Trond Ulven

Affiliations

Department of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen, Denmark.

Publications (29)

Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production.

Cell reports

Avec: Valentin Sencio , Adeline Barthelemy , Luciana P Tavares , Marina G Machado , Daphnée Soulard , Céline Cuinat , Celso Martins Queiroz-Junior , Marie-Louise Noordine , Sophie Salomé-Desnoulez , Lucie Deryuter , Benoit Foligné , Céline Wahl , Benoit Frisch , Angelica T Vieira , Christophe Paget , Graeme Milligan , Trond Ulven , Isabelle Wolowczuk , Christelle Faveeuw , Ronan Le Goffic , Muriel Thomas , Stéphanie Ferreira , Mauro M Teixeira , François Trottein

Effects of Delayed-Release Olive Oil and Hydrolyzed Pine Nut Oil on Glucose Tolerance, Incretin Secretion and Appetite in Humans.

Nutrients

Avec: Karina V Sørensen , Mads H Kaspersen , Jeppe H Ekberg , Annette Bauer-Brandl , Trond Ulven , Kurt Højlund

Pathophysiological regulation of lung function by the free fatty acid receptor FFA4.

Science translational medicine

Avec: Rudi Prihandoko , Davinder Kaur , Coen H Wiegman , Elisa Alvarez-Curto , Chantal Donovan , Latifa Chachi , Trond Ulven , Martha R Tyas , Eloise Euston , Zhaoyang Dong , Abdulrahman Ghali M Alharbi , Richard Y Kim , Jack G Lowe , Philip M Hansbro , Kian Fan Chung , Christopher E Brightling , Graeme Milligan , Andrew B Tobin

An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights.

Journal of medicinal chemistry

Avec: Meryem Köse , Thanigaimalai Pillaiyar , Vigneshwaran Namasivayam , Elisabetta De Filippo , Katharina Sylvester , Trond Ulven , Ivar von Kügelgen , Christa E Müller

The Two Formyl Peptide Receptors Differently Regulate GPR84-Mediated Neutrophil NADPH Oxidase Activity.

Journal of innate immunity

Avec: Jonas Mårtensson , Martina Sundqvist , Asmita Manandhar , Loukas Ieremias , Linjie Zhang , Trond Ulven , Xin Xie , Lena Björkman , Huamei Forsman

Synthesis and cellular evaluation of click-chemistry probes to study the biological effects of alpha, beta-unsaturated carbonyls.

Redox biology

Avec: Chiara Morozzi , Max Sauerland , Luke F Gamon , Asmita Manandhar , Trond Ulven , Michael J Davies

Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets.

Diabetologia

Avec: Estela Lorza-Gil , Gabriele Kaiser , Christopher Carlein , Markus D A Hoffmann , Gabriele M König , Sieglinde Haug , Leticia Prates Roma , Elisabeth Rexen Ulven , Trond Ulven , Evi Kostenis , Andreas L Birkenfeld , Hans-Ulrich Häring , Susanne Ullrich , Felicia Gerst

Structure-activity relationship of GPR15L peptide analogues and investigation of their interaction with the GPR15 receptor.

Basic & clinical pharmacology & toxicology

Avec: Yufang Deng , Claudia V Perez Almeria , Lieke van Gijzel , Kay Schaller , Line Vedel , David E Gloriam , Trond Ulven , Hans Bräuner-Osborne

Chronic administration of hydrolysed pine nut oil to mice improves insulin sensitivity and glucose tolerance and increases energy expenditure via a free fatty acid receptor 4-dependent mechanism.

The British journal of nutrition

Avec: Edward T Wargent , Małgorzata A Kępczyńska , Mads H Kaspersen , Elisabeth Rexen Ulven , Jonathan R S Arch , Trond Ulven , Claire J Stocker

Acute effects of delayed-release hydrolyzed pine nut oil on glucose tolerance, incretins, ghrelin and appetite in healthy humans.

Clinical nutrition (Edinburgh, Scotland)

Avec: Karina V Sørensen , Svend S Korfitzen , Mads H Kaspersen , Elisabeth Rexen Ulven , Jeppe H Ekberg , Annette Bauer-Brandl , Trond Ulven , Kurt Højlund

Novel GPR120 agonist TUG891 modulates fat taste perception and preference and activates tongue-brain-gut axis in mice.

Journal of lipid research

Avec: Babar Murtaza , Aziz Hichami , Amira S Khan , Bharat Shimpukade , Trond Ulven , Mehmet Hakan Ozdener , Naim A Khan

Chemogenetics defines a short-chain fatty acid receptor gut-brain axis.

eLife

Avec: Natasja Barki , Daniele Bolognini , Ulf Börjesson , Laura Jenkins , John Riddell , David I Hughes , Trond Ulven , Brian D Hudson , Elisabeth Rexen Ulven , Niek Dekker , Andrew B Tobin , Graeme Milligan

Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization.

Science signaling

Avec: Viktoria M S Kjær , Viktorija Daugvilaite , Tomasz M Stepniewski , Christian M Madsen , Astrid S Jørgensen , Kaustubh R Bhuskute , Asuka Inoue , Trond Ulven , Tau Benned-Jensen , Siv A Hjorth , Gertrud M Hjortø , Ee Von Moo , Jana Selent , Mette M Rosenkilde

Structure-Activity Relationship Studies and Optimization of 4-Hydroxypyridones as GPR84 Agonists.

Journal of medicinal chemistry

Avec: Loukas Ieremias , Mads H Kaspersen , Asmita Manandhar , Katrine Schultz-Knudsen , Christina Ioanna Vrettou , Rina Pokhrel , Christoffer V Heidtmann , Laura Jenkins , Christina Kanellou , Sara Marsango , Yueming Li , Hans Bräuner-Osborne , Elisabeth Rexen Ulven , Graeme Milligan , Trond Ulven

Activation of GPR40 induces hypothalamic neurogenesis through p38- and BDNF-dependent mechanisms.

Scientific reports

Avec: Daiane F Engel , Vanessa C D Bobbo , Carina S Solon , Guilherme A Nogueira , Alexandre Moura-Assis , Natalia F Mendes , Ariane M Zanesco , Athanasios Papangelis , Trond Ulven , Licio A Velloso

Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators.

Journal of medicinal chemistry

Avec: Elisabeth Rexen Ulven , Tezz Quon , Eugenia Sergeev , Natasja Barki , Matjaz Brvar , Brian D Hudson , Palash Dutta , Anders Højgaard Hansen , Line Ø Bielefeldt , Andrew B Tobin , Christine J McKenzie , Graeme Milligan , Trond Ulven

Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT.

Molecular metabolism

Avec: Anna Sofie Husted , Jeppe H Ekberg , Emma Tripp , Tinne A D Nissen , Stijn Meijnikman , Shannon L O'Brien , Trond Ulven , Yair Acherman , Sjoerd C Bruin , Max Nieuwdorp , Zach Gerhart-Hines , Davide Calebiro , Lars O Dragsted , Thue W Schwartz

Identification of 5-HT2 Serotonin Receptor Modulators through the Synthesis of a Diverse, Tropane- and Quinuclidine-alkaloid-Inspired Compound Library.

Journal of medicinal chemistry

Avec: Ruwei Yao , Anders A Jensen , Hogan P Bryce-Rogers , Katrine Schultz-Knudsen , Libin Zhou , Nicklas P Hovendal , Henrik Pedersen , Mariusz Kubus , Trond Ulven , Luca Laraia

Functional-Group-Tolerant Pd-Catalyzed Carbonylative Negishi Coupling with Aryl Iodides.

The Journal of organic chemistry

Avec: Dmitrii V Kalinin , Trond Ulven

Selective Allosteric Modulation of N-Terminally Cleaved, but Not Full Length CCL3 in CCR1.

ACS pharmacology & translational science

Avec: Olav Larsen , Michael Lückmann , Wijnand J C van der Velden , Marta Oliva-Santiago , Matjaz Brvar , Trond Ulven , Thomas M Frimurer , Stefanie Karlshøj , Mette M Rosenkilde

Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival.

The Journal of allergy and clinical immunology

Avec: Anna Theiler , Thomas Bärnthaler , Wolfgang Platzer , Georg Richtig , Miriam Peinhaupt , Sonja Rittchen , Julia Kargl , Trond Ulven , Leigh M Marsh , Gunther Marsche , Rufina Schuligoi , Eva M Sturm , Akos Heinemann

Structure-Activity Relationship Explorations and Discovery of a Potent Antagonist for the Free Fatty Acid Receptor 2.

ChemMedChem

Avec: Anders Højgaard Hansen , Henriette B Christensen , Sunil K Pandey , Eugenia Sergeev , Alice Valentini , Julia Dunlop , Domonkos Dedeo , Simone Fratta , Brian D Hudson , Graeme Milligan , Trond Ulven , Elisabeth Rexen Ulven

FFA2-, but not FFA3-agonists inhibit GSIS of human pseudoislets: a comparative study with mouse islets and rat INS-1E cells.

Scientific reports

Avec: Estela Lorza-Gil , Gabriele Kaiser , Elisabeth Rexen Ulven , Gabriele M König , Felicia Gerst , Morgana Barroso Oquendo , Andreas L Birkenfeld , Hans-Ulrich Häring , Evi Kostenis , Trond Ulven , Susanne Ullrich

Discovery of GPR183 Agonists Based on an Antagonist Scaffold.

ChemMedChem

Avec: Viktoria M S Kjaer , Loukas Ieremias , Viktorija Daugvilaite , Michael Lückmann , Thomas M Frimurer , Trond Ulven , Mette M Rosenkilde , Jon Våbenø

Synthesis of Lysophosphatidylcholine and Mixed Phosphatidylcholine.

The Journal of organic chemistry

Avec: Athanasios Papangelis , Trond Ulven

Hypothalamic free fatty acid receptor-1 regulates whole-body energy balance.

Molecular metabolism

Avec: Nathalia R V Dragano , Edward Milbank , Roberta Haddad-Tóvolli , Pablo Garrido-Gil , Eva Nóvoa , Marcos F Fondevilla , Valentina Capelli , Ariane Maria Zanesco , Carina Solon , Joseane Morari , Leticia Pires , Ánxela Estevez-Salguero , Daniel Beiroa , Ismael González-García , Olga Barca-Mayo , Carlos Diéguez , Ruben Nogueiras , José L Labandeira-García , Elisabeth Rexen Ulven , Trond Ulven , Marc Claret , Licio A Velloso , Miguel Lopez

Identification of galectin-1 and other cellular targets of alpha,beta-unsaturated carbonyl compounds, including dimethylfumarate, by use of click-chemistry probes.

Redox biology

Avec: Max B Sauerland , Christina Helm , Lasse G Lorentzen , Asmita Manandhar , Trond Ulven , Luke F Gamon , Michael J Davies

Discovery of Potent Tetrazole Free Fatty Acid Receptor 2 Antagonists.

Journal of medicinal chemistry

Avec: Alice Valentini , Katrine Schultz-Knudsen , Anders Højgaard Hansen , Argyro Tsakoumagkou , Laura Jenkins , Henriette B Christensen , Asmita Manandhar , Graeme Milligan , Trond Ulven , Elisabeth Rexen Ulven

Drug Repurposing in Crohn's Disease Using Danish Real-World Data.

Pragmatic and observational research

Avec: Saeed Shakibfar , Kristine H Allin , Tine Jess , Maria Antonietta Barbieri , Vera Battini , Eva Simoncic , Julien Kirchgesner , Trond Ulven , Maurizio Sessa

Réseau de co-auteurs

Elisabeth Rexen Ulven 10 collaborations

Graeme Milligan 7 collaborations

Asmita Manandhar 5 collaborations

Mads H Kaspersen 4 collaborations

Jeppe H Ekberg 3 collaborations

Andrew B Tobin 3 collaborations

Loukas Ieremias 3 collaborations

Laura Jenkins 3 collaborations

Brian D Hudson 3 collaborations

Mette M Rosenkilde 3 collaborations

Katrine Schultz-Knudsen 3 collaborations

Anders Højgaard Hansen 3 collaborations

Karina V Sørensen 2 collaborations

Annette Bauer-Brandl 2 collaborations

Kurt Højlund 2 collaborations

Luke F Gamon 2 collaborations

Michael J Davies 2 collaborations

Estela Lorza-Gil 2 collaborations

Gabriele Kaiser 2 collaborations

Gabriele M König 2 collaborations

Evi Kostenis 2 collaborations

Andreas L Birkenfeld 2 collaborations

Hans-Ulrich Häring 2 collaborations

Susanne Ullrich 2 collaborations

Felicia Gerst 2 collaborations

Hans Bräuner-Osborne 2 collaborations

Natasja Barki 2 collaborations

Viktorija Daugvilaite 2 collaborations

Athanasios Papangelis 2 collaborations

Licio A Velloso 2 collaborations

Eugenia Sergeev 2 collaborations

Matjaz Brvar 2 collaborations

Michael Lückmann 2 collaborations

Thomas M Frimurer 2 collaborations

Henriette B Christensen 2 collaborations

Alice Valentini 2 collaborations

Valentin Sencio 1 collaboration

Adeline Barthelemy 1 collaboration

Luciana P Tavares 1 collaboration

Marina G Machado 1 collaboration

Daphnée Soulard 1 collaboration

Céline Cuinat 1 collaboration

Celso Martins Queiroz-Junior 1 collaboration

Marie-Louise Noordine 1 collaboration

Sophie Salomé-Desnoulez 1 collaboration

Lucie Deryuter 1 collaboration

Benoit Foligné 1 collaboration

Céline Wahl 1 collaboration

Benoit Frisch 1 collaboration

Angelica T Vieira 1 collaboration

Christophe Paget 1 collaboration

Isabelle Wolowczuk 1 collaboration

Christelle Faveeuw 1 collaboration

Ronan Le Goffic 1 collaboration

Muriel Thomas 1 collaboration

Stéphanie Ferreira 1 collaboration

Mauro M Teixeira 1 collaboration

François Trottein 1 collaboration

Rudi Prihandoko 1 collaboration

Davinder Kaur 1 collaboration

Coen H Wiegman 1 collaboration

Elisa Alvarez-Curto 1 collaboration

Chantal Donovan 1 collaboration

Latifa Chachi 1 collaboration

Martha R Tyas 1 collaboration

Eloise Euston 1 collaboration

Zhaoyang Dong 1 collaboration

Abdulrahman Ghali M Alharbi 1 collaboration

Richard Y Kim 1 collaboration

Jack G Lowe 1 collaboration

Philip M Hansbro 1 collaboration

Kian Fan Chung 1 collaboration

Christopher E Brightling 1 collaboration

Meryem Köse 1 collaboration

Thanigaimalai Pillaiyar 1 collaboration

Vigneshwaran Namasivayam 1 collaboration

Elisabetta De Filippo 1 collaboration

Katharina Sylvester 1 collaboration

Ivar von Kügelgen 1 collaboration

Christa E Müller 1 collaboration

Jonas Mårtensson 1 collaboration

Martina Sundqvist 1 collaboration

Linjie Zhang 1 collaboration

Xin Xie 1 collaboration

Lena Björkman 1 collaboration

Huamei Forsman 1 collaboration

Chiara Morozzi 1 collaboration

Max Sauerland 1 collaboration

Christopher Carlein 1 collaboration

Markus D A Hoffmann 1 collaboration

Sieglinde Haug 1 collaboration

Leticia Prates Roma 1 collaboration

Yufang Deng 1 collaboration

Claudia V Perez Almeria 1 collaboration

Lieke van Gijzel 1 collaboration

Kay Schaller 1 collaboration

Line Vedel 1 collaboration

David E Gloriam 1 collaboration

Edward T Wargent 1 collaboration

Małgorzata A Kępczyńska 1 collaboration

Jonathan R S Arch 1 collaboration

Claire J Stocker 1 collaboration

Svend S Korfitzen 1 collaboration

Babar Murtaza 1 collaboration

Aziz Hichami 1 collaboration

Amira S Khan 1 collaboration

Bharat Shimpukade 1 collaboration

Mehmet Hakan Ozdener 1 collaboration

Naim A Khan 1 collaboration

Daniele Bolognini 1 collaboration

Ulf Börjesson 1 collaboration

John Riddell 1 collaboration

David I Hughes 1 collaboration

Niek Dekker 1 collaboration

Viktoria M S Kjær 1 collaboration

Tomasz M Stepniewski 1 collaboration

Christian M Madsen 1 collaboration

Astrid S Jørgensen 1 collaboration

Kaustubh R Bhuskute 1 collaboration

Asuka Inoue 1 collaboration

Tau Benned-Jensen 1 collaboration

Siv A Hjorth 1 collaboration

Gertrud M Hjortø 1 collaboration

Ee Von Moo 1 collaboration

Jana Selent 1 collaboration

Christina Ioanna Vrettou 1 collaboration

Rina Pokhrel 1 collaboration

Christoffer V Heidtmann 1 collaboration

Christina Kanellou 1 collaboration

Sara Marsango 1 collaboration

Yueming Li 1 collaboration

Daiane F Engel 1 collaboration

Vanessa C D Bobbo 1 collaboration

Carina S Solon 1 collaboration

Guilherme A Nogueira 1 collaboration

Alexandre Moura-Assis 1 collaboration

Natalia F Mendes 1 collaboration

Ariane M Zanesco 1 collaboration

Tezz Quon 1 collaboration

Palash Dutta 1 collaboration

Line Ø Bielefeldt 1 collaboration

Christine J McKenzie 1 collaboration

Anna Sofie Husted 1 collaboration

Emma Tripp 1 collaboration

Tinne A D Nissen 1 collaboration

Stijn Meijnikman 1 collaboration

Shannon L O'Brien 1 collaboration

Yair Acherman 1 collaboration

Sjoerd C Bruin 1 collaboration

Max Nieuwdorp 1 collaboration

Zach Gerhart-Hines 1 collaboration

Davide Calebiro 1 collaboration

Lars O Dragsted 1 collaboration

Thue W Schwartz 1 collaboration

Ruwei Yao 1 collaboration

Anders A Jensen 1 collaboration

Hogan P Bryce-Rogers 1 collaboration

Libin Zhou 1 collaboration

Nicklas P Hovendal 1 collaboration

Henrik Pedersen 1 collaboration

Mariusz Kubus 1 collaboration

Luca Laraia 1 collaboration

Dmitrii V Kalinin 1 collaboration

Olav Larsen 1 collaboration

Wijnand J C van der Velden 1 collaboration

Marta Oliva-Santiago 1 collaboration

Stefanie Karlshøj 1 collaboration

Anna Theiler 1 collaboration

Thomas Bärnthaler 1 collaboration

Wolfgang Platzer 1 collaboration

Georg Richtig 1 collaboration

Miriam Peinhaupt 1 collaboration

Sonja Rittchen 1 collaboration

Julia Kargl 1 collaboration

Leigh M Marsh 1 collaboration

Gunther Marsche 1 collaboration

Rufina Schuligoi 1 collaboration

Eva M Sturm 1 collaboration

Akos Heinemann 1 collaboration

Sunil K Pandey 1 collaboration

Julia Dunlop 1 collaboration

Domonkos Dedeo 1 collaboration

Simone Fratta 1 collaboration

Morgana Barroso Oquendo 1 collaboration

Viktoria M S Kjaer 1 collaboration

Jon Våbenø 1 collaboration

Nathalia R V Dragano 1 collaboration

Edward Milbank 1 collaboration

Roberta Haddad-Tóvolli 1 collaboration

Pablo Garrido-Gil 1 collaboration

Eva Nóvoa 1 collaboration

Marcos F Fondevilla 1 collaboration

Valentina Capelli 1 collaboration

Ariane Maria Zanesco 1 collaboration

Carina Solon 1 collaboration

Joseane Morari 1 collaboration

Leticia Pires 1 collaboration

Ánxela Estevez-Salguero 1 collaboration

Daniel Beiroa 1 collaboration

Ismael González-García 1 collaboration

Olga Barca-Mayo 1 collaboration

Carlos Diéguez 1 collaboration

Ruben Nogueiras 1 collaboration

José L Labandeira-García 1 collaboration

Marc Claret 1 collaboration

Miguel Lopez 1 collaboration

Max B Sauerland 1 collaboration

Christina Helm 1 collaboration

Lasse G Lorentzen 1 collaboration

Argyro Tsakoumagkou 1 collaboration

Saeed Shakibfar 1 collaboration

Kristine H Allin 1 collaboration

Tine Jess 1 collaboration

Maria Antonietta Barbieri 1 collaboration

Vera Battini 1 collaboration

Eva Simoncic 1 collaboration

Julien Kirchgesner 1 collaboration

Maurizio Sessa 1 collaboration