questionsmedicales.fr
Maladies endocriniennes
Maladies de l'hypophyse
Hyperpituitarisme
Hyperprolactinémie
Hyperprolactinémie : Questions médicales fréquentes
Diagnostic
5
Hyperprolactinémie
Prolactine
Prolactine
Hyperprolactinémie
Galactorrhée
Dysfonction érectile
Hyperprolactinémie
Asymptomatique
Symptômes
5
Maux de tête
Tumeur hypophysaire
Libido
Dysfonction sexuelle
Prévention
5
Mode de vie
Alimentation équilibrée
Antipsychotiques
Médicaments
Gestion du stress
Méditation
Examens réguliers
Anomalies hormonales
Traitements
5
Cabergoline
Agonistes de la dopamine
Chirurgie
Tumeur hypophysaire
Effets secondaires
Nausées
Surveillance médicale
Traitement
Complications
5
Santé osseuse
Densité osseuse
Cancer
Hyperprolactinémie
Grossesse
Fausses couches
Troubles visuels
Nerf optique
Facteurs de risque
5
Antécédents familiaux
Tumeurs hypophysaires
Femmes
Hyperprolactinémie
Maladies endocriniennes
Hypothyroïdie
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{
"@type": "Question",
"name": "Quels examens complémentaires sont nécessaires ?",
"position": 2,
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}
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{
"@type": "Question",
"name": "Quels niveaux de prolactine indiquent une hyperprolactinémie ?",
"position": 3,
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"text": "Des niveaux supérieurs à 25 ng/mL chez les femmes et 15 ng/mL chez les hommes sont préoccupants."
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"@type": "Question",
"name": "Quels symptômes peuvent indiquer un diagnostic ?",
"position": 4,
"acceptedAnswer": {
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"text": "Des irrégularités menstruelles, galactorrhée ou dysfonction érectile peuvent alerter."
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"@type": "Question",
"name": "Peut-on avoir une hyperprolactinémie sans symptômes ?",
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"@type": "Question",
"name": "Quels sont les symptômes courants de l'hyperprolactinémie ?",
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"@type": "Question",
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"@type": "Question",
"name": "Les femmes enceintes peuvent-elles avoir une hyperprolactinémie ?",
"position": 9,
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{
"@type": "Question",
"name": "Quels signes indiquent une galactorrhée ?",
"position": 10,
"acceptedAnswer": {
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"text": "La galactorrhée se manifeste par l'écoulement de lait des seins en dehors de l'allaitement."
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{
"@type": "Question",
"name": "Peut-on prévenir l'hyperprolactinémie ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de méthode spécifique de prévention, mais un suivi médical régulier aide."
}
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{
"@type": "Question",
"name": "Quels modes de vie peuvent réduire les risques ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain, incluant une alimentation équilibrée et l'exercice, peut aider."
}
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{
"@type": "Question",
"name": "Les médicaments peuvent-ils causer l'hyperprolactinémie ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains médicaments comme les antipsychotiques peuvent augmenter les niveaux de prolactine."
}
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{
"@type": "Question",
"name": "Comment gérer le stress pour prévenir l'hyperprolactinémie ?",
"position": 14,
"acceptedAnswer": {
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}
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{
"@type": "Question",
"name": "Les examens réguliers sont-ils importants ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des examens réguliers permettent de détecter précocement des anomalies hormonales."
}
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{
"@type": "Question",
"name": "Quels traitements sont disponibles pour l'hyperprolactinémie ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les agonistes de la dopamine comme la cabergoline sont souvent prescrits."
}
},
{
"@type": "Question",
"name": "Quand faut-il envisager une chirurgie ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "La chirurgie est envisagée si une tumeur hypophysaire provoque des symptômes sévères."
}
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{
"@type": "Question",
"name": "Les traitements sont-ils efficaces ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la plupart des patients répondent bien aux traitements médicamenteux."
}
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{
"@type": "Question",
"name": "Y a-t-il des effets secondaires aux traitements ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des effets secondaires comme des nausées ou des vertiges peuvent survenir."
}
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{
"@type": "Question",
"name": "Peut-on arrêter le traitement après amélioration ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est conseillé de continuer le traitement sous surveillance médicale même après amélioration."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec l'hyperprolactinémie ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent l'infertilité, l'ostéoporose et des troubles visuels."
}
},
{
"@type": "Question",
"name": "L'hyperprolactinémie peut-elle affecter la santé osseuse ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des niveaux élevés de prolactine peuvent entraîner une diminution de la densité osseuse."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque accru de cancer ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, il n'y a pas de lien direct prouvé entre hyperprolactinémie et cancer."
}
},
{
"@type": "Question",
"name": "Comment l'hyperprolactinémie affecte-t-elle la grossesse ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut entraîner des complications comme des fausses couches ou des accouchements prématurés."
}
},
{
"@type": "Question",
"name": "Les troubles visuels sont-ils fréquents ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des troubles visuels peuvent survenir si une tumeur hypophysaire exerce une pression sur le nerf optique."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque de l'hyperprolactinémie ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux, des tumeurs hypophysaires et certains médicaments."
}
},
{
"@type": "Question",
"name": "Le stress peut-il être un facteur de risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut contribuer à l'augmentation des niveaux de prolactine."
}
},
{
"@type": "Question",
"name": "Les femmes sont-elles plus à risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les femmes sont plus souvent touchées par l'hyperprolactinémie que les hommes."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque d'hyperprolactinémie ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le risque augmente généralement avec l'âge, surtout chez les femmes en périménopause."
}
},
{
"@type": "Question",
"name": "Les maladies endocriniennes sont-elles un facteur de risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des maladies comme l'hypothyroïdie peuvent augmenter le risque d'hyperprolactinémie."
}
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}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 21/07/2026
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Institute of Endocrinology, Beilinson Hospital, Petach Tikva, Israel. ilanshi@clalit.org.il.
Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel. ilanshi@clalit.org.il.
Publications dans "Hyperprolactinémie" :
3 publications dans cette catégorie
Affiliations :
Department of Internal Medicine and Clinical Pharmacology, Medical University of Silesia, Katowice, Poland.
Publications dans "Hyperprolactinémie" :
3 publications dans cette catégorie
Affiliations :
Department of Internal Medicine and Clinical Pharmacology, Medical University of Silesia, Katowice, Poland.
Publications dans "Hyperprolactinémie" :
2 publications dans cette catégorie
Affiliations :
Division of Endocrinology, Hospital das Clinicas, Federal University of Pernambuco, Recife, Brazil, lvilarf@gmail.com.
Pernambuco Endocrine Research Center, Recife, Brazil, lvilarf@gmail.com.
Publications dans "Hyperprolactinémie" :
2 publications dans cette catégorie
Affiliations :
Pernambuco Endocrine Research Center, Recife, Brazil.
Publications dans "Hyperprolactinémie" :
2 publications dans cette catégorie
Affiliations :
Division of Endocrinology, Hospital das Clinicas, Federal University of Pernambuco, Recife, Brazil.
Publications dans "Hyperprolactinémie" :
2 publications dans cette catégorie
Affiliations :
Psychiatric Hospital "Sveti Ivan", Jankomir 11, 10090 Zagreb, Croatia, sandra.pisk@pbsvi.hr.
Publications dans "Hyperprolactinémie" :
2 publications dans cette catégorie
Affiliations :
Institute of Endocrinology, Beilinson Hospital, Petach Tikva, Israel.
Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Publications dans "Hyperprolactinémie" :
2 publications dans cette catégorie
Affiliations :
Maccabi Health Care Services, Tel Aviv, Israel.
Publications dans "Hyperprolactinémie" :
2 publications dans cette catégorie
Affiliations :
Institute of Endocrinology, Beilinson Hospital, Petach Tikva, Israel.
Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Publications dans "Hyperprolactinémie" :
2 publications dans cette catégorie
Affiliations :
Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. amit.akirov@gmail.com.
Institute of Endocrinology, Rabin Medical Center, Beilinson Hospital, Petach Tikva, 49100, Israel. amit.akirov@gmail.com.
Publications dans "Hyperprolactinémie" :
2 publications dans cette catégorie
Affiliations :
Department of Animal Science, University of California, Davis, Davis, CA 95616, USA.
Publications dans "Hyperprolactinémie" :
2 publications dans cette catégorie
Affiliations :
Agriculture and Agri-Food Canada, Sherbrooke R&D Centre, Sherbrooke, QC J1M 0C8, Canada. Electronic address: chantal.farmer@canada.ca.
Publications dans "Hyperprolactinémie" :
2 publications dans cette catégorie
Affiliations :
Department of Internal Medicine and Clinical Pharmacology, Medical University of Silesia, Katowice, Poland.
Publications dans "Hyperprolactinémie" :
1 publication dans cette catégorie
Affiliations :
Division of Endocrinology, IRCCS San Raffaele Hospital, San Raffaele Vita-Salute University, Via Olgettina, 58, Milan, 20132, Italy.
Publications dans "Hyperprolactinémie" :
1 publication dans cette catégorie
Affiliations :
Division of Endocrinology, IRCCS San Raffaele Hospital, San Raffaele Vita-Salute University, Via Olgettina, 58, Milan, 20132, Italy.
Publications dans "Hyperprolactinémie" :
1 publication dans cette catégorie
Affiliations :
Endocrinology/Medicine Departments, Hospital Sant Pau, Barcelona, Spain.
Publications dans "Hyperprolactinémie" :
1 publication dans cette catégorie
Affiliations :
Division of Endocrinology, IRCCS San Raffaele Hospital, San Raffaele Vita-Salute University, Via Olgettina, 58, Milan, 20132, Italy. giustina.andrea@hsr.it.
Publications dans "Hyperprolactinémie" :
1 publication dans cette catégorie
Publications dans "Hyperprolactinémie" :
1 publication dans cette catégorie
Publications dans "Hyperprolactinémie" :
Hyperprolactinemia accompanies growth hormone hypersecretion in approximately 25-39% of cases. There is a recommendation to determine the level of prolactin in clinical guidelines for diagnosis and tr...
Determining the proportion of patients with hyperprolactinemia and pituitary adenoma, who were examined for IGF-1 levels, and identifying the proportion of patients with acromegaly among this cohort....
Between December 2019 and December 2022 a single-center observational single-stage single-sample uncontrolled study was conducted. At the first stage of the study, the proportion of patients with pitu...
At the first stage, 105 patients were included in the study. The level of IGF-1 was determined in 41/105 (39%) cases. There were 22/41 (53.7%) cases in the subgroup with pituitary incidentalomas and 1...
In real clinical practice the level of IGF-1 is studied only in 39% of cases in patients with pituitary adenoma and hyperprolactinemia. The disease was detected in 3 cases (3.2%) out of 94 people with...
Ovulatory dysfunction is usually caused by an endocrine disorder, of which polycystic ovary syndrome (PCOS) is the most common cause. PCOS is usually associated with estrogen levels within the normal ...
This retrospective cross-sectional study contains data of 1429 women with PCOS and 299 women without PCOS. Main outcome measures included thyroid stimulating hormone (TSH), Free Thyroxine (FT4), and a...
The prevalence of thyroid disease in PCOS women was similar to that of controls (1.9% versus 2.7%; P = 0.39 for hypothyroidism and 0.5% versus 0%; P = 0.99 for hyperthyroidism). TSH levels were also s...
Women with PCOS do not suffer from thyroid dysfunction more often than controls. Also, the prevalence of positive TPOab, being a marker for future risk of thyroid pathology, was similar in both groups...
Tetrahydrobiopterin (BH...
In this study, we reviewed the clinical courses of 12 adolescent and adult patients (7 females and 5 males) with PTPS deficiency....
The patients were treated shortly after diagnosis through newborn screening with a combination of BH...
Hyperprolactinemia is common in female patients with PTPS deficiency, especially after puberty. A long-acting dopamine agonist, such as cabergoline, may be a necessary adjunctive treatment for most pa...
Determining the etiology of hyperprolactinemia is fundamental for selecting the most appropriate treatment strategy. The aim of this study was to evaluate the usefulness and accuracy of prolactin leve...
In this retrospective study, we reviewed medical records of patients with nonphysiological hyperprolactinemia seen at two neuroendocrine reference centers located in Recife, Brazil, from January 2000 ...
The study included 770 patients aged 12-73 years (65% female). The three most frequent etiologies of hyperprolactinemia were prolactinomas (n = 263; 34.2%), drug-induced hyperprolactinemia (n = 160; 2...
Despite considerable overlap in prolactin levels among the different etiologies of hyperprolactinemia, values > 250 ng/mL allowed a clear distinction between macroprolactinomas and nonfunctioning pitu...
Acromegaly due to ectopic secretion of growth hormone-releasing hormone (GHRH) is a rare disorder. The signs and symptoms of ectopic acromegaly are indistinguishable from acromegaly due to a somatotro...
Periodontal disease is a major health problem that results in tooth loss and thus affects oral health, which affects quality of life. In particular, schizophrenic patients are at higher risk for perio...
The study population consisted of three groups: Group A (n = 21): schizophrenic patients that have been taking "prolactin-inducing" antipsychotics for at least 1 year; Group B (n = 21): schizophrenic ...
Results revealed a statistically significant difference in PD, CAL, and serum prolactin levels (P ≤ 0.001, P = 0.001, and P ≤ 0.001, respectively) among the 3 study groups. For both PD and CAL measure...
According to our results, it could be concluded that all antipsychotics contribute to the progression of periodontal disease, with a higher risk for prolactin-inducing antipsychotics. However, further...
To describe a series of cases with pharmacological hyperprolactinemia in primary care setting and the prolactin levels, clinical implications of different causes of pharmacological hyperprolactinemia....
A retrospective study of all patients with detected hyperprolactinemia in hormonal studies was performed between 2019 and 2020 in 20 Spanish primary care centers. Hyperprolactinemia is defined as a se...
From a sample of 501 patients with elevated serum prolactin, 39.4% (n=162) had pharmacological hyperprolactinemia. The most common cause of pharmacological hyperprolactinemia in women was OCPs (n=61) ...
In this series of cases, drugs represented the 39.4% of the causes of hyperprolactinemia. The most common drugs were OCPs in women and antipsychotics/antidepressants in men. Antidepressants/antipsycho...
Hyperprolactinemia is an endocrinological disorder that might arise from various physiologic or pathologic conditions, as well as from pharmacologic sources. These pharmacologic sources include antide...
The commonest medications prescribed in functional dyspepsia are prokinetic agents, specifically domperidone. However, its administration at times elevates serum prolactin levels, which can lead to pa...
Prolactin (PRL) is a polypeptide hormone produced by the lactotrope cells of the anterior pituitary gland. Among its myriads of biological functions, PRL is the main regulator of mammary gland growth ...