questionsmedicales.fr
Métabolisme
Métabolisme glucidique
Glycosylation
Glycosylation : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Glycosylation
Tests génétiques
Glycoprotéines
Tests sanguins
Anomalies congénitales
Développement
Imagerie médicale
Complications
Symptômes
5
Troubles neurologiques
Infections
Troubles digestifs
Glycosylation
Éruptions cutanées
Anomalies de la peau
Retard de croissance
Glycosylation
Prévention
5
Prévention
Diagnostic précoce
Dépistage génétique
Antécédents familiaux
Alimentation équilibrée
Système immunitaire
Consultations médicales
Surveillance
Traitements
5
Thérapies de soutien
Interventions médicales
Enzymes de remplacement
Maladies métaboliques
Diététique
Gestion des symptômes
Médicaments immunosuppresseurs
Complications immunitaires
Essais cliniques
Thérapies ciblées
Complications
5
Complications
Troubles neurologiques
Infections
Système immunitaire
Cancer
Anomalies de glycosylation
Troubles cardiovasculaires
Glycosylation
Complications psychologiques
Anxiété
Facteurs de risque
5
Antécédents familiaux
Mutations génétiques
Âge
Anomalies congénitales
Facteurs environnementaux
Prédispositions génétiques
Maladies métaboliques
Glycosylation
Sexe
Anomalies de glycosylation
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Glycosylation : Questions médicales les plus fréquentes",
"headline": "Glycosylation : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Glycosylation : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-05-04",
"dateModified": "2025-04-29",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Glycosylation"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Métabolisme glucidique",
"url": "https://questionsmedicales.fr/mesh/D050260",
"about": {
"@type": "MedicalCondition",
"name": "Métabolisme glucidique",
"code": {
"@type": "MedicalCode",
"code": "D050260",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "G03.191"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Glycosylation",
"alternateName": "Glycosylation",
"code": {
"@type": "MedicalCode",
"code": "D006031",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Christian Marcus Pedersen",
"url": "https://questionsmedicales.fr/author/Christian%20Marcus%20Pedersen",
"affiliation": {
"@type": "Organization",
"name": "Department of Chemistry, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen Ø, Denmark."
}
},
{
"@type": "Person",
"name": "Yanjing Li",
"url": "https://questionsmedicales.fr/author/Yanjing%20Li",
"affiliation": {
"@type": "Organization",
"name": "Department of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan University, No. 17 Renmin Nan Road, Chengdu, 610041, China."
}
},
{
"@type": "Person",
"name": "Dawen Niu",
"url": "https://questionsmedicales.fr/author/Dawen%20Niu",
"affiliation": {
"@type": "Organization",
"name": "Department of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan University, No. 17 Renmin Nan Road, Chengdu, 610041, China."
}
},
{
"@type": "Person",
"name": "Liang Yang",
"url": "https://questionsmedicales.fr/author/Liang%20Yang",
"affiliation": {
"@type": "Organization",
"name": "Department of Chemistry, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen Ø, Denmark."
}
},
{
"@type": "Person",
"name": "Boon Chong Lee",
"url": "https://questionsmedicales.fr/author/Boon%20Chong%20Lee",
"affiliation": {
"@type": "Organization",
"name": "Department of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore, 117544, Republic of Singapore."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Tabletability and compactibility of",
"datePublished": "2023-06-13",
"url": "https://questionsmedicales.fr/article/37310086",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1080/10837450.2023.2214614"
}
},
{
"@type": "ScholarlyArticle",
"name": "Effect of tableting temperature on tablet properties and dissolution behavior of heat sensitive formulations.",
"datePublished": "2023-11-13",
"url": "https://questionsmedicales.fr/article/37967689",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.ijpharm.2023.123603"
}
},
{
"@type": "ScholarlyArticle",
"name": "Single-tablet-scale direct-compression: An on-demand manufacturing route for personalized tablets.",
"datePublished": "2023-07-26",
"url": "https://questionsmedicales.fr/article/37507098",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.ijpharm.2023.123274"
}
},
{
"@type": "ScholarlyArticle",
"name": "Enhancing tabletability of high-dose tablets by tailoring properties of spray-dried insulin particles.",
"datePublished": "2022-12-21",
"url": "https://questionsmedicales.fr/article/36565770",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.ijpharm.2022.122526"
}
},
{
"@type": "ScholarlyArticle",
"name": "Pharmacokinetics and Bioequivalence of Mirogabalin Orally Disintegrating Tablets and Conventional Tablets in Healthy Japanese Participants.",
"datePublished": "2023-06-13",
"url": "https://questionsmedicales.fr/article/37312273",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1002/cpdd.1292"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Métabolisme",
"item": "https://questionsmedicales.fr/mesh/D008660"
},
{
"@type": "ListItem",
"position": 3,
"name": "Métabolisme glucidique",
"item": "https://questionsmedicales.fr/mesh/D050260"
},
{
"@type": "ListItem",
"position": 4,
"name": "Glycosylation",
"item": "https://questionsmedicales.fr/mesh/D006031"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Glycosylation - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Glycosylation",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-03",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Glycosylation",
"description": "Comment diagnostiquer une anomalie de glycosylation ?\nQuels tests sanguins sont utilisés pour la glycosylation ?\nLes biopsies sont-elles utiles pour la glycosylation ?\nQuels symptômes indiquent une anomalie de glycosylation ?\nPeut-on utiliser l'imagerie pour diagnostiquer la glycosylation ?",
"url": "https://questionsmedicales.fr/mesh/D006031?mesh_terms=Tablets#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Glycosylation",
"description": "Quels sont les symptômes d'une glycosylation anormale ?\nLa fatigue est-elle un symptôme de glycosylation ?\nLes troubles digestifs sont-ils liés à la glycosylation ?\nY a-t-il des symptômes cutanés associés ?\nLes problèmes de croissance sont-ils fréquents ?",
"url": "https://questionsmedicales.fr/mesh/D006031?mesh_terms=Tablets#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Glycosylation",
"description": "Peut-on prévenir les anomalies de glycosylation ?\nLe dépistage génétique est-il recommandé ?\nLes vaccinations aident-elles à prévenir les complications ?\nY a-t-il des conseils diététiques préventifs ?\nLes consultations médicales régulières sont-elles importantes ?",
"url": "https://questionsmedicales.fr/mesh/D006031?mesh_terms=Tablets#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Glycosylation",
"description": "Quels traitements existent pour les anomalies de glycosylation ?\nLes enzymes de remplacement sont-elles efficaces ?\nLa diététique joue-t-elle un rôle dans le traitement ?\nLes médicaments immunosuppresseurs sont-ils utilisés ?\nY a-t-il des traitements expérimentaux disponibles ?",
"url": "https://questionsmedicales.fr/mesh/D006031?mesh_terms=Tablets#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Glycosylation",
"description": "Quelles sont les complications possibles de la glycosylation ?\nLes infections sont-elles fréquentes chez ces patients ?\nY a-t-il des risques de cancer associés ?\nLes troubles cardiovasculaires sont-ils liés ?\nLes complications psychologiques sont-elles possibles ?",
"url": "https://questionsmedicales.fr/mesh/D006031?mesh_terms=Tablets#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Glycosylation",
"description": "Quels sont les facteurs de risque pour les anomalies de glycosylation ?\nL'âge joue-t-il un rôle dans la glycosylation ?\nLes facteurs environnementaux influencent-ils la glycosylation ?\nLes maladies métaboliques augmentent-elles le risque ?\nLe sexe a-t-il un impact sur la glycosylation ?",
"url": "https://questionsmedicales.fr/mesh/D006031?mesh_terms=Tablets#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer une anomalie de glycosylation ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques et des analyses de glycoprotéines sont utilisés."
}
},
{
"@type": "Question",
"name": "Quels tests sanguins sont utilisés pour la glycosylation ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests de glycoprotéines et les profils glycosylés sont courants."
}
},
{
"@type": "Question",
"name": "Les biopsies sont-elles utiles pour la glycosylation ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les biopsies tissulaires peuvent révéler des anomalies de glycosylation."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent une anomalie de glycosylation ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des retards de développement, des problèmes immunitaires et des anomalies neurologiques."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser l'imagerie pour diagnostiquer la glycosylation ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'imagerie n'est pas spécifique, mais peut aider à évaluer des complications."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une glycosylation anormale ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent des troubles neurologiques, des infections fréquentes et des anomalies physiques."
}
},
{
"@type": "Question",
"name": "La fatigue est-elle un symptôme de glycosylation ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la fatigue peut être un symptôme associé à des troubles de glycosylation."
}
},
{
"@type": "Question",
"name": "Les troubles digestifs sont-ils liés à la glycosylation ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains troubles digestifs peuvent être liés à des anomalies de glycosylation."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes cutanés associés ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des éruptions cutanées et des anomalies de la peau peuvent survenir."
}
},
{
"@type": "Question",
"name": "Les problèmes de croissance sont-ils fréquents ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des retards de croissance peuvent être observés chez les patients affectés."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les anomalies de glycosylation ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention est difficile, mais un diagnostic précoce peut aider à gérer les symptômes."
}
},
{
"@type": "Question",
"name": "Le dépistage génétique est-il recommandé ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le dépistage génétique peut être utile pour les familles à risque."
}
},
{
"@type": "Question",
"name": "Les vaccinations aident-elles à prévenir les complications ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les vaccinations peuvent réduire le risque d'infections chez ces patients."
}
},
{
"@type": "Question",
"name": "Y a-t-il des conseils diététiques préventifs ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut soutenir la santé globale et le système immunitaire."
}
},
{
"@type": "Question",
"name": "Les consultations médicales régulières sont-elles importantes ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles permettent de surveiller l'évolution et d'ajuster les traitements."
}
},
{
"@type": "Question",
"name": "Quels traitements existent pour les anomalies de glycosylation ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des thérapies de soutien et des interventions spécifiques selon les symptômes."
}
},
{
"@type": "Question",
"name": "Les enzymes de remplacement sont-elles efficaces ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent être efficaces pour certaines formes de maladies liées à la glycosylation."
}
},
{
"@type": "Question",
"name": "La diététique joue-t-elle un rôle dans le traitement ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des régimes spécifiques peuvent aider à gérer certains symptômes."
}
},
{
"@type": "Question",
"name": "Les médicaments immunosuppresseurs sont-ils utilisés ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent être prescrits pour traiter des complications immunitaires."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements expérimentaux disponibles ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des essais cliniques sont en cours pour de nouvelles thérapies ciblées."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles de la glycosylation ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des troubles neurologiques, des infections et des problèmes de croissance."
}
},
{
"@type": "Question",
"name": "Les infections sont-elles fréquentes chez ces patients ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients peuvent être plus susceptibles aux infections en raison d'un système immunitaire affaibli."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de cancer associés ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines anomalies de glycosylation peuvent augmenter le risque de cancers spécifiques."
}
},
{
"@type": "Question",
"name": "Les troubles cardiovasculaires sont-ils liés ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles cardiovasculaires peuvent survenir chez certains patients."
}
},
{
"@type": "Question",
"name": "Les complications psychologiques sont-elles possibles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des complications psychologiques comme l'anxiété peuvent être observées."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour les anomalies de glycosylation ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux et certaines mutations génétiques sont des facteurs de risque."
}
},
{
"@type": "Question",
"name": "L'âge joue-t-il un rôle dans la glycosylation ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines anomalies peuvent se manifester plus tôt dans l'enfance, mais d'autres plus tard."
}
},
{
"@type": "Question",
"name": "Les facteurs environnementaux influencent-ils la glycosylation ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des facteurs environnementaux peuvent interagir avec des prédispositions génétiques."
}
},
{
"@type": "Question",
"name": "Les maladies métaboliques augmentent-elles le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies métaboliques peuvent être associées à des anomalies de glycosylation."
}
},
{
"@type": "Question",
"name": "Le sexe a-t-il un impact sur la glycosylation ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines anomalies peuvent avoir des manifestations différentes selon le sexe."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 29/04/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Department of Chemistry, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen Ø, Denmark.
Publications dans "Glycosylation" :
3 publications dans cette catégorie
Affiliations :
Department of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan University, No. 17 Renmin Nan Road, Chengdu, 610041, China.
Publications dans "Glycosylation" :
3 publications dans cette catégorie
Affiliations :
Department of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan University, No. 17 Renmin Nan Road, Chengdu, 610041, China.
Publications dans "Glycosylation" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen Ø, Denmark.
Publications dans "Glycosylation" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore, 117544, Republic of Singapore.
Publications dans "Glycosylation" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore, 117544, Republic of Singapore.
Publications dans "Glycosylation" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka 560-0043, Japan.
Core for Medicine and Science Collaborative Research and Education Project Research Center for Fundamental Sciences Graduate School of Science Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka 560-0043, Japan.
Publications dans "Glycosylation" :
2 publications dans cette catégorie
Affiliations :
Radboud University Institute for Molecules and Materials, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands. t.boltje@science.ru.nl.
Publications dans "Glycosylation" :
2 publications dans cette catégorie
Affiliations :
Center for Highly Advanced Integration of Nano and Life Sciences (G-CHAIN), Gifu University, Gifu, Japan. kizuka@gifu-u.ac.jp.
Institute for Glyco-core Research (iGCORE), Gifu University, Gifu, Japan. kizuka@gifu-u.ac.jp.
Publications dans "Glycosylation" :
2 publications dans cette catégorie
Affiliations :
Department of Neurology, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Centre, Geert Grooteplein 10, 6525 GA Nijmegen, The Netherlands.
Department of Laboratory Medicine, Translational Metabolic Laboratory, Radboud University Medical Center, Geert Grooteplein 10, 6525 GA Nijmegen, The Netherlands.
Publications dans "Glycosylation" :
2 publications dans cette catégorie
Affiliations :
Center for Proteomics and Metabolomics, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
Publications dans "Glycosylation" :
2 publications dans cette catégorie
Affiliations :
Department of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan University, No. 17 Renmin Nan Road, Chengdu, 610041, China.
Publications dans "Glycosylation" :
2 publications dans cette catégorie
Affiliations :
Department of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan University, No. 17 Renmin Nan Road, Chengdu, 610041, China.
Publications dans "Glycosylation" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Clinical Nuclear Medicine, Department of Nuclear Medicine, West China Hospital of Sichuan University, Chengdu, 610041, China.
Publications dans "Glycosylation" :
2 publications dans cette catégorie
Affiliations :
Department of Emergency, State Key Laboratory of Biotherapy, West China Hospital, and School of Chemical Engineering, Sichuan University, No. 17 Renmin Nan Road, Chengdu, 610041, China.
Publications dans "Glycosylation" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore, 117544, Republic of Singapore.
Publications dans "Glycosylation" :
2 publications dans cette catégorie
Affiliations :
School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, Queensland, Australia.
Publications dans "Glycosylation" :
2 publications dans cette catégorie
Affiliations :
University of Natural Resources and Life Sciences Vienna, Vienna, Austria. richard.strasser@boku.ac.at.
Publications dans "Glycosylation" :
1 publication dans cette catégorie
Affiliations :
Key Laboratory of Agriculture Biological Functional Gene of Heilongjiang Provincial Education Committee, Northeast Agricultural University, No. 600 Changjiang Road, Xiangfang District, Harbin, 150030, PR China.
Publications dans "Glycosylation" :
1 publication dans cette catégorie
Affiliations :
State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, PR China. Electronic address: 459856454@qq.com.
Publications dans "Glycosylation" :
This study aimed to evaluate a material sparing method to predict tabletability and compactibility relationships. Seven...
The tableting process involves the conversion of mechanical to thermal energy. This study evaluated the influence of temperature on the tableting behavior of formulations with different compositions. ...
Today's pharmaceutical industry is facing various challenges. Two of them are issues with supply chain security and the increasing demand for personalized medicine. Both can be addressed by increasing...
The oral delivery of proteins and peptides provides an attractive dosing option due to its high patient compliance. However, as oral formulations of such macromolecules require the addition of typical...
This single-center, randomized, open-label, single-dose, 2-group, 2-stage crossover trial evaluated the bioequivalence of 15 mg of mirogabalin as orally disintegrating tablets (ODTs) with conventional...
Mini-tablets are considered a promising solid dosage form in the pharmaceutical industry due to advantages such as dosing accuracy, efficiency as a drug delivery system, and alleged improvement in mec...
In this paper, the influence of powder properties and process parameters, such as punch shape and size, on the evolution of mechanical properties during the tableting process and the potential occurre...
The numerical simulation cases consist of four different die sizes, mini-tablets of 2 mm, and 3 mm, and conventionally sized tablets of 8 mm and 11.28 mm. Each tablet size is simulated using four dist...
The model predictions in terms of stress and density distribution at different stages of the compaction process indicate similar behavior in terms of density and stress distribution profiles between t...
Based on tablet size, small localized differences are noted (e.g., low-density regions, high shear bands, and heterogeneous density profiles), suggesting a possible risk of tableting defects for conve...
Predicting tablet defects, such as capping, that might occur during manufacturing, is a challenge in the pharmaceutical industry. In the literature, different parameters were presented to predict capp...
The plasticity of materials plays a critical role in adequate powder tabletability, which is required in developing a successful tablet product. Generally, a more plastic material can develop larger b...
Medication adherence can be challenging for persons with difficulty swallowing tablets. We investigated the bioequivalence of a dissolved tablet when compared with that of a whole tablet of the fixed-...
The effects of granule size of raw materials on tablet hardness (TH) and weight (TW) in the continuous tablet manufacturing process (CTMP) were investigated using near-infrared spectroscopy (NIRS)....
Granule materials of different sizes were prepared by extrusion granulation from a standard granule formula powder containing lactose/starch and 4.5% acetaminophen. Large-, small-, and medium-sized gr...
The best fitted calibration models for predicting TH and TW were obtained, with sufficient accuracy, based on NIRS using the partial least squares regression, and comprised both physical and chemical ...
The changes in the predicted value profiles of TH and TW using NIRS reflected the changes in the measured values depending on the raw granule size during CTMP....