Radiographic Contrast Media and the Kidney.
AKI is a potential complication of intravascular iodinated contrast exposure. Contrast-associated AKI, which typically manifests as small and transient decrements in kidney function that develop withi...
Purines : Questions médicales fréquentes
Questions fréquentes et termes MeSH associés
Diagnostic 5
#1
Comment diagnostiquer une hyperuricémie ?
Un test sanguin mesure le taux d'acide urique pour diagnostiquer l'hyperuricémie.
#2
Quels tests pour la goutte ?
L'analyse du liquide synovial et des tests sanguins pour l'acide urique sont utilisés.
#3
Quels symptômes indiquent une crise de goutte ?
Douleur intense, rougeur et gonflement d'une articulation, souvent le gros orteil.
#4
Comment évaluer une maladie liée aux purines ?
Des tests génétiques et des analyses biochimiques peuvent être nécessaires.
#5
Quel rôle des purines dans le diagnostic ?
Les niveaux de purines peuvent indiquer des troubles métaboliques ou des maladies rénales.
Symptômes 5
#1
Quels sont les symptômes de l'hyperuricémie ?
Souvent asymptomatique, mais peut causer des douleurs articulaires et des calculs rénaux.
#2
Quels signes de goutte aiguë ?
Douleur intense, rougeur, chaleur et gonflement d'une articulation, souvent nocturne.
#3
Comment se manifeste une crise de goutte ?
Une douleur soudaine et sévère dans une articulation, souvent accompagnée d'inflammation.
#4
Quels symptômes des troubles des purines ?
Fatigue, douleurs articulaires, et parfois des problèmes rénaux ou hépatiques.
#5
Quels symptômes d'une maladie de Wilson ?
Accumulation de cuivre, troubles neurologiques, et symptômes hépatiques.
Prévention 5
#1
Comment prévenir l'hyperuricémie ?
Adopter un régime pauvre en purines et éviter l'alcool et les boissons sucrées.
#2
Quelles habitudes pour éviter la goutte ?
Maintenir un poids santé, rester hydraté et limiter les aliments riches en purines.
#3
Comment réduire le risque de calculs rénaux ?
Boire beaucoup d'eau et éviter les aliments riches en oxalates et purines.
#4
Quels conseils diététiques pour les purines ?
Limiter les viandes rouges, les fruits de mer et les boissons alcoolisées.
#5
Comment surveiller les niveaux d'acide urique ?
Des tests sanguins réguliers pour surveiller les niveaux d'acide urique et ajuster le régime.
Traitements 5
#1
Comment traiter l'hyperuricémie ?
Des médicaments comme les inhibiteurs de la xanthine oxydase et des changements alimentaires.
#2
Quel traitement pour la goutte ?
Anti-inflammatoires non stéroïdiens (AINS) et colchicine pour soulager la douleur.
#3
Comment prévenir les crises de goutte ?
Éviter les aliments riches en purines et maintenir une hydratation adéquate.
#4
Quels médicaments pour les troubles des purines ?
Des médicaments spécifiques selon le trouble, comme les uricosuriques pour l'hyperuricémie.
#5
Comment gérer les calculs rénaux liés aux purines ?
Hydratation, modifications alimentaires et parfois intervention chirurgicale.
Complications 5
#1
Quelles complications de la goutte ?
Arthrite chronique, dépôts de tophus et risque accru de maladies cardiovasculaires.
#2
Quels risques liés à l'hyperuricémie ?
Peut entraîner des calculs rénaux, des maladies rénales et des problèmes cardiovasculaires.
#3
Comment l'hyperuricémie affecte-t-elle les reins ?
Peut provoquer une néphropathie urique, entraînant des lésions rénales.
#4
Quelles complications des troubles des purines ?
Peuvent inclure des problèmes hépatiques, neurologiques et des troubles métaboliques.
#5
Quels effets à long terme de la goutte ?
Peut entraîner des dommages articulaires permanents et des complications systémiques.
Facteurs de risque 5
#1
Quels facteurs de risque pour l'hyperuricémie ?
Obésité, consommation excessive d'alcool, régime riche en purines et antécédents familiaux.
#2
Qui est à risque de goutte ?
Les hommes, les personnes obèses et celles ayant des antécédents familiaux de goutte.
#3
Quels médicaments augmentent le risque d'hyperuricémie ?
Diurétiques, aspirine à faible dose et certains médicaments immunosuppresseurs.
#4
Quel rôle de l'alimentation dans les purines ?
Une alimentation riche en viandes rouges, fruits de mer et boissons sucrées augmente le risque.
#5
Comment l'âge influence-t-il l'hyperuricémie ?
Le risque d'hyperuricémie augmente avec l'âge, surtout chez les hommes après 40 ans.
Contenu validé par Dr Olivier Menir
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 18/04/2025
Contenu vérifié selon les dernières recommandations médicales
Sous-catégories
31 au total
└─
Adénine
AdenineD000225 -
D03.633.100.759.138
└─
Allopurinol
AllopurinolD000493 -
D03.633.100.759.160
└─
Mercaptopurine
MercaptopurineD015122 -
D03.633.100.759.570
└─
Purinones
PurinonesD011688 -
D03.633.100.759.758
└─
Roscovitine
RoscovitineD000077546 -
D03.633.100.759.776
└─
Citrate de sildénafil
Sildenafil CitrateD000068677 -
D03.633.100.759.824
└─
Tioguanine
ThioguanineD013866 -
D03.633.100.759.854
└─└─
Amino-2 purine
2-AminopurineD015075 -
D03.633.100.759.138.050
└─└─
Cytokinine
CytokininsD003583 -
D03.633.100.759.138.525
└─└─
Famciclovir
FamciclovirD000077595 -
D03.633.100.759.138.703
└─└─
Ténofovir
TenofovirD000068698 -
D03.633.100.759.138.881
└─└─
Hypoxanthines
HypoxanthinesD007042 -
D03.633.100.759.758.399
└─└─
Xanthines
XanthinesD014970 -
D03.633.100.759.758.824
└─└─└─
Kinétine
KinetinD007701 -
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└─└─└─
Zéatine
ZeatinD015026 -
D03.633.100.759.138.525.700
└─└─└─
Guanine
GuanineD006147 -
D03.633.100.759.758.399.454
└─└─└─
Hypoxanthine
HypoxanthineD019271 -
D03.633.100.759.758.399.475
└─└─└─
Caféine
CaffeineD002110 -
D03.633.100.759.758.824.175
└─└─└─
Théobromine
TheobromineD013805 -
D03.633.100.759.758.824.651
└─└─└─
Théophylline
TheophyllineD013806 -
D03.633.100.759.758.824.751
└─└─└─
Acide urique
Uric AcidD014527 -
D03.633.100.759.758.824.877
└─└─└─
Xanthine
XanthineD019820 -
D03.633.100.759.758.824.938
└─└─└─└─
Aciclovir
AcyclovirD000212 -
D03.633.100.759.758.399.454.250
└─└─└─└─
8-Azaguanine
AzaguanineD001375 -
D03.633.100.759.758.399.454.300
└─└─└─└─
Pentoxifylline
PentoxifyllineD010431 -
D03.633.100.759.758.824.651.700
└─└─└─└─
Diphylline
DyphyllineD004400 -
D03.633.100.759.758.824.751.250
└─└─└─└─
Xanthine(isobutyl-3 methyl-1)
1-Methyl-3-isobutylxanthineD015056 -
D03.633.100.759.758.824.751.500
└─└─└─└─
Nicotinate de xanthinol
Xanthinol NiacinateD014971 -
D03.633.100.759.758.824.751.950
└─└─└─└─└─
Ganciclovir
GanciclovirD015774 -
D03.633.100.759.758.399.454.250.300
└─└─└─└─└─
Valaciclovir
ValacyclovirD000077483 -
D03.633.100.759.758.399.454.250.650
└─└─└─└─└─└─
Valganciclovir
ValganciclovirD000077562 -
D03.633.100.759.758.399.454.250.300.500
Auteurs principaux
Bertrand Daignan-Fornier
3 publications dans cette catégorie
Affiliations :
- Institut de Biochimie et Génétique Cellulaires, CNRS, UMR 5095, Université de Bordeaux, F-33000 Bordeaux, France.
Publications dans "Purines" :
-
Purine Biosynthesis Pathways Are Required for Myogenesis in
Cells 2023-09-28
-
Yeast to Study Human Purine Metabolism Diseases.
Cells 2019-01-17
-
Genetic investigation of purine nucleotide imbalance in Saccharomyces cerevisiae.
Current genetics 2020-08-11
Benoît Pinson
3 publications dans cette catégorie
Affiliations :
- Institut de Biochimie et Génétique Cellulaires, CNRS, UMR 5095, Université de Bordeaux, F-33000 Bordeaux, France.
Publications dans "Purines" :
-
Purine Biosynthesis Pathways Are Required for Myogenesis in
Cells 2023-09-28
-
Yeast to Study Human Purine Metabolism Diseases.
Cells 2019-01-17
-
Genetic investigation of purine nucleotide imbalance in Saccharomyces cerevisiae.
Current genetics 2020-08-11
M Zaeem Cader
2 publications dans cette catégorie
Affiliations :
- Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
Rodrigo Pereira de Almeida Rodrigues
2 publications dans cette catégorie
Affiliations :
- Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
James A West
2 publications dans cette catégorie
Affiliations :
- Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK.
Publications dans "Purines" :
Gavin W Sewell
2 publications dans cette catégorie
Affiliations :
- Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
Muhammad N Md-Ibrahim
2 publications dans cette catégorie
Affiliations :
- Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
Lukas W Unger
2 publications dans cette catégorie
Affiliations :
- Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
Ana Belén Iglesias-Romero
2 publications dans cette catégorie
Affiliations :
- Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
Katharina Ramshorn
2 publications dans cette catégorie
Affiliations :
- Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
Lea-Maxie Haag
2 publications dans cette catégorie
Affiliations :
- Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
Svetlana Saveljeva
2 publications dans cette catégorie
Affiliations :
- Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
Nicole C Kaneider
2 publications dans cette catégorie
Affiliations :
- Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
James C Lee
2 publications dans cette catégorie
Affiliations :
- Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
Trevor D Lawley
2 publications dans cette catégorie
Affiliations :
- Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
Publications dans "Purines" :
Allan Bradley
2 publications dans cette catégorie
Affiliations :
- Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
Publications dans "Purines" :
Gordon Dougan
2 publications dans cette catégorie
Affiliations :
- Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Infectious Diseases, Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
Arthur Kaser
2 publications dans cette catégorie
Affiliations :
- Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK. Electronic address: ak729@cam.ac.uk.
Publications dans "Purines" :
Wei Jiang
2 publications dans cette catégorie
Affiliations :
- Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering , South China University of Technology , Guangzhou 510641 , P. R. China.
Publications dans "Purines" :
-
Direct Sulfenylation of the Purine C
The Journal of organic chemistry 2020-01-14
-
Iodine-catalyzed oxidative functionalization of purines with (thio)ethers or methylarenes for the synthesis of purin-8-one analogues.
Organic & biomolecular chemistry
Juanping Zhuge
2 publications dans cette catégorie
Affiliations :
- Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering , South China University of Technology , Guangzhou 510641 , P. R. China.
Publications dans "Purines" :
-
Direct Sulfenylation of the Purine C
The Journal of organic chemistry 2020-01-14
-
Iodine-catalyzed oxidative functionalization of purines with (thio)ethers or methylarenes for the synthesis of purin-8-one analogues.
Organic & biomolecular chemistry
Sources (10000 au total)
[Contrast Media Toxicity and Its Prevention].
Intravenous iodinated contrast media are commonly used in clinical practice, ranging from medical imaging to interventional radiology (IR) procedures and endovascular interventions. Compared with pati...
Contrast media volume reduction with the DyeVert
Contrast associated acute kidney injury (CA-AKI) can lead to an increased risk of adverse events. Contrast media (CM) volume reduction has been advocated as a pivotal strategy to prevent CA-AKI in sta... To compare the effectiveness of CM volume reduction with the DyeVert... We prospectively collected data from 136 patients with stable coronary artery disease at high risk of CA-AKI treated with left ventricular end diastolic pressure (LVEDP)- guided hydration and undergoi... Patients in the DyeVert group were treated with a significant lower CM volume (median: 47.5 vs. 84.0 mL, p < 0.001). The trend in creatinine increase was lower (p = 0.004) and the Δ of creatinine (0-4... CM volume reduction with the DyeVert...
Iodinated Contrast Media Conservation Measures During a Global Shortage: Effect on Contrast Media Use at a Large Health System.
The aim of this study was to quantify the effect of iodinated contrast media (ICM) conservation measures implemented at a single health system during a global shortage, comparing the 12-month period b...
Strategies for calculating contrast media dose for chest CT.
Total body weight (TBW) is a frequently used contrast media (CM) strategy for dose calculation in enhanced CT, yet it is suboptimal as it lacks consideration of patient characteristics, such as body f... Eighty-nine adult patients referred for CM thoracic CT were retrospectively included, categorized as either normal, muscular, or overweight. Patient body composition data was used to calculate the CM ... BIA demonstrated the highest and lowest calculated CM dose in muscular and overweight groups respectively, compared to other strategies. For the normal group, the lowest calculated CM dose was achieve... The BIA method is more adaptive to variations in patient body habitus especially in muscular and overweight patients and is most closely correlated to patient demographics. This study could support ut... The BIA-based method is adaptive to variations in body habitus especially in muscular and overweight patients and is closely correlated to patient demographics for contrast-enhanced chest CT.... • Calculations based on BIA showed the largest variation in CM dose. • Lean body weight using BIA demonstrated the strongest correlation to patient demographics. • Lean body weight BIA protocol may be...
Impact of iodinated contrast media conserving interventions and lessons for the future.
A severe shortage of iodinated contrast medium (ICM) has forced radiology departments around the world to implement strategies to reduce contrast utilization. The aim of this study was to evaluate the... Our radiology department instituted several ICM-conserving interventions on 13... The average daily number of CECT (all), CECT (inpatient and ED), CTPA, CECT AP, and 'Code stroke' CT scans decreased significantly (P < 0.01), by 58.6%, 68.8%, 74.1%, 88.0%, and 37.5%, respectively. T... Interventions in CT alone, focused on improving patient triage to CECT while avoiding deferment of any outpatient oncology studies, have achieved an approximately two-thirds reduction in ICM consumpti...
Contrast media extravasation injury: a prospective observational cohort study.
To identify the risk factors for moderate and severe contrast media extravasation and provide effective guidance to reduce the degree of extravasation injuries.... We observed 224 adult patients who underwent contrast media extravasation at Xiangya Hospital of Central South University, Hunan Provincial Maternal and Child Healthcare Hospital, and Xiangya Changde ... Among 224 patients, 0 (0%) had severe, 18 (8.0%) had moderate, and 206 (92.0%) had mild contrast media extravasation injury. Multivariate logistic regression analysis revealed malignant tumors (odds r... Risk factors for moderate contrast media extravasation injury are malignant tumors, iohexol, large-volume (> 50 mL) extravasation, and back-of-the-hand injection. Analysis of these risk factors can he... High-risk patients with extravasation support should choose the appropriate contrast media type, avoiding back-of-the-hand injections. We recommend that patients with cancer be implanted with a high-p...
Contrast Media Adverse Drug Reactions in Highly Polluted Environment.
Iodinated- (ICM) and gadolinium-based (GCM) contrast media are used in radiology imaging techniques, such as computer tomography (CT) and magnetic resonance (MR), respectively. The paper aims to analy...
[The atorvastatin effects on the prevention of contrast-induced acute kidney injury during computed tomography with contrast media].
To assess the role of atorvastatin to the frequency of contrast-induced acute kidney injury (CI-AKI) in patients with cardiovascular diseases (CVD) undergoing computed tomography (CT) with intravenous... One hundred patients with CVD undergoing CT with with intravenous contrast media administration were included in prospective observational study (ClinicalTrials.gov ID NCT04666389). Patients were divi... CI-AKI was diagnosed in 4 (3.96%) patients. At the same time, it was not possible to establish statistically significant relationships (p0.05) between risk factors and the development of CI-AKI. Stati... Cardiovascular diseases may increase the risk of CI-AKI after computed tomography with intravenous contrast media administration. Therefore, it is recommended to evaluate the serum creatinine concentr...
Imaging human lung perfusion with contrast media: A meta-analysis.
To pool and summarise published data of pulmonary blood flow (PBF), pulmonary blood volume (PBV) and mean transit time (MTT) of the human lung, obtained with perfusion MRI or CT to provide reliable re... PubMed was systematically searched to identify studies that quantified PBF/PBV/MTT in the human lung by injection of contrast agent, imaged by MRI or CT. Only data analysed by 'indicator dilution theo... PBV was obtained from 313 measurements from 14 publications (wM: 13.97 ml/100 ml, wSD: 4.21 ml/100 ml, wCoV 0.30). MTT was obtained from 188 measurements from 10 publications (wM: 5.91 s, wSD: 1.84 s ... Reference values for PBF, MTT and PBV were obtained in HV. The literature data are insufficient to draw strong conclusions regarding disease reference values....