S Heitmeier

Affiliations

Bayer AG, Wuppertal, Germany.

Publications (30)

Dual Pathway Inhibition for Vascular Protection in Patients with Atherosclerotic Disease: Rationale and Review of the Evidence.

Thrombosis and haemostasis

Avec: Jeffrey Ian Weitz , Dominick J Angiolillo , Tobias Geisler , Stefan Heitmeier

A targeted proteomics investigation of the obesity paradox in venous thromboembolism.

Blood advances

Avec: Vincent Ten Cate , Thomas Koeck , Jürgen Prochaska , Andreas Schulz , Marina Panova-Noeva , Steffen Rapp , Lisa Eggebrecht , Michael Lenz , Julia Glunz , Madeleine Sauer , Raff Ewert , Michael Halank , Thomas Münzel , Stefan Heitmeier , Miguel A Andrade-Navarro , Karl J Lackner , Stavros V Konstantinides , Kirsten Leineweber , Philipp S Wild

Discovery of four plasmatic biomarkers potentially predicting cardiovascular outcome in peripheral artery disease.

Scientific reports

Avec: B M M Kremers , J N Posma , S Heitmeier , J Glunz , H Ten Cate , A Pallares Robles , J H C Daemen , A J Ten Cate-Hoek , B M E Mees , H M H Spronk

The effect of rivaroxaban on biomarkers in blood and plasma: a review of preclinical and clinical evidence.

Journal of thrombosis and thrombolysis

Avec: Sonja Schiffer , Stephan Schwers , Stefan Heitmeier

Design, Synthesis, and Pharmacological Characterization of a Neutral, Non-Prodrug Thrombin Inhibitor with Good Oral Pharmacokinetics.

Journal of medicinal chemistry

Avec: Alexander Hillisch , Kersten M Gericke , Swen Allerheiligen , Susanne Roehrig , Martina Schaefer , Adrian Tersteegen , Simone Schulz , Philip Lienau , Mark Gnoth , Vera Puetter , Roman C Hillig , Stefan Heitmeier

Variation of platelet function in clinical phenotypes of acute venous thromboembolism - Results from the GMP-VTE project.

Journal of thrombosis and haemostasis : JTH

Avec: Marina Panova-Noeva , Bianca Wagner , Markus Nagler , Thomas Koeck , Vincent Ten Cate , Lisa Eggebrecht , Jürgen H Prochaska , Imke Meyer , Christoph Gerdes , Henri M Spronk , Karl J Lackner , Hugo Ten Cate , Kirsten Leineweber , Stefan Heitmeier , Stavros Konstantinides , Philipp S Wild

Pharmacological profile of asundexian, a novel, orally bioavailable inhibitor of factor XIa.

Journal of thrombosis and haemostasis : JTH

Avec: Stefan Heitmeier , Mayken Visser , Adrian Tersteegen , Julia Dietze-Torres , Julia Glunz , Christoph Gerdes , Volker Laux , Jan Stampfuss , Susanne Roehrig

Effect of combining aspirin and rivaroxaban on atherosclerosis in mice.

Atherosclerosis

Avec: Steven P Grover , Taylor Coughlin , Salma M Fleifil , Jens J N Posma , Henri H M Spronk , Stefan Heitmeier , A Phillip Owens , Nigel Mackman

Association of FXI activity with thrombo-inflammation, extracellular matrix, lipid metabolism and apoptosis in venous thrombosis.

Scientific reports

Avec: Alejandro Pallares Robles , Vincent Ten Cate , Andreas Schulz , Jürgen H Prochaska , Steffen Rapp , Thomas Koeck , Marina Panova-Noeva , Stefan Heitmeier , Stephan Schwers , Kirsten Leineweber , Hans-Jürgen Seyfarth , Christian F Opitz , Henri Spronk , Christine Espinola-Klein , Karl J Lackner , Thomas Münzel , Miguel A Andrade-Navarro , Stavros V Konstantinides , Hugo Ten Cate , Philipp S Wild

The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses.

Translational psychiatry

Avec: Rosie M Walker , Michael Chong , Nicolas Perrot , Marie Pigeyre , Danni A Gadd , Aleks Stolicyn , Liu Shi , Archie Campbell , Xueyi Shen , Heather C Whalley , Alejo Nevado-Holgado , Andrew M McIntosh , Stefan Heitmeier , Sumathy Rangarajan , Martin O'Donnell , Eric E Smith , Salim Yusuf , William N Whiteley , Guillaume Paré

Subtype-specific plasma signatures of platelet-related protein releasate in acute pulmonary embolism.

Thrombosis research

Avec: Gaukhar Baidildinova , Vincent Ten Cate , Markus Nagler , Marina Panova-Noeva , Steffen Rapp , Thomas Köck , Jürgen H Prochaska , Stefan Heitmeier , Christoph Gerdes , Stephan Schwers , Stavros V Konstantinides , Thomas Münzel , Christine Espinola-Klein , Karl J Lackner , Henri M N Spronk , Hugo Ten Cate , Paola E J van der Meijden , Kirsten Leineweber , Philipp S Wild , Kerstin Jurk

Predictive value for increased activated factor XI activity in acute venous thromboembolism.

Journal of thrombosis and haemostasis : JTH

Avec: Magdolna Nagy , Alejandro Pallares Robles , Mayken Visser , Thomas Koeck , Vincent Ten Cate , Arina J Ten Cate-Hoek , Stephan Schwers , Stefan Heitmeier , Hugo Ten Cate , Philipp S Wild , Henri M H Spronk

Metabolism and Disposition of the Novel Oral Factor XIa Inhibitor Asundexian in Rats and in Humans.

European journal of drug metabolism and pharmacokinetics

Avec: Isabel Piel , Anna Engelen , Dieter Lang , Simone I Schulz , Michael Gerisch , Christine Brase , Wiebke Janssen , Lukas Fiebig , Stefan Heitmeier , Friederike Kanefendt

Differential roles of factors IX and XI in murine placenta and hemostasis under conditions of low tissue factor.

Blood advances

Avec: Steven P Grover , Clare M Schmedes , Alyson C Auriemma , Emily Butler , Molly L Parrish , Adam Miszta , Audrey C Cleuren , Mayken Visser , Stefan Heitmeier , Jens J Posma , Henri M Spronk , Silvio Antoniak , Alisa S Wolberg , Rafal Pawlinski , David Gailani , Nigel Mackman

Plasma Kallikrein Contributes to Coagulation in the Absence of Factor XI by Activating Factor IX.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Mayken Visser , René van Oerle , Hugo Ten Cate , Volker Laux , Nigel Mackman , Stefan Heitmeier , Henri M H Spronk

The dual FXa/thrombin inhibitor SATI prevents fibrin and platelet deposition in hypercoagulant rats.

Thrombosis research

Avec: Mercedes López , Stefan Heitmeier , Volker Laux , Goetz Nowak

A prospective cohort study to identify and evaluate endotypes of venous thromboembolism: Rationale and design of the Genotyping and Molecular Phenotyping in Venous ThromboEmbolism project (GMP-VTE).

Thrombosis research

Avec: V Ten Cate , T Koeck , M Panova-Noeva , S Rapp , J H Prochaska , M Lenz , A Schulz , L Eggebrecht , M I Hermanns , S Heitmeier , T Krahn , V Laux , T Münzel , K Leineweber , S V Konstantinides , P S Wild , Auteur inconnu

Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study.

Annals of intensive care

Avec: Felix Carl Fabian Schmitt , Vasil Manolov , Jakob Morgenstern , Thomas Fleming , Stefan Heitmeier , Florian Uhle , Mohammed Al-Saeedi , Thilo Hackert , Thomas Bruckner , Herbert Schöchl , Markus Alexander Weigand , Stefan Hofer , Thorsten Brenner

Vascular protective effect of aspirin and rivaroxaban upon endothelial denudation of the mouse carotid artery.

Scientific reports

Avec: T G Mastenbroek , M F A Karel , M Nagy , W Chayoua , E I J Korsten , D M Coenen , J Debets , J Konings , A E Brouns , P J A Leenders , H van Essen , R van Oerle , S Heitmeier , H M Spronk , M J E Kuijpers , J M E M Cosemans

Chymase Inhibition Resolves and Prevents Deep Vein Thrombosis Without Increasing Bleeding Time in the Mouse Model.

Journal of the American Heart Association

Avec: Catherine Lapointe , Laurence Vincent , Hugo Giguère , Mannix Auger-Messier , Adel Schwertani , Denan Jin , Shinji Takai , Gunnar Pejler , Martin G Sirois , Hanna Tinel , Stefan Heitmeier , Pedro D'Orléans-Juste

Design and Preclinical Characterization Program toward Asundexian (BAY 2433334), an Oral Factor XIa Inhibitor for the Prevention and Treatment of Thromboembolic Disorders.

Journal of medicinal chemistry

Avec: Susanne Roehrig , Jens Ackerstaff , Eloísa Jiménez Núñez , Henrik Teller , Pascal Ellerbrock , Katharina Meier , Stefan Heitmeier , Adrian Tersteegen , Jan Stampfuss , Dieter Lang , Karl-Heinz Schlemmer , Martina Schaefer , Kersten M Gericke , Tom Kinzel , Daniel Meibom , Martina Schmidt , Christoph Gerdes , Markus Follmann , Alexander Hillisch

Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice.

Scientific reports

Avec: Jelle J Posthuma , Jens J N Posma , Rene van Oerle , Peter Leenders , Rick H van Gorp , Armand M G Jaminon , Nigel Mackman , Stefan Heitmeier , Leon J Schurgers , Hugo Ten Cate , Henri M H Spronk

Role of Factor XIa and Plasma Kallikrein in Arterial and Venous Thrombosis.

Thrombosis and haemostasis

Avec: Mayken Visser , Stefan Heitmeier , Hugo Ten Cate , Henri M H Spronk

Comprehensive platelet phenotyping supports the role of platelets in the pathogenesis of acute venous thromboembolism - results from clinical observation studies.

EBioMedicine

Avec: Marina Panova-Noeva , Bianca Wagner , Markus Nagler , Thomas Koeck , Vincent Ten Cate , Jürgen H Prochaska , Stefan Heitmeier , Imke Meyer , Christoph Gerdes , Volker Laux , Stavros Konstantinides , Henri M Spronk , Thomas Münzel , Karl J Lackner , Kirsten Leineweber , Hugo Ten Cate , Philipp S Wild

Protein expression profiling suggests relevance of noncanonical pathways in isolated pulmonary embolism.

Blood

Avec: Vincent Ten Cate , Jürgen H Prochaska , Andreas Schulz , Thomas Koeck , Alejandro Pallares Robles , Michael Lenz , Lisa Eggebrecht , Steffen Rapp , Marina Panova-Noeva , H Ardeschir Ghofrani , F Joachim Meyer , Christine Espinola-Klein , Karl J Lackner , Matthias Michal , Alexander K Schuster , Konstantin Strauch , Alexander M Zink , Volker Laux , Stefan Heitmeier , Stavros V Konstantinides , Thomas Münzel , Miguel A Andrade-Navarro , Kirsten Leineweber , Philipp S Wild

Reversing Rivaroxaban Anticoagulation as Part of a Multimodal Hemostatic Intervention in a Polytrauma Animal Model.

Anesthesiology

Avec: Farahnaz Rayatdoost , Till Braunschweig , Benjamin Maron , Herbert Schöchl , Necib Akman , Rolf Rossaint , Eva Herzog , Stefan Heitmeier , Oliver Grottke

Integrating Mechanisms in Thrombotic Peripheral Arterial Disease.

Pharmaceuticals (Basel, Switzerland)

Avec: Magdolna Nagy , Paola E J van der Meijden , Julia Glunz , Leon Schurgers , Esther Lutgens , Hugo Ten Cate , Stefan Heitmeier , Henri M H Spronk

Unsupervised clustering of venous thromboembolism patients by clinical features at presentation identifies novel endotypes that improve prognostic stratification.

Thrombosis research

Avec: Alejandro Pallares Robles , Vincent Ten Cate , Michael Lenz , Andreas Schulz , Jürgen H Prochaska , Steffen Rapp , Thomas Koeck , Kirsten Leineweber , Stefan Heitmeier , Christian F Opitz , Matthias Held , Christine Espinola-Klein , Karl J Lackner , Thomas Münzel , Stavros V Konstantinides , Arina Ten Cate-Hoek , Hugo Ten Cate , Philipp S Wild

Rivaroxaban attenuates neutrophil maturation in the bone marrow niche.

Basic research in cardiology

Avec: R Schneckmann , M Döring , S Gerfer , S Gorressen , S Heitmeier , C Helten , A Polzin , C Jung , M Kelm , A C Fender , U Flögel , M Grandoch

Plasma protein signatures for high on-treatment platelet reactivity to aspirin and clopidogrel in peripheral artery disease.

Thrombosis research

Avec: G Baidildinova , A Pallares Robles , V Ten Cate , B M M Kremers , S Heitmeier , H Ten Cate , B M E Mees , H M H Spronk , P S Wild , A J Ten Cate-Hoek , K Jurk

Réseau de co-auteurs

Stefan Heitmeier 25 collaborations

Hugo Ten Cate 10 collaborations

Vincent Ten Cate 8 collaborations

Philipp S Wild 8 collaborations

Thomas Koeck 7 collaborations

Karl J Lackner 7 collaborations

Kirsten Leineweber 7 collaborations

Marina Panova-Noeva 6 collaborations

Thomas Münzel 6 collaborations

Jürgen H Prochaska 6 collaborations

Steffen Rapp 5 collaborations

Stavros V Konstantinides 5 collaborations

Christoph Gerdes 5 collaborations

Mayken Visser 5 collaborations

Volker Laux 5 collaborations

Henri M H Spronk 5 collaborations

Andreas Schulz 4 collaborations

Stephan Schwers 4 collaborations

Nigel Mackman 4 collaborations

Alejandro Pallares Robles 4 collaborations

Christine Espinola-Klein 4 collaborations

Lisa Eggebrecht 3 collaborations

Michael Lenz 3 collaborations

Julia Glunz 3 collaborations

Miguel A Andrade-Navarro 3 collaborations

Susanne Roehrig 3 collaborations

Adrian Tersteegen 3 collaborations

Markus Nagler 3 collaborations

Henri M Spronk 3 collaborations

B M M Kremers 2 collaborations

H Ten Cate 2 collaborations

A Pallares Robles 2 collaborations

A J Ten Cate-Hoek 2 collaborations

B M E Mees 2 collaborations

H M H Spronk 2 collaborations

Alexander Hillisch 2 collaborations

Kersten M Gericke 2 collaborations

Martina Schaefer 2 collaborations

Bianca Wagner 2 collaborations

Imke Meyer 2 collaborations

Stavros Konstantinides 2 collaborations

Jan Stampfuss 2 collaborations

Steven P Grover 2 collaborations

Jens J N Posma 2 collaborations

Christian F Opitz 2 collaborations

Paola E J van der Meijden 2 collaborations

Magdolna Nagy 2 collaborations

Dieter Lang 2 collaborations

V Ten Cate 2 collaborations

P S Wild 2 collaborations

Herbert Schöchl 2 collaborations

Jeffrey Ian Weitz 1 collaboration

Dominick J Angiolillo 1 collaboration

Tobias Geisler 1 collaboration

Jürgen Prochaska 1 collaboration

Madeleine Sauer 1 collaboration

Raff Ewert 1 collaboration

Michael Halank 1 collaboration

J N Posma 1 collaboration

J Glunz 1 collaboration

J H C Daemen 1 collaboration

Sonja Schiffer 1 collaboration

Swen Allerheiligen 1 collaboration

Simone Schulz 1 collaboration

Philip Lienau 1 collaboration

Mark Gnoth 1 collaboration

Vera Puetter 1 collaboration

Roman C Hillig 1 collaboration

Julia Dietze-Torres 1 collaboration

Taylor Coughlin 1 collaboration

Salma M Fleifil 1 collaboration

Henri H M Spronk 1 collaboration

A Phillip Owens 1 collaboration

Hans-Jürgen Seyfarth 1 collaboration

Henri Spronk 1 collaboration

Rosie M Walker 1 collaboration

Michael Chong 1 collaboration

Nicolas Perrot 1 collaboration

Marie Pigeyre 1 collaboration

Danni A Gadd 1 collaboration

Aleks Stolicyn 1 collaboration

Liu Shi 1 collaboration

Archie Campbell 1 collaboration

Xueyi Shen 1 collaboration

Heather C Whalley 1 collaboration

Alejo Nevado-Holgado 1 collaboration

Andrew M McIntosh 1 collaboration

Sumathy Rangarajan 1 collaboration

Martin O'Donnell 1 collaboration

Eric E Smith 1 collaboration

Salim Yusuf 1 collaboration

William N Whiteley 1 collaboration

Guillaume Paré 1 collaboration

Gaukhar Baidildinova 1 collaboration

Thomas Köck 1 collaboration

Henri M N Spronk 1 collaboration

Kerstin Jurk 1 collaboration

Arina J Ten Cate-Hoek 1 collaboration

Isabel Piel 1 collaboration

Anna Engelen 1 collaboration

Simone I Schulz 1 collaboration

Michael Gerisch 1 collaboration

Christine Brase 1 collaboration

Wiebke Janssen 1 collaboration

Lukas Fiebig 1 collaboration

Friederike Kanefendt 1 collaboration

Clare M Schmedes 1 collaboration

Alyson C Auriemma 1 collaboration

Emily Butler 1 collaboration

Molly L Parrish 1 collaboration

Adam Miszta 1 collaboration

Audrey C Cleuren 1 collaboration

Jens J Posma 1 collaboration

Silvio Antoniak 1 collaboration

Alisa S Wolberg 1 collaboration

Rafal Pawlinski 1 collaboration

David Gailani 1 collaboration

René van Oerle 1 collaboration

Mercedes López 1 collaboration

Goetz Nowak 1 collaboration

T Koeck 1 collaboration

M Panova-Noeva 1 collaboration

S Rapp 1 collaboration

J H Prochaska 1 collaboration

M Lenz 1 collaboration

A Schulz 1 collaboration

L Eggebrecht 1 collaboration

M I Hermanns 1 collaboration

T Krahn 1 collaboration

V Laux 1 collaboration

T Münzel 1 collaboration

K Leineweber 1 collaboration

S V Konstantinides 1 collaboration

None None 1 collaboration

Felix Carl Fabian Schmitt 1 collaboration

Vasil Manolov 1 collaboration

Jakob Morgenstern 1 collaboration

Thomas Fleming 1 collaboration

Florian Uhle 1 collaboration

Mohammed Al-Saeedi 1 collaboration

Thilo Hackert 1 collaboration

Thomas Bruckner 1 collaboration

Markus Alexander Weigand 1 collaboration

Stefan Hofer 1 collaboration

Thorsten Brenner 1 collaboration

T G Mastenbroek 1 collaboration

M F A Karel 1 collaboration

M Nagy 1 collaboration

W Chayoua 1 collaboration

E I J Korsten 1 collaboration

D M Coenen 1 collaboration

J Debets 1 collaboration

J Konings 1 collaboration

A E Brouns 1 collaboration

P J A Leenders 1 collaboration

H van Essen 1 collaboration

R van Oerle 1 collaboration

H M Spronk 1 collaboration

M J E Kuijpers 1 collaboration

J M E M Cosemans 1 collaboration

Catherine Lapointe 1 collaboration

Laurence Vincent 1 collaboration

Hugo Giguère 1 collaboration

Mannix Auger-Messier 1 collaboration

Adel Schwertani 1 collaboration

Denan Jin 1 collaboration

Shinji Takai 1 collaboration

Gunnar Pejler 1 collaboration

Martin G Sirois 1 collaboration

Hanna Tinel 1 collaboration

Pedro D'Orléans-Juste 1 collaboration

Jens Ackerstaff 1 collaboration

Eloísa Jiménez Núñez 1 collaboration

Henrik Teller 1 collaboration

Pascal Ellerbrock 1 collaboration

Katharina Meier 1 collaboration

Karl-Heinz Schlemmer 1 collaboration

Tom Kinzel 1 collaboration

Daniel Meibom 1 collaboration

Martina Schmidt 1 collaboration

Markus Follmann 1 collaboration

Jelle J Posthuma 1 collaboration

Rene van Oerle 1 collaboration

Peter Leenders 1 collaboration

Rick H van Gorp 1 collaboration

Armand M G Jaminon 1 collaboration

Leon J Schurgers 1 collaboration

H Ardeschir Ghofrani 1 collaboration

F Joachim Meyer 1 collaboration

Matthias Michal 1 collaboration

Alexander K Schuster 1 collaboration

Konstantin Strauch 1 collaboration

Alexander M Zink 1 collaboration

Farahnaz Rayatdoost 1 collaboration

Till Braunschweig 1 collaboration

Benjamin Maron 1 collaboration

Necib Akman 1 collaboration

Rolf Rossaint 1 collaboration

Eva Herzog 1 collaboration

Oliver Grottke 1 collaboration

Leon Schurgers 1 collaboration

Esther Lutgens 1 collaboration

Matthias Held 1 collaboration

Arina Ten Cate-Hoek 1 collaboration

R Schneckmann 1 collaboration

M Döring 1 collaboration

S Gerfer 1 collaboration

S Gorressen 1 collaboration

C Helten 1 collaboration

A Polzin 1 collaboration

C Jung 1 collaboration

M Kelm 1 collaboration

A C Fender 1 collaboration

U Flögel 1 collaboration

M Grandoch 1 collaboration

G Baidildinova 1 collaboration

K Jurk 1 collaboration