questionsmedicales.fr
Métabolisme
Désalkylation
Déméthylation
Déméthylation : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Déméthylation
Analyse de l'ADN
Marqueurs épigénétiques
5-méthylcytosine
Tests sanguins
ADN circulant
Biopsie
Analyse tissulaire
Troubles neurologiques
Cancers
Symptômes
5
Troubles cognitifs
Anomalies de croissance
Maladies génétiques
Cancer
Changements de comportement
Anomalies physiques
Système immunitaire
Infections
Prévention
5
Alimentation équilibrée
Mode de vie sain
Suppléments
Acide folique
Exercice physique
Santé épigénétique
Toxines environnementales
Perturbation épigénétique
Traitements
5
Thérapie génique
Médicaments ciblés
Thérapies épigénétiques
Cancer
Médecine personnalisée
Profil génétique
Complications
5
Cancers
Maladies auto-immunes
Réversibilité
Modifications épigénétiques
Maladies chroniques
Troubles de développement
Fertilité
Fonction reproductive
Effets à long terme
Prédispositions
Facteurs de risque
5
Facteurs de risque
Toxines
Hérédité
Facteurs génétiques
Maladies chroniques
Risque
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"description": "Comment diagnostiquer une déméthylation anormale ?\nQuels marqueurs sont utilisés pour la déméthylation ?\nQuels tests sanguins peuvent indiquer une déméthylation ?\nLa biopsie est-elle nécessaire pour diagnostiquer la déméthylation ?\nQuels symptômes peuvent alerter sur une déméthylation ?",
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"text": "Des tests génétiques et des analyses de l'ADN peuvent révéler des modifications de méthylation."
}
},
{
"@type": "Question",
"name": "Quels marqueurs sont utilisés pour la déméthylation ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les marqueurs épigénétiques comme 5-méthylcytosine sont souvent analysés."
}
},
{
"@type": "Question",
"name": "Quels tests sanguins peuvent indiquer une déméthylation ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests de métabolites et d'ADN circulant peuvent fournir des indices."
}
},
{
"@type": "Question",
"name": "La biopsie est-elle nécessaire pour diagnostiquer la déméthylation ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une biopsie peut être nécessaire pour des analyses plus précises des tissus."
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{
"@type": "Question",
"name": "Quels symptômes peuvent alerter sur une déméthylation ?",
"position": 5,
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{
"@type": "Question",
"name": "Quels symptômes sont associés à la déméthylation ?",
"position": 6,
"acceptedAnswer": {
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{
"@type": "Question",
"name": "La déméthylation peut-elle causer des maladies ?",
"position": 7,
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{
"@type": "Question",
"name": "Y a-t-il des signes cliniques de déméthylation ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes cliniques peuvent inclure des changements de comportement et des anomalies physiques."
}
},
{
"@type": "Question",
"name": "Les symptômes varient-ils selon l'âge ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes peuvent se manifester différemment selon l'âge et le développement."
}
},
{
"@type": "Question",
"name": "La déméthylation affecte-t-elle le système immunitaire ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut altérer la réponse immunitaire, augmentant le risque d'infections."
}
},
{
"@type": "Question",
"name": "Comment prévenir la déméthylation ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée et un mode de vie sain peuvent aider à prévenir la déméthylation."
}
},
{
"@type": "Question",
"name": "Les suppléments peuvent-ils aider ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des suppléments comme l'acide folique peuvent soutenir la méthylation."
}
},
{
"@type": "Question",
"name": "Le stress influence-t-il la déméthylation ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut affecter les mécanismes de méthylation."
}
},
{
"@type": "Question",
"name": "L'exercice physique a-t-il un impact ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'exercice régulier peut améliorer la santé épigénétique et la méthylation."
}
},
{
"@type": "Question",
"name": "Les toxines environnementales jouent-elles un rôle ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à certaines toxines peut perturber les mécanismes de méthylation."
}
},
{
"@type": "Question",
"name": "Quels traitements existent pour la déméthylation ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des thérapies géniques et des médicaments ciblés."
}
},
{
"@type": "Question",
"name": "La nutrition peut-elle influencer la déméthylation ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains nutriments comme l'acide folique peuvent moduler la méthylation."
}
},
{
"@type": "Question",
"name": "Les thérapies épigénétiques sont-elles efficaces ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles montrent un potentiel prometteur dans le traitement de certains cancers."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir la déméthylation par des médicaments ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des inhibiteurs spécifiques peuvent être utilisés pour prévenir la déméthylation."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils personnalisés ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements peuvent être adaptés en fonction du profil génétique du patient."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des cancers, des troubles neurologiques et des maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "La déméthylation est-elle réversible ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines modifications peuvent être réversibles, mais pas toutes."
}
},
{
"@type": "Question",
"name": "Quels risques sont associés à la déméthylation ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les risques incluent des maladies chroniques et des troubles de développement."
}
},
{
"@type": "Question",
"name": "La déméthylation peut-elle affecter la fertilité ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut influencer la fertilité en altérant la fonction reproductive."
}
},
{
"@type": "Question",
"name": "Y a-t-il des effets à long terme ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des effets à long terme peuvent inclure des prédispositions à diverses maladies."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque de déméthylation ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'alimentation, le stress, et l'exposition à des toxines."
}
},
{
"@type": "Question",
"name": "L'hérédité joue-t-elle un rôle ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des facteurs génétiques peuvent influencer la déméthylation."
}
},
{
"@type": "Question",
"name": "Les maladies chroniques augmentent-elles le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies chroniques peuvent augmenter le risque de déméthylation."
}
},
{
"@type": "Question",
"name": "Le mode de vie influence-t-il la déméthylation ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie malsain peut favoriser la déméthylation."
}
},
{
"@type": "Question",
"name": "Les infections peuvent-elles affecter la déméthylation ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections peuvent perturber les mécanismes de méthylation."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 19/04/2025
Contenu vérifié selon les dernières recommandations médicales
2 publications dans cette catégorie
Affiliations :
Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, Australia.
St. Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia.
School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney 22, Australia.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Genomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, Australia.
School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney 22, Australia.
Centro Andaluz de Biología del Desarrollo, CSIC-Universidad Pablo de Olavide-Junta de Andalucía, Seville, Spain.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Department of Environmental Sciences, University of California, Riverside, California 92521, United States.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Department of Environmental Sciences, University of California, Riverside, California 92521, United States.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Department of Environmental Sciences, University of California, Riverside, California 92521, United States.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Department of Environmental Sciences, University of California, Riverside, California 92521, United States.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Genetics, Stem Cells, Department of Cell and Molecular Biology, Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, 1983963113, Iran.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Genetics, Stem Cells, Department of Cell and Molecular Biology, Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, 1983963113, Iran. Electronic address: s_farivar@sbu.ac.ir.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Jiangsu Key Laboratory of TCM Evaluation and Translational Research, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, Jiangsu, China.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Jiangsu Key Laboratory of TCM Evaluation and Translational Research, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, Jiangsu, China. liujihua@cpu.edu.cn.
State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, Jiangsu, China. liujihua@cpu.edu.cn.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Department of Plant Science, Research Institute for Agriculture and Life Sciences, and Plant Genomics and Breeding Institute, Seoul National University, Seoul 08826, Korea.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Department of Plant Science, Research Institute for Agriculture and Life Sciences, and Plant Genomics and Breeding Institute, Seoul National University, Seoul 08826, Korea huhjh@snu.ac.kr.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115 USA.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115 USA.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.
Publications dans "Déméthylation" :
2 publications dans cette catégorie
Affiliations :
Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Publications dans "Déméthylation" :
Ultrasound of the elbow can be incorporated into routine pediatric practice in the radiology department, emergency department, orthopedic clinic, and interventional suite. Ultrasound is complementary ...
We aim to asses the diagnostic performance of ankle ultrasonography in patients presenting with acute ankle sprain injury, with comparison to MRI (Manyetik Rezonans İmaging)....
The study included patients who applied to the hospital within 48 h after an ankle sprain, and who presented with signs of pain, swelling, and tenderness in the ankle. Ankle ultrasonography examinatio...
30 patients were included in the study. 53.3% (n = 16) were female. The mean age was 30 ± 6.4 years. The ultrasonography examination determined 76.6% (n = 23) of the patients to have anterior talofibu...
Findings on all types of ATFL, CFL and AITFL appear to have a higher degree of correlation. Ultrasonography could have an added role as a triaging tool, to fast-track MRI....
We aimed to evaluate ultrasonography (US), colour Doppler US (CDUS) and sonoelastography (SEL) findings of histopathologically proven abdominal wall scar endometriosis in comparison with menstrual pha...
Artificial intelligence (AI) continues to change paradigms in the field of medicine with new applications that are applicable to daily life. The field of ultrasonography, which has been developing sin...
Ultrasonography is an imaging technique based on sound waves used for the evaluation of soft tissues. Sound waves have been used for a long time in nonmedical fields, including military defense system...
Rapid diagnostic tools available to the emergency physician caring for cardiac arrest patients are limited. Focused ultrasound (US), and in particular, focused echocardiography, is a useful tool in th...
This case image demonstrates the usefulness of vulvar ultrasound in the diagnosis of vulvar abscess....
Levator ani defect (LAD) closely correlates with pelvic floor disorders (PFD). In general, LAD was graded by three-dimensional ultrasonography (3D-US) and MRI, which could be used hardly in some devel...
Chronic trigonitis (CT) is usually diagnosed through cystoscopy which is invasive and expensive. Thus, an accurate non-invasive diagnostic method is necessary. The objective of this study is to determ...
Between 2012 and 2021, 114 women (17-76 years old) with recurrent urinary tract infection (RUTI) and history of antibiotic resistance were evaluated with TBU by a single ultrasonographer. As a control...
Thickening of trigone mucosa (>3 mm) was detected in all patients with RUTI and represented the most relevant criteria for trigonitis diagnosis on TBU. Other TBU findings in CT are: irregular and inte...
TBU proved to be an efficient, inexpensive and minimally invasive method to diagnose CT. To our knowledge, this is the first article that reports the use of transvaginal ultrasound as an alternative m...
Gastric tubes are commonly used for the administration of drugs and tube feeding for people who are unable to swallow. Feeding via a tube misplaced in the trachea can result in severe pneumonia. There...
To assess the diagnostic accuracy of ultrasound alone or in combination with other methods for gastric tube placement confirmation in children and adults....
This systematic review is an update of a previously published Cochrane review. For this update, we searched the Cochrane Library (2021, Issue 6), MEDLINE (to April 2023), Embase (to April 2023), five ...
We included studies that evaluated the diagnostic accuracy of naso- and orogastric tube placement confirmed by ultrasound visualization using X-ray visualization as the reference standard. We included...
Two review authors independently assessed the methodological quality and extracted data from each of the included studies. We contacted the authors of the included studies to obtain missing data. Ther...
We identified 12 new studies in addition to 10 studies included in the earlier version of this review, totalling 1939 participants and 1944 tube insertions. Overall, we judged the risk of bias in the ...
Of 22 studies that assessed the diagnostic accuracy of gastric tube placement, few studies had a low risk of bias. Based on limited evidence, ultrasound does not have sufficient accuracy as a single t...