 3 collaborations

Natalie A Trigg 2 collaborations

Colin C Conine 2 collaborations

Qingqing Yan 2 collaborations

Kavitha Sarma 2 collaborations

David B Beck 2 collaborations

Sofia Douzgou 2 collaborations

Sivagamy Sithambaram 2 collaborations

Trudie Cottrell 2 collaborations

Muhammad Ansar 2 collaborations

Cyril Mignot 2 collaborations

Marie-Christine Nougues 2 collaborations

Boris Keren 2 collaborations

Hannah W Moore 2 collaborations

G Bradley Schaefer 2 collaborations

Roger E Stevenson 2 collaborations

Siddharth Banka 2 collaborations

Jill A Fahrner 2 collaborations

Ozgur Oksuz 2 collaborations

Linyang Ju 2 collaborations

Chongsheng He 2 collaborations

Kevin A Janssen 2 collaborations

Ana Petracovici 2 collaborations

Yixuan Xie 2 collaborations

Yemin Lan 2 collaborations

Parisha P Shah 1 collaboration

Patrick Lundgren 1 collaboration

Jonathan Lerner 1 collaboration

Jason Morgan 1 collaboration

Antonio Davila 1 collaboration

Benjamin S Abella 1 collaboration

Kenneth Zaret 1 collaboration

Jonathan Schug 1 collaboration

Rajan Jain 1 collaboration

Christoph A Thaiss 1 collaboration

Grace S Lee 1 collaboration

Wenqing Ren 1 collaboration

Nicole Medeiros 1 collaboration

Phillip Wulfridge 1 collaboration

Joyce Bian 1 collaboration

Emmanuel Skordalakes 1 collaboration

Eric Joyce 1 collaboration

Michael A Levy 1 collaboration

Kay Metcalfe 1 collaboration

Jennifer Kerkhof 1 collaboration

Renske Oegema 1 collaboration

Jacques C Giltay 1 collaboration

Marleen Simon 1 collaboration

Richard H van Jaarsveld 1 collaboration

Jessica Bos 1 collaboration

Mieke van Haelst 1 collaboration

M Mahdi Motazacker 1 collaboration

Elles M J Boon 1 collaboration

Gijs W E Santen 1 collaboration

Claudia A L Ruivenkamp 1 collaboration

Marielle Alders 1 collaboration

Teresa Romeo Luperchio 1 collaboration

Leandros Boukas 1 collaboration

Keri Ramsey 1 collaboration

Vinodh Narayanan 1 collaboration

Kimberly F Doheny 1 collaboration

Bekim Sadikovic 1 collaboration

Julian Roessler 1 collaboration

Jonathan E Henninger 1 collaboration

Ming M Zheng 1 collaboration

Hailey Erb 1 collaboration

Adrienne Vancura 1 collaboration

Kalon J Overholt 1 collaboration

Susana Wilson Hawken 1 collaboration

Salman F Banani 1 collaboration

Lauren N Reich 1 collaboration

Anne L Robertson 1 collaboration

Nancy M Hannett 1 collaboration

Tong I Lee 1 collaboration

Leonard I Zon 1 collaboration

Richard A Young 1 collaboration

China N Byrns 1 collaboration

Faith Carranza 1 collaboration

Nancy Bonini 1 collaboration

Qi Zhang 1 collaboration

Nicholas J McKenzie 1 collaboration

Emma H Gail 1 collaboration

Sarena F Flanigan 1 collaboration

Brady M Owen 1 collaboration

Vitalina Levina 1 collaboration

Ralf B Schittenhelm 1 collaboration

Chen Davidovich 1 collaboration

Julianna Bozler 1 collaboration

Andrea J Schorn 1 collaboration

Nan Zhou 1 collaboration

Jaewoo Choi 1 collaboration

Grant Grothusen 1 collaboration

Bang-Jin Kim 1 collaboration

Diqiu Ren 1 collaboration

Zhendong Cao 1 collaboration

Yiman Liu 1 collaboration

Qinglan Li 1 collaboration

Arati Inamdar 1 collaboration

Thomas Beer 1 collaboration

Hsin-Yao Tang 1 collaboration

Eric Perkey 1 collaboration

Ivan Maillard 1 collaboration

Junwei Shi 1 collaboration

Marco Ruella 1 collaboration

Liling Wan 1 collaboration

Luca Busino 1 collaboration

Diana Castaño 1 collaboration

Sidney Wang 1 collaboration

Segovia Atencio-Garcia 1 collaboration

Maria C Rico 1 collaboration

Hannah Sharpe 1 collaboration

Jacinta Bustamante 1 collaboration

Allan Feng 1 collaboration

Carole Le Coz 1 collaboration

Neil Romberg 1 collaboration

John W Tobias 1 collaboration

Paul J Utz 1 collaboration

Sarah E Henrickson 1 collaboration

Jean-Laurent Casanova 1 collaboration

Michela Locci 1 collaboration

Puttachai Ratchasanmuang 1 collaboration

Arjun Raj 1 collaboration

Shawn Little 1 collaboration

Raymond J Louie 1 collaboration

Regie Lyn P Santos-Cortez 1 collaboration

Eloise J Prijoles 1 collaboration

Renee Bend 1 collaboration

Katrin Õunap 1 collaboration

Tiia Reimand 1 collaboration

Sander Pajusalu 1 collaboration

Muhammad Zahid 1 collaboration

Muhammad Arif Nadeem Saqib 1 collaboration

Julien Buratti 1 collaboration

Eleanor G Seaby 1 collaboration

Kirsty McWalter 1 collaboration

Aida Telegrafi 1 collaboration

Dustin Baldridge 1 collaboration

Marwan Shinawi 1 collaboration

Suzanne M Leal 1 collaboration

Bogdan Sieriebriennikov 1 collaboration

Long Ding 1 collaboration

Naihua N Gong 1 collaboration

Hang Ngoc Bao Luong 1 collaboration

An H Dang 1 collaboration

Benjamin Mainwaring 1 collaboration

Emily Shields 1 collaboration

Karl Schmeckpeper 1 collaboration

Matthew S Kayser 1 collaboration

Hee Jong Kim 1 collaboration

Lindsay K Pino 1 collaboration

Faith Robison 1 collaboration

Blake A Caldwell 1 collaboration

Monica Yun Liu 1 collaboration

Rexxi D Prasasya 1 collaboration

Tong Wang 1 collaboration

Jamie E DeNizio 1 collaboration

N Adrian Leu 1 collaboration

Nana Yaa A Amoh 1 collaboration

Christopher Krapp 1 collaboration

Christopher J Lengner 1 collaboration

Rahul M Kohli 1 collaboration

Marisa S Bartolomei 1 collaboration

Thelma M Escobar 1 collaboration

Ricardo Saldaña-Meyer 1 collaboration

Nicolas Descostes 1 collaboration

Danny Reinberg 1 collaboration

Ana F Petracovici 1 collaboration

Dario Nicetto 1 collaboration

Greg Donahue 1 collaboration

Tanya Jain 1 collaboration

Tao Peng 1 collaboration

Thomas Montavon 1 collaboration

Justin S Becker 1 collaboration

Jessica M Grindheim 1 collaboration

Kimberly Blahnik 1 collaboration

Kai Tan 1 collaboration

Thomas Jenuwein 1 collaboration

Kenneth S Zaret 1 collaboration

Jennifer R Aleman 1 collaboration

Terra M Kuhn 1 collaboration

Pau Pascual-Garcia 1 collaboration

Shawn C Little 1 collaboration

Maya Capelson 1 collaboration

Elizabeth G Porter 1 collaboration

Zongtao Lin 1 collaboration

Callum J Kingwell 1 collaboration

Shawn M Davidson 1 collaboration

Sarah D Kocher 1 collaboration