questionsmedicales.fr
Systèmes sanguin et immunitaire
Système immunitaire
Phagocytes
Granulocytes neutrophiles
Granulocytes neutrophiles : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Phagocytose
Dégranulation
Infection bactérienne
Fièvre
Inflammation
Protéine C-réactive
Neutrophiles
Réponse immunitaire
Prévention
5
Prévention des infections
Vaccinations
Alimentation
Système immunitaire
Neutropénie
Médicaments immunosuppresseurs
Traitements
5
Neutropénie
Antibiotiques
Antibiotiques
Infections bactériennes
Corticostéroïdes
Inflammation
Infections virales
Antiviraux
Complications
5
Neutropénie
Infections graves
Infections récurrentes
Neutropénie
Infection
Dommages organiques
Effets secondaires
Infections
Facteurs de risque
5
Neutropénie
Traitements anticancéreux
Maladies héréditaires
Production de neutrophiles
Infections virales
Neutrophiles
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Granulocytes neutrophiles : Questions médicales les plus fréquentes",
"headline": "Granulocytes neutrophiles : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Granulocytes neutrophiles : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-08-03",
"dateModified": "2025-04-30",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Granulocytes neutrophiles"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Phagocytes",
"url": "https://questionsmedicales.fr/mesh/D010586",
"about": {
"@type": "MedicalCondition",
"name": "Phagocytes",
"code": {
"@type": "MedicalCode",
"code": "D010586",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "A15.382.680"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Granulocytes neutrophiles",
"alternateName": "Neutrophils",
"code": {
"@type": "MedicalCode",
"code": "D009504",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Andrés Hidalgo",
"url": "https://questionsmedicales.fr/author/Andr%C3%A9s%20Hidalgo",
"affiliation": {
"@type": "Organization",
"name": "Area of Cell and Developmental Biology, Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain."
}
},
{
"@type": "Person",
"name": "Mary C Dinauer",
"url": "https://questionsmedicales.fr/author/Mary%20C%20Dinauer",
"affiliation": {
"@type": "Organization",
"name": "Department of Pediatrics (Hematology/Oncology), St. Louis Children's Hospital, Washington University School of Medicine in St. Louis, St. Louis, MO, USA. mdinauer@wustl.edu."
}
},
{
"@type": "Person",
"name": "Lai Guan Ng",
"url": "https://questionsmedicales.fr/author/Lai%20Guan%20Ng",
"affiliation": {
"@type": "Organization",
"name": "Singapore Immunology Network (SIgN), A*STAR, Biopolis, Singapore, Singapore. Ng_Lai_Guan@immunol.a-star.edu.sg."
}
},
{
"@type": "Person",
"name": "William M Nauseef",
"url": "https://questionsmedicales.fr/author/William%20M%20Nauseef",
"affiliation": {
"@type": "Organization",
"name": "Inflammation Program, Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine University of Iowa, Iowa City, Iowa, USA."
}
},
{
"@type": "Person",
"name": "Chih-Chao Chiang",
"url": "https://questionsmedicales.fr/author/Chih-Chao%20Chiang",
"affiliation": {
"@type": "Organization",
"name": "Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Segregation of Ca2+ signaling in olfactory signal transduction.",
"datePublished": "2023-02-14",
"url": "https://questionsmedicales.fr/article/36787110",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1085/jgp.202213165"
}
},
{
"@type": "ScholarlyArticle",
"name": "Diacylglycerol Kinases in Signal Transduction.",
"datePublished": "2022-07-29",
"url": "https://questionsmedicales.fr/article/35955558",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3390/ijms23158423"
}
},
{
"@type": "ScholarlyArticle",
"name": "Overview of Cancer Metabolism and Signaling Transduction.",
"datePublished": "2022-12-20",
"url": "https://questionsmedicales.fr/article/36613455",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3390/ijms24010012"
}
},
{
"@type": "ScholarlyArticle",
"name": "Signal Transduction and Gene Regulation in the Endothelium.",
"datePublished": "2023-01-03",
"url": "https://questionsmedicales.fr/article/35667710",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1101/cshperspect.a041153"
}
},
{
"@type": "ScholarlyArticle",
"name": "Signal Transduction Regulators in Axonal Regeneration.",
"datePublished": "2022-05-04",
"url": "https://questionsmedicales.fr/article/35563843",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3390/cells11091537"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Systèmes sanguin et immunitaire",
"item": "https://questionsmedicales.fr/mesh/D006424"
},
{
"@type": "ListItem",
"position": 3,
"name": "Système immunitaire",
"item": "https://questionsmedicales.fr/mesh/D007107"
},
{
"@type": "ListItem",
"position": 4,
"name": "Phagocytes",
"item": "https://questionsmedicales.fr/mesh/D010586"
},
{
"@type": "ListItem",
"position": 5,
"name": "Granulocytes neutrophiles",
"item": "https://questionsmedicales.fr/mesh/D009504"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Granulocytes neutrophiles - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Granulocytes neutrophiles",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-02",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Granulocytes neutrophiles",
"description": "Comment diagnostiquer une neutropénie ?\nQuels tests pour évaluer la fonction des neutrophiles ?\nQuels signes indiquent une infection bactérienne ?\nComment évaluer une inflammation ?\nQuel rôle des neutrophiles dans le diagnostic ?",
"url": "https://questionsmedicales.fr/mesh/D009504?mesh_terms=Signal+Transduction#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Granulocytes neutrophiles",
"description": "Quels symptômes d'une infection aiguë ?\nComment reconnaître une neutropénie ?\nQuels signes d'inflammation ?\nQuels symptômes d'une septicémie ?\nQuels symptômes d'une infection virale ?",
"url": "https://questionsmedicales.fr/mesh/D009504?mesh_terms=Signal+Transduction#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Granulocytes neutrophiles",
"description": "Comment prévenir les infections ?\nQuel rôle de l'alimentation ?\nComment éviter la neutropénie ?\nQuels conseils pour les patients neutropéniques ?\nComment gérer le stress pour la santé ?",
"url": "https://questionsmedicales.fr/mesh/D009504?mesh_terms=Signal+Transduction#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Granulocytes neutrophiles",
"description": "Comment traiter une neutropénie ?\nQuels antibiotiques pour infections bactériennes ?\nQuel rôle des corticostéroïdes ?\nComment gérer une septicémie ?\nQuels traitements pour infections virales ?",
"url": "https://questionsmedicales.fr/mesh/D009504?mesh_terms=Signal+Transduction#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Granulocytes neutrophiles",
"description": "Quelles complications d'une neutropénie ?\nQuels risques d'infections récurrentes ?\nComment la septicémie évolue-t-elle ?\nQuelles conséquences d'une infection non traitée ?\nQuels effets secondaires des traitements ?",
"url": "https://questionsmedicales.fr/mesh/D009504?mesh_terms=Signal+Transduction#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Granulocytes neutrophiles",
"description": "Quels facteurs augmentent le risque de neutropénie ?\nQuel impact de l'âge sur les neutrophiles ?\nComment les maladies héréditaires influencent-elles ?\nQuel rôle des infections virales ?\nQuels comportements à risque ?",
"url": "https://questionsmedicales.fr/mesh/D009504?mesh_terms=Signal+Transduction#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer une neutropénie ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un hémogramme permet de mesurer le nombre de neutrophiles dans le sang."
}
},
{
"@type": "Question",
"name": "Quels tests pour évaluer la fonction des neutrophiles ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests de phagocytose et de dégranulation peuvent être réalisés."
}
},
{
"@type": "Question",
"name": "Quels signes indiquent une infection bactérienne ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fièvre, frissons, et augmentation des neutrophiles dans le sang sont des indicateurs."
}
},
{
"@type": "Question",
"name": "Comment évaluer une inflammation ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des marqueurs comme la protéine C-réactive et la vitesse de sédimentation sont utilisés."
}
},
{
"@type": "Question",
"name": "Quel rôle des neutrophiles dans le diagnostic ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils sont souvent mesurés pour évaluer la réponse immunitaire et détecter des infections."
}
},
{
"@type": "Question",
"name": "Quels symptômes d'une infection aiguë ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fièvre, douleur, rougeur et gonflement au site d'infection sont fréquents."
}
},
{
"@type": "Question",
"name": "Comment reconnaître une neutropénie ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les infections fréquentes et des symptômes comme la fatigue peuvent indiquer une neutropénie."
}
},
{
"@type": "Question",
"name": "Quels signes d'inflammation ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Rougeur, chaleur, douleur et gonflement sont des signes typiques d'inflammation."
}
},
{
"@type": "Question",
"name": "Quels symptômes d'une septicémie ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fièvre élevée, confusion, et hypotension peuvent indiquer une septicémie."
}
},
{
"@type": "Question",
"name": "Quels symptômes d'une infection virale ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Symptômes comme la toux, la fatigue et les douleurs musculaires peuvent survenir."
}
},
{
"@type": "Question",
"name": "Comment prévenir les infections ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une bonne hygiène, des vaccinations et éviter les contacts avec des malades sont essentiels."
}
},
{
"@type": "Question",
"name": "Quel rôle de l'alimentation ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée renforce le système immunitaire et aide à prévenir les infections."
}
},
{
"@type": "Question",
"name": "Comment éviter la neutropénie ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les médicaments immunosuppresseurs et surveiller les maladies héréditaires."
}
},
{
"@type": "Question",
"name": "Quels conseils pour les patients neutropéniques ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les foules, se laver les mains fréquemment et cuire les aliments correctement."
}
},
{
"@type": "Question",
"name": "Comment gérer le stress pour la santé ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des techniques de relaxation et d'exercice régulier peuvent aider à réduire le stress."
}
},
{
"@type": "Question",
"name": "Comment traiter une neutropénie ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement peut inclure des facteurs de croissance hématopoïétiques et des antibiotiques."
}
},
{
"@type": "Question",
"name": "Quels antibiotiques pour infections bactériennes ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antibiotiques comme la pénicilline ou les céphalosporines sont souvent prescrits."
}
},
{
"@type": "Question",
"name": "Quel rôle des corticostéroïdes ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent réduire l'inflammation et aider à traiter certaines maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Comment gérer une septicémie ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un traitement urgent avec des antibiotiques et des fluides intraveineux est crucial."
}
},
{
"@type": "Question",
"name": "Quels traitements pour infections virales ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antiviraux et les soins de soutien sont utilisés pour traiter les infections virales."
}
},
{
"@type": "Question",
"name": "Quelles complications d'une neutropénie ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les infections graves et les septicémies sont des complications fréquentes de la neutropénie."
}
},
{
"@type": "Question",
"name": "Quels risques d'infections récurrentes ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les patients neutropéniques sont plus susceptibles de développer des infections récurrentes."
}
},
{
"@type": "Question",
"name": "Comment la septicémie évolue-t-elle ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Sans traitement, la septicémie peut entraîner un choc septique et la mort."
}
},
{
"@type": "Question",
"name": "Quelles conséquences d'une infection non traitée ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une infection non traitée peut se propager et causer des dommages organiques graves."
}
},
{
"@type": "Question",
"name": "Quels effets secondaires des traitements ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements peuvent entraîner des effets secondaires comme des nausées et des infections."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque de neutropénie ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements anticancéreux, certaines infections et maladies auto-immunes augmentent le risque."
}
},
{
"@type": "Question",
"name": "Quel impact de l'âge sur les neutrophiles ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les personnes âgées peuvent avoir une diminution naturelle du nombre de neutrophiles."
}
},
{
"@type": "Question",
"name": "Comment les maladies héréditaires influencent-elles ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies génétiques peuvent affecter la production de neutrophiles."
}
},
{
"@type": "Question",
"name": "Quel rôle des infections virales ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les infections virales peuvent temporairement réduire le nombre de neutrophiles."
}
},
{
"@type": "Question",
"name": "Quels comportements à risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le tabagisme et une mauvaise hygiène de vie augmentent le risque d'infections."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 30/04/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Area of Cell and Developmental Biology, Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain.
Institute for Cardiovascular Prevention, Ludwig Maximillians University, Munich, Germany.
Publications dans "Granulocytes neutrophiles" :
2 publications dans cette catégorie
Affiliations :
Department of Pediatrics (Hematology/Oncology), St. Louis Children's Hospital, Washington University School of Medicine in St. Louis, St. Louis, MO, USA. mdinauer@wustl.edu.
Department of Pathology and Immunology, St. Louis Children's Hospital, Washington University School of Medicine in St. Louis , St. Louis, MO, USA. mdinauer@wustl.edu.
Publications dans "Granulocytes neutrophiles" :
2 publications dans cette catégorie
Affiliations :
Singapore Immunology Network (SIgN), A*STAR, Biopolis, Singapore, Singapore. Ng_Lai_Guan@immunol.a-star.edu.sg.
Publications dans "Granulocytes neutrophiles" :
2 publications dans cette catégorie
Affiliations :
Inflammation Program, Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine University of Iowa, Iowa City, Iowa, USA.
Publications dans "Granulocytes neutrophiles" :
2 publications dans cette catégorie
Affiliations :
Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Supervisor Board, Taoyuan Chinese Medicine Association, Taoyuan, Taiwan.
Puxin Fengze Chinese Medicine Clinic, Taoyuan, Taiwan.
Publications dans "Granulocytes neutrophiles" :
2 publications dans cette catégorie
Affiliations :
Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
School of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan.
Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Publications dans "Granulocytes neutrophiles" :
2 publications dans cette catégorie
Affiliations :
Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Research Center for Chinese Herbal Medicine, Research Center for Food and Cosmetic Safety, and Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology, Taoyuan, Taiwan.
Department of Biotechnology, College of Life Science, Kaohsiung Medical University, Kaohsiung, Taiwan.
Publications dans "Granulocytes neutrophiles" :
2 publications dans cette catégorie
Affiliations :
School of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan.
Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Research Center for Chinese Herbal Medicine, Research Center for Food and Cosmetic Safety, and Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology, Taoyuan, Taiwan.
Chinese Herbal Medicine Research Team, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.
Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Department of Chemical Engineering, Ming Chi University of Technology, New Taipei City, Taiwan.
Publications dans "Granulocytes neutrophiles" :
2 publications dans cette catégorie
Affiliations :
Division of Nephrology, Department of Medicine IV University Hospital LMU, 80336 Munich, Germany.
Publications dans "Granulocytes neutrophiles" :
2 publications dans cette catégorie
Affiliations :
Division of Pharmacology, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Publications dans "Granulocytes neutrophiles" :
2 publications dans cette catégorie
Publications dans "Granulocytes neutrophiles" :
2 publications dans cette catégorie
Affiliations :
Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Shanghai Key laboratory of Perioperative Stress and Protection, Shanghai, China.
Department of Anesthesiology, Shanghai Medical College, Fudan University, Shanghai, China.
Publications dans "Granulocytes neutrophiles" :
2 publications dans cette catégorie
Affiliations :
Lomonosov Moscow State University, A. N. Belozersky Institute of Physico-Chemical Biology, 119991 Moscow, Russia.
Publications dans "Granulocytes neutrophiles" :
2 publications dans cette catégorie
Affiliations :
Area of Cell & Developmental Biology, Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain. Electronic address: ivan.ballesteros@cnic.es.
Publications dans "Granulocytes neutrophiles" :
2 publications dans cette catégorie
Affiliations :
CDL Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Publications dans "Granulocytes neutrophiles" :
1 publication dans cette catégorie
Affiliations :
Institutes of Integrative Medicine, Heilongjiang Provincial Hospital of Traditional Chinese Medicine, Heilongjiang, China.
Publications dans "Granulocytes neutrophiles" :
1 publication dans cette catégorie
Publications dans "Granulocytes neutrophiles" :
1 publication dans cette catégorie
Publications dans "Granulocytes neutrophiles" :
1 publication dans cette catégorie
Affiliations :
Department of Cellular Microbiology, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany.
Publications dans "Granulocytes neutrophiles" :
1 publication dans cette catégorie
Affiliations :
Department of Cellular Microbiology, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany.
Publications dans "Granulocytes neutrophiles" :
Olfactory signal transduction is conducted through a cAMP-mediated second messenger cascade. The cytoplasmic Ca2+ concentration increases through the opening of CNG channels, a phenomenon that underli...
In recent years, the significant research efforts put into the clarification of the PI3K/AKT/mTOR pathway resulted in the approval of the first targeted therapies based on lipid kinase inhibitors [......
Despite the remarkable progress in cancer treatment up to now, we are still far from conquering the disease. The most substantial change after the malignant transformation of normal cells into cancer ...
Extracellular signals act on G-protein-coupled receptors (GPCRs) to regulate homeostasis and adapt to stress. This involves rapid intracellular post-translational responses and long-lasting gene-expre...
Intracellular signal transduction in response to growth factor receptor activation is a fundamental process during the regeneration of the nervous system. In this context, intracellular inhibitors of ...
Unlike most higher plants, unicellular algae can acclimate to changes in irradiance on time scales of hours to a few days. The process involves an enigmatic signaling pathway originating in the plasti...
The involvement of the microRNA miR165a in the light-dependent mechanisms of regulation of target genes in maize (...
Signal transduction enables cells to sense and respond to chemical and mechanical information in the extracellular environment. Recently, phase separation has emerged as a physical mechanism that can ...
Microbes utilize numerous metal cofactor-containing proteins to recognize and respond to constantly fluctuating redox stresses in their environment. Gaining an understanding of how these metalloprotei...
G protein-coupled receptors (GPCRs) are coupled by four major subfamilies of G proteins. GPCR coupling is processed through a combination of common and selective activation mechanisms together. Common...