S Alex Mitsialis

Affiliations

Division of Newborn Medicine, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Publications (18)

Photoreceptors inhibit pathological retinal angiogenesis through transcriptional regulation of Adam17 via c-Fos.

Angiogenesis

Avec: Xudong Wang , Tianxi Wang , Satoshi Kaneko , Emil Kriukov , Enton Lam , Manon Szczepan , Jasmine Chen , Austin Gregg , Xingyan Wang , Angeles Fernandez-Gonzalez , S Alex Mitsialis , Stella Kourembanas , Petr Baranov , Ye Sun

Mesenchymal stromal cell-derived small extracellular vesicles restore lung architecture and improve exercise capacity in a model of neonatal hyperoxia-induced lung injury.

Journal of extracellular vesicles

Avec: Gareth R Willis , Angeles Fernandez-Gonzalez , Monica Reis , Vincent Yeung , Xianlan Liu , Maria Ericsson , Nick A Andrews , S Alex Mitsialis , Stella Kourembanas

Intratracheal transplantation of trophoblast stem cells attenuates acute lung injury in mice.

Stem cell research & therapy

Avec: Junwen Han , Gu Li , Minmin Hou , Julie Ng , Min-Young Kwon , Kevin Xiong , Xiaoliang Liang , Elizabeth Taglauer , Yuanyuan Shi , S Alex Mitsialis , Stella Kourembanas , Souheil El-Chemaly , James A Lederer , Ivan O Rosas , Mark A Perrella , Xiaoli Liu

SOCS3 regulates pathological retinal angiogenesis through modulating SPP1 expression in microglia and macrophages.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Tianxi Wang , Satoshi Kaneko , Emil Kriukov , David Alvarez , Enton Lam , Yidi Wang , Sara La Manna , Daniela Marasco , Angeles Fernandez-Gonzalez , S Alex Mitsialis , Stella Kourembanas , Andreas Stahl , Mei Chen , Heping Xu , Petr Baranov , Guoshuai Cai , Ulrich H von Andrian , Ye Sun

Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes.

JCI insight

Avec: Nahal Mansouri , Gareth R Willis , Angeles Fernandez-Gonzalez , Monica Reis , Sina Nassiri , S Alex Mitsialis , Stella Kourembanas

Therapeutic Effects of Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles in Oxygen-Induced Multi-Organ Disease: A Developmental Perspective.

Frontiers in cell and developmental biology

Avec: Angeles Fernandez-Gonzalez , Gareth R Willis , Vincent Yeung , Monica Reis , Xianlan Liu , S Alex Mitsialis , Stella Kourembanas

Mesenchymal stromal cell-derived syndecan-2 regulates the immune response during sepsis to foster bacterial clearance and resolution of inflammation.

The FEBS journal

Avec: Junwen Han , Yuanyuan Shi , Gareth Willis , Jewel Imani , Min-Young Kwon , Gu Li , Ehab Ayaub , Sailaja Ghanta , Julie Ng , Narae Hwang , Konstantin Tsoyi , Souheil El-Chemaly , Stella Kourembanas , S Alex Mitsialis , Ivan O Rosas , Xiaoli Liu , Mark A Perrella

Immunoregulatory Macrophages Modify Local Pulmonary Immunity and Ameliorate Hypoxic Pulmonary Hypertension.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Angeles Fernandez-Gonzalez , Amit Mukhia , Janhavi Nadkarni , Gareth R Willis , Monica Reis , Kristjan Zhumka , Sally Vitali , Xianlan Liu , Alexandra Galls , S Alex Mitsialis , Stella Kourembanas

International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19.

Cytotherapy

Avec: Verena Börger , Daniel J Weiss , Johnathon D Anderson , Francesc E Borràs , Benedetta Bussolati , David R F Carter , Massimo Dominici , Juan M Falcón-Pérez , Mario Gimona , Andrew F Hill , Andrew M Hoffman , Dominique de Kleijn , Bruce L Levine , Rebecca Lim , Jan Lötvall , S Alex Mitsialis , Marta Monguió-Tortajada , Maurizio Muraca , Rienk Nieuwland , Anna Nowocin , Lorraine O'Driscoll , Luis A Ortiz , Donald G Phinney , Ilona Reischl , Eva Rohde , Ralf Sanzenbacher , Clotilde Théry , Wei Seong Toh , Kenneth W Witwer , Sai Kiang Lim , Bernd Giebel

Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications.

Journal of extracellular vesicles

Avec: Kenneth W Witwer , Bas W M Van Balkom , Stefania Bruno , Andre Choo , Massimo Dominici , Mario Gimona , Andrew F Hill , Dominique De Kleijn , Mickey Koh , Ruenn Chai Lai , S Alex Mitsialis , Luis A Ortiz , Eva Rohde , Takashi Asada , Wei Seong Toh , Daniel J Weiss , Lei Zheng , Bernd Giebel , Sai Kiang Lim

Heme oxygenase-1 dampens the macrophage sterile inflammasome response and regulates its components in the hypoxic lung.

American journal of physiology. Lung cellular and molecular physiology

Avec: Sally H Vitali , Angeles Fernandez-Gonzalez , Janhavi Nadkarni , April Kwong , Chase Rose , S Alex Mitsialis , Stella Kourembanas

Antenatal Mesenchymal Stromal Cell Extracellular Vesicle Therapy Prevents Preeclamptic Lung Injury in Mice.

American journal of respiratory cell and molecular biology

Avec: Elizabeth S Taglauer , Angeles Fernandez-Gonzalez , Gareth R Willis , Monica Reis , Vincent Yeung , Xianlan Liu , Lawrence S Prince , S Alex Mitsialis , Stella Kourembanas

Harnessing the therapeutic potential of the stem cell secretome in neonatal diseases.

Seminars in perinatology

Avec: Stephanie Tung , Eleni Delavogia , Angeles Fernandez-Gonzalez , S Alex Mitsialis , Stella Kourembanas

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Restore Thymic Architecture and T Cell Function Disrupted by Neonatal Hyperoxia.

Frontiers in immunology

Avec: Monica Reis , Gareth R Willis , Angeles Fernandez-Gonzalez , Vincent Yeung , Elizabeth Taglauer , Margaret Magaletta , Teagan Parsons , Alan Derr , Xianlan Liu , Rene Maehr , Stella Kourembanas , S Alex Mitsialis

Mesenchymal stromal cell-derived extracellular vesicle therapy prevents preeclamptic physiology through intrauterine immunomodulation†.

Biology of reproduction

Avec: Elizabeth S Taglauer , Angeles Fernandez-Gonzalez , Gareth R Willis , Monica Reis , Vincent Yeung , Xianlan Liu , S Alex Mitsialis , Stella Kourembanas

Antenatal mesenchymal stromal cell extracellular vesicle treatment preserves lung development in a model of bronchopulmonary dysplasia due to chorioamnionitis.

American journal of physiology. Lung cellular and molecular physiology

Avec: Alison N Abele , Elizabeth S Taglauer , Maricar Almeda , Noah Wilson , Abigail Abikoye , Gregory J Seedorf , S Alex Mitsialis , Stella Kourembanas , Steven H Abman

Immunoregulatory macrophages modify local pulmonary immunity and ameliorate hypoxic-pulmonary hypertension.

bioRxiv : the preprint server for biology

Mesenchymal stromal cell extracellular vesicles improve lung development in mechanically ventilated preterm lambs.

American journal of physiology. Lung cellular and molecular physiology

Avec: Kurt H Albertine , Andrew Rebentisch , Elaine Dawson , Jakob Van Boerum , Emily Major , Juraj Štipka , Hannah Foreman , David Headden , Zoë Vordos , Emily Beck , Zhengming Wang , Haixia Yang , Baifeng Yu , Mar Janna Dahl , Donald M Null , Davide Bizzotto , Chiara Veneroni , Anna Lavizzari , Raffaele L Dellacà , Eleni Delavogia , S Alex Mitsialis , Stella Kourembanas

Réseau de co-auteurs

Stella Kourembanas 16 collaborations

Angeles Fernandez-Gonzalez 12 collaborations

Gareth R Willis 8 collaborations

Monica Reis 8 collaborations

Xianlan Liu 7 collaborations

Vincent Yeung 5 collaborations

Janhavi Nadkarni 3 collaborations

Elizabeth S Taglauer 3 collaborations

Tianxi Wang 2 collaborations

Satoshi Kaneko 2 collaborations

Emil Kriukov 2 collaborations

Enton Lam 2 collaborations

Petr Baranov 2 collaborations

Ye Sun 2 collaborations

Junwen Han 2 collaborations

Gu Li 2 collaborations

Julie Ng 2 collaborations

Min-Young Kwon 2 collaborations

Elizabeth Taglauer 2 collaborations

Yuanyuan Shi 2 collaborations

Souheil El-Chemaly 2 collaborations

Ivan O Rosas 2 collaborations

Mark A Perrella 2 collaborations

Xiaoli Liu 2 collaborations

Amit Mukhia 2 collaborations

Kristjan Zhumka 2 collaborations

Sally Vitali 2 collaborations

Alexandra Galls 2 collaborations

Daniel J Weiss 2 collaborations

Massimo Dominici 2 collaborations

Mario Gimona 2 collaborations

Andrew F Hill 2 collaborations

Luis A Ortiz 2 collaborations

Eva Rohde 2 collaborations

Wei Seong Toh 2 collaborations

Kenneth W Witwer 2 collaborations

Sai Kiang Lim 2 collaborations

Bernd Giebel 2 collaborations

Eleni Delavogia 2 collaborations

Xudong Wang 1 collaboration

Manon Szczepan 1 collaboration

Jasmine Chen 1 collaboration

Austin Gregg 1 collaboration

Xingyan Wang 1 collaboration

Maria Ericsson 1 collaboration

Nick A Andrews 1 collaboration

Minmin Hou 1 collaboration

Kevin Xiong 1 collaboration

Xiaoliang Liang 1 collaboration

James A Lederer 1 collaboration

David Alvarez 1 collaboration

Yidi Wang 1 collaboration

Sara La Manna 1 collaboration

Daniela Marasco 1 collaboration

Andreas Stahl 1 collaboration

Mei Chen 1 collaboration

Heping Xu 1 collaboration

Guoshuai Cai 1 collaboration

Ulrich H von Andrian 1 collaboration

Nahal Mansouri 1 collaboration

Sina Nassiri 1 collaboration

Gareth Willis 1 collaboration

Jewel Imani 1 collaboration

Ehab Ayaub 1 collaboration

Sailaja Ghanta 1 collaboration

Narae Hwang 1 collaboration

Konstantin Tsoyi 1 collaboration

Verena Börger 1 collaboration

Johnathon D Anderson 1 collaboration

Francesc E Borràs 1 collaboration

Benedetta Bussolati 1 collaboration

David R F Carter 1 collaboration

Juan M Falcón-Pérez 1 collaboration

Andrew M Hoffman 1 collaboration

Dominique de Kleijn 1 collaboration

Bruce L Levine 1 collaboration

Rebecca Lim 1 collaboration

Jan Lötvall 1 collaboration

Marta Monguió-Tortajada 1 collaboration

Maurizio Muraca 1 collaboration

Rienk Nieuwland 1 collaboration

Anna Nowocin 1 collaboration

Lorraine O'Driscoll 1 collaboration

Donald G Phinney 1 collaboration

Ilona Reischl 1 collaboration

Ralf Sanzenbacher 1 collaboration

Clotilde Théry 1 collaboration

Bas W M Van Balkom 1 collaboration

Stefania Bruno 1 collaboration

Andre Choo 1 collaboration

Dominique De Kleijn 1 collaboration

Mickey Koh 1 collaboration

Ruenn Chai Lai 1 collaboration

Takashi Asada 1 collaboration

Lei Zheng 1 collaboration

Sally H Vitali 1 collaboration

April Kwong 1 collaboration

Chase Rose 1 collaboration

Lawrence S Prince 1 collaboration

Stephanie Tung 1 collaboration

Margaret Magaletta 1 collaboration

Teagan Parsons 1 collaboration

Alan Derr 1 collaboration

Rene Maehr 1 collaboration

Alison N Abele 1 collaboration

Maricar Almeda 1 collaboration

Noah Wilson 1 collaboration

Abigail Abikoye 1 collaboration

Gregory J Seedorf 1 collaboration

Steven H Abman 1 collaboration

Kurt H Albertine 1 collaboration

Andrew Rebentisch 1 collaboration

Elaine Dawson 1 collaboration

Jakob Van Boerum 1 collaboration

Emily Major 1 collaboration

Juraj Štipka 1 collaboration

Hannah Foreman 1 collaboration

David Headden 1 collaboration

Zoë Vordos 1 collaboration

Emily Beck 1 collaboration

Zhengming Wang 1 collaboration

Haixia Yang 1 collaboration

Baifeng Yu 1 collaboration

Mar Janna Dahl 1 collaboration

Donald M Null 1 collaboration

Davide Bizzotto 1 collaboration

Chiara Veneroni 1 collaboration

Anna Lavizzari 1 collaboration

Raffaele L Dellacà 1 collaboration