questionsmedicales.fr
Composés hétérocycliques
Composés hétérocycliques à cycles fusionnés
Composés hétérobicycliques
Purines
Purines : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Hyperuricémie
Acide urique
Goutte
Analyse du liquide synovial
Maladies métaboliques
Tests génétiques
Purines
Troubles métaboliques
Symptômes
5
Hyperuricémie
Douleur articulaire
Troubles métaboliques
Fatigue
Maladie de Wilson
Troubles neurologiques
Prévention
5
Hyperuricémie
Régime alimentaire
Calculs rénaux
Hydratation
Purines
Régime alimentaire
Acide urique
Surveillance médicale
Traitements
5
Hyperuricémie
Inhibiteurs de la xanthine oxydase
Goutte
Anti-inflammatoires non stéroïdiens
Troubles métaboliques
Uricosuriques
Calculs rénaux
Hydratation
Complications
5
Goutte
Arthrite chronique
Hyperuricémie
Maladies rénales
Néphropathie urique
Hyperuricémie
Troubles métaboliques
Problèmes hépatiques
Goutte
Dommages articulaires
Facteurs de risque
5
Goutte
Antécédents familiaux
Hyperuricémie
Diurétiques
Purines
Régime alimentaire
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"@type": "Question",
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"name": "Comment évaluer une maladie liée aux purines ?",
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"name": "Quels symptômes des troubles des purines ?",
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"name": "Quels symptômes d'une maladie de Wilson ?",
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"position": 14,
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}
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"@type": "Question",
"name": "Quel traitement pour la goutte ?",
"position": 17,
"acceptedAnswer": {
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"text": "Anti-inflammatoires non stéroïdiens (AINS) et colchicine pour soulager la douleur."
}
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"@type": "Question",
"name": "Comment prévenir les crises de goutte ?",
"position": 18,
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}
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"name": "Quels médicaments pour les troubles des purines ?",
"position": 19,
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"@type": "Question",
"name": "Comment gérer les calculs rénaux liés aux purines ?",
"position": 20,
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}
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"@type": "Question",
"name": "Quelles complications de la goutte ?",
"position": 21,
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"text": "Arthrite chronique, dépôts de tophus et risque accru de maladies cardiovasculaires."
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"@type": "Question",
"name": "Quels risques liés à l'hyperuricémie ?",
"position": 22,
"acceptedAnswer": {
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"text": "Peut entraîner des calculs rénaux, des maladies rénales et des problèmes cardiovasculaires."
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"@type": "Question",
"name": "Comment l'hyperuricémie affecte-t-elle les reins ?",
"position": 23,
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"text": "Peut provoquer une néphropathie urique, entraînant des lésions rénales."
}
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"@type": "Question",
"name": "Quelles complications des troubles des purines ?",
"position": 24,
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"text": "Peuvent inclure des problèmes hépatiques, neurologiques et des troubles métaboliques."
}
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{
"@type": "Question",
"name": "Quels effets à long terme de la goutte ?",
"position": 25,
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}
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{
"@type": "Question",
"name": "Quels facteurs de risque pour l'hyperuricémie ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Obésité, consommation excessive d'alcool, régime riche en purines et antécédents familiaux."
}
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{
"@type": "Question",
"name": "Qui est à risque de goutte ?",
"position": 27,
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"text": "Les hommes, les personnes obèses et celles ayant des antécédents familiaux de goutte."
}
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"@type": "Question",
"name": "Quels médicaments augmentent le risque d'hyperuricémie ?",
"position": 28,
"acceptedAnswer": {
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"text": "Diurétiques, aspirine à faible dose et certains médicaments immunosuppresseurs."
}
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"@type": "Question",
"name": "Quel rôle de l'alimentation dans les purines ?",
"position": 29,
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"text": "Une alimentation riche en viandes rouges, fruits de mer et boissons sucrées augmente le risque."
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"name": "Comment l'âge influence-t-il l'hyperuricémie ?",
"position": 30,
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 18/04/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Institut de Biochimie et Génétique Cellulaires, CNRS, UMR 5095, Université de Bordeaux, F-33000 Bordeaux, France.
Publications dans "Purines" :
3 publications dans cette catégorie
Affiliations :
Institut de Biochimie et Génétique Cellulaires, CNRS, UMR 5095, Université de Bordeaux, F-33000 Bordeaux, France.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Infectious Diseases, Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK. Electronic address: ak729@cam.ac.uk.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering , South China University of Technology , Guangzhou 510641 , P. R. China.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering , South China University of Technology , Guangzhou 510641 , P. R. China.
Publications dans "Purines" :
There is evidence for increased resistance against the antimicrobials used to treat keratitis. This review aims to provide global and regional prevalence estimates of antimicrobial resistance in corne...
We report this protocol following Preferred Reporting Items for Systematic Review and Meta-Analyses Protocols guidelines. We will conduct an electronic bibliographic search in MEDLINE, EMBASE, Web of ...
Ethics approval is not required as this is a protocol for a systematic review of published data. The findings of this review will be published in an open-access, peer-reviewed journal....
CRD42023331126....
Tranexamic acid (TXA) has become a widely used antifibrinolytic drug for reducing bleeding in surgery. However, adverse events, such as seizures, pulmonary embolism and deep vein thrombosis, limit its...
We will search the PubMed, Cochrane Central Register of Controlled Trials, Embase, Web of Science and China National Knowledge Internet databases using a strategy that combines the terms TXA, randomis...
CRD42021281206....
Androgenetic alopecia is a widespread condition that is the most common type of hair loss affecting approximately 58% and 40% of men and women by the age of 50, respectively. Patients have been known ...
Systematic review with meta-analysis integrates findings from multiple studies, offering robust conclusions on treatment effects and guiding evidence-based medicine. However, the process is often hamp...
Meta-Analysis Accelerator was developed to address these challenges. The tool offers 21 different statistical conversions, including median & interquartile range (IQR) to mean & standard deviation (SD...
Since its initial release in October 2023 as Meta Converter and subsequent renaming to Meta-Analysis Accelerator, the tool has gained widespread use globally. From March 2024 to May 2024, it received ...
Meta-Analysis Accelerator significantly enhances the efficiency and accuracy of meta-analysis of systematic reviews by providing a reliable platform for statistical data conversion. Its comprehensive ...
Severely calcified coronary stenoses are difficult to treat with percutaneous coronary interventions. The presence of severe calcifications complicates lesion preparation, advancement of stents and ac...
We will conduct a systematic review of randomised trials enrolling patients with calcified coronary artery disease undergoing percutaneous coronary intervention. We will investigate any percutaneous t...
No ethics approval is required for this study. The results will be published in a peer-reviewed journal in this field....
CRD42021226034....
Network meta-analysis (NMA) expands upon traditional meta-analysis by integrating three or more interventions. This allows comparing interventions using evidence from trials that have compared pairs o...
Several methods are commonly used for meta-analyses of diagnostic studies, such as the bivariate linear mixed model (LMM). It estimates the overall sensitivity, specificity, their correlation, diagnos...
We compared the bivariate LMM and GLMM using the relative differences in the overall sensitivity and specificity, their 95% CI widths, between-study variances, and the correlation between the (logit) ...
Among the extracted 1379 meta-analyses, point estimates of overall sensitivities and specificities by the bivariate LMM and GLMM were generally similar, but their CI widths could be noticeably differe...
The variation of estimates calls into question the appropriateness of the normality assumption within individual studies required by the bivariate LMM. In cases of notable differences presented in the...
Collaborative care interventions have been proposed as a promising strategy to support patients with multimorbidity. Despite this, the effectiveness of collaborative care interventions requires furthe...
This systematic review aims to systematically assess the effectiveness of collaborative care interventions in comparison to usual care concerning health-related quality of life (HRQoL), mental health,...
Randomized controlled trials evaluating collaborative care interventions designed for adult patients (18 years and older) with multimorbidity compared with usual care will be considered for inclusion ...
The preliminary literature search was performed on February 16, 2024, and yielded 5255 unique records. A follow-up search will be performed across all databases before submission. The findings will be...
This review will provide an overview of pooled estimates of treatment effects across HRQoL, mental health, and mortality from randomized controlled trials evaluating collaborative care interventions f...
International Prospective Register of Systematic Reviews (PROSPERO) CRD42024512554; https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=512554....
DERR1-10.2196/58296....
Meta-analyses constitute fundamental tools of the Evidence-Based Medicine (EBM) aiming at synthesizing outcome data from individual trials in order to produce pooled effect estimates for various outco...
Bayesian methods seem a natural choice for combining sources of evidence in meta-analyses. However, in practice, their sensitivity to the choice of prior distribution is much less attractive, particul...