questionsmedicales.fr
Composés hétérocycliques
Composés hétérocycliques à cycles fusionnés
Composés hétérobicycliques
Purines
Purines : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Hyperuricémie
Acide urique
Goutte
Analyse du liquide synovial
Maladies métaboliques
Tests génétiques
Purines
Troubles métaboliques
Symptômes
5
Hyperuricémie
Douleur articulaire
Troubles métaboliques
Fatigue
Maladie de Wilson
Troubles neurologiques
Prévention
5
Hyperuricémie
Régime alimentaire
Calculs rénaux
Hydratation
Purines
Régime alimentaire
Acide urique
Surveillance médicale
Traitements
5
Hyperuricémie
Inhibiteurs de la xanthine oxydase
Goutte
Anti-inflammatoires non stéroïdiens
Troubles métaboliques
Uricosuriques
Calculs rénaux
Hydratation
Complications
5
Goutte
Arthrite chronique
Hyperuricémie
Maladies rénales
Néphropathie urique
Hyperuricémie
Troubles métaboliques
Problèmes hépatiques
Goutte
Dommages articulaires
Facteurs de risque
5
Goutte
Antécédents familiaux
Hyperuricémie
Diurétiques
Purines
Régime alimentaire
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"position": 19,
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"@type": "Question",
"name": "Quels risques liés à l'hyperuricémie ?",
"position": 22,
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"text": "Peut entraîner des calculs rénaux, des maladies rénales et des problèmes cardiovasculaires."
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"@type": "Question",
"name": "Comment l'hyperuricémie affecte-t-elle les reins ?",
"position": 23,
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}
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"@type": "Question",
"name": "Quelles complications des troubles des purines ?",
"position": 24,
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"@type": "Question",
"name": "Quels effets à long terme de la goutte ?",
"position": 25,
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}
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"@type": "Question",
"name": "Quels facteurs de risque pour l'hyperuricémie ?",
"position": 26,
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"text": "Obésité, consommation excessive d'alcool, régime riche en purines et antécédents familiaux."
}
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"@type": "Question",
"name": "Qui est à risque de goutte ?",
"position": 27,
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"text": "Les hommes, les personnes obèses et celles ayant des antécédents familiaux de goutte."
}
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"@type": "Question",
"name": "Quels médicaments augmentent le risque d'hyperuricémie ?",
"position": 28,
"acceptedAnswer": {
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"text": "Diurétiques, aspirine à faible dose et certains médicaments immunosuppresseurs."
}
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"position": 29,
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"name": "Comment l'âge influence-t-il l'hyperuricémie ?",
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 18/04/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Institut de Biochimie et Génétique Cellulaires, CNRS, UMR 5095, Université de Bordeaux, F-33000 Bordeaux, France.
Publications dans "Purines" :
3 publications dans cette catégorie
Affiliations :
Institut de Biochimie et Génétique Cellulaires, CNRS, UMR 5095, Université de Bordeaux, F-33000 Bordeaux, France.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Infectious Diseases, Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK. Electronic address: ak729@cam.ac.uk.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering , South China University of Technology , Guangzhou 510641 , P. R. China.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering , South China University of Technology , Guangzhou 510641 , P. R. China.
Publications dans "Purines" :
The purpose of this study was to test the hypothesis that an individualized exercise training target heart rate (HR) based on a maximal graded exercise test (GXT) is associated with greater improvemen...
Chronic Obstructive Pulmonary Disease (COPD) is a disease that is spreading worldwide and is responsible for a huge number of deaths annually. It is characterized by progressive and often irreversible...
Background and Objectives: Muscle blood flow is impeded during resistance exercise contractions, but immediately increases during recovery. The purpose of this study was to determine the impact of bri...
Patients with chronic obstructive pulmonary disease (COPD) have difficulties inhaling as the diaphragm becomes flattened and weakened due to lung hyperinflation. This weakened respiratory function is ...
This study aimed to evaluate the difference in the SCM thickening fraction (SCM TF) of each respiratory phase (end-expiration, resting inspiration, and end-inspiration), as measured using ultrasonogra...
Patients with COPD (n = 44) and age-matched controls (n = 20) underwent US for determination of the SCM TF. Ventilation parameters, including the peak oxygen uptake (peak VO2) and the change in the in...
The SCM was significantly thinner in patients with COPD than in controls at end-expiration. The increase in the SCM TF from end-expiration to end-inspiration in patients with COPD did not differ signi...
The SCM may be thinner in patients with COPD than in controls. The SCM TF may also be associated with exercise tolerance....
What is the central question of this study? Does prescribing exercise intensity using physiological thresholds create a more homogeneous exercise stimulus than using traditional intensity anchors? Wha...
The objective of this study was to determine whether the variability in exercise tolerance and physiological responses is lower when exercise is prescribed relative to physiological thresholds (THR) c...
Patients with multiple sclerosis (MS) experience reduced exercise tolerance that substantially reduces quality of life. The mechanisms underpinning exercise intolerance in MS are not fully clear. This...
Twenty-three patients with MS (13 women) and 20 age-matched and sex-matched healthy controls (13 women) performed a cardiopulmonary exercise test. Muscle fibre type composition, size, succinate dehydr...
Patients with MS had lower maximal oxygen uptake compared with healthy controls (V̇O...
Skeletal muscle oxidative phenotype (mitochondrial complex I and II content, SDH activity) is lower in patients with MS, contributing to reduced exercise tolerance. However, skeletal muscle mitochondr...
Following ST-segment elevation myocardial infarction (STEMI), patients with cardiac dysfunction have limitations in performing physical activity. Right ventricular (RV) function is a determinant in im...
To evaluate the association of RV function with exercise tolerance after a CR program in patients with STEMI....
Retrospective cohort study in patients with STEMI from January to December 2019. They underwent an echocardiographic assessment of RV function before a 16-session CR program. A cardiopulmonary exercis...
A total of 109 patients were included. Of all, 3.7% had global RV dysfunction, 10.1% had radial RV dysfunction, and 11% had longitudinal RV dysfunction. An association between radial or longitudinal R...
RV dysfunction is associated with a lower capacity to exercise; CR programs can be extended or modified in these patients....
The Buffalo Concussion Treadmill Test (BCTT) is a standard assessment of exercise tolerance utilized for exercise prescription following concussion and to inform decisions regarding return to play. On...
Prospective cohort study, pretest/posttest....
A total of 30 participants included 13 women (43.3%), age 23.4 (1.93) years, height 173.56 (10) cm, weight 77.35 (16.3) kg, and 11 (36.7%) with history of concussion. All participants completed a neur...
BCTT: Average percentage of heart rate maximum (%HRmax) = 93.97% (4.8%); average maximum rating of perceived exertion = 18.6 (1.5). Time-based performance in single-task and dual-task conditions signi...
Healthy participants demonstrated improvements across multiple domains of neurocognitive performance following the exercise tolerance testing on the BCTT. Understanding normal responses in neurocognit...
Critical torque (CT) and work done above it ( W ') are key predictors of exercise performance associated with neuromuscular fatigue. The aim of the present study was to understand the role of the meta...
Twelve subjects performed four knee extension time trials (6, 8, 10, and 12 min) using eccentric, isometric, or concentric contractions (3-s on/2-s off at 90°·s -1 or 30°·s -1 ) to modulate the metabo...
Compared with isometric exercise, total impulse (+36% ± 21%; P < 0.001), CT (+27% ± 30%; P < 0.001), and W ' (+67% ± 99%; P < 0.001) were increased during eccentric exercise, whereas total impulse (-2...
The contraction mode influenced both CT and W ', and consequently exercise tolerance, indicating that the metabolic cost of contraction played a key role....
In patients with chronic obstructive pulmonary disease (COPD), the clinical use of the minute ventilation-carbon dioxide production ([Formula: see text]...
We hypothesized that the [Formula: see text]...
Compared with the GOLD I-II group (n = 51), peak [Formula: see text]...
The OUES may be less useful in advanced COPD with exertional hypoxemia. The [Formula: see text]...