Sergio A Gradilone

Affiliations

The Hormel Institute, University of Minnesota, Austin, MN, United States.
Masonic Cancer Center, University of Minnesota, Minneapolis, MN, United States.

Publications (17)

Role of Glucose Metabolism Reprogramming in the Pathogenesis of Cholangiocarcinoma.

Frontiers in medicine

Avec: Kishor Pant , Seth Richard , Estanislao Peixoto , Sergio A Gradilone

HDAC6-dependent ciliophagy is involved in ciliary loss and cholangiocarcinoma growth in human cells and murine models.

American journal of physiology. Gastrointestinal and liver physiology

Avec: Estanislao Peixoto , Sujeong Jin , Kristen Thelen , Aalekhya Biswas , Seth Richard , Manuela Morleo , Adrian Mansini , Stephanie Holtorf , Fabrizia Carbone , Nunzia Pastore , Andrea Ballabio , Brunella Franco , Sergio A Gradilone

The Chemosensory Function of Primary Cilia Regulates Cholangiocyte Migration, Invasion, and Tumor Growth.

Hepatology (Baltimore, Md.)

Avec: Adrian P Mansini , Estanislao Peixoto , Sujeong Jin , Seth Richard , Sergio A Gradilone

The NAMPT Inhibitor FK866 in Combination with Cisplatin Reduces Cholangiocarcinoma Cells Growth.

Cells

Avec: Kishor Pant , Seth Richard , Estanislao Peixoto , Jun Yin , Davis M Seelig , Pietro Carotenuto , Massimiliano Salati , Brunella Franco , Lewis R Roberts , Sergio A Gradilone

Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease.

Hepatology (Baltimore, Md.)

Avec: Francisco J Caballero-Camino , Ivan Rivilla , Elisa Herraez , Oscar Briz , Alvaro Santos-Laso , Laura Izquierdo-Sanchez , Pui Y Lee-Law , Pedro M Rodrigues , Patricia Munoz-Garrido , Sujeong Jin , Estanislao Peixoto , Seth Richard , Sergio A Gradilone , Maria J Perugorria , Manel Esteller , Luis Bujanda , Jose J G Marin , Jesus M Banales , Fernando P Cossío

Characterization of Novel Murine and Human PDAC Cell Models: Identifying the Role of Intestine Specific Homeobox Gene ISX in Hypoxia and Disease Progression.

Translational oncology

Avec: Arsheed A Ganaie , Aijaz Parray , Tabish Hussain , Ashraf Shabaneh , Anmbreen Jamroze , Marina G Ferrari , Lei Wang , D Joshua Liao , Shahriar Koochekpour , Sanjeev Nanda , Jinhua Wang , Yibin Deng , Sergio A Gradilone , Edward H Hinchcliffe , Badrinath R Konety , Mohammad Saleem

Inhibition of triple‑negative breast cancer proliferation and motility by reactivating p53 and inhibiting overactivated Akt.

Oncology reports

Avec: Wei Cao , Renhui Shen , Seth Richard , Yu Liu , Mohammad Jalalirad , Margot P Cleary , Antonio B D'Assoro , Sergio A Gradilone , Da-Qing Yang

NAMPT Overexpression Drives Cell Growth in Polycystic Liver Disease Through Mitochondrial Metabolism Regulation.

The American journal of pathology

Avec: Kishor Pant , Sergio A Gradilone

Cholangiocyte ciliary defects induce sustained epidermal growth factor receptor signaling.

Hepatology (Baltimore, Md.)

Avec: Kishor Pant , Seth Richard , Estanislao Peixoto , Subheksha Baral , Rendong Yang , Yanan Ren , Tatyana V Masyuk , Nicholas F LaRusso , Sergio A Gradilone

Role of Histone Deacetylases in Carcinogenesis: Potential Role in Cholangiocarcinoma.

Cells

Avec: Kishor Pant , Estanislao Peixoto , Seth Richard , Sergio A Gradilone

Cholangiocarcinoma 2020: the next horizon in mechanisms and management.

Nature reviews. Gastroenterology & hepatology

Avec: Jesus M Banales , Jose J G Marin , Angela Lamarca , Pedro M Rodrigues , Shahid A Khan , Lewis R Roberts , Vincenzo Cardinale , Guido Carpino , Jesper B Andersen , Chiara Braconi , Diego F Calvisi , Maria J Perugorria , Luca Fabris , Luke Boulter , Rocio I R Macias , Eugenio Gaudio , Domenico Alvaro , Sergio A Gradilone , Mario Strazzabosco , Marco Marzioni , Cédric Coulouarn , Laura Fouassier , Chiara Raggi , Pietro Invernizzi , Joachim C Mertens , Anja Moncsek , Sumera Rizvi , Julie Heimbach , Bas Groot Koerkamp , Jordi Bruix , Alejandro Forner , John Bridgewater , Juan W Valle , Gregory J Gores

Short-Chain Fatty Acid Butyrate Induces Cilia Formation and Potentiates the Effects of HDAC6 Inhibitors in Cholangiocarcinoma Cells.

Frontiers in cell and developmental biology

Avec: Kishor Pant , Seth Richard , Sergio A Gradilone

The primary cilium: Its role as a tumor suppressor organelle.

Biochemical pharmacology

Avec: Estanislao Peixoto , Seth Richard , Kishor Pant , Aalekhya Biswas , Sergio A Gradilone

Histone Deacetylase Sirtuin 1 Promotes Loss of Primary Cilia in Cholangiocarcinoma.

Hepatology (Baltimore, Md.)

Avec: Kishor Pant , Estanislao Peixoto , Seth Richard , Aalekhya Biswas , M Gerard O'Sullivan , Nasra Giama , Yeonjung Ha , Jun Yin , Pietro Carotenuto , Massimiliano Salati , Yanan Ren , Rendong Yang , Brunella Franco , Lewis R Roberts , Sergio A Gradilone

The Role of Gut Microbiome-Derived Short-Chain Fatty Acid Butyrate in Hepatobiliary Diseases.

The American journal of pathology

Avec: Kishor Pant , Senthil K Venugopal , Maria J Lorenzo Pisarello , Sergio A Gradilone

Cilia and Cancer: From Molecular Genetics to Therapeutic Strategies.

Genes

Avec: Pietro Carotenuto , Sergio A Gradilone , Brunella Franco

Myeloid differentiation factor-2/LY96, a potential predictive biomarker of metastasis and poor outcomes in prostate cancer: clinical implications as a potential therapeutic target.

Oncogene

Avec: Marina G Ferrari , Alexis P Jimenez-Uribe , Li Wang , Luke H Hoeppner , Paari Murugan , Eunsil Hahm , Jindan Yu , Timothy M Kuzel , Sergio A Gradilone , Adrian P Mansini

Réseau de co-auteurs

Seth Richard 11 collaborations

Kishor Pant 9 collaborations

Estanislao Peixoto 9 collaborations

Brunella Franco 4 collaborations

Sujeong Jin 3 collaborations

Aalekhya Biswas 3 collaborations

Pietro Carotenuto 3 collaborations

Lewis R Roberts 3 collaborations

Adrian P Mansini 2 collaborations

Jun Yin 2 collaborations

Massimiliano Salati 2 collaborations

Pedro M Rodrigues 2 collaborations

Maria J Perugorria 2 collaborations

Jose J G Marin 2 collaborations

Jesus M Banales 2 collaborations

Marina G Ferrari 2 collaborations

Rendong Yang 2 collaborations

Yanan Ren 2 collaborations

Kristen Thelen 1 collaboration

Manuela Morleo 1 collaboration

Adrian Mansini 1 collaboration

Stephanie Holtorf 1 collaboration

Fabrizia Carbone 1 collaboration

Nunzia Pastore 1 collaboration

Andrea Ballabio 1 collaboration

Davis M Seelig 1 collaboration

Francisco J Caballero-Camino 1 collaboration

Ivan Rivilla 1 collaboration

Elisa Herraez 1 collaboration

Oscar Briz 1 collaboration

Alvaro Santos-Laso 1 collaboration

Laura Izquierdo-Sanchez 1 collaboration

Pui Y Lee-Law 1 collaboration

Patricia Munoz-Garrido 1 collaboration

Manel Esteller 1 collaboration

Luis Bujanda 1 collaboration

Fernando P Cossío 1 collaboration

Arsheed A Ganaie 1 collaboration

Aijaz Parray 1 collaboration

Tabish Hussain 1 collaboration

Ashraf Shabaneh 1 collaboration

Anmbreen Jamroze 1 collaboration

Lei Wang 1 collaboration

D Joshua Liao 1 collaboration

Shahriar Koochekpour 1 collaboration

Sanjeev Nanda 1 collaboration

Jinhua Wang 1 collaboration

Yibin Deng 1 collaboration

Edward H Hinchcliffe 1 collaboration

Badrinath R Konety 1 collaboration

Mohammad Saleem 1 collaboration

Wei Cao 1 collaboration

Renhui Shen 1 collaboration

Yu Liu 1 collaboration

Mohammad Jalalirad 1 collaboration

Margot P Cleary 1 collaboration

Antonio B D'Assoro 1 collaboration

Da-Qing Yang 1 collaboration

Subheksha Baral 1 collaboration

Tatyana V Masyuk 1 collaboration

Nicholas F LaRusso 1 collaboration

Angela Lamarca 1 collaboration

Shahid A Khan 1 collaboration

Vincenzo Cardinale 1 collaboration

Guido Carpino 1 collaboration

Jesper B Andersen 1 collaboration

Chiara Braconi 1 collaboration

Diego F Calvisi 1 collaboration

Luca Fabris 1 collaboration

Luke Boulter 1 collaboration

Rocio I R Macias 1 collaboration

Eugenio Gaudio 1 collaboration

Domenico Alvaro 1 collaboration

Mario Strazzabosco 1 collaboration

Marco Marzioni 1 collaboration

Cédric Coulouarn 1 collaboration

Laura Fouassier 1 collaboration

Chiara Raggi 1 collaboration

Pietro Invernizzi 1 collaboration

Joachim C Mertens 1 collaboration

Anja Moncsek 1 collaboration

Sumera Rizvi 1 collaboration

Julie Heimbach 1 collaboration

Bas Groot Koerkamp 1 collaboration

Jordi Bruix 1 collaboration

Alejandro Forner 1 collaboration

John Bridgewater 1 collaboration

Juan W Valle 1 collaboration

Gregory J Gores 1 collaboration

M Gerard O'Sullivan 1 collaboration

Nasra Giama 1 collaboration

Yeonjung Ha 1 collaboration

Senthil K Venugopal 1 collaboration

Maria J Lorenzo Pisarello 1 collaboration

Alexis P Jimenez-Uribe 1 collaboration

Li Wang 1 collaboration

Luke H Hoeppner 1 collaboration

Paari Murugan 1 collaboration

Eunsil Hahm 1 collaboration

Jindan Yu 1 collaboration

Timothy M Kuzel 1 collaboration