Comment diagnostiquer une anémie?

Un test sanguin mesure le taux d'hémoglobine et d'hématocrite.

Quels tests pour les troubles de la coagulation?

Les tests de temps de prothrombine et de temps de thromboplastine partielle sont utilisés.

Comment détecter une leucémie?

Une analyse de sang et une biopsie de moelle osseuse sont nécessaires.

Quels signes indiquent une thrombocytopénie?

Des saignements faciles et des ecchymoses fréquentes peuvent indiquer une thrombocytopénie.

Quel rôle joue l'électrophorèse des protéines?

Elle aide à identifier les anomalies des protéines sanguines, comme dans le myélome.

Quels sont les symptômes d'une anémie?

Fatigue, pâleur, essoufflement et palpitations sont des symptômes courants.

Comment reconnaître une leucémie?

Symptômes incluent fièvre, fatigue, infections fréquentes et ecchymoses.

Quels signes d'une thrombose?

Douleur, gonflement et rougeur dans la zone affectée peuvent indiquer une thrombose.

Quels symptômes d'une polycythémie?

Rougeur de la peau, démangeaisons et maux de tête fréquents peuvent survenir.

Quels symptômes d'une infection sanguine?

Fièvre, frissons, confusion et fatigue intense sont des signes d'infection sanguine.

Comment prévenir l'anémie?

Une alimentation riche en fer et en vitamines est essentielle pour prévenir l'anémie.

Quelles mesures pour éviter les infections sanguines?

Maintenir une bonne hygiène et se faire vacciner aide à prévenir les infections.

Comment réduire le risque de thrombose?

Rester actif, éviter le tabac et maintenir un poids santé sont des mesures préventives.

Quelles précautions pour les patients leucémiques?

Éviter les foules et se laver fréquemment les mains pour prévenir les infections.

Comment prévenir la polycythémie?

Éviter le tabac et gérer les maladies sous-jacentes peut aider à prévenir la polycythémie.

Comment traiter l'anémie ferriprive?

Des suppléments de fer et des modifications alimentaires sont recommandés.

Quel traitement pour la leucémie?

Chimiothérapie, radiothérapie et greffe de moelle osseuse sont des options.

Comment traiter une thrombocytopénie?

Le traitement dépend de la cause; parfois, des transfusions plaquettaires sont nécessaires.

Quel traitement pour la polycythémie vera?

La phlébotomie et les médicaments pour réduire la production de globules rouges sont utilisés.

Comment gérer une infection sanguine?

Des antibiotiques intraveineux sont souvent nécessaires pour traiter l'infection.

Quelles complications de l'anémie?

Des complications peuvent inclure des problèmes cardiaques et des troubles cognitifs.

Quels risques liés à la leucémie?

Les patients peuvent développer des infections graves et des saignements excessifs.

Quelles complications de la thrombocytopénie?

Des saignements internes et externes peuvent survenir, mettant la vie en danger.

Quels risques de la polycythémie vera?

Elle peut entraîner des complications thromboemboliques, comme des AVC ou des crises cardiaques.

Quelles complications des infections sanguines?

Des complications graves incluent le choc septique et la défaillance multiviscérale.

Quels facteurs de risque pour l'anémie?

Une mauvaise alimentation, des maladies chroniques et des pertes sanguines fréquentes augmentent le risque.

Quels facteurs de risque pour la leucémie?

L'exposition à des radiations et certains produits chimiques peuvent augmenter le risque.

Quels facteurs de risque pour la thrombocytopénie?

Certaines maladies auto-immunes et infections virales peuvent contribuer à la thrombocytopénie.

Quels facteurs de risque pour la polycythémie?

Le tabagisme, l'apnée du sommeil et la vie en altitude sont des facteurs de risque connus.

Quels facteurs de risque pour les infections sanguines?

Les patients immunodéprimés et ceux avec des dispositifs intraveineux sont à risque accru.

Système hématopoïétique - Informations médicales vérifiées

Topical diquafosol versus hyaluronic acid for the treatment of dry eye disease: a meta-analysis of randomized controlled trials.

Dec 2023

DOI: 10.1007/s00417-023-06083-4 PMID: 37162564

Diquafosol enhances fluid transfer and mucin secretion on ocular surface, which has been suggested as an effective treatment for dry eye disease (DED). The aim of the systematic review and meta-analys... Relevant randomized controlled trials were obtained via search of electronic including PubMed, Embase, Cochrane Library, and Web of Science. A random-effects model was used to pool the results after i... A total of nine RCTs involving 1295 patients with DED were included in the meta-analysis. Compared to treatment with 0.1% HA, topical treatment with 3% diquafosol significantly improved the Ocular Sur... Topical treatment with 3% diquafosol may be more effective than 0.1% HA for patients with DED. However, the long-term efficacy and tolerability of diquafosol still need to be determined....

Humans Hyaluronic Acid Ophthalmic Solutions Randomized Controlled Trials as Topic Dry Eye Syndromes +1 autres

The UPDATE trial (UVB Phototherapy in Dermatology for ATopic Eczema): study protocol for a randomized controlled trial of narrowband UVB with optimal topical therapy versus optimal topical therapy in patients with atopic eczema.

16 Jul 2024

DOI: 10.1186/s13063-024-08334-z PMID: 39014498

Narrowband ultraviolet B (NB-UVB) phototherapy is commonly prescribed for patients with moderate-to-severe atopic eczema (AE). The efficacy of NB-UVB, however, has not yet properly been established, a... A pragmatic, multicenter, PROBE trial will be performed with 1:1 randomization of 316 adult patients with moderate-to-severe AE who have inadequate disease control with topical therapy and who are eli... The UPDATE trial aims to provide high-quality evidence regarding the (cost-)effectiveness and safety of NB-UVB phototherapy in moderate-to-severe AE patients. Challenges that are addressed in the prot... ClinicalTrials.gov NCT05704205. Registered on December 8, 2022....

Humans Ultraviolet Therapy Dermatitis, Atopic Prospective Studies Multicenter Studies as Topic +11 autres

Design and Methodological Issues of Within-Person (Split-Body) Randomized Controlled Trials Evaluating a Topical Treatment: A Systematic Review.

2023

DOI: 10.1159/000530149 PMID: 36990057

Topical drugs are often used as first-line treatment for dermatological conditions. A within-person design may then be well adapted: it consists of randomizing lesions/body sites rather than patients,... The aim of this review was to provide a methodological overview of within-person randomized trials (WP-RCTs) in dermatology.... We searched for eligible trials published between 2017 and 2021 in MEDLINE, Embase, and Central in dermatology journals and the 6 highest-impact-factor general medical journals. Two authors selected p... From 1,034 articles identified, we included 54 WP-RCTs, mainly for acne vulgaris, psoriasis, actinic keratosis, and atopic dermatitis. In most of the trials, patients had only 2 lesions/body sites. In... Our systematic review highlights that despite the publication of the CONSORT checklist extension for WP-RCTs in 2017, this design is rarely used, and when it is, there are methodological and reporting...

Humans Randomized Controlled Trials as Topic Acne Vulgaris Dermatitis, Atopic Checklist

Laser and light therapy combined with topical minoxidil for alopecia areata: a systematic review and meta-analysis of randomized controlled trials.

17 Feb 2023

DOI: 10.1007/s10103-023-03734-0 PMID: 36800063

We aim to evaluate the clinical efficacy and safety of using laser and light combined with topical minoxidil for alopecia areata. We searched PubMed, Embase, Web of Science, the Cochrane Library, Chin...

Humans Minoxidil Alopecia Areata Randomized Controlled Trials as Topic Phototherapy +1 autres

Nd:YAG/Er:YAG dual laser vs. topical steroid to treat vulvar lichen sclerosus: study protocol of a randomized controlled trial.

08 2023

DOI: 10.1007/s00404-023-07055-z PMID: 37145134

Vulvar lichen sclerosus (LS) is a chronic debilitating inflammatory skin disease. Today, the gold standard is a life-long topical steroid treatment. Alternative options are highly desired. We present ... We recruited 66 patients, 44 in the laser arm and 22 in the steroid arm. Patients with a physician-administered clinical LS score ≥ 4 were included. Participants received either four laser treatments ... The findings of this trial have the potential to offer a novel treatment option for LS. The standardized Nd:YAG/Er:YAG laser settings and the treatment regime are presented in this paper.... NCT03926299....

Female Humans Vulvar Lichen Sclerosus Lasers, Solid-State Prospective Studies +4 autres

Efficacy and safety of compound glycyrrhizin combined with topical minoxidil for alopecia areata: a systematic review and meta-analysis of randomized controlled trials.

Dec 2024

DOI: 10.1080/09546634.2024.2381766 PMID: 39230160

Alopecia areata (AA) is a common autoimmune skin disease. Our study aimed to systematically evaluate the efficacy and safety of compound glycyrrhizin (CG) combined with topical minoxidil therapy in tr... We searched the PubMed, EMBASE, Cochrane Library, Web of Science, CNKI, Wanfang, and VIP databases. Randomized controlled trials (RCTs) on CG combined with topical minoxidil therapy compared with topi... 11 RCTs and 1189 patients were included. Compared with topical minoxidil therapy alone, CG combined with topical minoxidil therapy was more effective at improving the clinical efficacy (RR = 1.36, 95%... The current evidence indicates that CG combined with topical minoxidil therapy is effective and safe for AA. However, owing to the suboptimal quality of the included studies, more high-quality and lar...

Humans Alopecia Areata Minoxidil Randomized Controlled Trials as Topic Drug Therapy, Combination +3 autres

Efficacy and Safety of Topical Application of Olive Oil for Preventing Pressure Ulcers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

13 11 2022

DOI: 10.3390/ijerph192214921 PMID: 36429639

The purpose was to identify and summarize the existing evidence on the efficacy and safety of the topical application of olive oil for preventing pressure ulcers (PUs). We included only randomized con...

Humans Pressure Ulcer Olive Oil Randomized Controlled Trials as Topic Incidence +1 autres

Clinical efficacy and safety of topical difamilast in the treatment of patients with atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials.

Dec 2022

DOI: 10.1080/17512433.2022.2134114 PMID: 36210241

To investigate the clinical efficacy and safety of topical difamilast in mild-to-moderate atopic dermatitis (AD).... Only randomized controlled trials (RCTs) that compared topical difamilast with vehicle treatment for patients with AD were included. PubMed, Web of Science, Ovid Medline, Cochrane Library, ClinicalTri... Five studies enrolling a total of 1009 patients with mild-to-moderate AD were identified. Compared with the topical vehicle, topical difamilast was associated with a significantly higher success rate ... This meta-analysis suggests that topical difamilast is an effective and safe treatment for mild-to-moderate AD....

Humans Dermatitis, Atopic Randomized Controlled Trials as Topic Treatment Outcome Eczema +2 autres

Effectiveness of laser and topical tranexamic acid combination therapy in melasma: An updated systematic review and meta-analysis of randomized controlled trials.

16 Jun 2023

DOI: 10.1007/s10103-023-03810-5 PMID: 37326860

Melasma is a chronic relapsing skin condition. Laser therapy is a new advancement in treatment. Whether the topical application of tranexamic acid (TXA) increases the efficacy of laser therapy in mela...

Humans Tranexamic Acid Carbon Dioxide Randomized Controlled Trials as Topic Lasers, Gas +2 autres

Randomized controlled trials of biomarker targets.

02 2023

DOI: 10.1177/17407745221131820 PMID: 36373783

Randomized controlled trials are used to estimate the causal effect of a treatment on a health outcome of interest in a patient population. Often the specified treatment in a randomized controlled tri... We use causal reasoning to explain why randomized controlled trials of biomarker targets can arrive at conflicting or misleading conclusions. We describe four key threats to the validity of trials of ... We illustrate these findings using evidence from 15 randomized controlled trials of blood pressure targets for management of hypertension. Randomized trials of blood pressure targets exhibit substanti... Researchers should critically assess meta-analyses of trials of targets for variation in the types, distributions, and off-target effects of therapies studied. Trial investigators should release detai...

Humans Randomized Controlled Trials as Topic Hypertension Blood Pressure Biomarkers

Système hématopoïétique : Questions médicales fréquentes

Termes MeSH sélectionnés :

Questions fréquentes et termes MeSH associés

Diagnostic 5

Symptômes 5

Prévention 5

Traitements 5

Complications 5

Facteurs de risque 5

Contenu validé par Dr Olivier Menir

Sous-catégories

Cellules de la moelle osseuse

Cellules souches hématopoïétiques

Mégacaryocytes

Réticulocytes

Progéniteurs lymphoïdes

Progéniteurs myéloïdes

Progéniteurs des granulocytes et macrophages

Progéniteurs érythroïdes et mégacaryocytaires

Précurseurs des granulocytes

Précurseurs des monocytes et macrophages

Précurseurs érythroïdes

Progéniteurs mégacaryocytaires

Érythroblastes

Mégaloblastes

Auteurs principaux

Sources (10000 au total)