Toshiyasu Iwao

Affiliations

Department of Internal Medicine, Aidu Chuo Hospital, Aizuwakamatsu, Japan.

Publications (25)

In vitro bile acid-dependent hepatocyte toxicity assay system using human induced pluripotent stem cell-derived hepatocytes: Current status and disadvantages to overcome.

Drug metabolism and pharmacokinetics

Avec: Yoko Sakai , Takahiro Iwao , Takeshi Susukida , Takumi Nukaga , Akinori Takemura , Shuichi Sekine , Kousei Ito , Tamihide Matsunaga

Development of an in vitro cholestatic drug-induced liver injury evaluation system using HepG2-hNTCP-C4 cells in sandwich configuration.

Toxicology in vitro : an international journal published in association with BIBRA

Avec: Yoko Sakai , Hiroki Okumura , Takahiro Iwao , Koichi Watashi , Kousei Ito , Tamihide Matsunaga

Isolation of induced pluripotent stem cell-derived endothelial progenitor cells from sac-like structures.

Biochemical and biophysical research communications

Avec: Hiromasa Aoki , Misaki Yamashita , Tadahiro Hashita , Mizuki Nakayama , Mayuko Yagi , Takahiro Iwao , Tamihide Matsunaga

Efficient differentiation and purification of human induced pluripotent stem cell-derived endothelial progenitor cells and expansion with the use of inhibitors of ROCK, TGF-β, and GSK3β.

Heliyon

Avec: Hiromasa Aoki , Misaki Yamashita , Tadahiro Hashita , Koichi Ogami , Shinichi Hoshino , Takahiro Iwao , Tamihide Matsunaga

Prevalence of type 2 diabetes by age, sex and geographical area among two million public assistance recipients in Japan: a cross-sectional study using a nationally representative claims database.

Journal of epidemiology and community health

Avec: Tami Sengoku , Tatsuro Ishizaki , Yoshihito Goto , Tomohide Iwao , Shosuke Ohtera , Michi Sakai , Genta Kato , Takeo Nakayama , Yoshimitsu Takahashi

Simultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase-Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell-Derived Small Intestinal Epithelial Cells.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Takashi Kitaguchi , Taisei Mizota , Mina Ito , Katsutoshi Ohno , Kazuhiro Kobayashi , Isamu Ogawa , Shimeng Qiu , Takahiro Iwao , Nobumitsu Hanioka , Mitsuru Tanaka , Tamihide Matsunaga

Clinical Features and Survival of Young Adults with Stage IV Gastric Cancer: a Japanese Population-Based Study.

Journal of gastrointestinal cancer

Avec: Ryuya Yamamoto , Michitaka Honda , Hidetaka Kawamura , Hiroshi Kobayashi , Koichi Takiguchi , Atsushi Muto , Shigeru Yamazaki , Yasushi Teranishi , Satoru Shiraso , Koji Kono , Soshi Hori , Takahiro Kamiga , Toshiyasu Iwao , Naoyuki Yamashita

Ivermectin Inhibits HBV Entry into the Nucleus by Suppressing KPNA2.

Viruses

Avec: Anna Nakanishi , Hiroki Okumura , Tadahiro Hashita , Aya Yamashita , Yuka Nishimura , Chihiro Watanabe , Sakina Kamimura , Sanae Hayashi , Shuko Murakami , Kyoko Ito , Takahiro Iwao , Akari Ikeda , Tomoyasu Hirose , Toshiaki Sunazuka , Yasuhito Tanaka , Tamihide Matsunaga

Senescence in brain pericytes attenuates blood-brain barrier function in vitro: A comparison of serially passaged and isolated pericytes from aged rat brains.

Biochemical and biophysical research communications

Avec: Takuro Iwao , Fuyuko Takata , Junichi Matsumoto , Yuki Goto , Hisataka Aridome , Miho Yasunaga , Miki Yokoya , Yasufumi Kataoka , Shinya Dohgu

Comparison of mRNA expression profiles of drug-metabolizing enzymes and transporters in fresh and cryopreserved cynomolgus monkey hepatocytes.

Drug metabolism and pharmacokinetics

Avec: Akiko Koeda , Takahiro Iwao , Anna Nakanishi , Shota Mizuno , Misaki Yamashita , Yoko Sakai , Katsunori Nakamura , Tamihide Matsunaga

Calibration of the retardation inhomogeneity for the compensator-rotating imaging ellipsometer.

Applied optics

Avec: Lianhua Jin , Yuki Iizuka , Takashi Iwao , Eiichi Kondoh , Makoto Uehara , Bernard Gelloz

Establishment of a novel culture method for maintaining intestinal stem cells derived from human induced pluripotent stem cells.

Biology open

Avec: Satoshi Kondo , Shota Mizuno , Tadahiro Hashita , Takahiro Iwao , Tamihide Matsunaga

Serum amyloid A-induced blood-brain barrier dysfunction associated with decreased claudin-5 expression in rat brain endothelial cells and its inhibition by high-density lipoprotein in vitro.

Neuroscience letters

Avec: Junichi Matsumoto , Shinya Dohgu , Fuyuko Takata , Takuro Iwao , Ikuya Kimura , Misaki Tomohiro , Kentaro Aono , Yasufumi Kataoka , Atsushi Yamauchi

Radial spatiotemporal evolution of rf magnetic field and plasma current in a very-high-frequency plasma source over a wide range of plasma density and pressure.

Physical review. E

Avec: Jianping Zhao , Peter L G Ventzek , Barton Lane , Toshihiko Iwao , Kiyotaka Ishibashi

A Survey on Cases of Serious and High-Risk Child Abuse with Trauma Using the Database of Health Insurance Claims.

Studies in health technology and informatics

Avec: Tomohide Iwao , Michi Sakai

Impact of histological subtype on prognosis in stage IV colorectal cancer: A population-based cohort study.

PloS one

Avec: Teppei Miyakawa , Hidetaka Kawamura , Michitaka Honda , Yoshinao Takano , Shunji Kinuta , Takahiro Kamiga , Shigeru Yamazaki , Atsushi Muto , Satoru Shiraso , Naoyuki Yamashita , Toshiyasu Iwao , Koji Kono , Shinichi Konno

Simultaneous and sequential combination of genetic and epigenetic biomarkers for the presence of high-grade dysplasia in patients with pancreatic cyst: Discovery in cyst fluid and test in pancreatic juice.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]

Avec: Tatsuo Hata , Masamichi Mizuma , Takashi Kusakabe , Hodaka Amano , Toru Furukawa , Toshiyasu Iwao , Michiaki Unno

Generation of Brain Microvascular Endothelial-like Cells from Human iPS Cell-Derived Endothelial Progenitor Cells Using TGF-β Receptor Inhibitor, Laminin 511 Fragment, and Neuronal Cell Culture Supplements.

Pharmaceutics

Avec: Hiromasa Aoki , Misaki Yamashita , Tadahiro Hashita , Takahiro Iwao , Mineyoshi Aoyama , Tamihide Matsunaga

Effect of Anagliptin on Vascular Injury in the Femoral Artery of Type 2 Diabetic Rats.

Biological & pharmaceutical bulletin

Avec: Masato Noda , Chigusa Kikuchi , Eisei Hori , Takahiro Iwao , Chie Nagami , Masayoshi Takeuchi , Tamihide Matsunaga

Prognostic impact and survival outcomes of colon perforation in patients with metastatic colorectal cancer: a multicenter retrospective cohort study.

International journal of clinical oncology

Avec: Eiichi Nakao , Hidetaka Kawamura , Michitaka Honda , Yoshinao Takano , Shunji Kinuta , Takahiro Kamiga , Shigeru Yamazaki , Atsushi Muto , Satoru Shiraso , Naoyuki Yamashita , Toshiyasu Iwao , Koji Kono , Shinichi Konno

New Maintenance Culture Method for Intestinal Stem Cells Derived from Human Induced Pluripotent Stem Cells.

Biological & pharmaceutical bulletin

Avec: Shota Mizuno , Yumi Jinnoh , Ayaka Arita , Shimeng Qiu , Tadahiro Hashita , Eisei Hori , Takahiro Iwao , Tamihide Matsunaga

Pharmacokinetic functions of human induced pluripotent stem cell-derived small intestinal epithelial cells.

Drug metabolism and pharmacokinetics

Avec: Tomoki Kabeya , Shinji Mima , Yuki Imakura , Toshihide Miyashita , Izumi Ogura , Tadanori Yamada , Tomoya Yasujima , Hiroaki Yuasa , Takahiro Iwao , Tamihide Matsunaga

Pancreaticoduodenectomy following total occlusion of the superior mesenteric artery: a case report and literature review.

Surgical case reports

Avec: Reo Ohtsuka , Hodaka Amano , Michiyo Hashimoto , Toshiyasu Iwao

Validation of claims data to identify death among aged persons utilizing enrollment data from health insurance unions.

Environmental health and preventive medicine

Avec: M Sakai , S Ohtera , T Iwao , Y Neff , G Kato , Y Takahashi , T Nakayama , Auteur inconnu

Clinical features of isolated proximal-type immunoglobulin G4-related sclerosing cholangitis.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society

Avec: Yuri Takagi , Kensuke Kubota , Takuya Takayanagi , Yusuke Kurita , Ken Ishii , Sho Hasegawa , Akito Iwasaki , Takamitsu Sato , Yuji Fujita , Shingo Kato , Koichi Kagawa , Seitaro Watanabe , Yusuke Sekino , Kunihiro Hosono , Nobuyuki Matsuhashi , Shoji Yamanaka , Toshiyasu Iwao , Koji Yoshida , Atsushi Nakajima

Réseau de co-auteurs

Takahiro Iwao 12 collaborations

Tamihide Matsunaga 12 collaborations

Tadahiro Hashita 6 collaborations

Misaki Yamashita 4 collaborations

Yoko Sakai 3 collaborations

Hiromasa Aoki 3 collaborations

Michitaka Honda 3 collaborations

Hidetaka Kawamura 3 collaborations

Atsushi Muto 3 collaborations

Shigeru Yamazaki 3 collaborations

Satoru Shiraso 3 collaborations

Koji Kono 3 collaborations

Takahiro Kamiga 3 collaborations

Naoyuki Yamashita 3 collaborations

Shota Mizuno 3 collaborations

Kousei Ito 2 collaborations

Hiroki Okumura 2 collaborations

Tomohide Iwao 2 collaborations

Michi Sakai 2 collaborations

Shimeng Qiu 2 collaborations

Anna Nakanishi 2 collaborations

Takuro Iwao 2 collaborations

Fuyuko Takata 2 collaborations

Junichi Matsumoto 2 collaborations

Yasufumi Kataoka 2 collaborations

Shinya Dohgu 2 collaborations

Yoshinao Takano 2 collaborations

Shunji Kinuta 2 collaborations

Shinichi Konno 2 collaborations

Hodaka Amano 2 collaborations

Eisei Hori 2 collaborations

Takeshi Susukida 1 collaboration

Takumi Nukaga 1 collaboration

Akinori Takemura 1 collaboration

Shuichi Sekine 1 collaboration

Koichi Watashi 1 collaboration

Mizuki Nakayama 1 collaboration

Mayuko Yagi 1 collaboration

Koichi Ogami 1 collaboration

Shinichi Hoshino 1 collaboration

Tami Sengoku 1 collaboration

Tatsuro Ishizaki 1 collaboration

Yoshihito Goto 1 collaboration

Shosuke Ohtera 1 collaboration

Genta Kato 1 collaboration

Takeo Nakayama 1 collaboration

Yoshimitsu Takahashi 1 collaboration

Takashi Kitaguchi 1 collaboration

Taisei Mizota 1 collaboration

Mina Ito 1 collaboration

Katsutoshi Ohno 1 collaboration

Kazuhiro Kobayashi 1 collaboration

Isamu Ogawa 1 collaboration

Nobumitsu Hanioka 1 collaboration

Mitsuru Tanaka 1 collaboration

Ryuya Yamamoto 1 collaboration

Hiroshi Kobayashi 1 collaboration

Koichi Takiguchi 1 collaboration

Yasushi Teranishi 1 collaboration

Soshi Hori 1 collaboration

Aya Yamashita 1 collaboration

Yuka Nishimura 1 collaboration

Chihiro Watanabe 1 collaboration

Sakina Kamimura 1 collaboration

Sanae Hayashi 1 collaboration

Shuko Murakami 1 collaboration

Kyoko Ito 1 collaboration

Akari Ikeda 1 collaboration

Tomoyasu Hirose 1 collaboration

Toshiaki Sunazuka 1 collaboration

Yasuhito Tanaka 1 collaboration

Yuki Goto 1 collaboration

Hisataka Aridome 1 collaboration

Miho Yasunaga 1 collaboration

Miki Yokoya 1 collaboration

Akiko Koeda 1 collaboration

Katsunori Nakamura 1 collaboration

Lianhua Jin 1 collaboration

Yuki Iizuka 1 collaboration

Takashi Iwao 1 collaboration

Eiichi Kondoh 1 collaboration

Makoto Uehara 1 collaboration

Bernard Gelloz 1 collaboration

Satoshi Kondo 1 collaboration

Ikuya Kimura 1 collaboration

Misaki Tomohiro 1 collaboration

Kentaro Aono 1 collaboration

Atsushi Yamauchi 1 collaboration

Jianping Zhao 1 collaboration

Peter L G Ventzek 1 collaboration

Barton Lane 1 collaboration

Toshihiko Iwao 1 collaboration

Kiyotaka Ishibashi 1 collaboration

Teppei Miyakawa 1 collaboration

Tatsuo Hata 1 collaboration

Masamichi Mizuma 1 collaboration

Takashi Kusakabe 1 collaboration

Toru Furukawa 1 collaboration

Michiaki Unno 1 collaboration

Mineyoshi Aoyama 1 collaboration

Masato Noda 1 collaboration

Chigusa Kikuchi 1 collaboration

Chie Nagami 1 collaboration

Masayoshi Takeuchi 1 collaboration

Eiichi Nakao 1 collaboration

Yumi Jinnoh 1 collaboration

Ayaka Arita 1 collaboration

Tomoki Kabeya 1 collaboration

Shinji Mima 1 collaboration

Yuki Imakura 1 collaboration

Toshihide Miyashita 1 collaboration

Izumi Ogura 1 collaboration

Tadanori Yamada 1 collaboration

Tomoya Yasujima 1 collaboration

Hiroaki Yuasa 1 collaboration

Reo Ohtsuka 1 collaboration

Michiyo Hashimoto 1 collaboration

M Sakai 1 collaboration

S Ohtera 1 collaboration

T Iwao 1 collaboration

Y Neff 1 collaboration

G Kato 1 collaboration

Y Takahashi 1 collaboration

T Nakayama 1 collaboration

None None 1 collaboration

Yuri Takagi 1 collaboration

Kensuke Kubota 1 collaboration

Takuya Takayanagi 1 collaboration

Yusuke Kurita 1 collaboration

Ken Ishii 1 collaboration

Sho Hasegawa 1 collaboration

Akito Iwasaki 1 collaboration

Takamitsu Sato 1 collaboration

Yuji Fujita 1 collaboration

Shingo Kato 1 collaboration

Koichi Kagawa 1 collaboration

Seitaro Watanabe 1 collaboration

Yusuke Sekino 1 collaboration

Kunihiro Hosono 1 collaboration

Nobuyuki Matsuhashi 1 collaboration

Shoji Yamanaka 1 collaboration

Koji Yoshida 1 collaboration

Atsushi Nakajima 1 collaboration