Les maladies métaboliques augmentent-elles le risque ?
Certaines maladies métaboliques peuvent être associées à des anomalies de glycosylation.
Maladies métaboliquesGlycosylation
#5
Le sexe a-t-il un impact sur la glycosylation ?
Oui, certaines anomalies peuvent avoir des manifestations différentes selon le sexe.
SexeAnomalies de glycosylation
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"position": 4,
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"@type": "Question",
"name": "La fatigue est-elle un symptôme de glycosylation ?",
"position": 7,
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"text": "Oui, la fatigue peut être un symptôme associé à des troubles de glycosylation."
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"name": "Les troubles digestifs sont-ils liés à la glycosylation ?",
"position": 8,
"acceptedAnswer": {
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"text": "Oui, certains troubles digestifs peuvent être liés à des anomalies de glycosylation."
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"position": 14,
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"name": "Quels traitements existent pour les anomalies de glycosylation ?",
"position": 16,
"acceptedAnswer": {
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"text": "Les traitements incluent des thérapies de soutien et des interventions spécifiques selon les symptômes."
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"name": "Les enzymes de remplacement sont-elles efficaces ?",
"position": 17,
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"name": "La diététique joue-t-elle un rôle dans le traitement ?",
"position": 18,
"acceptedAnswer": {
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"text": "Oui, des régimes spécifiques peuvent aider à gérer certains symptômes."
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"@type": "Question",
"name": "Les médicaments immunosuppresseurs sont-ils utilisés ?",
"position": 19,
"acceptedAnswer": {
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"text": "Ils peuvent être prescrits pour traiter des complications immunitaires."
}
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{
"@type": "Question",
"name": "Y a-t-il des traitements expérimentaux disponibles ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des essais cliniques sont en cours pour de nouvelles thérapies ciblées."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles de la glycosylation ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des troubles neurologiques, des infections et des problèmes de croissance."
}
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{
"@type": "Question",
"name": "Les infections sont-elles fréquentes chez ces patients ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients peuvent être plus susceptibles aux infections en raison d'un système immunitaire affaibli."
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{
"@type": "Question",
"name": "Y a-t-il des risques de cancer associés ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines anomalies de glycosylation peuvent augmenter le risque de cancers spécifiques."
}
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{
"@type": "Question",
"name": "Les troubles cardiovasculaires sont-ils liés ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles cardiovasculaires peuvent survenir chez certains patients."
}
},
{
"@type": "Question",
"name": "Les complications psychologiques sont-elles possibles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des complications psychologiques comme l'anxiété peuvent être observées."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour les anomalies de glycosylation ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux et certaines mutations génétiques sont des facteurs de risque."
}
},
{
"@type": "Question",
"name": "L'âge joue-t-il un rôle dans la glycosylation ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines anomalies peuvent se manifester plus tôt dans l'enfance, mais d'autres plus tard."
}
},
{
"@type": "Question",
"name": "Les facteurs environnementaux influencent-ils la glycosylation ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des facteurs environnementaux peuvent interagir avec des prédispositions génétiques."
}
},
{
"@type": "Question",
"name": "Les maladies métaboliques augmentent-elles le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies métaboliques peuvent être associées à des anomalies de glycosylation."
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{
"@type": "Question",
"name": "Le sexe a-t-il un impact sur la glycosylation ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines anomalies peuvent avoir des manifestations différentes selon le sexe."
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Department of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan University, No. 17 Renmin Nan Road, Chengdu, 610041, China.
Department of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan University, No. 17 Renmin Nan Road, Chengdu, 610041, China.
Department of Chemistry, Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka 560-0043, Japan.
Core for Medicine and Science Collaborative Research and Education Project Research Center for Fundamental Sciences Graduate School of Science Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka 560-0043, Japan.
Department of Neurology, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Centre, Geert Grooteplein 10, 6525 GA Nijmegen, The Netherlands.
Department of Laboratory Medicine, Translational Metabolic Laboratory, Radboud University Medical Center, Geert Grooteplein 10, 6525 GA Nijmegen, The Netherlands.
Department of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan University, No. 17 Renmin Nan Road, Chengdu, 610041, China.
Department of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan University, No. 17 Renmin Nan Road, Chengdu, 610041, China.
Department of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan University, No. 17 Renmin Nan Road, Chengdu, 610041, China.
State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, PR China. Electronic address: 459856454@qq.com.
Embryo transfer(ET) is one of the main procedures to become pregnant by assisted reproductive technology(ART). Simulation training is a way to improve the skills of clinicians. The objective of this s...
An observational study was conducted at the University hospital-based research center. Trainees, comprising midwives and resident or graduated gynecologists, who attended the medical training for infe...
Thirty-two trainees were included. Trainees felt that ET simulators should be used in medical education to promote learning how to perform the ET procedure (n=26, 81.3% for Simulator A and n=21, 65.5%...
Students expressed a high level of interest in ET simulators to improve their skills. Although the simulators displayed some differences regarding learning the precision of the ET procedure, both impr...
This study was approved for publication by the Ethics Review Committee of the Cochin University Hospital (CLEP) (n° AAA-2020-08016) retrospectively registered....
This study compared the pregnancy and neonatal outcomes between fresh embryo transfer and frozen-thawed embryo transfer (FET). These patients were split into two groups: the fresh embryo transfer grou...
Recurrent implantation failure (RIF) is more common among patients receiving assisted reproductive treatment. Many efforts have been made to increase the incidence of clinical pregnancy among patients...
In total, 1774 frozen-thawed embryo transfer (FET) cycles in RIF patients were included. Of these cycles, 302 were sequential embryo transfer (ET) cycles, 979 were double day 3 cleavage-stage ET cycle...
The implantation, hCG positive, and clinical pregnancy rates in the sequential ET group (32.1%, 58.9%, 50.7%) were significantly higher than those in the day 3 cleavage-stage ET group (24.9%, 46.5%, 4...
Sequential embryo transfer in FET cycles could improve the clinical outcomes of patients with RIF....
Embryo transfer (ET) is considered as a critical step in the process of in vitro fertilization. Interestingly, studies have consistently shown significant outcome differences between physicians. Altho...
The process of implantation is characterized by a complex cross-talk between the endometrium and the blastocyst, with the endometrium only being receptive to implantation during a transient window of ...
Physicians need an appropriate embryo transfer strategy to address the challenge of reducing multiple birth rates, while maintaining the couples' live birth rate during assisted reproductive technolog...
We included 10,060 frozen embryo transfer cycles from January 2015 to March 2020 in reproductive medical center of Ruijin hospital, Shanghai, China. Patients were grouped according to the number and g...
The transfer of double good-quality embryos was an independent predictor for multiple birth in women aged <30 years and those aged 36-39 years [<30 years: aOR =1.54 (95% CI: 1.14-2.06, P < 0.01); 36-3...
Single-good-quality blastocyst transfer is recommended for women of all ages. When good-quality cleavage embryos are available, the choice of single or double embryo transfer with good- or average-qua...
To investigate the effects of fresh embryo transfer and frozen-thawed embryo transfer on perinatal outcomes among patients with PCOS....
Patients who underwent in vitro fertilization and embryo transfer at the reproductive medicine center of the Affiliated Hospital of Guangdong Medical University from February 2013 to March 2021 were r...
The level of E2 on the HCG test day in the ET group was lower than that in the FET group. The natural birth rate of group D was lower than that of group A and group B, and the cesarean section rate wa...
Young PCOS patients without risk of OHSS have a high clinical pregnancy rate with fresh transplant cycles. PCOS disease itself has no significant effect on the perinatal outcomes of the mother or sing...
After an assisted reproductive technology (ART) cycle, embryo transfer (ET) involves the placement of one or more embryos into the uterine cavity, usually by passing a catheter through the cervical os...
To evaluate the benefits and harms of antibiotic administration prior to or at the time of embryo transfer (ET) during assisted reproductive technology (ART) cycles....
We searched the Cochrane Gynaecology and Fertility (CGF) Group trials register, CENTRAL (now containing output from two trial registers and CINAHL), MEDLINE, Embase and PsycINFO, together with referen...
We included two randomized controlled trials (RCT) that compared antibiotics administered by any route versus no antibiotics prior to ET....
We used standard methodological procedures recommended by Cochrane, including assessing risk of bias of the included studies using the RoB 2 tool. The primary review outcome was live birth rate (LBR) ...
We included two RCTs with 377 women in the review. Using the GRADE method, we assessed the certainty of the evidence as very low to low across measured outcomes. We are uncertain whether antibiotics g...
We are uncertain if administration of antibiotics prior to or at the time of ET improves LBR in women undergoing ART based on a single study of 27 women with low-certainty evidence. We are uncertain w...
This study aims to investigate the factors affecting the ectopic pregnancy (EP) rate in the frozen-thawed embryo transfer (FET) cycle....
This study retrospectively analyzed 5606 FET cycles, including 5496 cycles resulting in intrauterine pregnancy and 110 cycles resulting in EP. Smooth curve fitting and piece-wise linear regression wer...
After accounting for the confounding factors, the segmented linear regression analysis indicated that the EMT inflection point was 9 mm; the EP rate significantly decreased by 28% with each additional...
Undergoing EMT on the day of ET poses a separate EP risk in the FET cycle; to mitigate the EP incidence, the EMT should exceed 9 mm before ET. Furthermore, previous EPs and tubal factor infertility we...
To compare clinical outcomes following transfer of euploid blastocysts of varying quality biopsied on day 5 versus day 6....
Retrospective cohort study to evaluate embryo transfer outcomes for women undergoing autologous cryopreserved next generation sequencing euploid single embryo transfer from 10/2015 to 2/2022 at an aca...
Five hundred and fifty-five transfers from 418 patients were analyzed. Euploid embryos biopsied on day 5 resulted in higher LBR compared to those biopsied on day 6 (62.3% vs. 49.6%; aRR 0.81 95% CI 0....
Overall LBR are higher for euploid embryos biopsied on day 5 versus day 6. When stratified by embryo quality and day of biopsy, LBR are significantly higher for good quality day 5 versus day 6 embryos...