Subash Sad

Affiliations

Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Centre for Infection, Immunity, and Inflammation (CI3), University of Ottawa, Ottawa, Ontario, Canada. Electronic address: Subash.sad@uottawa.ca.

Publications (16)

Isolates of Salmonella typhimurium circumvent NLRP3 inflammasome recognition in macrophages during the chronic phase of infection.

The Journal of biological chemistry

Avec: David Cai , Willie June Brickey , Jenny P Ting , Subash Sad

Foxo3a tempers excessive glutaminolysis in activated T cells to prevent fatal gut inflammation in the murine IL-10

Cell death and differentiation

Avec: Stephanie Hajjar , Nayanan Nathan , Julie Joseph , Walid Mottawea , Ardeshir Ariana , Sergey Pyatibrat , Mary-Ellen Harper , Tommy Alain , Alexandre Blais , Ryan C Russell , Subash Sad

Roles of natural resistance-associated macrophage protein-1 in modulating bacterial distribution and immune responses during Salmonella enterica serovar Typhimurium infection in murine pregnancy.

American journal of reproductive immunology (New York, N.Y. : 1989)

Avec: Gerard Agbayani , Kristina Clark , Subash Sad , Shawn P Murphy , Lakshmi Krishnan

The TNFα/TNFR2 axis mediates natural killer cell proliferation by promoting aerobic glycolysis.

Cellular & molecular immunology

Avec: Abrar Ul Haq Khan , Alaa Kassim Ali , Bryan Marr , Donghyeon Jo , Simin Ahmadvand , Claire Fong-McMaster , Saeedah Musaed Almutairi , Lisheng Wang , Subash Sad , Mary-Ellen Harper , Seung-Hwan Lee

Science translational medicine

Avec: Bojan Shutinoski , Mansoureh Hakimi , Irene E Harmsen , Michaela Lunn , Juliana Rocha , Nathalie Lengacher , Yi Yuan Zhou , Jasmine Khan , Angela Nguyen , Quinton Hake-Volling , Daniel El-Kodsi , Juan Li , Azadeh Alikashani , Claudine Beauchamp , Jay Majithia , Kevin Coombs , Derya Shimshek , Paul C Marcogliese , David S Park , John D Rioux , Dana J Philpott , John M Woulfe , Shawn Hayley , Subash Sad , Julianna J Tomlinson , Earl G Brown , Michael G Schlossmacher

Coating M-CSF on plastic surface results in the generation of increased numbers of macrophages in vitro.

Journal of immunological methods

Avec: Sanathan Sadh , Stephanie Hajjar , Ardeshir Ariana , Melissa Sen Phuong , David Cai , Parva Thakker , Subash Sad

The transcription factor Cdx2 regulates inflammasome activity through expression of the NLRP3 suppressor TRIM31 to maintain intestinal homeostasis.

The Journal of biological chemistry

Avec: Sanzida Jahan , Nidaa Awaja , Bradley Hess , Stephanie Hajjar , Subash Sad , David Lohnes

Ripk3 licenced protection against microbial infection in the absence of Caspase1-11 inflammasome.

Microbes and infection

Avec: Bojan Shutinoski , Rajen Patel , Julianna J Tomlinson , Michael G Schlossmacher , Subash Sad

AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles.

Cell reports

Avec: Truc T Losier , Mercy Akuma , Olivia C McKee-Muir , Nicholas D LeBlond , Yujin Suk , Reham M Alsaadi , Zhihao Guo , Ryan Reshke , Subash Sad , François-Xavier Campbell-Valois , Derrick J Gibbings , Morgan D Fullerton , Ryan C Russell

RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified

Frontiers in immunology

Avec: Aamir Rana , Felipe Campos de Almeida , Henry A Paico Montero , Maryanne M Gonzales Carazas , Karina R Bortoluci , Subash Sad , Gustavo P Amarante-Mendes

Tristetraprolin regulates necroptosis during tonic Toll-like receptor 4 (TLR4) signaling in murine macrophages.

The Journal of biological chemistry

Avec: Ardeshir Ariana , Norah A Alturki , Stephanie Hajjar , Deborah J Stumpo , Christopher Tiedje , Emad S Alnemri , Matthias Gaestel , Perry J Blackshear , Subash Sad

Type I interferons differentially modulate maternal host immunity to infection by Listeria monocytogenes and Salmonella enterica serovar Typhimurium during pregnancy.

American journal of reproductive immunology (New York, N.Y. : 1989)

Avec: Gerard Agbayani , Kristina Wachholz , Shawn P Murphy , Subash Sad , Lakshmi Krishnan

Impairment in inflammasome signaling by the chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients results in an increase in inflammatory response.

Cell death & disease

Avec: Melissa S Phuong , Rafael E Hernandez , Daniel J Wolter , Lucas R Hoffman , Subash Sad

IFN-alpha receptor deficiency enhances host resistance to oral Salmonella enterica serovar Typhimurium infection during murine pregnancy.

American journal of reproductive immunology (New York, N.Y. : 1989)

Avec: Gerard Agbayani , Kristina Clark , Jagdeep K Sandhu , Melissa Hewitt , Subash Sad , Shawn P Murphy , Lakshmi Krishnan

XIAP promotes the expansion and limits the contraction of CD8 T cell response through cell extrinsic and intrinsic mechanisms respectively.

PLoS pathogens

Avec: Parva Thakker , Ardeshir Ariana , Stephanie Hajjar , David Cai , Dikchha Rijal , Subash Sad

Regulation of Zfp36 by ISGF3 and MK2 restricts the expression of inflammatory cytokines during necroptosis stimulation.

Cell death & disease

Avec: Sahil Yadav , Rayan El Hamra , Norah A Alturki , Ardeshir Ariana , Avni Bhan , Kate Hurley , Matthias Gaestel , Perry J Blackshear , Alexandre Blais , Subash Sad

Réseau de co-auteurs

Stephanie Hajjar 5 collaborations

Ardeshir Ariana 5 collaborations

David Cai 3 collaborations

Gerard Agbayani 3 collaborations

Shawn P Murphy 3 collaborations

Lakshmi Krishnan 3 collaborations

Mary-Ellen Harper 2 collaborations

Alexandre Blais 2 collaborations

Ryan C Russell 2 collaborations

Kristina Clark 2 collaborations

Bojan Shutinoski 2 collaborations

Julianna J Tomlinson 2 collaborations

Michael G Schlossmacher 2 collaborations

Parva Thakker 2 collaborations

Norah A Alturki 2 collaborations

Matthias Gaestel 2 collaborations

Perry J Blackshear 2 collaborations

Willie June Brickey 1 collaboration

Jenny P Ting 1 collaboration

Nayanan Nathan 1 collaboration

Julie Joseph 1 collaboration

Walid Mottawea 1 collaboration

Sergey Pyatibrat 1 collaboration

Tommy Alain 1 collaboration

Abrar Ul Haq Khan 1 collaboration

Alaa Kassim Ali 1 collaboration

Bryan Marr 1 collaboration

Donghyeon Jo 1 collaboration

Simin Ahmadvand 1 collaboration

Claire Fong-McMaster 1 collaboration

Saeedah Musaed Almutairi 1 collaboration

Lisheng Wang 1 collaboration

Seung-Hwan Lee 1 collaboration

Mansoureh Hakimi 1 collaboration

Irene E Harmsen 1 collaboration

Michaela Lunn 1 collaboration

Juliana Rocha 1 collaboration

Nathalie Lengacher 1 collaboration

Yi Yuan Zhou 1 collaboration

Jasmine Khan 1 collaboration

Angela Nguyen 1 collaboration

Quinton Hake-Volling 1 collaboration

Daniel El-Kodsi 1 collaboration

Juan Li 1 collaboration

Azadeh Alikashani 1 collaboration

Claudine Beauchamp 1 collaboration

Jay Majithia 1 collaboration

Kevin Coombs 1 collaboration

Derya Shimshek 1 collaboration

Paul C Marcogliese 1 collaboration

David S Park 1 collaboration

John D Rioux 1 collaboration

Dana J Philpott 1 collaboration

John M Woulfe 1 collaboration

Shawn Hayley 1 collaboration

Earl G Brown 1 collaboration

Sanathan Sadh 1 collaboration

Melissa Sen Phuong 1 collaboration

Sanzida Jahan 1 collaboration

Nidaa Awaja 1 collaboration

Bradley Hess 1 collaboration

David Lohnes 1 collaboration

Rajen Patel 1 collaboration

Truc T Losier 1 collaboration

Mercy Akuma 1 collaboration

Olivia C McKee-Muir 1 collaboration

Nicholas D LeBlond 1 collaboration

Yujin Suk 1 collaboration

Reham M Alsaadi 1 collaboration

Zhihao Guo 1 collaboration

Ryan Reshke 1 collaboration

François-Xavier Campbell-Valois 1 collaboration

Derrick J Gibbings 1 collaboration

Morgan D Fullerton 1 collaboration

Aamir Rana 1 collaboration

Felipe Campos de Almeida 1 collaboration

Henry A Paico Montero 1 collaboration

Maryanne M Gonzales Carazas 1 collaboration

Karina R Bortoluci 1 collaboration

Gustavo P Amarante-Mendes 1 collaboration

Deborah J Stumpo 1 collaboration

Christopher Tiedje 1 collaboration

Emad S Alnemri 1 collaboration

Kristina Wachholz 1 collaboration

Melissa S Phuong 1 collaboration

Rafael E Hernandez 1 collaboration

Daniel J Wolter 1 collaboration

Lucas R Hoffman 1 collaboration

Jagdeep K Sandhu 1 collaboration

Melissa Hewitt 1 collaboration

Dikchha Rijal 1 collaboration

Sahil Yadav 1 collaboration

Rayan El Hamra 1 collaboration

Avni Bhan 1 collaboration

Kate Hurley 1 collaboration